Research Topics
| Vincent J SchmithorstSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
Development of effective connectivity for narrative comprehension in childrenVincent J Schmithorst
Pediatric Neuroimaging Research Consortium, Imaging Research Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
Neuroreport 18:1411-5. 2007..The results demonstrate the feasibility of performing multi subject multivariate autoregressive modeling analyses to investigate effective connectivity in the absence of an a priori model...- Separate cortical networks involved in music perception: preliminary functional MRI evidence for modularity of music processingVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Avenue, ML 5031, Cincinnati, OH 45229, USA
Neuroimage 25:444-51. 2005..The results suggest that, while some networks overlap with ones used for language processing, music processing may involve its own domain-specific processing subsystems... - Empirical validation of the triple-code model of numerical processing for complex math operations using functional MRI and group Independent Component Analysis of the mental addition and subtraction of fractionsVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Neuroimage 22:1414-20. 2004.... - Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI studyVincent J Schmithorst
Imaging Research Center, Cincinnati Children s Hospital Medical Center, OH 45229, USA
Hum Brain Mapp 26:139-47. 2005..The results are consistent with the hypothesis that regionally specific increased fiber organization is a mechanism responsible for the normal development of white matter tracts... - Higher-order contrast functions improve performance of independent component analysis of fMRI dataVincent J Schmithorst
Pediatric Neuroimaging Research Consortium, Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Magn Reson Imaging 29:242-9. 2009.... - Sex differences in the development of neuroanatomical functional connectivity underlying intelligence found using Bayesian connectivity analysisVincent J Schmithorst
Pediatric Brain Imaging Research Program, Imaging Research Center, Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Neuroimage 35:406-19. 2007..Our results demonstrate a sexual dimorphism in the relationship of functional connectivity to intelligence in children and an increasing reliance on inter-hemispheric connectivity in girls with age... - Object identification and lexical/semantic access in children: a functional magnetic resonance imaging study of word-picture matchingVincent J Schmithorst
Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Hum Brain Mapp 28:1060-74. 2007..The results corroborate the continued development of the ventral visual pathway throughout the developmental period... - Cognitive modules utilized for narrative comprehension in children: a functional magnetic resonance imaging studyVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
Neuroimage 29:254-66. 2006..The results are discussed in light of recent hypotheses involving the functional segregation of Wernicke's area and the specific role of the mid-superior temporal gyrus in speech comprehension... - White matter development during adolescence as shown by diffusion MRIVincent J Schmithorst
Pediatric Neuroimaging Research Consortium, Dept of Radiology, Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Brain Cogn 72:16-25. 2010..There is a need for more research to further elucidate the development of white matter and its relation to cognitive function during this critical developmental period... - Diffusion tensor imaging reveals white matter microstructure correlations with auditory processing abilityVincent J Schmithorst
Department of Radiology, Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Ear Hear 32:156-67. 2011..In addition, we hypothesize that the regions displaying correlations will vary according to the task because each task uses a different set of skills... - Functional MRI evidence for disparate developmental processes underlying intelligence in boys and girlsVincent J Schmithorst
Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Neuroimage 31:1366-79. 2006..Our results provide evidence for disparate neuroanatomical trajectories underlying intelligence in boys and girls... - Cortical reorganization in children with unilateral sensorineural hearing lossVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Neuroreport 16:463-7. 2005..The results provide preliminary evidence of disparate neural circuitry supporting auditory processing in participants with left and right USNHL... - fMRI shows atypical language lateralization in pediatric epilepsy patientsWeihong Yuan
Cincinnati Children's Hospital Medical Center, Imaging Research Center, Cincinnati, Ohio 45229, USA
Epilepsia 47:593-600. 2006..234, p<0.05). CONCLUSIONS: This study shows that epilepsy during childhood is associated with neuroplasticity and reorganization of language function... - The effect of musical training on music processing: a functional magnetic resonance imaging study in humansVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, Mail Location 5031, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Neurosci Lett 348:65-8. 2003..The inferior parietal lobules were recruited only by musicians for both tasks. We conclude that musical training results in the recruitment of different neural networks for these aspects of music processing... - Left-handedness and language lateralization in childrenJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, USA
