Patrick D Solan

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Liver X receptor α activation with the synthetic ligand T0901317 reduces lung injury and inflammation after hemorrhage and resuscitation via inhibition of the nuclear factor κB pathway
    Patrick D Solan
    Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Shock 35:367-74. 2011
  2. pmc Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis
    Siarhei Slinko
    Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children s Hospital Medical Center and Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, Ohio
    Shock 41:292-300. 2014

Collaborators

  • Siarhei Slinko
  • Giovanna Piraino
  • Patrick Lahni
  • John R Ledford
  • MICHAEL O'CONNOR
  • Paul W Hake
  • Hector R Wong
  • Basilia Zingarelli

Detail Information

Publications2

  1. pmc Liver X receptor α activation with the synthetic ligand T0901317 reduces lung injury and inflammation after hemorrhage and resuscitation via inhibition of the nuclear factor κB pathway
    Patrick D Solan
    Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Shock 35:367-74. 2011
    ..Thus, our data suggest that LXRα is an important modulator of the inflammatory response and lung injury after severe hemorrhagic shock, likely through the inhibition of the nuclear factor κB pathway...
  2. pmc Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis
    Siarhei Slinko
    Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children s Hospital Medical Center and Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, Ohio
    Shock 41:292-300. 2014
    ..Our data demonstrate that short-term zinc prophylaxis before the infectious insult is a requisite for the anti-inflammatory properties of C-peptide by facilitating modulation of inflammatory pathways...