Vincent J Schmithorst

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Cortical reorganization in children with unilateral sensorineural hearing loss
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroreport 16:463-7. 2005
  2. pmc Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI study
    Vincent J Schmithorst
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, OH 45229, USA
    Hum Brain Mapp 26:139-47. 2005
  3. pmc Sex differences in the development of neuroanatomical functional connectivity underlying intelligence found using Bayesian connectivity analysis
    Vincent J Schmithorst
    Pediatric Brain Imaging Research Program, Imaging Research Center, Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 35:406-19. 2007
  4. ncbi request reprint Empirical validation of the triple-code model of numerical processing for complex math operations using functional MRI and group Independent Component Analysis of the mental addition and subtraction of fractions
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 22:1414-20. 2004
  5. pmc Object identification and lexical/semantic access in children: a functional magnetic resonance imaging study of word-picture matching
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Hum Brain Mapp 28:1060-74. 2007
  6. doi request reprint White matter development during adolescence as shown by diffusion MRI
    Vincent J Schmithorst
    Pediatric Neuroimaging Research Consortium, Dept of Radiology, Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Brain Cogn 72:16-25. 2010
  7. pmc Cognitive modules utilized for narrative comprehension in children: a functional magnetic resonance imaging study
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
    Neuroimage 29:254-66. 2006
  8. pmc Development of effective connectivity for narrative comprehension in children
    Vincent J Schmithorst
    Pediatric Neuroimaging Research Consortium, Imaging Research Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
    Neuroreport 18:1411-5. 2007
  9. pmc Higher-order contrast functions improve performance of independent component analysis of fMRI data
    Vincent J Schmithorst
    Pediatric Neuroimaging Research Consortium, Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Magn Reson Imaging 29:242-9. 2009
  10. ncbi request reprint Functional MRI evidence for disparate developmental processes underlying intelligence in boys and girls
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 31:1366-79. 2006

