P E Putnam

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi request reprint Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis
    Richard J Noel
    Department of Pediatrics, Cincinnati Children s Medical Center, Universityof Cincinnati College of Medicine, OH 45229 3039, USA
    Clin Gastroenterol Hepatol 2:568-75. 2004
  2. doi request reprint Eosinophilic esophagitis in children: clinical manifestations
    Philip E Putnam
    Cincinnati Center for Eosinophilic Disorders, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Gastroenterol Clin North Am 37:369-81, vi. 2008
  3. ncbi request reprint Eosinophilic esophagitis
    P E Putnam
    Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s, Hospital Medical Center, Cincinnati, OH, USA
    Minerva Gastroenterol Dietol 56:139-57. 2010
  4. ncbi request reprint Eosinophilic esophagitis: concepts, controversies, and evidence
    Philip E Putnam
    Division of Gastroenterology, Hepatology, and Nutrition, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati Center for Eosinophilic Disorders, Cincinnati, OH 45229, USA
    Curr Gastroenterol Rep 11:220-5. 2009
  5. doi request reprint Evaluation of the child who has eosinophilic esophagitis
    Philip E Putnam
    Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, ML 2010, Cincinnati, OH 45229, USA
    Immunol Allergy Clin North Am 29:1-10, vii. 2009
  6. ncbi request reprint Eosinophilic esophagitis in children: clinical manifestations
    Philip E Putnam
    Cincinnati Center for Eosinophilic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, ML 2010, Cincinnati, OH 45229, USA
    Gastrointest Endosc Clin N Am 18:11-23; vii. 2008
  7. pmc Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis
    M Vicario
    Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Gut 59:12-20. 2010
  8. pmc Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses
    C Blanchard
    Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Mucosal Immunol 1:289-96. 2008
  9. pmc Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
    J D Sherrill
    Divisions of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3026, USA
    Mucosal Immunol 7:718-29. 2014
  10. pmc Clinical, pathologic, and molecular characterization of familial eosinophilic esophagitis compared with sporadic cases
    Margaret H Collins
    Division of Pathology and Laboratory Medicine, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Clin Gastroenterol Hepatol 6:621-9. 2008

Collaborators

  • M E Rothenberg
  • Margaret H Collins
  • Seema Khan
  • Seema S Aceves
  • Karen B Zur
  • Ah Filipovich
  • Susan R Orenstein
  • Simon P Hogan
  • J D Molkentin
  • Carine Blanchard
  • Richard J Noel
  • Michael R Konikoff
  • Amal H Assa'ad
  • Bridget K Buckmeier
  • C Blanchard
  • Sean C Jameson
  • J P Abonia
  • M K Mingler
  • Jesus R Guajardo
  • Anil Mishra
  • J Pablo Abonia
  • Jennifer Z Bullock
  • Cassie Kirby
  • J D Sherrill
  • Mitchell B Cohen
  • M Vicario
  • Cassie L Kirby
  • Patricia C Fulkerson
  • Rachel M Akers
  • Joyce M Villanueva
  • Rachel Akers
  • Charles W Debrosse
  • Miguel L Stein
  • K Kc
  • R C Orlando
  • K A Kemme
  • E S Dellon
  • E M Stucke
  • J M Caldwell
  • M S Costello
  • Z Djukic
  • D Wu
  • A Ahrens
  • K F Stringer
  • J Santos
  • Meiqin Wang
  • M McBride
  • K Stringer
  • Venkatarajani R Pemmaraju
  • G Chang
  • Maria Vicario
  • Yi Ying Wu
  • Ann R Collier
  • Melissa K Mingler
  • Thomas X Lu
  • Kimberly A Risma
  • Susanne I Wells
  • Ning Wang
  • Justin W Case
  • Jonathan P Kushner
  • James E Heubi
  • Bruce J Aronow
  • Keith F Stringer
  • Michael K Farrell
  • Lili Miles
  • Jennifer M Fende
  • Lauren M Plotnick

