Ardythe Morrow

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Fucosyltransferase 2 non-secretor and low secretor status predicts severe outcomes in premature infants
    Ardythe L Morrow
    Division of Neonatology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45213, USA
    J Pediatr 158:745-51. 2011
  2. ncbi request reprint Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea
    Ardythe L Morrow
    Center for Epidemiology and Biostatistics, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, OH, USA
    J Nutr 135:1304-7. 2005
  3. ncbi request reprint Human milk protection against infectious diarrhea: implications for prevention and clinical care
    Ardythe L Morrow
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, 5041, Cincinnati, OH 45229 3039, USA
    Semin Pediatr Infect Dis 15:221-8. 2004
  4. ncbi request reprint Human milk oligosaccharide blood group epitopes and innate immune protection against campylobacter and calicivirus diarrhea in breastfed infants
    A L Morrow
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Exp Med Biol 554:443-6. 2004
  5. pmc Norovirus and histo-blood group antigens: demonstration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patterns
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    J Virol 79:6714-22. 2005
  6. ncbi request reprint Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Infect Dis 188:19-31. 2003
  7. doi request reprint The carbohydrate moiety and high molecular weight carrier of histo-blood group antigens are both required for norovirus-receptor recognition
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Glycoconj J 26:1085-96. 2009
  8. ncbi request reprint Adiponectin is present in human milk and is associated with maternal factors
    Lisa J Martin
    Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Am J Clin Nutr 83:1106-11. 2006
  9. pmc Spike protein VP8* of human rotavirus recognizes histo-blood group antigens in a type-specific manner
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Virol 86:4833-43. 2012
  10. pmc Use of a body proportionality index for growth assessment of preterm infants
    Irene E Olsen
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    J Pediatr 154:486-91. 2009

Detail Information

Publications39

  1. pmc Fucosyltransferase 2 non-secretor and low secretor status predicts severe outcomes in premature infants
    Ardythe L Morrow
    Division of Neonatology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45213, USA
    J Pediatr 158:745-51. 2011
    ..To investigate secretor gene fucosyltransferase 2 (FUT2) polymorphism and secretor phenotype in relation to outcomes of prematurity...
  2. ncbi request reprint Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea
    Ardythe L Morrow
    Center for Epidemiology and Biostatistics, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, OH, USA
    J Nutr 135:1304-7. 2005
    ..These novel data open the potential for translational research to develop the human-milk glycans as a new class of antimicrobial agents that prevent infection by acting as pathogen anti-adhesion agents...
  3. ncbi request reprint Human milk protection against infectious diarrhea: implications for prevention and clinical care
    Ardythe L Morrow
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, 5041, Cincinnati, OH 45229 3039, USA
    Semin Pediatr Infect Dis 15:221-8. 2004
    ..The number of deaths of children that could be prevented worldwide each year if these breastfeeding recommendations were followed has been estimated to be more than 1 million...
  4. ncbi request reprint Human milk oligosaccharide blood group epitopes and innate immune protection against campylobacter and calicivirus diarrhea in breastfed infants
    A L Morrow
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Exp Med Biol 554:443-6. 2004
  5. pmc Norovirus and histo-blood group antigens: demonstration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patterns
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    J Virol 79:6714-22. 2005
    ..The high polymorphism of the human HBGA system, the involvement of multiple epitopes, and the typical protein/carbohydrate interaction between norovirus VLPs and HBGAs provide an explanation for the virus-ligand binding diversities...
  6. ncbi request reprint Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Infect Dis 188:19-31. 2003
    ..Oligosaccharides containing the Lewis and ABH antigenic epitopes were involved in binding. Our findings suggest that different strains of NORs may recognize different human HBGAs on intestinal epithelial cells as receptors for infection...
  7. doi request reprint The carbohydrate moiety and high molecular weight carrier of histo-blood group antigens are both required for norovirus-receptor recognition
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Glycoconj J 26:1085-96. 2009
    ..Further studies to define the structure and genetics of the high MW milk glycans are necessary...
