Research Topics
Genomes and GenesSpecies | Jessica G WooSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
Specific infant feeding practices do not consistently explain variation in anthropometry at age 1 year in urban United States, Mexico, and China cohortsJessica G Woo
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Nutr 143:166-74. 2013..Overall, across these urban, international, breast-fed cohorts, differences in specific feeding practices did not explain the significant variation in anthropometry...- Quantitative criteria for improving performance of buccal DNA for high-throughput genetic analysisJessica G Woo
Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
BMC Genet 13:75. 2012..phs.wfubmc.edu/public/index.cfm)... - Human milk adiponectin affects infant weight trajectory during the second year of lifeJessica G Woo
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
J Pediatr Gastroenterol Nutr 54:532-9. 2012..We examined infant weight gain in the second year of life after exposure to high or low levels of mother's milk APN... 
Using body mass index Z-score among severely obese adolescents: a cautionary noteJessica G Woo
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Int J Pediatr Obes 4:405-10. 2009..A new supplemental BMI reference may be needed specifically for severely obese adolescents to improve measurement and evaluation of treatment success in this group...- Obesity identified by discharge ICD-9 codes underestimates the true prevalence of obesity in hospitalized childrenJessica G Woo
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Pediatr 154:327-31. 2009..To define inpatient care of obese children with or without an obesity diagnosis... - Breastfeeding helps explain racial and socioeconomic status disparities in adolescent adiposityJessica G Woo
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, MLC 5041, Cincinnati, OH 45229 3039, USA
Pediatrics 121:e458-65. 2008..Racial and socioeconomic status differences in breastfeeding behavior have also been noted. In this study, we formally test whether breastfeeding mediates the relationship between race and socioeconomic status with adolescent adiposity... - Quality assessment of buccal versus blood genomic DNA using the Affymetrix 500 K GeneChipJessica G Woo
University of Cincinnati College of Medicine, 321 Albert Sabin Way, Cincinnati, OH 45267, USA
BMC Genet 8:79. 2007..We sought to describe the genomic DNA yield and concordance between stored buccal brushes and blood samples from the same individuals in the context of Affymetrix 500 K Human GeneChip genotyping... 
Adolescent sex differences in adiponectin are conditional on pubertal development and adiposityJessica G Woo
Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
Obes Res 13:2095-101. 2005..In this study, we hypothesized that sex differences in adiponectin would develop during puberty and would be influenced by level of adiposity...- Interactions between noncontiguous haplotypes in the adiponectin gene ACDC are associated with plasma adiponectinJessica G Woo
Cincinnati Children s Hospital Medical Center, OH 45229, USA
Diabetes 55:523-9. 2006..Interactions between noncontiguous ACDC haplotypes strongly influence adiponectin levels, suggesting nonadditive and potentially cis relationships between these regions... - Human milk adiponectin is associated with infant growth in two independent cohortsJessica G Woo
Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3039, USA
Breastfeed Med 4:101-9. 2009..We have previously shown that adiponectin is present in human milk. This study determined whether higher milk adiponectin is associated with infant growth and investigated milk adiponectin's oligomeric form... - Adiponectin is present in human milk and is associated with maternal factorsLisa J Martin
Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Am J Clin Nutr 83:1106-11. 2006..If present in milk, adiponectin would be a promising candidate for influencing infant development, given its metabolic functions... - Adiponectin receptor 1 variants associated with lower insulin resistance in African AmericansNancy A Crimmins
Department of Pediatrics, MLC 7012, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
Obesity (Silver Spring) 15:1903-7. 2007..Our findings suggest not only that ADIPOR1 variants influence insulin resistance in the presence of adiposity, but also that these variants and haplotypes are protective in African Americans... - Stability of adolescent body mass index during three years of follow-upNancy A Crimmins
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr 151:383-7. 2007..A 4-year longitudinal study was conducted to determine the prevalence of overweight, detect shifts in body mass index (BMI) distribution, and determine which adolescents were at risk for pathologic weight gain... - Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypassCatherine D Krawczeski
The Heart Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
J Am Coll Cardiol 58:2301-9. 2011.... - Neutrophil gelatinase-associated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypassCatherine D Krawczeski
Heart Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
J Pediatr 158:1009-1015.e1. 2011..To investigate neutrophil gelatinase-associated lipocalin (NGAL) as an early acute kidney injury (AKI) biomarker after neonatal and pediatric cardiopulmonary bypass (CPB)... - β-cell dysfunction in adolescents and adults with newly diagnosed type 2 diabetes mellitusDeborah A Elder
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Pediatr 160:904-10. 2012..To compare β-cell function in adolescents and adults with newly diagnosed type 2 diabetes (T2DM)... - Role of carbohydrate modification in weight management among obese children: a randomized clinical trialShelley Kirk