Detail Information

Publications26

  1. ncbi request reprint Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis
    Richard J Noel
    Department of Pediatrics, Cincinnati Children s Medical Center, Universityof Cincinnati College of Medicine, OH 45229 3039, USA
    Clin Gastroenterol Hepatol 2:568-75. 2004
    ..Eosinophilic esophagitis (EE) is a recently recognized clinical disorder that is understood poorly. We aimed to determine the efficacy of swallowed fluticasone propionate on the immunopathologic features associated with EE...
  2. doi request reprint Eosinophilic esophagitis in children: clinical manifestations
    Philip E Putnam
    Cincinnati Center for Eosinophilic Disorders, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Gastroenterol Clin North Am 37:369-81, vi. 2008
    ....
  3. ncbi request reprint Eosinophilic esophagitis
    P E Putnam
    Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s, Hospital Medical Center, Cincinnati, OH, USA
    Minerva Gastroenterol Dietol 56:139-57. 2010
    ..The complications of untreated disease include fibrosis of the esophageal lamina propria and stricture formation that result in chronic dysphagia, risking food impaction and perforation...
  4. ncbi request reprint Eosinophilic esophagitis: concepts, controversies, and evidence
    Philip E Putnam
    Division of Gastroenterology, Hepatology, and Nutrition, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati Center for Eosinophilic Disorders, Cincinnati, OH 45229, USA
    Curr Gastroenterol Rep 11:220-5. 2009
    ..Intense investigations to explain the underpinnings of the disorder and to discover effective therapy are ongoing...
  5. doi request reprint Evaluation of the child who has eosinophilic esophagitis
    Philip E Putnam
    Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, ML 2010, Cincinnati, OH 45229, USA
    Immunol Allergy Clin North Am 29:1-10, vii. 2009
    ..This article summarizes the issues facing the patient and the physician during this process...
  6. ncbi request reprint Eosinophilic esophagitis in children: clinical manifestations
    Philip E Putnam
    Cincinnati Center for Eosinophilic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, ML 2010, Cincinnati, OH 45229, USA
    Gastrointest Endosc Clin N Am 18:11-23; vii. 2008
    ....
  7. pmc Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis
    M Vicario
    Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Gut 59:12-20. 2010
    ....
  8. pmc Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses
    C Blanchard
    Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Mucosal Immunol 1:289-96. 2008
    ....
  9. pmc Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
    J D Sherrill
    Divisions of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3026, USA
    Mucosal Immunol 7:718-29. 2014
    ....
  10. pmc Clinical, pathologic, and molecular characterization of familial eosinophilic esophagitis compared with sporadic cases
    Margaret H Collins
    Division of Pathology and Laboratory Medicine, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Clin Gastroenterol Hepatol 6:621-9. 2008
    ..Eosinophilic esophagitis (EE) occurs in families...
  11. ncbi request reprint IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids
    Carine Blanchard
    Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Allergy Clin Immunol 120:1292-300. 2007
    ..Early studies have established that esophageal eosinophilia occurs in association with T(H)2 allergic responses, and we recently identified an EE-specific esophageal transcriptome that included eotaxin-3...
  12. ncbi request reprint Interplay of adaptive th2 immunity with eotaxin-3/c-C chemokine receptor 3 in eosinophilic esophagitis
    Jennifer Z Bullock
    Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    J Pediatr Gastroenterol Nutr 45:22-31. 2007
    ..Although studies of esophageal tissue suggest that Th2 cytokines and eotaxin-3 may be crucial in disease pathogenesis, little is known about the systemic immunological phenotypes of children with EE...
  13. ncbi request reprint Pediatric patients with eosinophilic esophagitis: an 8-year follow-up
    Amal H Assa'ad
    Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Allergy Clin Immunol 119:731-8. 2007
    ..Eosinophilic esophagitis (EE) is a gastrointestinal disorder that is increasingly diagnosed in pediatric patients...
  14. ncbi request reprint Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis
    Miguel L Stein
    Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Allergy Clin Immunol 118:1312-9. 2006
    ..IL-5 promotes eosinophil trafficking to the esophagus, and positively regulates eosinophil growth, activation, survival, and tissue recruitment...
  15. ncbi request reprint A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis
    Michael R Konikoff
    Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Gastroenterology 131:1381-91. 2006
    ..Although several therapies are advocated, no placebo-controlled trials have been conducted. We aimed to determine the efficacy of swallowed fluticasone propionate (FP) in the treatment of eosinophilic esophagitis...
  16. ncbi request reprint Eosinophilic esophagitis: strictures, impactions, dysphagia
    Seema Khan
    Division of Pediatric Gastroenterology, University of Pittsburgh School of Medicine, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, Pennsylvania 15213 2583, USA
    Dig Dis Sci 48:22-9. 2003
    ....
  17. ncbi request reprint Quantity and distribution of eosinophils in the gastrointestinal tract of children
    Charles W Debrosse
    University of Cincinnati College of Medicine, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Pediatr Dev Pathol 9:210-8. 2006
    ..05). Atopic and nonatopic patients had comparable numbers of eosinophils. These data establish baseline gastrointestinal eosinophil values in pediatric patients without apparent pathological disease...
  18. ncbi request reprint Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry
    Jesus R Guajardo
    Division of Allergy and Immunology, Department of Pediatrics, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Pediatr 141:576-81. 2002
    ....
  19. ncbi request reprint And the winner is...unhappy coexistence
    Philip E Putnam
    J Pediatr 143:147-8. 2003
  20. ncbi request reprint Eosinophilic esophagitis
    Richard J Noel
    N Engl J Med 351:940-1. 2004
  21. ncbi request reprint Clinical quiz: rectal prolapse
    Richard J Noel
    Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, Ohio, USA
    J Pediatr Gastroenterol Nutr 39:567, 575. 2004
  22. pmc Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis
    Carine Blanchard
    Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    J Clin Invest 116:536-47. 2006
    ..Finally, mice deficient in the eotaxin receptor (also known as CCR3) were protected from experimental EE. These results implicate eotaxin-3 as a critical effector molecule for EE and provide insight into disease pathogenesis...
  23. pmc Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia
    Anil Mishra
    Division of Allergy and Immunology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Gastroenterology 134:204-14. 2008
    ..We hypothesized that the development of EE in patients and in an experimental murine model would be associated with eosinophil-mediated tissue remodeling...
  24. ncbi request reprint Potential of blood eosinophils, eosinophil-derived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis
    Michael R Konikoff
    Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3039, USA
    Clin Gastroenterol Hepatol 4:1328-36. 2006
    ..The aim of this study was to identify noninvasive biomarkers that correlated with disease activity and response to treatment as measured by esophageal eosinophilia...
  25. ncbi request reprint Combined retrograde and anterograde hypopharyngeal puncture and dilatation in a child with complete hypopharyngeal stenosis
    Karen B Zur
    Division of Pediatric Otolaryngology Head and Neck Surgery, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, ML 2018 Cincinnati, OH 45229 3039, USA
    Int J Pediatr Otorhinolaryngol 71:153-7. 2007
    ..We observed no major complications following dilatations. At 33 months follow-up the patient was asymptomatic, tolerating a near normal diet, had not required dilation for more than 18 months, and no longer required a gastrostomy tube...
  26. ncbi request reprint GERD and crying: cause and effect or unhappy coexistence?
    Philip E Putnam
    J Pediatr 140:3-4. 2002