  8. ncbi request reprint Adiponectin is present in human milk and is associated with maternal factors
    Lisa J Martin
    Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Am J Clin Nutr 83:1106-11. 2006
    ..If present in milk, adiponectin would be a promising candidate for influencing infant development, given its metabolic functions...
  9. pmc Spike protein VP8* of human rotavirus recognizes histo-blood group antigens in a type-specific manner
    Pengwei Huang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Virol 86:4833-43. 2012
    ..Our results suggest that the spike protein VP8* of RVs is involved in the recognition of human HBGAs that may function as ligands or receptors for RV attachment to host cells...
  10. pmc Use of a body proportionality index for growth assessment of preterm infants
    Irene E Olsen
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    J Pediatr 154:486-91. 2009
    ..To evaluate the utility of weight-for-length (defined as gm/cm(3), known as the "ponderal index") as a complementary measure of growth in infants in neonatal intensive care units (NICUs)...
  11. pmc Human milk adiponectin is associated with infant growth in two independent cohorts
    Jessica G Woo
    Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3039, USA
    Breastfeed Med 4:101-9. 2009
    ..We have previously shown that adiponectin is present in human milk. This study determined whether higher milk adiponectin is associated with infant growth and investigated milk adiponectin's oligomeric form...
  12. ncbi request reprint Varicella-related hospitalization and emergency department visit rates, before and after introduction of varicella vaccine, among white and black children in Hamilton County, Ohio
    Mary Allen Staat
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatrics 117:e833-9. 2006
    ..We examined the impact of varicella immunization on population-based rates of pediatric varicella-related hospitalizations and emergency department (ED) visits in the years before and after introduction of varicella vaccine...
  13. ncbi request reprint Determination of coenzyme Q10 in human breast milk by high-performance liquid chromatography
    Peter H Tang
    Division of Pathology and Laboratory Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Biomed Chromatogr 20:1336-43. 2006
    ..Coefficients of variations (CVs) for intra-day and inter-day assay precisions were less than 5%. A total of 194 breast milk samples were analyzed for the CoQ(10) concentration; the mean value was 0.32 +/- 0.21 micromol L(-1)...
  14. pmc Human milk secretory antibodies against attaching and effacing Escherichia coli antigens
    Marita Noguera-Obenza
    Pediatric Infectious Diseases Division, Department of Pediatrics, University of Texas Houston Medical School, 6431 Fannin, Houston, TX 77040, USA
    Emerg Infect Dis 9:545-51. 2003
    ..Only anti-EspA is found in most milk samples from both populations of women. EspA may represent a useful target for an immunization strategy to prevent EHEC disease in humans...
  15. pmc Breastfeeding helps explain racial and socioeconomic status disparities in adolescent adiposity
    Jessica G Woo
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, MLC 5041, Cincinnati, OH 45229 3039, USA
    Pediatrics 121:e458-65. 2008
    ..Racial and socioeconomic status differences in breastfeeding behavior have also been noted. In this study, we formally test whether breastfeeding mediates the relationship between race and socioeconomic status with adolescent adiposity...
  16. ncbi request reprint Familial autoimmune thyroid disease as a risk factor for regression in children with Autism Spectrum Disorder: a CPEA Study
    Cynthia A Molloy
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Ohio 45229 3039, USA
    J Autism Dev Disord 36:317-24. 2006
    ..89; 95% CI: 1.17, 3.10). The only specific autoimmune disorder found to be associated with regression was autoimmune thyroid disease (adjusted OR=2.09; 95% CI: 1.28, 3.41)...
  17. ncbi request reprint Elevated cytokine levels in children with autism spectrum disorder
    Cynthia A Molloy
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, United States
    J Neuroimmunol 172:198-205. 2006
    ..Conclusion: Children with ASD had increased activation of both Th2 and Th1 arms of the adaptive immune response, with a Th2 predominance, and without the compensatory increase in the regulatory cytokine IL-10...
