Research Topics
| H OpenshawSummaryAffiliation: City of Hope National Medical Center Country: USA Publications
| Collaborators
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Detail Information
Publications
High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosisRichard A Nash
Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D1 100, PO Box 19024, Seattle, WA 98109 1024, USA
Blood 102:2364-72. 2003..This was a heterogeneous high-risk group, and a phase 3 study is planned to fully assess efficacy...
Lumbar puncture and subdural hygroma and hematomas in hematopoietic cell transplant patientsH Openshaw
Department of Neurology, City of Hope National Medical Center, Duarte, CA 91010 3000, USA
Bone Marrow Transplant 41:791-5. 2008....
Multiple sclerosis conference synopsis and discussion: cellular therapy for treatment of autoimmune diseases (October 2005)H Openshaw
Department of Neurology, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USA
Mult Scler 12:824-5. 2006..A discussion panel considered questions on how to define success, timing of controlled clinical trials, difficulty in patient recruitment, and future direction of high dose therapy...- Unilateral mydriasis from ipratropium in transplant patientsHarry Openshaw
Department of Neurology, City of Hope National Medical Center, 1500 E. Duarte Rd, Duarte, CA 91010, USA
Neurology 67:914. 2006 - The effect of height on paclitaxel nerve damageHarry Openshaw
Department of Neurology, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010 3000, USA
J Neurooncol 74:207-10. 2005..Nerve length is probably one of these factors. To determine whether the effect of height is clinically important would require additional study with a larger number of subjects and longer clinical follow-up... - Kernohan notch lesion after spinal tapHarry Openshaw
Department of Neurology, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010-3000
Neurology 64:1631. 2005 - Neurophysiological study of peripheral neuropathy after high-dose Paclitaxel: lack of neuroprotective effect of amifostineHarry Openshaw
Department of Neurology, City of Hope National Medical Center, Duarte, California 91010, USA
Clin Cancer Res 10:461-7. 2004..To determine if there is a beneficial effect of amifostine in preventing or reducing the neuropathy induced by high-dose paclitaxel... - High-dose immunosuppression and hematopoietic stem cell transplantation in autoimmune disease: clinical reviewHarry Openshaw
City of Hope National Medical Center, Duarte, California 91010, USA
Biol Blood Marrow Transplant 8:233-48. 2002..Parallel trials in Europe and in the United States are in the late stages of design... - Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoringH Openshaw
Department of Neurology, City of Hope National Medical Center, Duarte, California 91010, USA
Biol Blood Marrow Transplant 6:563-75. 2000..Further studies and longer follow-up would be needed to determine the significance of new lymphocyte proliferative responses after SCT and the overall effect of this treatment on the natural history of MS... - Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factorH Openshaw
Department of Neurology, City of Hope National Medical Center, Duarte, CA 91010, USA
Neurology 54:2147-50. 2000..There was improvement when methylprednisolone was given to three of the patients, but one patient died of respiratory failure. The mechanism of the neurologic worsening is uncertain... - Role for gamma interferon in control of herpes simplex virus type 1 reactivationE Cantin
Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010 3012, USA
J Virol 73:3418-23. 1999..0002), and 33% in RGKO mice (P = 0.03). We concluded that IFN-gamma is not involved in the induction of reactivation but rather contributes to rapid suppression of HSV once it is reactivated... - Gender influences herpes simplex virus type 1 infection in normal and gamma interferon-mutant miceX Han
Department of Virology, City of Hope National Medical Center, Duarte, California 91010, USA
J Virol 75:3048-52. 2001..In addition, the results comparing GKO and RGKO mice to controls show differences only in male mice, suggesting that some effects of IFN-gamma, a key immunoregulatory molecule, are gender specific... - Gamma interferon (IFN-gamma) receptor null-mutant mice are more susceptible to herpes simplex virus type 1 infection than IFN-gamma ligand null-mutant miceE Cantin
Department of Neurology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA
J Virol 73:5196-200. 1999.... - Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosisImke Metz
Department of Neuropathology, Georg August University, Gottingen, Germany
Brain 130:1254-62. 2007.... - Feasibility of allogeneic hematopoietic stem cell transplantation for autoimmune disease: position statement from a National Institute of Allergy and Infectious Diseases and National Cancer Institute-Sponsored International Workshop, Bethesda, MD, March 1Linda M Griffith
Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Biol Blood Marrow Transplant 11:862-70. 2005 - Intradermal doxorubicin reduces ganglionic reactivation of latent herpes simplex virus in mice after pretreatment with hypertonic salineTsuyoshi Sekizawa
Department of Neurology, Tohoku University School of Medicine, Sendai, Japan
J Med Virol 70:263-6. 2003..Skin toxicity may preclude doxorubicin use for HSV recurrences in patients; however, the results of this study support the concept of anti-HSV treatment via retrograde axoplasmic transport...