Karl Gaal

Summary

Affiliation: City of Hope National Medical Center
Country: USA

Publications

  1. pmc Evaluation of chronic lymphocytic leukemia by BAC-based microarray analysis
    Roger A Schultz
    Signature Genomics, 2820 N, Astor St, Spokane, WA, 99207, USA
    Mol Cytogenet 4:4. 2011
  2. pmc Assessing karyotype precision by microarray-based comparative genomic hybridization in the myelodysplastic/myeloproliferative syndromes
    Marilyn L Slovak
    Signature Genomics, Spokane, WA, USA
    Mol Cytogenet 3:23. 2010
  3. ncbi request reprint Epstein-Barr virus nuclear antigen (EBNA)-1 carboxy-terminal and EBNA-4 sequence polymorphisms in nasal natural killer/T-cell lymphoma in the United States
    Karl Gaal
    Division of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Lab Invest 82:957-62. 2002
  4. pmc Improved outcomes using tacrolimus/sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis
    David S Snyder
    City of Hope Cancer Center, Department of Hematology HCT, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 16:281-6. 2010
  5. pmc Impact of graft cell dose on transplant outcomes following unrelated donor allogeneic peripheral blood stem cell transplantation: higher CD34+ cell doses are associated with decreased relapse rates
    Ryotaro Nakamura
    Division of Hematology Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010 3000, USA
    Biol Blood Marrow Transplant 14:449-57. 2008
  6. ncbi request reprint Peripheral blood hematopoietic stem cell mobilization and collection efficacy is not an independent prognostic factor for autologous stem cell transplantation
    Shirong Wang
    Department of Transfusion Medicine, Division of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Transfusion 47:2207-16. 2007
  7. doi request reprint Pediatric mast cell sarcoma of temporal bone with novel L799F (2395 C>T) KIT mutation, mimicking histiocytic neoplasm
    Young S Kim
    Department of Pathology, City of Hope National Medical Center, Duarte, CA 91010, USA
    Am J Surg Pathol 37:453-8. 2013
  8. pmc Successful application of a direct detection slide-based sequential phenotype/genotype assay using archived bone marrow smears and paraffin embedded tissue sections
    Victoria Bedell
    Department of Cytogenetics, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USA
    J Mol Diagn 9:589-97. 2007
  9. pmc High-dose therapy and autologous hematopoietic cell transplantation in peripheral T cell lymphoma (PTCL): analysis of prognostic factors
    Auayporn Nademanee
    Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010 3000, USA
    Biol Blood Marrow Transplant 17:1481-9. 2011
  10. ncbi request reprint Allogeneic hematopoietic cell transplantation following reduced intensity conditioning for treatment of myelofibrosis
    David S Snyder
    Division of Hematology Hematopoietic Cell Transplant, City of Hope Cancer Center, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 12:1161-8. 2006