Research Grants

Collaborators

Detail Information

Publications44

  1. pmc Cortical reorganization in children with unilateral sensorineural hearing loss
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroreport 16:463-7. 2005
    ..The results provide preliminary evidence of disparate neural circuitry supporting auditory processing in participants with left and right USNHL...
  2. pmc Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI study
    Vincent J Schmithorst
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, OH 45229, USA
    Hum Brain Mapp 26:139-47. 2005
    ..The results are consistent with the hypothesis that regionally specific increased fiber organization is a mechanism responsible for the normal development of white matter tracts...
  3. pmc Sex differences in the development of neuroanatomical functional connectivity underlying intelligence found using Bayesian connectivity analysis
    Vincent J Schmithorst
    Pediatric Brain Imaging Research Program, Imaging Research Center, Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 35:406-19. 2007
    ..Our results demonstrate a sexual dimorphism in the relationship of functional connectivity to intelligence in children and an increasing reliance on inter-hemispheric connectivity in girls with age...
  4. ncbi request reprint Empirical validation of the triple-code model of numerical processing for complex math operations using functional MRI and group Independent Component Analysis of the mental addition and subtraction of fractions
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 22:1414-20. 2004
    ....
  5. pmc Object identification and lexical/semantic access in children: a functional magnetic resonance imaging study of word-picture matching
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Hum Brain Mapp 28:1060-74. 2007
    ..The results corroborate the continued development of the ventral visual pathway throughout the developmental period...
  6. doi request reprint White matter development during adolescence as shown by diffusion MRI
    Vincent J Schmithorst
    Pediatric Neuroimaging Research Consortium, Dept of Radiology, Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Brain Cogn 72:16-25. 2010
    ..There is a need for more research to further elucidate the development of white matter and its relation to cognitive function during this critical developmental period...
  7. pmc Cognitive modules utilized for narrative comprehension in children: a functional magnetic resonance imaging study
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
    Neuroimage 29:254-66. 2006
    ..The results are discussed in light of recent hypotheses involving the functional segregation of Wernicke's area and the specific role of the mid-superior temporal gyrus in speech comprehension...
  8. pmc Development of effective connectivity for narrative comprehension in children
    Vincent J Schmithorst
    Pediatric Neuroimaging Research Consortium, Imaging Research Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
    Neuroreport 18:1411-5. 2007
    ..The results demonstrate the feasibility of performing multi subject multivariate autoregressive modeling analyses to investigate effective connectivity in the absence of an a priori model...
  9. pmc Higher-order contrast functions improve performance of independent component analysis of fMRI data
    Vincent J Schmithorst
    Pediatric Neuroimaging Research Consortium, Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Magn Reson Imaging 29:242-9. 2009
    ....
  10. ncbi request reprint Functional MRI evidence for disparate developmental processes underlying intelligence in boys and girls
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 31:1366-79. 2006
    ..Our results provide evidence for disparate neuroanatomical trajectories underlying intelligence in boys and girls...
  11. pmc Diffusion tensor imaging reveals white matter microstructure correlations with auditory processing ability
    Vincent J Schmithorst
    Department of Radiology, Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Ear Hear 32:156-67. 2011
    ..In addition, we hypothesize that the regions displaying correlations will vary according to the task because each task uses a different set of skills...
  12. ncbi request reprint Separate cortical networks involved in music perception: preliminary functional MRI evidence for modularity of music processing
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Avenue, ML 5031, Cincinnati, OH 45229, USA
    Neuroimage 25:444-51. 2005
    ..The results suggest that, while some networks overlap with ones used for language processing, music processing may involve its own domain-specific processing subsystems...
  13. pmc fMRI shows atypical language lateralization in pediatric epilepsy patients
    Weihong Yuan
    Cincinnati Children s Hospital Medical Center, Imaging Research Center, Cincinnati, Ohio 45229, USA
    Epilepsia 47:593-600. 2006
    ..The goal of this study was to compare language lateralization between pediatric epilepsy patients and healthy children...
  14. pmc Functional MRI of language lateralization during development in children
    Scott K Holland
    Pediatric Neuroimaging Research Consortium, Cincinnati Children s Research Foundation, University of Cincinnati, OH 45229, USA
    Int J Audiol 46:533-51. 2007
    ..This review emphasizes the importance of considering age and child development in neuroimaging studies of language...
  15. ncbi request reprint The effect of musical training on music processing: a functional magnetic resonance imaging study in humans
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Mail Location 5031, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Neurosci Lett 348:65-8. 2003
    ..The inferior parietal lobules were recruited only by musicians for both tasks. We conclude that musical training results in the recruitment of different neural networks for these aspects of music processing...
