Research Topics
| Jeffrey HalperinSummaryAffiliation: City University of New York Country: USA Publications
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Detail Information
Publications
Revisiting the role of the prefrontal cortex in the pathophysiology of attention-deficit/hyperactivity disorderJeffrey M Halperin
Department of Psychology, Queens College of the City University of New York, Flushing, NY 11367, USA
Psychol Bull 132:560-81. 2006..Data supporting this neurodevelopmental model of prefrontal cortex function in ADHD are reviewed. Research and treatment implications are discussed...- The interaction of psychosocial adversity and biological risk in childhood aggressionDavid J Marks
Division of Child and Adolescent Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Psychiatry Res 151:221-30. 2007..In contrast, no such interaction was observed for teacher-rated aggression. Findings suggest that individuals at biological risk for aggression may be particularly vulnerable to the impact of psychosocial adversity... 
Preventive interventions for ADHD: a neurodevelopmental perspectiveJeffrey M Halperin
Department of Psychology, Queens College of the City University of New York, Flushing, New York 11367, USA
Neurotherapeutics 9:531-41. 2012..Finally, we review recent studies in young children with ADHD that might fall under the umbrella of secondary prevention...- Childhood CBCL bipolar profile and adolescent/young adult personality disorders: a 9-year follow-upJeffrey M Halperin
Department of Psychology, Queens College of the City University of New York, NY 11367, United States
J Affect Disord 130:155-61. 2011..To assess the late adolescent psychiatric outcomes associated with a positive Child Behavior Checklist-Juvenile Bipolar Disorder Phenotype (CBCL-JBD) in children diagnosed with ADHD and followed over a 9-year period... - The influences of environmental enrichment, cognitive enhancement, and physical exercise on brain development: can we alter the developmental trajectory of ADHD?Jeffrey M Halperin
Department of Psychology, Queens College of the City University of New York 11367, USA
Neurosci Biobehav Rev 35:621-34. 2011.... - Neuropsychological outcome in adolescents/young adults with childhood ADHD: profiles of persisters, remitters and controlsJeffrey M Halperin
Department of Psychology, Queens College, City University of New York, NY 11367, USA
J Child Psychol Psychiatry 49:958-66. 2008..In contrast, persisters and remitters were hypothesized to perform similarly, and different from controls, on tasks requiring less effortful processing... - Elevated childhood serotonergic function protects against adolescent aggression in disruptive boysJeffrey M Halperin
Psychology Department, Queens College, 65 30 Kissena Boulevard, Flushing, NY 11367, USA
J Am Acad Child Adolesc Psychiatry 45:833-40. 2006..This longitudinal study examined whether responsiveness of the neurotransmitter serotonin (5-HT) in childhood predicts adolescent aggression... - Adolescents with childhood ADHD and comorbid disruptive behavior disorders: aggression, anger, and hostilitySeth C Harty
CUNY Graduate Center, Neuropsychology Doctoral Program, Flushing, NY 11367, USA
Child Psychiatry Hum Dev 40:85-97. 2009..This study examined the self-reported expression of overt aggressive behaviors and covert emotional and cognitive processes in adolescents diagnosed with ADHD and comorbid disruptive behavior disorders (DBDs) during childhood... - Prenatal exposure to maternal and paternal smoking on attention deficit hyperactivity disorders symptoms and diagnosis in offspringYoko Nomura
Department of Psychology, Queens College, The City University of New York, Flushing, NY 10029, USA
J Nerv Ment Dis 198:672-8. 2010..Although father's smoking was not associated with an increased risk, as it strongly influenced mothers' smoking, intervention for both parents may be most effective in preventing the pathway to ADHD-related problems in the children... - Familial correlates of central serotonin function in children with disruptive behavior disordersJeffrey M Halperin
Department of Psychology, Queens College of CUNY, 65 30 Kissena Boulevard, Flushing, NY 11367, USA
Psychiatry Res 119:205-16. 2003..These data suggest that there are both familial and non-familial forms of aggression in children, and that only the familial type is associated with reduced 5-HT function... - Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorderJanine D Flory
Department of Psychology, Queens College, City University of New York, 65 30 Kissena Boulevard, SB 318 Flushing, NY 11367, USA
Br J Psychiatry 190:410-4. 2007..Impulsive aggression in adulthood is associated with disturbances in serotonergic function. In contrast, research examining this association in childhood has yielded inconsistent results... - Comparison of measured and estimated cognitive ability in older adolescents with and without ADHDCarlin J Miller
Department of Psychology, Queens College, City University of New York, 6530 Kissena Blvd, Flushing, NY 11367, USA
J Atten Disord 9:444-50. 2005.... - Reliability, validity, and preliminary normative data for the Children's Aggression Scale-Teacher VersionJeffrey M Halperin
Department of Psychology, Queens College of the City University of New York, USA
J Am Acad Child Adolesc Psychiatry 42:965-71. 2003..To provide preliminary psychometric data on the Children's Aggression Scale-Teacher Version (CAS-T), which was designed to assess severity and frequency of aggressive, as distinct from nonaggressive, disruptive behaviors... - Childhood maltreatment and conduct disorder: independent predictors of adolescent substance use disorders in youth with attention deficit/hyperactivity disorderVirginia A De Sanctis
