Edward J Kennelly

Summary

Affiliation: City University of New York
Country: USA

Publications

  1. ncbi request reprint Analysis of thirteen populations of black cohosh for formononetin
    E J Kennelly
    Department of Biological Sciences, Lehman College and The Center for Graduate Studies, The City University of New York, Bronx, NY 10468, USA
    Phytomedicine 9:461-7. 2002
  2. doi request reprint Phenolic-rich extract from the Costa Rican guava (Psidium friedrichsthalianum) pulp with antioxidant and anti-inflammatory activity. Potential for COPD therapy
    Gema Flores
    Department of Biological Sciences, Lehman College and The Graduate Center, City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, USA
    Food Chem 141:889-95. 2013
  3. doi request reprint Phytochemical fingerprinting to thwart black cohosh adulteration: a 15 Actaea species analysis
    Bei Jiang
    Department of Biological Science, Lehman College and The Graduate Center, City University of New York, Bronx, NY 10468, USA
    Phytochem Anal 22:339-51. 2011
  4. doi request reprint Antioxidant and metabolite profiling of North American and neotropical blueberries using LC-TOF-MS and multivariate analyses
    Chunhui Ma
    Department of Biological Sciences, Lehman College, The City University of New York, Bronx, New York 10468, United States
    J Agric Food Chem 61:3548-59. 2013
  5. doi request reprint Antioxidant glucosylated caffeoylquinic acid derivatives in the invasive tropical soda apple, Solanum viarum
    Shi Biao Wu
    Department of Biological Sciences, Lehman College, 250 Bedford Park Boulevard West, Bronx, New York 10468, USA
    J Nat Prod 75:2246-50. 2012
  6. pmc Synergistic interactions between carotene ring hydroxylases drive lutein formation in plant carotenoid biosynthesis
    Rena F Quinlan
    Department of Biological Sciences, Lehman College, City University of New York, Bronx, New York 10468, USA
    Plant Physiol 160:204-14. 2012
  7. doi request reprint Edible Myrciaria vexator fruits: bioactive phenolics for potential COPD therapy
    Keyvan Dastmalchi
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, United States
    Bioorg Med Chem 20:4549-55. 2012
  8. doi request reprint Increase in cone biomass and terpenophenolics in hops ( Humulus lupulus L.) by treatment with prohexadione-calcium
    Adam R Kavalier
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, USA
    J Agric Food Chem 59:6720-9. 2011
  9. pmc Benzophenones and biflavonoids from Rheedia edulis
    Ulyana Muñoz Acuña
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, New York 10468, United States
    J Nat Prod 73:1775-9. 2010
  10. pmc Edible neotropical blueberries: antioxidant and compositional fingerprint analysis
    Keyvan Dastmalchi
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York, United States
    J Agric Food Chem 59:3020-6. 2011

Collaborators

  • Selena Ahmed
  • Amy Litt
  • Chunlin Long
  • Linda Saxe Einbond
  • Jing Wu
  • Kan He
  • Jun Ma
  • Rachel S Meyer
  • J A Roach
  • Chunhui Ma
  • Shi Biao Wu
  • Bei Jiang
  • Keyvan Dastmalchi
  • Adam R Kavalier
  • Gema Flores
  • Kurt A Reynertson
  • Hui Yang
  • Ulyana Muñoz Acuña
  • Fredi Kronenberg
  • Paiboon Nuntanakorn
  • Louis M T Bradbury
  • Paul D Matthews
  • Bruce D Whitaker
  • Mario Figueroa
  • Adam Kavalier
  • Margaret J Basile
  • Robert F Foronjy
  • Abdoulaye J Dabo
  • Jeanine M D Armiento
  • Kathleen Whalen
  • Eleanore T Wurtzel
  • Maria Shumskaya
  • Rena F Quinlan
  • Paola Pedraza-Peñalosa
  • Amy C Keller
  • Nicholi J Pitra
  • Mark C Coles
  • Uchenna J Unachukwu
  • Nikola Jancovski
  • James T Lyles
  • I Bernard Weinstein
  • Andreana L Ososki
  • DWIGHT KINCAID
  • Jinzhu Zhang
  • Zhiwei Yin
  • Shengping Zheng
  • Oren Tzfadia
  • Jesús Beltrán
  • Jared M Koelling
  • Anne Marie B Brillantes
  • Vanya Petrova
  • Timothy Motley
  • Scott Baggett
  • Satoshi To
  • Miguel Cervantes-Cervantes
  • Ming Hua Qiu
  • William Raynor
  • Michael J Balick
  • Roberta Lee
  • Yosio Pelep
  • Daniel E Atha
  • Michael H Nee