Center for Better Health and Nutrition, The Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Pediatr 161:320-7.e1. 2012..To compare the effectiveness and safety of carbohydrate (CHO)-modified diets with a standard portion-controlled (PC) diet in obese children... - Shared genetic contributions of fruit and vegetable consumption with BMI in families 20 y after sharing a householdLisa J Martin
Division of Human Genetics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Am J Clin Nutr 94:1138-43. 2011..Interestingly, diet also has a genetic basis. Thus, we hypothesized that the genetic underpinnings of diet may partially overlap with the genetics of obesity... - Evidence of shared genetic effects between pre- and postobesity epidemic BMI levelsLisa J Martin
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Obesity (Silver Spring) 18:1378-82. 2010..Furthermore, shared genetic effects survive the period of the transition from adolescence to adulthood... - The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposityLisa J Martin
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
J Clin Endocrinol Metab 90:4255-9. 2005..Because adiponectin is secreted by adipocytes, it may also act locally to counteract insulin resistance and dyslipidemia worsened by inflammation... - Serum cystatin C is an early predictive biomarker of acute kidney injury after pediatric cardiopulmonary bypassCatherine D Krawczeski
The Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Clin J Am Soc Nephrol 5:1552-7. 2010..Biomarkers that are sensitive and rapidly measurable could allow early intervention and improve patient outcomes. We investigated the value of serum cystatin C as an early biomarker for AKI after pediatric CPB... - Impaired beta-cell sensitivity to glucose and maximal insulin secretory capacity in adolescents with type 2 diabetesDeborah A Elder
Cincinnati Children s Hospital Medical Center, Department of Pediatrics, Division of Endocrinology, Cincinnati, OH 45229, USA
Pediatr Diabetes 11:314-21. 2010..In adolescents with T2DM, there is some evidence that beta-cell dysfunction may be less severe. Our objective was to determine beta-cell sensitivity to glucose and maximal insulin secretory capacity (AIR(max)) in teenagers with T2DM... - Multiple testing in the genomics era: findings from Genetic Analysis Workshop 15, Group 15Lisa J Martin
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Genet Epidemiol 31:S124-31. 2007..We show that while each approach may have certain advantages, adequate error control is largely dependent upon the question under consideration and often requires the use of multiple analytic strategies... - Improving the signal-to-noise ratio in genome-wide association studiesLisa J Martin
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Genet Epidemiol 33:S29-32. 2009..This article reviews how Genetic Analysis Workshop 16 Group 5 investigators proposed to adjust for multiple tests while simultaneously using information about the structure of the genome to improve the detection of true positives... - The effect of minor allele frequency on the likelihood of obtaining false positivesMeredith E Tabangin
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Mail Code 5041, Cincinnati, Ohio 45229, USA
BMC Proc 3:S41. 2009..1]) than MAF = 25% and 50%. Similar results were seen at the other alpha values.These results suggest that removal of low MAF SNPs from analysis due to concerns about inflated false-positive results may not be appropriate... - Risk factors for cardiovascular disease and type 2 diabetes retained from childhood to adulthood predict adult outcomes: the Princeton LRC Follow-up StudyJohn A Morrison
From the Cholesterol and Metabolism Center, Jewish Hospital of Cincinnati, Cincinnati, USA
Int J Pediatr Endocrinol 2012:6. 2012..abstract:.. - Dietary assessment of adolescents undergoing laparoscopic Roux-en-Y gastric bypass surgery: macro- and micronutrient, fiber, and supplement intakeRenee M Jeffreys
Division of Pediatric and Thoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Surg Obes Relat Dis 8:331-6. 2012..Our objective was to assess the 1-year change in the dietary composition of adolescents undergoing bariatric surgery at a tertiary care children's hospital... - Comparison of false-discovery rate for genome-wide and fine mapping regionsMeredith E Tabangin
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 5041, Cincinnati, Ohio 45229 3039, USA
BMC Proc 1:S148. 2007..However, in fine mapping, all tested methods performed poorly, producing a high proportion of significant results. Thus, caution should be used when employing FDR for fine mapping... - Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytesEric R Hugo
Department of Cell and Cancer Biology, University of Cincinnati, 3125 Eden Avenue, Cincinnati, OH 45267, USA
Environ Health Perspect 116:1642-7. 2008..Thus, any factor that suppresses adiponectin release could lead to insulin resistance and increased susceptibility to obesity-associated diseases... - The -159 C-->T polymorphism of CD14 is associated with nonatopic asthma and food allergyJessica G Woo
Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincinnati Medical Center, Ohio, USA
J Allergy Clin Immunol 112:438-44. 2003..CD14, the receptor for LPS, plays an important role in innate immunity. A polymorphism in the promotor for CD14, -159 C-->T, has been implicated in atopy...
Research Grants
- Adiponectin in Human Milk and Infant Serum in Relation to Early AdiposityJessica Woo; Fiscal Year: 2007....