  16. pmc Left-handedness and language lateralization in children
    Jerzy P Szaflarski
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, USA
    Brain Res 1433:85-97. 2012
    ..e., independent of handedness) indicating the presence of similar mechanisms for language lateralization in left- and right-handed children...
  17. doi request reprint Functional magnetic resonance imaging of cognitive processing in young adults with Down syndrome
    Lisa M Jacola
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Am J Intellect Dev Disabil 116:344-59. 2011
    ..These findings supported the authors' hypothesis that persons with Down syndrome demonstrate atypical neural activation compared with typically developing individuals matched for chronological age...
  18. pmc Language networks in children: evidence from functional MRI studies
    Jennifer Vannest
    Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Research Foundation and Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 5033, USA
    AJR Am J Roentgenol 192:1190-6. 2009
    ..The purpose of our study was to review functional MRI and other neuroimaging studies of language skills in children from infancy to adulthood...
  19. pmc Developmental differences in white matter architecture between boys and girls
    Vincent J Schmithorst
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Hum Brain Mapp 29:696-710. 2008
    ..The results also may have implications for the study of the relationship of brain architecture with intelligence...
  20. doi request reprint A group independent component analysis of covert verb generation in children: a functional magnetic resonance imaging study
    Prasanna Karunanayaka
    Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, and Department of Neurology and Center for Imaging Research, University of Cincinnati, Cincinnati, OH 45229, USA
    Neuroimage 51:472-87. 2010
    ..In this context, group ICA of fMRI data from our large sample of children aged 5-18 years provides strong evidence in support of the regionally weighted model for cognitive neurodevelopment of language networks...
  21. pmc fMRI study of language lateralization in children and adults
    Jerzy P Szaflarski
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0525, USA
    Hum Brain Mapp 27:202-12. 2006
    ..Our findings indicate that language lateralization to the dominant hemisphere increases between the ages 5 and 20 years, plateaus between 20 and 25 years, and slowly decreases between 25 and 70 years...
  22. doi request reprint Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis
    Vincent J Schmithorst
    Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    AJR Am J Roentgenol 192:1037-44. 2009
    ..The purpose of our study was to develop a new method for quantifying the severity of cystic lung disease using chest CT and to evaluate this method in patients with lymphangioleiomyomatosis (LAM)...
  23. ncbi request reprint High-resolution functional MRI at 3T in healthy and epilepsy subjects: hippocampal activation with picture encoding task
    Jerzy P Szaflarski
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH, USA
    Epilepsy Behav 5:244-52. 2004
    ..Furthermore, these results suggest that a larger study to test the utility of high-resolution fMRI in epilepsy presurgical evaluation is needed...
  24. ncbi request reprint Sound blending in the brain: a functional magnetic resonance imaging investigation
    C Y Peter Chiu
    Department of Psychology, University of Cincinnati, Cincinnati, Ohio, USA
    Neuroreport 16:883-6. 2005
    ..Our findings are consistent with prior studies ascribing a role of general sequencing, motor and articulatory programming, and vocal or subvocal articulatory rehearsal to this brain region...
  25. pmc Comparison of fMRI data from passive listening and active-response story processing tasks in children
    Jennifer J Vannest
    Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, USA
    J Magn Reson Imaging 29:971-6. 2009
    ..We compare a passive listening (PL) story paradigm to an active-response (AR) version including online performance monitoring and a sparse acquisition technique...
  26. ncbi request reprint Age-related connectivity changes in fMRI data from children listening to stories
    Prasanna R Karunanayaka
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
    Neuroimage 34:349-60. 2007
    ..The classical Wernicke-Geschwind (WG) model for speech processing is expanded to a two-route model involving a direct route between Broca's and Wernicke's area and an indirect route involving the parietal lobe...
  27. pmc Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging study
    Christopher J Brubaker
    Cincinnati Children s Environmental Health Center at the Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Neurotoxicology 30:867-75. 2009
    ..This study indicates that childhood lead exposure is associated with a significant and persistent impact on white matter microstructure as quantified with diffusivity changes suggestive of altered myelination and axonal integrity...
  28. ncbi request reprint The effect of musical training on the neural correlates of math processing: a functional magnetic resonance imaging study in humans
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
    Neurosci Lett 354:193-6. 2004
    ..We hypothesize that the correlation between musical training and math proficiency may be associated with improved working memory performance and an increased abstract representation of numerical quantities...
  29. pmc A linear structural equation model for covert verb generation based on independent component analysis of FMRI data from children and adolescents
    Prasanna Karunanayaka
    Center for NMR Research, Department of Radiology, The Pennsylvania State University College of Medicine Hershey, PA, USA