Detail Information

Publications35

  1. ncbi request reprint Analysis of thirteen populations of black cohosh for formononetin
    E J Kennelly
    Department of Biological Sciences, Lehman College and The Center for Graduate Studies, The City University of New York, Bronx, NY 10468, USA
    Phytomedicine 9:461-7. 2002
    ..Therefore, the clinically observed estrogen-like actions of black cohosh, such as reduction of hot flashes, are likely due to a compound, or combination of compounds, other than formononetin...
  2. doi request reprint Phenolic-rich extract from the Costa Rican guava (Psidium friedrichsthalianum) pulp with antioxidant and anti-inflammatory activity. Potential for COPD therapy
    Gema Flores
    Department of Biological Sciences, Lehman College and The Graduate Center, City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, USA
    Food Chem 141:889-95. 2013
    ....
  3. doi request reprint Phytochemical fingerprinting to thwart black cohosh adulteration: a 15 Actaea species analysis
    Bei Jiang
    Department of Biological Science, Lehman College and The Graduate Center, City University of New York, Bronx, NY 10468, USA
    Phytochem Anal 22:339-51. 2011
    ..Correct plant species identification is a key first step for good manufacturing practices of safe black cohosh products...
  4. doi request reprint Antioxidant and metabolite profiling of North American and neotropical blueberries using LC-TOF-MS and multivariate analyses
    Chunhui Ma
    Department of Biological Sciences, Lehman College, The City University of New York, Bronx, New York 10468, United States
    J Agric Food Chem 61:3548-59. 2013
    ....
  5. doi request reprint Antioxidant glucosylated caffeoylquinic acid derivatives in the invasive tropical soda apple, Solanum viarum
    Shi Biao Wu
    Department of Biological Sciences, Lehman College, 250 Bedford Park Boulevard West, Bronx, New York 10468, USA
    J Nat Prod 75:2246-50. 2012
    ..The antioxidant activities determined by ABTS(•+) and DPPH(•) assays were in the order 1 > 2 > 5-CQA...
  6. pmc Synergistic interactions between carotene ring hydroxylases drive lutein formation in plant carotenoid biosynthesis
    Rena F Quinlan
    Department of Biological Sciences, Lehman College, City University of New York, Bronx, New York 10468, USA
    Plant Physiol 160:204-14. 2012
    ..These findings will facilitate efforts to manipulate carotenoid content and composition for improving plant adaptation to climate change and/or for enhancing nutritionally important carotenoids in food crops...
  7. doi request reprint Edible Myrciaria vexator fruits: bioactive phenolics for potential COPD therapy
    Keyvan Dastmalchi
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, United States
    Bioorg Med Chem 20:4549-55. 2012
    ....
  8. doi request reprint Increase in cone biomass and terpenophenolics in hops ( Humulus lupulus L.) by treatment with prohexadione-calcium
    Adam R Kavalier
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, USA
    J Agric Food Chem 59:6720-9. 2011
    ..Induced changes in cone biomass production and terpenophenolic accumulation were most dependent on cultivar and the developmental stage at which plants were treated...
  9. pmc Benzophenones and biflavonoids from Rheedia edulis
    Ulyana Muñoz Acuña
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, New York 10468, United States
    J Nat Prod 73:1775-9. 2010
    ..Compound 1 showed significant antioxidant activity in both DPPH and ABTS free radical scavenging assays, whereas compound 2 was inactive...
  10. pmc Edible neotropical blueberries: antioxidant and compositional fingerprint analysis
    Keyvan Dastmalchi
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York, United States
    J Agric Food Chem 59:3020-6. 2011
    ..Each fruit species formed its own cluster, and therefore the antioxidant profile of each species was shown to be distinct...
  11. doi request reprint White and green teas (Camellia sinensis var. sinensis): variation in phenolic, methylxanthine, and antioxidant profiles
    Uchenna J Unachukwu
    Dept of Biological Sciences, Lehman College, Bronx, NY 10468, USA
    J Food Sci 75:C541-8. 2010
    ....
  12. doi request reprint A new liquid chromatography-mass spectrometry-based strategy to integrate chemistry, morphology, and evolution of eggplant (Solanum) species
    Shi Biao Wu
    Department of Biological Sciences, Lehman College and The Graduate Center, City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, USA
    J Chromatogr A 1314:154-72. 2013
    ....
  13. doi request reprint Targeted analysis of polyphenol metabolism during development of hop (Humulus lupulus L.) cones following treatment with prohexadione-calcium
    Adam R Kavalier
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, USA Electronic address
    Food Chem 145:254-63. 2014
