Genomes and Genes
Brian M Varisco
Affiliation: Cincinnati Children's Hospital Medical Center
- The pharmacology of acute lung injury in sepsisBrian Michael Varisco
Division of Critical Care, Cincinnati Children s Hospital Medical Center, MLC 2005, Cincinnati, OH 45229 3039, USA
Adv Pharmacol Sci 2011:254619. 2011..In this paper, we discuss the epidemiology and pathophysiology of ALI, commonly employed pharmacologic and nonpharmacologic treatments, and innovative therapeutic modalities that will likely be the focus of future trials...
- JNK suppresses pulmonary fibroblast elastogenesis during alveolar developmentSheng Liu
Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, USA
Respir Res 15:34. 2014..JNK suppress elastin synthesis in the aorta and is important in a host of developmental processes. We sought to determine whether JNK suppresses pulmonary fibroblast elastogenesis during lung development...
- Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lungBrian M Varisco
Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Am J Respir Cell Mol Biol 46:765-72. 2012..Thy-1 is important in the regulation of lipofibroblast differentiation in the developing lung...
- Wntless is required for peripheral lung differentiation and pulmonary vascular developmentBridget Cornett
The Perinatal Institute Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Cincinnati Children s Hospital Medical Center Research Foundation, Cincinnati, OH 45229, USA
Dev Biol 379:38-52. 2013..These studies provide a new framework for understanding the molecular mechanisms underlying normal pulmonary vasculature formation and the dysmorphic pulmonary vasculature development associated with congenital lung disease...