Collaborators

Detail Information

Publications15

  1. pmc Evaluation of chronic lymphocytic leukemia by BAC-based microarray analysis
    Roger A Schultz
    Signature Genomics, 2820 N, Astor St, Spokane, WA, 99207, USA
    Mol Cytogenet 4:4. 2011
    ..abstract:..
  2. pmc Assessing karyotype precision by microarray-based comparative genomic hybridization in the myelodysplastic/myeloproliferative syndromes
    Marilyn L Slovak
    Signature Genomics, Spokane, WA, USA
    Mol Cytogenet 3:23. 2010
    ....
  3. ncbi request reprint Epstein-Barr virus nuclear antigen (EBNA)-1 carboxy-terminal and EBNA-4 sequence polymorphisms in nasal natural killer/T-cell lymphoma in the United States
    Karl Gaal
    Division of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Lab Invest 82:957-62. 2002
    ..S.-reactive and non-U.S.-NL cases. Although the significance of this difference is not known for certain, it may be related to geographic and/or site-specific variations, rather than oncogenicity per se...
  4. pmc Improved outcomes using tacrolimus/sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis
    David S Snyder
    City of Hope Cancer Center, Department of Hematology HCT, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 16:281-6. 2010
    ..We conclude that the combination of tacrolimus/sirolimus+/-MTX for GVHD prophylaxis in the setting of RIC HCT for MF appears to reduce the incidence of severe aGVHD and NRM, and leads to improved OS compared to CSA/MMF+/-MTX...
  5. pmc Impact of graft cell dose on transplant outcomes following unrelated donor allogeneic peripheral blood stem cell transplantation: higher CD34+ cell doses are associated with decreased relapse rates
    Ryotaro Nakamura
    Division of Hematology Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010 3000, USA
    Biol Blood Marrow Transplant 14:449-57. 2008
    ....
  6. ncbi request reprint Peripheral blood hematopoietic stem cell mobilization and collection efficacy is not an independent prognostic factor for autologous stem cell transplantation
    Shirong Wang
    Department of Transfusion Medicine, Division of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Transfusion 47:2207-16. 2007
    ..The aim of this retrospective study was to determine whether the effectiveness of mobilization and collection is an independent prognostic factor for autologous stem cell transplantation outcome...
  7. doi request reprint Pediatric mast cell sarcoma of temporal bone with novel L799F (2395 C>T) KIT mutation, mimicking histiocytic neoplasm
    Young S Kim
    Department of Pathology, City of Hope National Medical Center, Duarte, CA 91010, USA
    Am J Surg Pathol 37:453-8. 2013
    ..Proximity of the L799F mutation to the enzymatic region of the KIT tyrosine kinase domain may induce resistance to tyrosine kinase inhibitors...
  8. pmc Successful application of a direct detection slide-based sequential phenotype/genotype assay using archived bone marrow smears and paraffin embedded tissue sections
    Victoria Bedell
    Department of Cytogenetics, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USA
    J Mol Diagn 9:589-97. 2007
    ..Furthermore, the method has proved reliable and reproducible on test samples regardless of specimen age, tissue type, or referring institution...
  9. pmc High-dose therapy and autologous hematopoietic cell transplantation in peripheral T cell lymphoma (PTCL): analysis of prognostic factors
    Auayporn Nademanee
    Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010 3000, USA
    Biol Blood Marrow Transplant 17:1481-9. 2011
    ..More effective and novel therapies are needed for patients with high-risk disease (PIT 3-4 factors) and allogeneic HCT should be explored in these patients...
  10. ncbi request reprint Allogeneic hematopoietic cell transplantation following reduced intensity conditioning for treatment of myelofibrosis
    David S Snyder
    Division of Hematology Hematopoietic Cell Transplant, City of Hope Cancer Center, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 12:1161-8. 2006
    ..2 months for the living patients. Overall survival probability at 1 year was 55.6% (95% confidence interval, 31.3%-77.4%). These results suggest that RIC MUD HCT using PBSCs can be an effective treatment for older patients with MF...
  11. doi request reprint Does MDS with der(1;7)(q10;p10) constitute a distinct risk group? A retrospective single institutional analysis of clinical/pathologic features compared to -7/del(7q) MDS
    Marilyn L Slovak
    Cytogenetics Laboratory, City of Hope, 1500 E Duarte Road, Duarte, CA 91010, USA
    Cancer Genet Cytogenet 193:78-85. 2009
    ..4, 32.0, and 23.6%, respectively) did not differ significantly (P=0.94). While der(1;7) MDS is associated with some clinically distinctive features, reassignment of risk category based on these data would be premature...
  12. ncbi request reprint Philadelphia chromosome-positive acute lymphoblastic leukemia secondary to chemoradiotherapy for Ewing sarcoma. Report of two cases and concise review of the literature
    David S Snyder
    Division of Hematology, City of Hope National Medical Center, Duarte, CA 91010, USA
    Am J Hematol 78:74-8. 2005
    ..We report herein two cases of young adult patients who were both diagnosed with Ph+ ALL 19 years after successful treatment for ES with combined modality therapy. A review of the relevant literature follows the case reports...
  13. ncbi request reprint Primary effusion lymphoma with subsequent development of a small bowel mass in an HIV-seropositive patient: a case report and literature review
    Qin Huang
    Division of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Am J Surg Pathol 26:1363-7. 2002
    ....
  14. ncbi request reprint Does follicularity in large cell lymphoma predict outcome after autologous stem cell transplantation?
    Amrita Krishnan
    Division of Hematology Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 12:641-7. 2006
    ..Furthermore, the similar plateau in the survival curve for the DLCL and FLCL patients suggests that the behavior of FLCL is similar to that of DLCL and that FLCL is potentially curable with ASCT...
  15. ncbi request reprint Diagnostic utility of bilateral bone marrow examination: significance of morphologic and ancillary technique study in malignancy
    Jun Wang
    Division of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Cancer 94:1522-31. 2002
    ..To retrospectively evaluate the significance of morphologic examination and ancillary studies performed on bilateral bone marrow biopsy specimens, 1864 bone marrow samples were studied...