    ..The methods developed here serve to compliment flavour analysis of polyphenol rich foods, and our results suggest ways to improve upon traditional agricultural methods to produce hops with altered chemical profiles. ..
  14. pmc Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro
    Amy C Keller
    Lehman College and The Graduate Center, City University of New York, Bronx, NY 10468, USA
    Phytomedicine 19:32-7. 2011
    ..007, and p=0.002, respectively. This is the first report of a saponin-rich fraction, and isolated compounds from M. charantia, stimulating insulin secretion in an in vitro, static incubation assay...
  15. doi request reprint Two new antioxidant malonated caffeoylquinic acid isomers in fruits of wild eggplant relatives
    Chunhui Ma
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, United States
    J Agric Food Chem 59:9645-51. 2011
    ..To the authors' knowledge, these two malonylcaffeoylquinic acid isomers have not previously been reported...
  16. ncbi request reprint Detecting potential teratogenic alkaloids from blue cohosh rhizomes using an in vitro rat embryo culture
    E J Kennelly
    Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, 200 C Street SW, Washington, D C 20204, USA
    J Nat Prod 62:1385-9. 1999
    ..Thalictroidine, anagyrine, and alpha-isolupanine were not teratogenic in the REC at tested concentrations. Taspine (2) showed high embryotoxicity, but no teratogenic activity, in the REC...
  17. doi request reprint Phytochemical and morphological characterization of hop (Humulus lupulus L.) cones over five developmental stages using high performance liquid chromatography coupled to time-of-flight mass spectrometry, ultrahigh performance liquid chromatography photodi
    Adam R Kavalier
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, New York 10468, United States
    J Agric Food Chem 59:4783-93. 2011
    ..The methods reported here can be used for targeted metabolic profiling of flavonoids, phenolic acids, and terpenophenolics in hops, and are applicable to quantitation in other crops...
  18. ncbi request reprint Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric
    Linda Saxe Einbond
    Lehman College and The Graduate Center, CUNY, Bronx, NY 10468, USA
    Anticancer Agents Med Chem 13:1540-50. 2013
    ..These studies indicate the potential of benzophenones, alone or combined with sulindac sulfide or turmeric, to prevent and treat colon cancer. ..
  19. doi request reprint Bioactive and marker compounds from two edible dark-colored Myrciaria fruits and the synthesis of jaboticabin
    Shi Biao Wu
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York, United States 10468
    J Agric Food Chem 61:4035-43. 2013
    ..Jaboticabin, a minor bioactive depside, occurred in both fruits and, because of its potential to treat chronic obstructive pulmonary disease, was successfully synthesized in the laboratory. ..
  20. pmc Metabolic profiling of Actaea species extracts using high performance liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry
    Chunhui Ma
    Department of Biological Sciences, Lehman College and The Graduate Center, City University of New York, 250 Bedford Park Boulevard W, Bronx, NY 10468, USA
    J Chromatogr A 1218:1461-76. 2011
    ..The use of metabolic profiling to distinguish black cohosh from related species of Actaea has broader implications in the identification of markers to help authenticate other important medicinal plants...
  21. pmc Lycopene cyclase paralog CruP protects against reactive oxygen species in oxygenic photosynthetic organisms
    Louis M T Bradbury
    Department of Biological Sciences, Lehman College, City University of New York, West, Bronx, NY 10468, USA
    Proc Natl Acad Sci U S A 109:E1888-97. 2012
    ..Therefore, CruP represents a unique target for developing resilient plants and algae needed to supply food and biofuels in the face of global climate change...
  22. doi request reprint Stability evaluation of selected polyphenols and triterpene glycosides in black cohosh
    Bei Jiang
    Department of Biological Sciences, Lehman College and The Graduate Center, City University of New York, Bronx, New York 10468, USA
    J Agric Food Chem 56:9510-9. 2008
    ..The rate of compound decomposition depended upon the chemical structure of the individual polyphenols. Polyphenols in the extracts decomposed more readily than those in plant material...
  23. ncbi request reprint Polyisoprenylated benzophenones from Clusiaceae: potential drugs and lead compounds
    Ulyana Muñoz Acuña
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, New York 10468, USA
    Curr Top Med Chem 9:1560-80. 2009
    ..The structure-activity relationships of polyisoprenylated benzophenones from natural sources and those of synthetic analogues are included in this review. Absorption, metabolism, and elimination of benzophenones are also discussed...
