Research Topics
Species | Deborah J MacDonaldSummaryAffiliation: City of Hope National Medical Center Country: USA Publications
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Detail Information
Publications
Closing the loop: an interactive action-research conference format for delivering updated medical information while eliciting Latina patient/family experiences and psychosocial needs post-genetic cancer risk assessmentDeborah J MacDonald
Division of Clinical Cancer Genetics, City of Hope An NCI Designated Comprehensive Cancer Center, 1500 E Duarte Rd, Duarte, CA 91010, USA
Fam Cancer 11:449-58. 2012..Findings informed GCRA process improvements and provide a basis for theory-driven cancer control research...
Germline mutations in cancer susceptibility genes: an overview for nursesDeborah J MacDonald
Division of Clinical Cancer Genetics, Department of Population Science, City of Hope Comprehensive Cancer Center, 1500 E Duarte Road, Duarte, CA 91010, USA
Semin Oncol Nurs 27:21-33. 2011..To provide an overview of hereditary cancer susceptibility genes and associated cancer risks...
Women's perceptions of the personal and family impact of genetic cancer risk assessment: focus group findingsDeborah J MacDonald
Division of Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center, 1500 E Duarte Rd, Duarte, CA 91010 3000, USA
J Genet Couns 19:148-60. 2010..Additional research is needed to extend these findings and identify interventions to support positive outcomes of GCRA...
Comparison of Latina and non-Latina white women's beliefs about communicating genetic cancer risk to relativesDeborah J MacDonald
Cancer Screening and Prevention Program, Clinical Cancer Genetics Department, City of Hope Cancer Center, Duarte, California 91010 3000, USA
J Health Commun 13:465-79. 2008..15-5.66), Latina ethnicity (odds ratio [OR] 0.22, 95% CI, 0.09-0.53), and Spanish as primary language (OR, 0.17, 95% CI, 0.06-0.47) were independently associated with the belief that a clinician should be the informant...
Hereditary cancers in children and ethical and psychosocial implicationsD J MacDonald
Department of Clinical Cancer Genetics, City of Hope National Medical Center, Duarte, CA 91010 3000, USA
J Pediatr Nurs 15:217-25. 2000..Basic cancer genetics concepts are reviewed. Specific hereditary cancers that may affect children are described along with case examples and recommendations for nursing practice...
Selection of family members for communication of cancer risk and barriers to this communication before and after genetic cancer risk assessmentDeborah J MacDonald
Clinical Cancer Genetics Department, City of Hope Cancer Center, Duarte, California 91010 3000, USA
Genet Med 9:275-82. 2007..We compared women's selection of family members for cancer risk communication and perceived barriers to this communication before genetic cancer risk assessment and 6 months afterward...
Cancer screening and risk-reducing behaviors of women seeking genetic cancer risk assessment for breast and ovarian cancersDeborah J MacDonald
Clinical Cancer Genetics Department, City of Hope Cancer Center, Duarte, CA, USA
Oncol Nurs Forum 33:E27-35. 2006..To examine breast and ovarian cancer screening and risk-reducing behaviors of women seeking genetic cancer risk assessment (GCRA)...
Health beliefs of women with and without breast cancer seeking genetic cancer risk assessmentDeborah J MacDonald
Clinical Cancer Genetics Department, City of Hope Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Cancer Nurs 28:372-9; quiz 380-1. 2005..Nurses are in a prime position to assist women seeking GCRA by providing accurate information and emotional support regarding cancer risk, risk factors, and genetic testing...
Limited family structure and BRCA gene mutation status in single cases of breast cancerJeffrey N Weitzel
Department of Clinical Cancer Genetics, City of Hope, 1500 E Duarte Rd, Duarte, CA 91010, USA
JAMA 297:2587-95. 2007..An autosomal dominant pattern of hereditary breast cancer may be masked by small family size or transmission through males given sex-limited expression...
Closing the loop: action research in a multimodal hereditary cancer patient conference is an effective tool to assess and address patient needsCarin R Espenschied
Division of Clinical Cancer Genetics, City of Hope, 1500 E Duarte Rd, Duarte, CA, 91010, USA
J Cancer Educ 27:467-77. 2012..Insights gained yielded valuable feedback to inform clinical care, future health services research, and continuing medical education activities. These methods may also be effective in other practice settings...
Beliefs and interest in cancer risk in an underserved Latino cohortCharité N Ricker
City of Hope National Medical Center, Clinical Cancer Genetics Department, Duarte, CA 91010, USA
Prev Med 44:241-5. 2007..To measure beliefs about cancer causation, cancer screening behaviors, access to information about and resources for cancer screening, and interest in cancer genetics services in two underserved predominantly Latino communities...
