Janine D Flory

Summary

Affiliation: City University of New York
Country: USA

Publications

  1. ncbi request reprint Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorder
    Janine D Flory
    Department of Psychology, Queens College, City University of New York, 65 30 Kissena Boulevard, SB 318 Flushing, NY 11367, USA
    Br J Psychiatry 190:410-4. 2007
  2. pmc Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene
    Janine D Flory
    Department of Psychology, Queens College and The Graduate Center, City University of New York, New York, NY, USA
    Biol Psychol 88:51-6. 2011
  3. pmc Maternal exposure to the holocaust and health complaints in offspring
    Janine D Flory
    Department of Psychology, Queens College and The Graduate Center, City University of New York, Flushing, USA
    Dis Markers 30:133-9. 2011
  4. pmc Childhood trauma and basal cortisol in people with personality disorders
    Janine D Flory
    Department of Psychology, Queens College CUNY, Flushing, NY 11367, USA
    Compr Psychiatry 50:34-7. 2009
  5. pmc Impulsiveness and cigarette smoking
    Janine D Flory
    Department of Psychology, Queens College, 65 30 Kissena Blvd, Flushing, NY 11367, USA
    Psychosom Med 71:431-7. 2009
  6. ncbi request reprint COMT val158Met and executive control: a test of the benefit of specific deficits to translational research
    Angus W MacDonald
    Department of Psychology, University of Pittsburgh, USA
    J Abnorm Psychol 116:306-12. 2007
  7. ncbi request reprint The socio-economic status of communities predicts variation in brain serotonergic responsivity
    Stephen B Manuck
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA 15260, USA
    Psychol Med 35:519-28. 2005
  8. ncbi request reprint Irritable assault and variation in the COMT gene
    Janine D Flory
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Psychiatr Genet 17:344-6. 2007
  9. ncbi request reprint Central nervous system serotonergic responsivity and aggressive disposition in men
    Stephen B Manuck
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA, USA
    Physiol Behav 77:705-9. 2002
  10. pmc Parental education is related to C-reactive protein among female middle-aged community volunteers
    Jennifer E Phillips
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Brain Behav Immun 23:677-83. 2009

