Abdeslem El Idrissi

Summary

Affiliation: City University of New York
Country: USA

Publications

  1. ncbi Taurine regulates mitochondrial calcium homeostasis
    Abdeslem El Idrissi
    New York State Institute for Basic Research in Developmental Disabilities and The Center for Developmental Neuroscience, The City University of New York, Staten Island, NY 10314, USA
    Adv Exp Med Biol 526:527-36. 2003
  2. ncbi Effects of taurine on anxiety-like and locomotor behavior of mice
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, NewYork, USA
    Adv Exp Med Biol 643:207-15. 2009
  3. ncbi Taurine supplementation and pancreatic remodeling
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, NewYork, USA
    Adv Exp Med Biol 643:353-8. 2009
  4. ncbi Functional implication of taurine in aging
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, NewYork, USA
    Adv Exp Med Biol 643:199-206. 2009
  5. ncbi Taurine improves congestive functions in a mouse model of fragile X syndrome
    Abdeslem El Idrissi
    Biology Neuroscience, College of Staten Island, City University of New York Graduate School, New York, USA
    Adv Exp Med Biol 643:191-8. 2009
  6. ncbi Selective resistance of taurine-fed mice to isoniazide-potentiated seizures: in vivo functional test for the activity of glutamic acid decarboxylase
    A El Idrissi
    Department of Biology, College of Staten Island, 2800 Victory Boulevard, Staten Island, NY 10314, USA
    Neuroscience 156:693-9. 2008
  7. ncbi Taurine improves learning and retention in aged mice
    Abdeslem El Idrissi
    Department of Biology, The Center for Developmental Neuroscience, College of Staten Island, 2800 Victory Blvd, 6S 316 Staten Island, NY 10314, United States
    Neurosci Lett 436:19-22. 2008
  8. ncbi Taurine increases mitochondrial buffering of calcium: role in neuroprotection
    A El Idrissi
    Department of Biology and Center for Developmental Neuroscience, College of Staten Island of the City University of New York, New York 10314, USA
    Amino Acids 34:321-8. 2008
  9. ncbi Neuroendocrine alterations in the fragile X mouse
    Abdeslem El Idrissi
    Department of Biology, College of Staten Island, Staten Island, NY, USA
    Results Probl Cell Differ 54:201-21. 2012
  10. ncbi Neuro-endocrine basis for altered plasma glucose homeostasis in the Fragile X mouse
    Abdeslem El Idrissi
    Department of Biology, College of Staten Island, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA
    J Biomed Sci 17:S8. 2010

Collaborators

  • William J L'Amoreaux
  • Narayan Ramakrishna
  • Efrain C Azmitia
  • Zaghloul Ahmed
  • Lorenz S Neuwirth
  • Chang Hui Shen
  • Andrew Hong
  • Sudarshana Purkayastha
  • Natalia Levinskaya
  • Xin Yan
  • Isma Butt
  • Eugene Lempert
  • Nicholas P Volpe
  • Baishali Kanjilal
  • Probal Banerjee
  • Yang Ke
  • Souleymane Diallo
  • Lorenz Neuwirth
  • Andrzej Wieraszko
  • Aiying Zhang
  • Joseph Del Rosario Inigo
  • Jason Ford
  • Ekkhart Trenkner