  24. doi request reprint Benzophenones and biflavonoids from Garcinia livingstonei fruits
    Hui Yang
    Department of Biological Sciences, Lehman College, The City University of New York, Bronx, New York 10468, USA
    J Agric Food Chem 58:4749-55. 2010
    ..Both compounds exhibited strong activity against HCT-116 and HT-29 cell lines with IC(50) values between 5 and 10 microM, and somewhat weaker activity with SW-480 cells (IC(50) values ranging from 18 to 25 microM)...
  25. pmc Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry
    Bei Jiang
    The Richard and Hinda Rosenthal Center for Complementary and Alternative Medicine, Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Agric Food Chem 54:3242-53. 2006
    ..For the products containing only black cohosh, there was significant product-to-product variability in the amounts of the selected triterpene glycosides and phenolic constituents, and as expected, no formononetin was detected...
  26. ncbi request reprint Antioxidant capacities of ten edible North American plants
    Ulyana Muñoz Acuña
    Division of Pharmacognosy, University of Uppsala, Box 579, S 751 23 Uppsala, Sweden
    Phytother Res 16:63-5. 2002
    ....
  27. ncbi request reprint Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Anticancer Res 27:697-712. 2007
    ..Our aim is to identify alterations in gene expression induced by treatment with a methanolic extract (MeOH) of black cohosh...
  28. ncbi request reprint Phytoestrogens: a review of the present state of research
    Andreana L Ososki
    Biological Sciences, Lehman College, City University of New York, 250 Bedford Park Blvd West, Bronx, NY 10468, USA
    Phytother Res 17:845-69. 2003
    ..The effects of phytoestrogens on breast and prostate cancers, cardiovascular disease, menopausal symptoms and osteoporosis will also be examined including research on benefits and risks...
  29. ncbi request reprint Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, 701 W 168th Street, New York, NY 10032, USA
    Planta Med 72:1200-6. 2006
    ....
  30. ncbi request reprint Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells
    Linda Saxe Einbond
    Herbert Irvign Comperhensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Breast Cancer Res Treat 83:221-31. 2004
    ..Further studies are in progress to identify the mechanisms by which actein and related compounds present in black cohosh inhibit growth of human breast cancer cells...
  31. ncbi request reprint Analysis of polyphenolic antioxidants from the fruits of three pouteria species by selected ion monitoring liquid chromatography-mass spectrometry
    Jun Ma
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, USA
    J Agric Food Chem 52:5873-8. 2004
    ..The levels of the seven polyphenols corresponded with the results of the 1,1-diphenyl-2-picrylhydrazyl assay, by which P. sapota had the highest antioxidant activity, P. viridis the second highest, and P. campechiana the lowest...
  32. ncbi request reprint A traditional method of Cinnamomum carolinense preparation eliminates safrole from a therapeutic Pohnpean tea
    Kurt A Reynertson
    Lehman College and The Graduate Center, City University of New York, 250 Bedford Park Boulevard West, Bronx, NY 10468, USA
    J Ethnopharmacol 102:269-74. 2005
    ..The limit of detection and limit of quantitation of safrole were determined to be 1.25 and 3.75 microg/mL, respectively. The traditional preparation method, which boils the bark shavings, degrades the safrole...
  33. ncbi request reprint Polyphenolic constituents of Actaea racemosa
    Paiboon Nuntanakorn
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, New York 10468, USA
    J Nat Prod 69:314-8. 2006
    ..Compounds 1 and 2 also exhibited a small stimulating effect on the growth of MCF-7 breast cancer cell proliferation 1.24-fold (14 microM) and 1.14-fold (10 microM), respectively, compared to untreated cells...
  34. ncbi request reprint Comparative analyses of bioactive Mammea coumarins from seven parts of Mammea americana by HPLC-PDA with LC-MS
    Hui Yang
    Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, USA
    J Agric Food Chem 54:4114-20. 2006
    ..Additionally, the described HPLC-PDA and LC-MS methods are sensitive and accurate and can be applied to the analysis of mammea coumarins in other samples...
  35. pmc Analysis of polyphenolic compounds and radical scavenging activity of four American Actaea species
    Paiboon Nuntanakorn
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, NY 10468, USA
    Phytochem Anal 18:219-28. 2007
    ..The radical scavenging activity of the Actaea extracts correlates to their polyphenolic composition. This validated HPLC method can be used to distinguish A. racemosa from the other major American Actaea species based on this study...