Research Grants

Detail Information

Publications35

  1. ncbi request reprint Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorder
    Janine D Flory
    Department of Psychology, Queens College, City University of New York, 65 30 Kissena Boulevard, SB 318 Flushing, NY 11367, USA
    Br J Psychiatry 190:410-4. 2007
    ..Impulsive aggression in adulthood is associated with disturbances in serotonergic function. In contrast, research examining this association in childhood has yielded inconsistent results...
  2. pmc Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene
    Janine D Flory
    Department of Psychology, Queens College and The Graduate Center, City University of New York, New York, NY, USA
    Biol Psychol 88:51-6. 2011
    ..g., drug use, sexual activity)...
  3. pmc Maternal exposure to the holocaust and health complaints in offspring
    Janine D Flory
    Department of Psychology, Queens College and The Graduate Center, City University of New York, Flushing, USA
    Dis Markers 30:133-9. 2011
    ..The mechanism linking these health outcomes and maternal exposure deserves further investigation, including the possibility that fetal or early developmental programming is involved...
  4. pmc Childhood trauma and basal cortisol in people with personality disorders
    Janine D Flory
    Department of Psychology, Queens College CUNY, Flushing, NY 11367, USA
    Compr Psychiatry 50:34-7. 2009
    ..36, P = .02), after controlling for other forms of abuse. Results are consistent with the view that childhood trauma has long-lasting neurobiological effects and suggest that different forms of trauma may have distinct biological effects...
  5. pmc Impulsiveness and cigarette smoking
    Janine D Flory
    Department of Psychology, Queens College, 65 30 Kissena Blvd, Flushing, NY 11367, USA
    Psychosom Med 71:431-7. 2009
    ..g., any tobacco use versus dependence) or considered more than one variety of impulsiveness simultaneously...
  6. ncbi request reprint COMT val158Met and executive control: a test of the benefit of specific deficits to translational research
    Angus W MacDonald
    Department of Psychology, University of Pittsburgh, USA
    J Abnorm Psychol 116:306-12. 2007
    ..These data suggest that the interpretability gained by including task manipulations to uncover specific deficits can enhance associations between cognitive and genetic levels of analysis...
  7. ncbi request reprint The socio-economic status of communities predicts variation in brain serotonergic responsivity
    Stephen B Manuck
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA 15260, USA
    Psychol Med 35:519-28. 2005
    ..Here we examine whether serotonergic responsivity covaries similarly with the SES of communities, as indexed by US Census data in the same study sample...
  8. ncbi request reprint Irritable assault and variation in the COMT gene
    Janine D Flory
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    Psychiatr Genet 17:344-6. 2007
    ..These findings provide limited support for a role of COMT in modulating aggressive behavior, and are extended to people with personality disorders...
  9. ncbi request reprint Central nervous system serotonergic responsivity and aggressive disposition in men
    Stephen B Manuck
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA, USA
    Physiol Behav 77:705-9. 2002
    ..This finding suggests that association of the MAO-A promoter polymorphism with this behavioral phenotype may be mediated, in part, by allele-specific variation in central serotonergic responsivity...
  10. pmc Parental education is related to C-reactive protein among female middle-aged community volunteers
    Jennifer E Phillips
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Brain Behav Immun 23:677-83. 2009
    ..This association may help explain the increased risk of atherosclerotic cardiovascular morbidity and mortality conferred by low childhood socioeconomic status...
  11. pmc Polymorphic variation in the dopamine D4 receptor predicts delay discounting as a function of childhood socioeconomic status: evidence for differential susceptibility
    Maggie M Sweitzer
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Soc Cogn Affect Neurosci 8:499-508. 2013
    ....
  12. pmc Pergolide treatment of cognitive deficits associated with schizotypal personality disorder: continued evidence of the importance of the dopamine system in the schizophrenia spectrum
    Margaret M McClure
    VA VISN 3 Mental Illness Research, Education, and Clinical Center, Bronx, NY, USA
    Neuropsychopharmacology 35:1356-62. 2010
    ..These results suggest that dopamine agonists may provide benefit for the cognitive abnormalities of schizophrenia spectrum disorders...
  13. ncbi request reprint Serotonergic function in the central nervous system is associated with daily ratings of positive mood
    Janine D Flory
    Department of Psychology, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
    Psychiatry Res 129:11-9. 2004
    ..e., Neuroticism). These results suggest that deficiencies in serotonergic function may reflect the relative absence of positive mood...
  14. ncbi request reprint Neurobiologic function and temperament in subjects with personality disorders
    Vivian Mitropoulou
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA
    CNS Spectr 8:725-30. 2003
    ....
  15. ncbi request reprint Socio-economic status covaries with central nervous system serotonergic responsivity as a function of allelic variation in the serotonin transporter gene-linked polymorphic region
    Stephen B Manuck
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, 506 EH, 4015 O Hara Street, Pittsburgh, PA 15260, USA
    Psychoneuroendocrinology 29:651-68. 2004
    ..We conclude that allelic variation at 5-HTTLPR moderates the influence of social position on CNS serotonergic responsivity...
  16. ncbi request reprint Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groups
    Michael J Minzenberg
    Bronx Veterans Affairs Medical Center, Bronx, New York, 14068, USA
    Psychiatr Genet 16:117-24. 2006
    ..We evaluated the relationship of the COMT genotype with diagnostic status and cognitive performance in schizotypal personality disorder...
  17. pmc Subjective socioeconomic status and presence of the metabolic syndrome in midlife community volunteers
    Stephen B Manuck
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Psychosom Med 72:35-45. 2010
    ....
  18. ncbi request reprint Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteers
    Anna L Marsland
    Behavioral Immunology Laboratory, Department of Psychology, 3943 O Hara Street, Pittsburgh, PA 15260, USA
    Psychosom Med 68:895-903. 2006
    ..The current investigation extends the study of relationships between plasma IL-6 and cognitive performance to healthy middle-aged adults and to an examination of more specific cognitive domains...
  19. ncbi request reprint High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism
    Sarah M Conklin