Detail Information

Publications24

  1. ncbi Taurine regulates mitochondrial calcium homeostasis
    Abdeslem El Idrissi
    New York State Institute for Basic Research in Developmental Disabilities and The Center for Developmental Neuroscience, The City University of New York, Staten Island, NY 10314, USA
    Adv Exp Med Biol 526:527-36. 2003
    ..We conclude that taurine prevents or reduces glutamate excitotoxicity through both the enhancement of mitochondrial function and the regulation of intracellular (cytoplasmic and mitochondrial) calcium homeostasis...
  2. ncbi Effects of taurine on anxiety-like and locomotor behavior of mice
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, NewYork, USA
    Adv Exp Med Biol 643:207-15. 2009
    ..Second, taurine when injected acutely had opposite effects than when administered chronically...
  3. ncbi Taurine supplementation and pancreatic remodeling
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, NewYork, USA
    Adv Exp Med Biol 643:353-8. 2009
    ....
  4. ncbi Functional implication of taurine in aging
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, NewYork, USA
    Adv Exp Med Biol 643:199-206. 2009
    ..Taurine might help forestall the age-related decline in cognitive functions through interaction with the GABAergic system...
  5. ncbi Taurine improves congestive functions in a mouse model of fragile X syndrome
    Abdeslem El Idrissi
    Biology Neuroscience, College of Staten Island, City University of New York Graduate School, New York, USA
    Adv Exp Med Biol 643:191-8. 2009
    ....
  6. ncbi Selective resistance of taurine-fed mice to isoniazide-potentiated seizures: in vivo functional test for the activity of glutamic acid decarboxylase
    A El Idrissi
    Department of Biology, College of Staten Island, 2800 Victory Boulevard, Staten Island, NY 10314, USA
    Neuroscience 156:693-9. 2008
    ..Furthermore, this pharmacological manipulation can be used to determine the level of GAD activity in other model systems that show alterations in GAD expression...
  7. ncbi Taurine improves learning and retention in aged mice
    Abdeslem El Idrissi
    Department of Biology, The Center for Developmental Neuroscience, College of Staten Island, 2800 Victory Blvd, 6S 316 Staten Island, NY 10314, United States
    Neurosci Lett 436:19-22. 2008
    ..Taurine might help forestall the age-related decline in cognitive functions through alterations of the GABAergic system...
  8. ncbi Taurine increases mitochondrial buffering of calcium: role in neuroprotection
    A El Idrissi
    Department of Biology and Center for Developmental Neuroscience, College of Staten Island of the City University of New York, New York 10314, USA
    Amino Acids 34:321-8. 2008
    ..Taurine may serve as an endogenous neuroprotective molecule against brain insults...
  9. ncbi Neuroendocrine alterations in the fragile X mouse
    Abdeslem El Idrissi
    Department of Biology, College of Staten Island, Staten Island, NY, USA
    Results Probl Cell Differ 54:201-21. 2012
    ....
  10. ncbi Neuro-endocrine basis for altered plasma glucose homeostasis in the Fragile X mouse
    Abdeslem El Idrissi
    Department of Biology, College of Staten Island, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA
    J Biomed Sci 17:S8. 2010
    ..Since there are considerable similarities in the GABAergic system in the brain and pancreas, we evaluated the protective role of taurine in pancreatic islet development in both wild type (WT) and fragile X mice (KO)...
  11. ncbi Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse
    Abdeslem El Idrissi
    Department of Human Genetics, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Rd, Staten Island, NY 10314, USA
    Neurosci Lett 377:141-6. 2005
    ..These alterations may also be relevant to the seizures and the abnormal behaviors in the human syndrome...
  12. ncbi Taurine and brain excitability
    Abdeslem El Idrissi
    Department of Biology and Center for Development, College of Staten Island, The City University of New York, Staten Island, NY 10314, USA
    Adv Exp Med Biol 583:315-22. 2006
  13. ncbi Downregulation of GABA(A) β subunits is transcriptionally controlled by Fmr1p
    Andrew Hong
    Department of Biology, College of Staten Island, City University of New York, 2800 Victory Blvd, Staten Island, NY 10314, USA
    J Mol Neurosci 46:272-5. 2012
