I Ching Wang

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium
    I Ching Wang
    Divisions of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, USA
    Mol Cell Biol 32:3838-50. 2012
  2. pmc Increased expression of FoxM1 transcription factor in respiratory epithelium inhibits lung sacculation and causes Clara cell hyperplasia
    I Ching Wang
    Division of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Dev Biol 347:301-14. 2010
  3. pmc Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition
    David Balli
    Department of Pediatrics, Division of Pulmonary Biology, The Perinatal Institute, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    EMBO J 32:231-44. 2013
  4. pmc Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways
    Vladimir Ustiyan
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Dev Biol 370:198-212. 2012
  5. pmc Forkhead Box m1 transcription factor is required for perinatal lung function
    Tanya V Kalin
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 105:19330-5. 2008
  6. pmc Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagus
    Vladimir Ustiyan
    Divisions of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Dev Biol 336:266-79. 2009
  7. pmc Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis
    I Ching Wang
    Division of Pulmonary Biology and the Perinatal Institute, Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, USA
    PLoS ONE 4:e6609. 2009
  8. pmc Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development
    Craig Bolte
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e22217. 2011

Collaborators

Detail Information

Publications8

  1. pmc Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium
    I Ching Wang
    Divisions of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, USA
    Mol Cell Biol 32:3838-50. 2012
    ..Foxm1 is required for Kras signaling in distal lung epithelium and provides a mechanism integrating Kras and canonical Wnt/β-catenin signaling during lung development...
  2. pmc Increased expression of FoxM1 transcription factor in respiratory epithelium inhibits lung sacculation and causes Clara cell hyperplasia
    I Ching Wang
    Division of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Dev Biol 347:301-14. 2010
    ....
  3. pmc Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition
    David Balli
    Department of Pediatrics, Division of Pulmonary Biology, The Perinatal Institute, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    EMBO J 32:231-44. 2013
    ..Foxm1 is required for radiation-induced pulmonary fibrosis by enhancing the expression of genes critical for lung inflammation and EMT...
  4. pmc Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways
    Vladimir Ustiyan
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Dev Biol 370:198-212. 2012
    ..In co-transfection experiments, Foxm1 directly bound to and induced transcriptional activity of Scgb1a1 and Sox2 promoters. Foxm1 is required for differentiation and maintenance of epithelial cells lining conducting airways...
  5. pmc Forkhead Box m1 transcription factor is required for perinatal lung function
    Tanya V Kalin
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 105:19330-5. 2008
    ..Foxm1 is critical for surfactant homeostasis and lung maturation before birth and is required for adaptation to air breathing...
  6. pmc Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagus
    Vladimir Ustiyan
    Divisions of Pulmonary Biology, Perinatal Institute of the Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Dev Biol 336:266-79. 2009
    ..Foxm1 is critical for proliferation of smooth muscle cells and is required for proper embryonic development of blood vessels and esophagus...
  7. pmc Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis
    I Ching Wang
    Division of Pulmonary Biology and the Perinatal Institute, Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, USA
    PLoS ONE 4:e6609. 2009
    ..Expression of Foxm1 in respiratory epithelial cells is critical for lung cancer formation and TOPO-2alpha expression in vivo, suggesting that Foxm1 is a promising target for anti-tumor therapy...
  8. pmc Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development
    Craig Bolte
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e22217. 2011
    ..Our results indicate that Foxm1 expression in cardiomyocytes is critical for proper heart development and required for cardiomyocyte proliferation and myocardial growth...