    Front Syst Neurosci 5:29. 2011
    ....
  30. pmc Comparison of three methods for generating group statistical inferences from independent component analysis of functional magnetic resonance imaging data
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Magn Reson Imaging 19:365-8. 2004
    ..To evaluate the relative effectiveness of three previously proposed methods of performing group independent component analysis (ICA) of functional magnetic resonance imaging (fMRI) data...
  31. ncbi request reprint Differences in white matter architecture between musicians and non-musicians: a diffusion tensor imaging study
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Suite R056A, Cincinnati, OH 45229, USA
    Neurosci Lett 321:57-60. 2002
    ..Further areas also showed significant differences. We hypothesize that these changes are due to the cognitive and motor effects, respectively, of musical training...
  32. pmc Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging study
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave, Suite R050A, Cincinnati, OH 45229, USA
    Radiology 222:212-8. 2002
    ..To evaluate differences in white matter diffusion properties as a function of age in healthy children and adolescents...
  33. ncbi request reprint Assessment of spatial normalization of whole-brain magnetic resonance images in children
    Marko Wilke
    Imaging Research Center, Children s Hospital Research Foundation at Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Hum Brain Mapp 17:48-60. 2002
    ..Also, to minimize the amount of deformation during non-linear spatial normalization, a pediatric template should be used. Further implications of our findings on developmental neuroimaging studies are discussed...
  34. pmc Optimized simultaneous ASL and BOLD functional imaging of the whole brain
    Vincent J Schmithorst
    Cincinnati Children s Hospital Medical Center, Pediatric Neuroimaging Research Consortium, Cincinnati, Ohio, USA Children s Hospital of Pittsburgh of UPMC, Dept of Radiology, Pittsburgh, Pennsylvania, USA
    J Magn Reson Imaging 39:1104-17. 2014
    ..Thus, existing combined ASL/BOLD studies have only partial-brain coverage...
  35. pmc Chronic isolated hemifacial spasm as a manifestation of epilepsia partialis continua
    Alberto J Espay
    Department of Neurology and the Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
    Epilepsy Behav 12:332-6. 2008
    ....
  36. pmc Neural correlates of phonological processing in speech sound disorder: a functional magnetic resonance imaging study
    Jean A Tkach
    Case Center of Imaging Research, Department of Radiology, Case Western Reserve University, Cleveland, OH, USA
    Brain Lang 119:42-9. 2011
    ..These findings may be interpreted to support the hypothesis that individuals with SSD may have a deficit in PM and to suggest the involvement of compensatory mechanisms to counteract dysfunction of the normal network...
  37. pmc Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy
    Faisal Adhami
    Division of Developmental Biology, Cincinnati Children s Hospital Research Foundation, Room 3464, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Am J Pathol 169:566-83. 2006
    ..Together, these results suggest that ischemia-hypoxia is a powerful stimulus for spontaneous coagulation leading to reperfusion deficits and autophagic/lysosomal cell death in brain...
  38. ncbi request reprint Event-related fMRI technique for auditory processing with hemodynamics unrelated to acoustic gradient noise
    Vincent J Schmithorst
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Magn Reson Med 51:399-402. 2004
    ....
  39. ncbi request reprint Mapping T2 relaxation time in the pediatric knee: feasibility with a clinical 1.5-T MR imaging system
    Bernard J Dardzinski
    Department of Pediatrics, Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Radiology 225:233-9. 2002
    ..To determine the feasibility of mapping the spatial variation of cartilage T2 relaxation time in vivo in the pediatric knee with a 1.5-T clinical magnetic resonance (MR) imaging system and the manufacturer's body gradient coil...
  40. pmc Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
    John J Bissler
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    N Engl J Med 358:140-51. 2008
    ..The drug sirolimus suppresses mTOR signaling...
  41. pmc A longitudinal functional magnetic resonance imaging study of language development in children 5 to 11 years old
    Jerzy P Szaflarski
    Department of Neurology, University of Cincinnati Medical Center, OH, USA
    Ann Neurol 59:796-807. 2006
    ..The aim of this study was to conduct a 5-year longitudinal investigation of language development using functional magnetic resonance imaging in healthy children...
  42. ncbi request reprint A STAP algorithm approach to fMRI: a simulation study
    Elizabeth A Thompson
    Department of Engineering, Purdue University, Fort Wayne, Indiana 46805 1499, USA
    J Magn Reson Imaging 20:715-22. 2004
    ....
  43. ncbi request reprint Making memories: a cross-sectional investigation of episodic memory encoding in childhood using FMRI
    C Y Peter Chiu
    Department of Psychology and Communication Sciences and Disorders, University of Cincinnati, OH 45221 0376, USA
    Dev Neuropsychol 29:321-40. 2006
    ..These results illustrate both similarities and differences in how brain systems interact in development to mediate the formation of episodic memories...
  44. ncbi request reprint A combined bootstrap/histogram analysis approach for computing a lateralization index from neuroimaging data
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Hoppe Seyler Str 1, 72076 Tubingen, Germany
    Neuroimage 33:522-30. 2006
    ..We conclude that the proposed methods yield a robust and specific lateralization index, sensitively detect outliers and allow to assess the underlying data quality...

Research Grants2