Development and evaluation of a decision aid for BRCA carriers with breast cancerJulie O Culver
Division of Clinical Cancer Genetics, Department of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010 3000, USA
J Genet Couns 20:294-307. 2011..Stakeholders were divided as to whether the DA should be offered at-home versus only in a clinical setting. This well-received DA will be further tested to determine accessibility and effectiveness...
Outcomes from intensive training in genetic cancer risk counseling for cliniciansKathleen R Blazer
Department of Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, California, USA
Genet Med 7:40-7. 2005..Courses such as this can help address the need for competent cancer risk assessment services in communities outside the academic health center...
Personalized cancer genetics training for personalized medicine: improving community-based healthcare through a genetically literate workforceKathleen R Blazer
Division of Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center, Duarte, California 91010, USA
Genet Med 13:832-40. 2011..Clinicians are increasingly requested to conduct genetic cancer risk assessment, but many are inadequately prepared to provide these services...
Extending comprehensive cancer center expertise in clinical cancer genetics and genomics to diverse communities: the power of partnershipDeborah J MacDonald
Division of Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center, Duarte, California 91010, USA
J Natl Compr Canc Netw 8:615-24. 2010....
Influence of genetic discrimination perceptions and knowledge on cancer genetics referral practice among cliniciansKatrina J Lowstuter
Department of Clinical Cancer Genetics, City of Hope, Duarte, California 91010, USA
Genet Med 10:691-8. 2008..To describe nongenetics clinicians' perceptions and knowledge of cancer genetics and laws prohibiting genetic discrimination, attitudes toward the use of cancer genetic testing, and referral practices...
Women's decisions regarding management of breast cancer riskDeborah J MacDonald
City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Medsurg Nurs 11:183-6. 2002..Their perceptions related to breast cancer risk management options have implications for practicing nurses...
Linkage of a pedigree drawing program and database to a program for determining BRCA mutation carrier probabilitySharon R Sand
Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center, 1500 East Duarte Rd, Modular 103, Duarte, CA 9101, USA
Fam Cancer 4:313-6. 2005..An export module was developed for transferring primary relational pedigree data directly from a widely used pedigree program and relational database to the BRCAPRO program for calculation of BRCA gene mutation probability estimation...
Effect of genetic cancer risk assessment on surgical decisions at breast cancer diagnosisJeffrey N Weitzel
Department of Clinical Cancer Genetics, City of Hope National Medical Center, Duarte, CA 91010, USA
Arch Surg 138:1323-8; discussion 1329. 2003..Breast cancer gene (BRCA) mutation status affects patients' surgical decisions when genetic cancer risk assessment is offered at the time of breast cancer diagnosis, prior to definitive treatment...
Reflex immunohistochemistry and microsatellite instability testing of colorectal tumors for Lynch syndrome among US cancer programs and follow-up of abnormal resultsLaura C Beamer
City of Hope, Duarte, CA 91010, USA
J Clin Oncol 30:1058-63. 2012..The purpose of this study was to describe prevalent practices regarding IHC/MSI reflex testing for LS in the United States and the subsequent follow-up of abnormal results...
Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriersJeffrey N Weitzel
Department of Clinical Cancer Genetics, City of Hope Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Clin Cancer Res 13:654-8. 2007..We evaluated the efficacy, safety, and tolerability of hormonal chemoprevention with a gonadotropin-releasing hormone agonist (GnRHA) with low-dose add-back steroids in BRCA1(mut) carriers...
Creating tomorrow's leaders in cancer prevention: a novel interdisciplinary career development program in cancer genetics researchKathleen R Blazer
City of Hope Cancer Center, Duarte, CA 91010, USA
J Cancer Educ 21:216-22. 2006..To prepare oncology, genetics and molecular medicine professionals for basic, translational and epidemiological cancer genetics research through advanced training in a novel specialized cancer genetics career development program (CGCDP)...
Development of a cancer genetics education program for cliniciansKathleen R Blazer
Department of Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, California 91010, USA
J Cancer Educ 17:69-73. 2002..There is a gap in knowledge about hereditary cancer and genetic testing among primary care practitioners. Education is needed to enable identification and management of patients at high risk for cancer...
Effects of a cancer genetics education programme on clinician knowledge and practiceK R Blazer
Department of Clinical Cancer Genetics, City of Hope Comprehensive Cancer Center and Beckman Research Institute, 1500 East Duarte Road, Duarte, CA 91010, USA
J Med Genet 41:518-22. 2004..Many clinicians lack adequate knowledge about emerging standards of care related to genetic cancer risk assessment and the features of hereditary cancer needed to identify patients at risk...
Breast cancer risk reductionTherese B Bevers
National Comprehensive Cancer Network
J Natl Compr Canc Netw 5:676-701. 2007