  18. pmc Reporting individual test results of environmental chemicals in breastmilk: potential for premature weaning
    Sheela R Geraghty
    Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229 3039, USA
    Breastfeed Med 3:207-13. 2008
    ..The purpose of this study was to determine if mothers want to know if chemicals are in their breastmilk and if knowing the results would alter their breastfeeding practices...
  19. pmc Epidemiology of necrotizing enterocolitis temporal clustering in two neonatology practices
    Jareen Meinzen-Derr
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Pediatr 154:656-61. 2009
    ..To develop a statistical method for defining clusters of necrotizing enterocolitis (NEC) cases in the neonatal intensive care unit (NICU)...
  20. ncbi request reprint Human milk contains elements that block binding of noroviruses to human histo-blood group antigens in saliva
    Xi Jiang
    Division of Infectious Diseases, Center for Epidemiology and Biostatistics, Department of Pediatrics, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3039, USA
    J Infect Dis 190:1850-9. 2004
    ..Secretor and Lewis, but not A or B antigens, were present in human milk and were responsible for blocking NV binding to receptors and therefore are likely to be decoy receptors that protect breast-fed infants from NV infection...
  21. ncbi request reprint Duration of exclusive breastfeeding and risk of anemia in a cohort of Mexican infants
    Jareen K Meinzen-Derr
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Exp Med Biol 554:395-8. 2004
  22. ncbi request reprint Fucosylated oligosaccharides in human milk in relation to gestational age and stage of lactation
    Barbara Davidson
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Exp Med Biol 554:427-30. 2004
  23. ncbi request reprint Pediatricians' adherence to pneumococcal conjugate vaccine shortage recommendations in 2 national shortages
    Gerry Fairbrother
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Ave, MLC 7014, Cincinnati, OH 45229 3039, USA
    Pediatrics 120:e401-9. 2007
    ....
  24. ncbi request reprint Human milk contains elements that block binding of noroviruses to histo-blood group antigens in saliva
    Xi Jiang
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Exp Med Biol 554:447-50. 2004
  25. pmc Genetic diversity and histo-blood group antigen interactions of rhesus enteric caliciviruses
    Tibor Farkas
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Virol 84:8617-25. 2010
    ....
  26. pmc Predictors of breastmilk expression by 1 month postpartum and influence on breastmilk feeding duration
    Sheela Geraghty
    Center for Breastfeeding Medicine, Perinatal Institute, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45233, USA
    Breastfeed Med 7:112-7. 2012
    ..This study was designed to determine which factors characterize mothers who expressed their milk by the end of 4 weeks postpartum as well as the duration for which they continued any breastmilk feeding...
  27. ncbi request reprint Risk of infant anemia is associated with exclusive breast-feeding and maternal anemia in a Mexican cohort
    Jareen K Meinzen-Derr
    Departament of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    J Nutr 136:452-8. 2006
    ..Infants who are exclusively breast-fed for >6 mo in developing countries may be at increased risk of anemia, especially among mothers with a poor iron status; greater attention to this issue is warranted...
  28. ncbi request reprint Human milk oligosaccharides are associated with protection against diarrhea in breast-fed infants
    Ardythe L Morrow
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    J Pediatr 145:297-303. 2004
    ..To determine the association between maternal milk levels of 2-linked fucosylated oligosaccharide and prevention of diarrhea as a result of Campylobacter, caliciviruses, and diarrhea of all causes in breast-fed infants...
  29. pmc Development of an enzyme immunoassay for detection of sapovirus-specific antibodies and its application in a study of seroprevalence in children
    Tibor Farkas
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Clin Microbiol 44:3674-9. 2006
    ..SV infection is common in the first 2 years of life. The low prevalence of maternal antibodies detected in Mexican children against SVs in this study is unique and needs to be addressed in future studies...
  30. ncbi request reprint Understanding the origin of asthma and its relationship to breastfeeding
    Marsha Wills-Karp
    Division of Immunobiology, Human Milk Research Program, Cincinnati Children s Hospital Research Foundation, Cincinnati, OH 45229, USA
    Adv Exp Med Biol 554:171-91. 2004
    ....