    ..This finding may help to establish the link between the transcriptional profile of the GABAergic inhibitory system and the development of fragile X mental retardation syndrome...
  14. ncbi Increased GAD-positive neurons in the cortex of taurine-fed mice
    Natalia Levinskaya
    Department of Biology and Center for Development, College of Staten Island, The City University of New York, Staten Island, NY 10314, USA
    Adv Exp Med Biol 583:411-7. 2006
  15. ncbi Clozapine functions through the prefrontal cortex serotonin 1A receptor to heighten neuronal activity via calmodulin kinase II-NMDA receptor interactions
    Sudarshana Purkayastha
    CSI IBR Center for Developmental Neuroscience, The College of Staten Island, Staten Island, New York 10314, USA
    J Neurochem 120:396-407. 2012
    ..In summary, Clz functions in the PFC by orchestrating a synergism among 5-HT(1A)-R, CaMKII, and NMDA-R, which augments excitability in the PFC neurons of layers II/III...
  16. ncbi Taurine as a modulator of excitatory and inhibitory neurotransmission
    Abdeslem El Idrissi
    New York State Institute for Basic Research in Developmental Disabilities and The Center for Developmental Neuroscience at The City University of New York, Staten Island, New York 10314, USA
    Neurochem Res 29:189-97. 2004
    ..Furthermore, as a consequence of calcium regulation, taurine counteracted glutamate-induced mitochondrial damage and cell death...
  17. ncbi Changes in gene expression at inhibitory synapses in response to taurine treatment
    Chang Hui Shen
    Department of Biology, College of Staten Island, Staten Island, NY 10314, USA
    Adv Exp Med Biol 775:187-94. 2013
    ..Taurine might help forestall the age-related decline in cognitive functions through interaction with the GABAergic system...
  18. ncbi Taurine regulation of blood pressure and vasoactivity
    Abdeslem El Idrissi
    Department of Biology, City University of New York Graduate School, Staten Island, NY 10314, USA
    Adv Exp Med Biol 775:407-25. 2013
    ..However, our data indicate that supplementation of taurine to females caused a significant increase in blood pressure. The effect of taurine supplementation on hypertensive rats remains to be seen...
  19. ncbi Taurine regulation of short term synaptic plasticity in fragile X mice
    Abdeslem El Idrissi
    Department of Biology, College of Staten Island, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA
    J Biomed Sci 17:S15. 2010
    ....
  20. ncbi Pharmacological characterization of GABAA receptors in taurine-fed mice
    William J L'Amoreaux
    Department of Biology, College of Staten Island, 2800 Victory Blvd, Staten Island, NY 10314, USA
    J Biomed Sci 17:S14. 2010
    ..These are the same subunits to which GABA and presumably taurine binds...
  21. ncbi Taurine regulates insulin release from pancreatic beta cell lines
    William J L'Amoreaux
    Department of Biology, College of Staten Island, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA
    J Biomed Sci 17:S11. 2010
    ..If taurine uptake does alter beta-cell current, it might have an effect on exocytosis of cytoplasmic vesicle. We wished to test the effect of taurine on regulating release of insulin from the pancreatic beta-cell...
  22. ncbi Taurine effects on emotional learning and memory in aged mice: neurochemical alterations and differentiation in auditory cued fear and context conditioning
    Lorenz S Neuwirth
    Department of Biology, Neuroscience College of Staten Island, Staten Island, NY 10314, USA
    Adv Exp Med Biol 775:195-214. 2013
    ..Our findings suggest that taurine causes not only varied phenotypic profiles of emotional fear learning, but are further complicated by the inability to associate cues with aversive stimuli due to potential auditory sensory overloading...
  23. ncbi Regulation of α-synuclein expression in Down syndrome
    Narayan Ramakrishna
    Department Molecular Biology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York 10314, USA
    J Neurosci Res 90:1589-96. 2012
    ..These findings reveal potential target sites for intervention in the treatment of DS pathology...
  24. ncbi Prevention of epileptic seizures by taurine
    Abdeslem El Idrissi
    New York State Institute for Basic Research in Developmental Disabilities and The Center for Developmental Neuroscience, The City University of New York, Staten Island, NY 10314, USA
    Adv Exp Med Biol 526:515-25. 2003
    ..Therefore, taurine is potentially capable of treating seizure-associated brain damage...