Kathryn A Niese
Affiliation: Cincinnati Children's Hospital Medical Center
- Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in miceKathryn A Niese
Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
BMC Immunol 10:33. 2009..Arginase is significantly upregulated in the lungs in murine models of asthma, as well as in human asthma, but its role in allergic airway inflammation has not been fully elucidated in mice...
- The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosisKathryn A Niese
Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, Ohio 45229, USA
Respir Res 11:87. 2010..As such, arginine has the potential to influence diverse fundamental processes in the lung...
- Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent mannerLeah C Kottyan
Cincinnati Children s Hospital Medical Center, OH, USA
Blood 114:2774-82. 2009..We conclude that eosinophil viability is increased in acidic microenvironments in a cAMP- and GPR65-dependent manner...