  31. ncbi request reprint The development of a research human milk bank
    Sheela R Geraghty
    Cincinnati Children s Hospital Medical Center, Division of General and Community Pediatrics, Cincinnati, OH 45229, USA
    J Hum Lact 21:59-66. 2005
    ..Development of more research human milk banks can potentially provide resources for multidisciplinary collaboration and advance the study of human milk and lactation...
  32. ncbi request reprint Innate protection conferred by fucosylated oligosaccharides of human milk against diarrhea in breastfed infants
    David S Newburg
    Program in Glycobiology, Shriver Center, University of Massachusetts Medical School, Waltham, MA 02452, USA
    Glycobiology 14:253-63. 2004
    ..We conclude that specific oligosaccharides constitute a major element of an innate immune system of human milk...
  33. ncbi request reprint Human milk glycans protect infants against enteric pathogens
    David S Newburg
    Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Charlestown, Massachusetts 02129 4404, USA
    Annu Rev Nutr 25:37-58. 2005
    ..These protective glycans may prove useful as a basis for the development of novel prophylactic and therapeutic agents that inhibit diseases caused by mucosal pathogens...
  34. ncbi request reprint Human milk alphal,2-linked fucosylated oligosaccharides decrease risk of diarrhea due to stable toxin of E. coli in breastfed infants
    David S Newburg
    Shriver Center of the University of Massachusetts Medical School, Waltham, MA 02452, USA
    Adv Exp Med Biol 554:457-61. 2004
  35. ncbi request reprint Determinants of optimal breast-feeding in peri-urban Guatemala City, Guatemala
    Kirk Dearden
    Brigham Young University, Department of Health Science, Provo, Utah, USA
    Rev Panam Salud Publica 12:185-92. 2002
    ..This survey was conducted to identify factors affecting early initiation of breast-feeding and exclusive breast-feeding among mothers in peri-urban Guatemala City, Guatemala...
  36. ncbi request reprint Evaluation of a lactation support service in a children's hospital neonatal intensive care unit
    Kristine A Gonzalez
    School of Public Health, University of North Carolina at Chapel Hill, USA
    J Hum Lact 19:286-92. 2003
    ..Mothers with infants in the NICU should have access to lactation counseling...
  37. ncbi request reprint The impact of mother-to-mother support on optimal breast-feeding: a controlled community intervention trial in peri-urban Guatemala City, Guatemala
    Kirk Dearden
    Brigham Young University, Department of Health Science, Provo, Utah, USA
    Rev Panam Salud Publica 12:193-201. 2002
    ..To assess the impact that a mother-to-mother support program operated by La Leche League Guatemala had on early initiation of breast-feeding and on exclusive breast-feeding in peri-urban Guatemala City, Guatemala...
  38. ncbi request reprint Protecting, promoting, and supporting breastfeeding among women in the labor force
    Marina Ferreira Rea
    Instituto de Saude, Coordination of Institutes of Research, Secretaria de Estado da Saúde de São Paulo, Brazil
    Adv Exp Med Biol 554:121-32. 2004
    ....
  39. ncbi request reprint Use of quasi-least squares to adjust for two levels of correlation
    Justine Shults
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    Biometrics 58:521-30. 2002
    ....

Research Grants6

  1. CORE--SCIENTIFIC
    Ardythe Morrow; Fiscal Year: 2006
    ..The core will also support analysis of an extant population-based cohort of asthmatic children to test the replication of findings of the asthma case-control study conducted in project by Khurana. ..
  2. Breast milk: Physiology, Biochemistry and Outcomes
    Ardythe Morrow; Fiscal Year: 2006
    ..A list of these publications is found on our society's website (www.isrhml.org.umu.se). ..
  3. The Role of Human Milk in Infant Nutrition and Health
    Ardythe Morrow; Fiscal Year: 2007
    ..abstract_text> ..
  4. Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.
    Ardythe Morrow; Fiscal Year: 2009
    ....
  5. Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.
    Ardythe L Morrow; Fiscal Year: 2010
    ....
  6. Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.
    Ardythe Morrow; Fiscal Year: 2009
    ....