Graduate Center of the City University of New York, Flushing, NY 11367, USA
J Clin Child Adolesc Psychol 37:785-93. 2008..Childhood maltreatment predicted SUD outcome over and above that accounted for by childhood conduct disorder and problematic parental substance use, two potent predictors of adolescent SUDs... - Auditory selective attention and processing in children with attention-deficit/hyperactivity disorderHilary Gomes
Cognitive Neuroscience Program, City College of New York, CUNY, New York, NY 10031, USA
Clin Neurophysiol 123:293-302. 2012..This study sought to better characterize the contributions of deficits in attention allocation and distracter inhibition to the poor performance on attention tasks often seen in children with ADHD... - Psychomotor slowing as a predictor of fluoxetine nonresponse in depressed outpatientsBonnie P Taylor
Depression Evaluation Service, New York State Psychiatric Institute, Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Dr, New York, NY 10032, USA
Am J Psychiatry 163:73-8. 2006..The authors hypothesized that since psychomotor slowing in depressed patients has been linked to reduced dopaminergic neurotransmission, patients with slowing would be unresponsive to fluoxetine, a selective serotonin reuptake inhibitor... - Family and cognitive factors: modeling risk for aggression in children with ADHDCarlin J Miller
Department of Psychology, Queens College, City University of New York, Flushing 11367, USA
J Am Acad Child Adolesc Psychiatry 45:355-63. 2006..To explore the relationships of family and cognitive factors to aggression as reported by parents and teachers... - Self-report and objective measures of ADHD-related behaviors in parents of preschool children at risk for ADHDElizabeth A Curko Kera
Neuropsychology Program, City University of New York Graduate Center, Queens College, Flushing, NY, USA
CNS Spectr 9:639-47. 2004..Further research is needed to more clearly identify the specific nature of these neuropsychological deficits and to determine whether they have a negative impact on their children... - Development, reliability, and validity of the children's aggression scale-parent versionJeffrey M Halperin
Department of Psychology, Queens College of the City University of New York, and Mount Sinai School of Medicine, Flushing 11367, USA
J Am Acad Child Adolesc Psychiatry 41:245-52. 2002..To provide preliminary psychometric data on the Children's Aggression Scale-Parent Version (CAS-P), which assesses severity, frequency, pervasiveness, and diversity of aggressive, as distinct from nonaggressive, disruptive behaviors... - Stimulant treatment in children with attention-deficit/hyperactivity disorder moderates adolescent academic outcomeRobyn L Powers
The Graduate Center, City University of New York, New York, NY, USA
J Child Adolesc Psychopharmacol 18:449-59. 2008..Psychostimulant treatment for children with ADHD may benefit long-term adolescent academic performance, although the extent of improvement is likely to vary as a function of multiple factors... 
Usefulness of a clinician rating scale in identifying preschool children with ADHDChaya Gopin
City University of New York, USA
J Atten Disord 13:479-88. 2010..To ascertain the psychometric properties and clinical utility of the Behavioral Rating Inventory for Children (BRIC), a novel clinician inventory for preschoolers...- Brief report: Television viewing and risk for attention problems in preschool childrenCarlin J Miller
Department of Psychology, Queens College, City University of New York, USA
J Pediatr Psychol 32:448-52. 2007..This study examined whether high levels of television viewing are associated with attention problems and hyperactivity in preschool children... - Single dissociation findings of ADHD deficits in vigilance but not anterior or posterior attention systemsCynthia L Huang-Pollock
Department of Psychology, Pennsylvania State University, University Park, PA 16802, USA
Neuropsychology 20:420-9. 2006..However, consistent with previous meta-analytic work, there was no evidence for anterior or posterior system orienting dysfunctions in either subtype... - The relationship of behavioral inhibition to executive functions in young adultsAngeles M Cheung
Neuropsychology Subprogram of the Ph.D. Program in Psychology, Graduate School and University Center, City University of New York, NY 11367, USA
J Clin Exp Neuropsychol 26:393-404. 2004..These findings provide partial support for Barkley's theory in that effective executive functioning is associated with sufficient inhibitory control... - Dissociation of perceptual and motor inhibition processes through the use of novel computerized conflict tasksKatharine W Nassauer
Neuropsychology Doctoral Subprogram, Department of Psychology, The Graduate School, University Center of the City University of New York, New York, NY 11367, USA
J Int Neuropsychol Soc 9:25-30. 2003..Nevertheless, performance on the two conflict tasks was significantly correlated with each other, and Perceptual Conflict performance was significantly correlated with Stroop interference... - Sustained attention and response inhibition in young children at risk for Attention Deficit/Hyperactivity DisorderOlga G Berwid
Department of Psychology, The Graduate School and University Center of The City University of New York, USA