Brain Res 1433:85-97. 2012..e., independent of handedness) indicating the presence of similar mechanisms for language lateralization in left- and right-handed children... - Functional MRI of language lateralization during development in childrenScott K Holland
Pediatric Neuroimaging Research Consortium, Cincinnati Children s Research Foundation, University of Cincinnati, OH 45229, USA
Int J Audiol 46:533-51. 2007..This review emphasizes the importance of considering age and child development in neuroimaging studies of language... - Language networks in children: evidence from functional MRI studiesJennifer Vannest
Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Research Foundation and Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 5033, USA
AJR Am J Roentgenol 192:1190-6. 2009..Multiple fMRI tasks for pediatric patients characterize functional brain reorganization that may accompany language deficits... - Developmental differences in white matter architecture between boys and girlsVincent J Schmithorst
Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Hum Brain Mapp 29:696-710. 2008..The results also may have implications for the study of the relationship of brain architecture with intelligence... - Functional magnetic resonance imaging of cognitive processing in young adults with Down syndromeLisa M Jacola
Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
Am J Intellect Dev Disabil 116:344-59. 2011..These findings supported the authors' hypothesis that persons with Down syndrome demonstrate atypical neural activation compared with typically developing individuals matched for chronological age... - Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in LymphangioleiomyomatosisVincent J Schmithorst
Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
AJR Am J Roentgenol 192:1037-44. 2009..The purpose of our study was to develop a new method for quantifying the severity of cystic lung disease using chest CT and to evaluate this method in patients with lymphangioleiomyomatosis (LAM)... - A group independent component analysis of covert verb generation in children: a functional magnetic resonance imaging studyPrasanna Karunanayaka
Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, and Department of Neurology and Center for Imaging Research, University of Cincinnati, Cincinnati, OH 45229, USA
Neuroimage 51:472-87. 2010..In this context, group ICA of fMRI data from our large sample of children aged 5-18 years provides strong evidence in support of the regionally weighted model for cognitive neurodevelopment of language networks... - fMRI study of language lateralization in children and adultsJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0525, USA
Hum Brain Mapp 27:202-12. 2006..Our findings indicate that language lateralization to the dominant hemisphere increases between the ages 5 and 20 years, plateaus between 20 and 25 years, and slowly decreases between 25 and 70 years... - High-resolution functional MRI at 3T in healthy and epilepsy subjects: hippocampal activation with picture encoding taskJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH, USA
Epilepsy Behav 5:244-52. 2004..Furthermore, these results suggest that a larger study to test the utility of high-resolution fMRI in epilepsy presurgical evaluation is needed... - Comparison of fMRI data from passive listening and active-response story processing tasks in childrenJennifer J Vannest
Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, USA
J Magn Reson Imaging 29:971-6. 2009..We compare a passive listening (PL) story paradigm to an active-response (AR) version including online performance monitoring and a sparse acquisition technique... - Sound blending in the brain: a functional magnetic resonance imaging investigationC Y Peter Chiu
Department of Psychology, University of Cincinnati, Cincinnati, Ohio, USA
Neuroreport 16:883-6. 2005..Our findings are consistent with prior studies ascribing a role of general sequencing, motor and articulatory programming, and vocal or subvocal articulatory rehearsal to this brain region... - Age-related connectivity changes in fMRI data from children listening to storiesPrasanna R Karunanayaka
Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
Neuroimage 34:349-60. 2007..The classical Wernicke-Geschwind (WG) model for speech processing is expanded to a two-route model involving a direct route between Broca's and Wernicke's area and an indirect route involving the parietal lobe... - Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging studyChristopher J Brubaker
Cincinnati Children s Environmental Health Center at the Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Neurotoxicology 30:867-75. 2009..This study indicates that childhood lead exposure is associated with a significant and persistent impact on white matter microstructure as quantified with diffusivity changes suggestive of altered myelination and axonal integrity... - The effect of musical training on the neural correlates of math processing: a functional magnetic resonance imaging study in humansVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
Neurosci Lett 354:193-6. 2004..We hypothesize that the correlation between musical training and math proficiency may be associated with improved working memory performance and an increased abstract representation of numerical quantities... - Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging studyVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave, Suite R050A, Cincinnati, OH 45229, USA