    Department of Psychology, Allegheny College, 520 North Main Street, Meadville, PA 16335 3902, USA
    Psychosom Med 69:932-4. 2007
    ..Previously we reported that the relative concentrations of omega-3 and omega-6 polyunsaturated fatty acids in serum covary with depressive symptomatology and neuroticism in hypercholesterolemic adults...
  20. pmc Cigarette smoking and measures of impulsivity in a college sample
    Emily C Balevich
    Department of Psychology, Queens College and the Graduate Center of the City University of New York, Flushing, NY 11367, USA
    Subst Abus 34:256-62. 2013
    ..The aim of the current study was to examine the relationship between self-report and behavioral measures of impulsivity and smoking status in college students...
  21. pmc Citalopram intervention for hostility: results of a randomized clinical trial
    Thomas W Kamarck
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    J Consult Clin Psychol 77:174-88. 2009
    ..04). The findings have implications for understanding the central nervous system correlates of hostility, its associations with other psychosocial risk factors for CVD, and, potentially, the design of effective interventions...
  22. doi request reprint Delay discounting and smoking: association with the Fagerström Test for Nicotine Dependence but not cigarettes smoked per day
    Maggie M Sweitzer
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 10:1571-5. 2008
    ..These results suggest that DD among smokers is not simply the result of nicotine exposure, but may be an important marker for dependence, especially urgency to smoke in the morning...
  23. ncbi request reprint The use of biomarkers in the military: from theory to practice
    Rachel Yehuda
    Department of Psychiatry, James J Peters Veterans Affairs Medical Center, Bronx, NY, United States Department of Psychiatry and Neuroscience, Mount Sinai School of Medicine, New York, NY, United States Electronic address
    Psychoneuroendocrinology 38:1912-22. 2013
    ....
  24. pmc Hostile mood and social strain during daily life: a test of the transactional model
    Elizabeth J Vella
    Department of Psychology, University of Southern Maine, Portland, ME 04103, USA
    Ann Behav Med 44:341-52. 2012
    ..Hostility is a multidimensional construct related to cardiovascular (CV) disease risk. Daily hostile mood and social interactions may precipitate stress-related CV responses in hostile individuals...
  25. doi request reprint Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD
    Rachel Yehuda
    Department of Psychiatry, James J Peters Veterans Affairs Medical Center, 526 OOMH, 130 W Kingsbridge Rd, Bronx, NY, USA
    Psychopharmacology (Berl) 212:405-17. 2010
    ..Given similarities between neuroendocrine aspects of PTSD and ELS, such as in reduced cortisol signaling and glucocorticoid receptor (GR) responsiveness, some aspects of the biology of PTSD may reflect biological correlates of risk...
  26. pmc The role of genes in defining a molecular biology of PTSD
    Rachel Yehuda
    Department of Psychiatry, James J Peters Veterans Affairs Medical Center, Bronx, New York, USA
    Dis Markers 30:67-76. 2011
    ..Since inherited genetic variation may also influence the extent of epigenetic or gene expression changes resulting from the environment, such studies should optimally be followed up by studies of genotype...
  27. ncbi request reprint Retest reliability of prolactin response to dl-fenfluramine challenge in adults
    Janine D Flory
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuropsychopharmacology 26:269-72. 2002
    ..57 for PRL "area under the curve," p <.0001). These findings are consistent with speculation that variability in indices of central serotonergic function reflects a temporally stable dimension of individual differences...
  28. ncbi request reprint A convergent-divergent approach to context processing, general intellectual functioning, and the genetic liability to schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    Neuropsychology 19:814-21. 2005
    ....
  29. pmc The BDNF Val66Met polymorphism does not moderate the effect of self-reported physical activity on depressive symptoms in midlife
    Swathi Gujral
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA
    Psychiatry Res 218:93-7. 2014
    ..01). BDNF genotype did not moderate the effect of physical activity on depressive symptoms (p=0.94). In midlife, the BDNF Val66Met polymorphism neither attenuates nor magnifies the effect of physical activity on depressive symptoms. ..
  30. ncbi request reprint Differentiating biological correlates of risk, PTSD, and resilience following trauma exposure
    Rachel Yehuda
    Department of Psychiatry, Mount Sinai School of Medicine, New York, and Department of Psychiatry, Bronx VAMC, Bronx, NY 10468, USA
    J Trauma Stress 20:435-47. 2007
    ....
  31. ncbi request reprint The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteers
    Matthew F Muldoon
    Division of Clinical Pharmacology, Departments of Medicine and Epidemiology, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
    J Clin Endocrinol Metab 91:718-21. 2006
    ..The pathobiology of the metabolic syndrome remains unclear. The central nervous system is likely to be involved via regulation of eating, physical activity, blood pressure, and metabolism...
  32. ncbi request reprint A comparison of d, l-fenfluramine and citalopram challenges in healthy adults
    Janine D Flory
    Behavioral Physiology Laboratory 506 OEH, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 174:376-80. 2004
    ..49, P's< or =0.02). The magnitude of the correlations is notable given the length of time between challenges. The results support the use of citalopram as an alternate neuroendocrine challenge to index CNS serotonergic responsivity...
  33. ncbi request reprint Lower central serotonergic responsivity is associated with preclinical carotid artery atherosclerosis
    Matthew F Muldoon
    Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Stroke 38:2228-33. 2007
    ..This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...
  34. ncbi request reprint Dispositional impulsivity in normal and abnormal samples
    Janine D Flory
    Department of Psychiatry, Box 1230, One Gustave Levy Place, Mount Sinai School of Medicine, New York, NY 10029, United States
    J Psychiatr Res 40:438-47. 2006
    ..Results from these analyses also lend support to a large body of work that demonstrates that normal and abnormal personality features are related...
  35. ncbi request reprint Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivity
    Matthew F Muldoon
    Divisions of Clinical Pharmacology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    J Clin Endocrinol Metab 89:266-71. 2004
    ..These findings reveal a heretofore unrecognized association between reduced central serotonergic responsivity and the metabolic syndrome...

Research Grants2

  1. Endophenotypes for Borderline Personality Disorder
    Janine Flory; Fiscal Year: 2006
    ..abstract_text> ..