S S Mahajan

Summary

Affiliation: City University of New York
Country: USA

Publications

  1. pmc Synergistic inhibition of survival, proliferation, and migration of U87 cells with a combination of LY341495 and Iressa
    Zarina Yelskaya
    Department of Health Sciences, Hunter College, City University of New York, New York, New York, United States of America
    PLoS ONE 8:e64588. 2013
  2. pmc Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing
    S S Mahajan
    School of Health Sciences, Hunter College, CUNY, New York, NY 10010, USA
    Neuroscience 189:305-15. 2011
  3. pmc Novel toxicity of the unedited GluR2 AMPA receptor subunit dependent on surface trafficking and increased Ca2+-permeability
    S S Mahajan
    The Department of Biochemistry, New York University School of Medicine, 550 First Avenue, New York, NY 1006, USA
    Mol Cell Neurosci 35:470-81. 2007

Collaborators

  • E B Ziff
  • Zarina Yelskaya
  • Vangie Carrillo
  • Ewa Dubisz
  • Devon Morgan
  • Hira Gulzar

Detail Information

Publications3

  1. pmc Synergistic inhibition of survival, proliferation, and migration of U87 cells with a combination of LY341495 and Iressa
    Zarina Yelskaya
    Department of Health Sciences, Hunter College, City University of New York, New York, New York, United States of America
    PLoS ONE 8:e64588. 2013
    ..These results demonstrate that a combinatorial therapy with Iressa and LY341495 is more effective due to synergistic effects of these drugs in inhibiting the growth of glioblastoma...
  2. pmc Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing
    S S Mahajan
    School of Health Sciences, Hunter College, CUNY, New York, NY 10010, USA
    Neuroscience 189:305-15. 2011
    ..We demonstrate that cleaved ADAR2 leads to a decrease or loss of GluR2 editing, which will further result in high Ca2+ influx and excitotoxic neuronal death...
  3. pmc Novel toxicity of the unedited GluR2 AMPA receptor subunit dependent on surface trafficking and increased Ca2+-permeability
    S S Mahajan
    The Department of Biochemistry, New York University School of Medicine, 550 First Avenue, New York, NY 1006, USA
    Mol Cell Neurosci 35:470-81. 2007
    ..Peptide block of trafficking provides a model for design of drugs to reduce unedited GluR2 excitotoxicity in neurodegenerative diseases that result from editing failure...