J Child Psychol Psychiatry 46:1219-29. 2005..CONCLUSIONS: ADHD-associated decrements in performance on these tasks appear to be attributable either to generalized behavioral dysregulation or poor state regulation rather than to deficient inhibitory control... - Growth hormone response to guanfacine in boys with attention deficit hyperactivity disorder: a preliminary studyJeffrey M Halperin
Department of Psychology, Queens College of the City University of New York, New York, New York 11367, USA
J Child Adolesc Psychopharmacol 13:283-94. 2003.... - Personality characteristics associated with persistent ADHD in late adolescenceCarlin J Miller
Department of Psychology, University of Windsor, 401 Sunset Avenue, Windsor, Ontario N9B 3P4, Canada
J Abnorm Child Psychol 36:165-73. 2008..These results suggest that ADHD, and the degree to which symptoms persist into adolescence, may be closely linked to personality structure... - Lack of seasonal rhythms in central serotonergic function in boys with ADHDKurt P Schulz
Neuropsychology Subprogram of the PhD Program in Psychology, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, NY 1016, USA
Psychoneuroendocrinology 27:463-73. 2002..These results indicate that seasonality-related variance is not a threat to the validity of the neurochemical procedure and does not account for the inconsistencies in the studies of central 5-HT and aggression in children with ADHD... - Juvenile maladaptive aggression: a review of prevention, treatment, and service configuration and a proposed research agendaDaniel F Connor
Department of Psychiatry MC1410, University of Connecticut Health Center, Farmington 06030 1410, USA
J Clin Psychiatry 67:808-20. 2006..To propose a research agenda for disorders of aggression in child and adolescent psychiatry... - Adolescent outcome of ADHD: impact of childhood conduct and anxiety disordersJeffrey H Newcorn
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
CNS Spectr 9:668-78. 2004..the negative behavioral outcome of youth with ADHD?; and (4) Is there an interaction between comorbid CD and anxiety disorders, when they occur simultaneously, that predicts a different outcome than either comorbid condition alone?.. - The effect of childhood conduct disorder and cognitive functioning on adolescent substance useSeth C Harty
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
CNS Spectr 9:661-6. 2004..CONCLUSION: These data indicate that the presence of conduct disorder may interact with high Verbal IQ during childhood in such a way as to predict later adolescent substance use in disruptive behavior disorder populations... - Brain activation gradients in ventrolateral prefrontal cortex related to persistence of ADHD in adolescent boysKurt P Schulz
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Am Acad Child Adolesc Psychiatry 44:47-54. 2005..To explore the possible role that functional abnormalities of the prefrontal cortex and basal ganglia play in the persistence of attention-deficit/hyperactivity disorder (ADHD) in adolescents aged 15 to 19 years... - Differential prefrontal cortex activation during inhibitory control in adolescents with and without childhood attention-deficit/hyperactivity disorderKurt P Schulz
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Neuropsychology 19:390-402. 2005..The magnitude of the prefrontal and basal ganglia activation was positively correlated with severity of ADHD. Response competition alone did not yield group differences in activation... - Neuropsychological correlates of ADHD symptoms in preschoolersDavid J Marks
Division of Child and Adolescent Psychiatry, Mount Sinai Medical Center, New York, NY 10029, USA
Neuropsychology 19:446-55. 2005..Yet, the fact that at-risk preschoolers were highly symptomatic casts doubt on whether executive function deficits and/or frontostriatal networks contribute etiologically to early behavioral manifestations of ADHD... - The impact of impairment criteria on rates of ADHD diagnoses in preschoolersDione M Healey
Department of Psychology, University of Otago, PO Box 56, Dunedin, 9054, New Zealand
J Abnorm Child Psychol 36:771-8. 2008..These findings are discussed in terms of the importance of using impairment criteria, rather than just severity of inattention, impulsivity and hyperactivity, when diagnosing ADHD in preschool children... - Response inhibition in adolescents diagnosed with attention deficit hyperactivity disorder during childhood: an event-related FMRI studyKurt P Schulz
Department of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
Am J Psychiatry 161:1650-7. 2004..The present study used behavioral and functional neuroimaging techniques to examine inhibitory control processes in adolescents who had been diagnosed with ADHD during childhood...
Research Grants
- HETEROGENEITY OF ADHD: PREDICTORS OF ADOLESCENT OUTCOMEJeffrey Halperin; Fiscal Year: 2005....
- ADHD: Neural Correlates of Adult OutcomesJeffrey M Halperin; Fiscal Year: 2010....
- Predictors of Attention Deficit Hyperactivity Disorder in Preschool ChildrenJeffrey Halperin; Fiscal Year: 2009....
- Neurodevelopmental Perspectives on ADHDJeffrey M Halperin; Fiscal Year: 2010..If our hypothesis is confirmed, it could have a significant impact on the development of novel, long-lasting, treatment interventions for this highly impaired group of patients. ..
- ADHD: Neural Correlates of Adult OutcomesJeffrey Halperin; Fiscal Year: 2007....
- Neurodevelopmental Perspectives on ADHDJeffrey M Halperin; Fiscal Year: 2010..If this hypothesis is confirmed, it could have a significant impact on the development of novel treatment interventions. ..