Affiliation: Cincinnati Children's Hospital Medical Center
- De novo synthesis of VP16 coordinates the exit from HSV latency in vivoRichard L Thompson
Department of Molecular Genetics, Microbiology, and Biochemistry, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA
PLoS Pathog 5:e1000352. 2009..HSV reactivation from latency conforms to a model in which stochastic derepression of the VP16 promoter and expression of VP16 initiates entry into the lytic cycle...
- Herpes simplex virus mutant generation and dual-detection methods for gaining insight into latent/lytic cycles in vivoNancy M Sawtell
Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, MLC 7017, Cincinnati, OH, 45229 3039, USA
Methods Mol Biol 1144:129-47. 2014..Our strategy and protocols for generating, characterizing, and employing HSV viral promoter/reporter mutants in vivo are provided in this two-part chapter. ..
- VP16 serine 375 is a critical determinant of herpes simplex virus exit from latency in vivoNancy M Sawtell
Department of Pediatrics, Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Neurovirol 17:546-51. 2011....
- MOLECULAR ANALYSIS OF HSV-1 REACTIVATION FROM LATENCYNancy Sawtell; Fiscal Year: 2007..These analytical tools together with precision engineering of the viral genome and advances in the analysis of chromatin structure will be utilized for these studies. [unreadable] [unreadable]..