Radiology 222:212-8. 2002..To evaluate differences in white matter diffusion properties as a function of age in healthy children and adolescents... - A linear structural equation model for covert verb generation based on independent component analysis of FMRI data from children and adolescentsPrasanna Karunanayaka
Center for NMR Research, Department of Radiology, The Pennsylvania State University College of Medicine Hershey, PA, USA
Front Syst Neurosci 5:29. 2011.... - Differences in white matter architecture between musicians and non-musicians: a diffusion tensor imaging studyVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, Suite R056A, Cincinnati, OH 45229, USA
Neurosci Lett 321:57-60. 2002..Further areas also showed significant differences. We hypothesize that these changes are due to the cognitive and motor effects, respectively, of musical training... - Comparison of three methods for generating group statistical inferences from independent component analysis of functional magnetic resonance imaging dataVincent J Schmithorst
Imaging Research Center, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Magn Reson Imaging 19:365-8. 2004..To evaluate the relative effectiveness of three previously proposed methods of performing group independent component analysis (ICA) of functional magnetic resonance imaging (fMRI) data... - Assessment of spatial normalization of whole-brain magnetic resonance images in childrenMarko Wilke
Imaging Research Center, Children s Hospital Research Foundation at Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Hum Brain Mapp 17:48-60. 2002..Also, to minimize the amount of deformation during non-linear spatial normalization, a pediatric template should be used. Further implications of our findings on developmental neuroimaging studies are discussed... - Neural correlates of phonological processing in speech sound disorder: a functional magnetic resonance imaging studyJean A Tkach
Case Center of Imaging Research, Department of Radiology, Case Western Reserve University, Cleveland, OH, USA
Brain Lang 119:42-9. 2011..These findings may be interpreted to support the hypothesis that individuals with SSD may have a deficit in PM and to suggest the involvement of compensatory mechanisms to counteract dysfunction of the normal network... - Chronic isolated hemifacial spasm as a manifestation of epilepsia partialis continuaAlberto J Espay
Department of Neurology and the Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 12:332-6. 2008.... - Event-related fMRI technique for auditory processing with hemodynamics unrelated to acoustic gradient noiseVincent J Schmithorst
Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Magn Reson Med 51:399-402. 2004.... - Cerebral ischemia-hypoxia induces intravascular coagulation and autophagyFaisal Adhami
Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Room 3464, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Am J Pathol 169:566-83. 2006..Together, these results suggest that ischemia-hypoxia is a powerful stimulus for spontaneous coagulation leading to reperfusion deficits and autophagic/lysosomal cell death in brain... - Mapping T2 relaxation time in the pediatric knee: feasibility with a clinical 1.5-T MR imaging systemBernard J Dardzinski
Department of Pediatrics, Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Radiology 225:233-9. 2002..To determine the feasibility of mapping the spatial variation of cartilage T2 relaxation time in vivo in the pediatric knee with a 1.5-T clinical magnetic resonance (MR) imaging system and the manufacturer's body gradient coil... - Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosisJohn J Bissler
Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
N Engl J Med 358:140-51. 2008..The drug sirolimus suppresses mTOR signaling... - A STAP algorithm approach to fMRI: a simulation studyElizabeth A Thompson
Department of Engineering, Purdue University, Fort Wayne, Indiana 46805 1499, USA
J Magn Reson Imaging 20:715-22. 2004.... - A longitudinal functional magnetic resonance imaging study of language development in children 5 to 11 years oldJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, OH, USA
Ann Neurol 59:796-807. 2006..CONCLUSION: The age-related changes observed in this study provide evidence of increased neuroplasticity of language in this age group and may have implications for further investigations of normal and aberrant language development... - Making memories: a cross-sectional investigation of episodic memory encoding in childhood using FMRIC Y Peter Chiu
Department of Psychology and Communication Sciences and Disorders, University of Cincinnati, OH 45221 0376, USA
Dev Neuropsychol 29:321-40. 2006..These results illustrate both similarities and differences in how brain systems interact in development to mediate the formation of episodic memories... - A combined bootstrap/histogram analysis approach for computing a lateralization index from neuroimaging dataMarko Wilke
Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Hoppe Seyler Str 1, 72076 Tubingen, Germany
Neuroimage 33:522-30. 2006..We conclude that the proposed methods yield a robust and specific lateralization index, sensitively detect outliers and allow to assess the underlying data quality...
Research Grants
- Cortical Reorganization in Children with Unilateral Sensorineural Hearing LossVincent Schmithorst; Fiscal Year: 2007....