Sean R Moore

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Glutamine and alanyl-glutamine promote crypt expansion and mTOR signaling in murine enteroids
    Sean R Moore
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio
    Am J Physiol Gastrointest Liver Physiol 308:G831-9. 2015
  2. pmc Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine
    Sean R Moore
    Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH 45229 3039, USA
    Dis Model Mech 7:1123-30. 2014
  3. pmc Zinc treatment ameliorates diarrhea and intestinal inflammation in undernourished rats
    Camila A A de Queiroz
    Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Rua Cel, Nunes de Melo, 1315, Fortaleza, CE, Brazil
    BMC Gastroenterol 14:136. 2014
  4. pmc Prolonged episodes of acute diarrhea reduce growth and increase risk of persistent diarrhea in children
    Sean R Moore
    Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Gastroenterology 139:1156-64. 2010
  5. doi request reprint Update on prolonged and persistent diarrhea in children
    Sean R Moore
    Division of Gastroenterology, Hepatology, and Nutrition, Center for Global Child Health, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
    Curr Opin Gastroenterol 27:19-23. 2011
  6. pmc Alanyl-glutamine promotes intestinal epithelial cell homeostasis in vitro and in a murine model of weanling undernutrition
    Priscilla M Ueno
    Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Am J Physiol Gastrointest Liver Physiol 301:G612-22. 2011
  7. doi request reprint Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid
    Eitaro Aihara
    Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio
    Sci Rep 5:17185. 2015
  8. pmc Early childhood growth failure and the developmental origins of adult disease: do enteric infections and malnutrition increase risk for the metabolic syndrome?
    Mark D DeBoer
    Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA
    Nutr Rev 70:642-53. 2012
  9. pmc Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice
    Elizabeth A Maier
    Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH, USA
    Vaccine 32:48-53. 2013
  10. doi request reprint Rhythm and bugs: circadian clocks, gut microbiota, and enteric infections
    Andrew E Rosselot
    aDepartment of Molecular and Cellular Physiology, University of Cincinnati College of Medicine bDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
    Curr Opin Gastroenterol 32:7-11. 2016

Collaborators

  • Reinaldo B Oriá
  • Richard L Guerrant
  • David I Bernstein
  • D Brent Polk
  • Monica M McNeal
  • Elizabeth A Maier
  • Andrew E Rosselot
  • Christian I Hong
  • Eitaro Aihara
  • Camila A A de Queiroz
  • Lee A Denson
  • Mark D DeBoer
  • Aldo A M Lima
  • Priscilla M Ueno
  • Scott Herness
  • Maxime M Mahé
  • Taeko K Noah
  • Ken Iwatsuki
  • Toru Matsu-Ura
  • Noah F Shroyer
  • Wenwen Ren
  • Michael A Helmrath
  • Andrea L Matthis
  • Rui Feng
  • Yana Zavros
  • Peihua Jiang
  • Michael A Schumacher
  • Marshall H Montrose
  • Said Gonçalves C Fonseca
  • Ronaldo A Ribeiro
  • Italo L Figueiredo
  • Priscila B Frota
  • Carlos Emanuel C Magalhães
  • Aldo Angelo M Lima
  • Karoline S Aragão
  • Cibele B M de Carvalho
  • Marjorie M Guedes
  • Kristina J Weage
  • Max A Luna
  • Rebecca J Scharf
  • Marjorie Guedes
  • Tara Willson
  • Simon P Hogan
  • David Wu
  • Orleancio G de Azevedo

Detail Information

Publications10

  1. pmc Glutamine and alanyl-glutamine promote crypt expansion and mTOR signaling in murine enteroids
    Sean R Moore
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio
    Am J Physiol Gastrointest Liver Physiol 308:G831-9. 2015
    ..Collectively, these findings indicate that Gln deprivation induces a reversible quiescence of intestinal stem cells and provides new insights into nutritional regulation of intestinal epithelial homeostasis...
  2. pmc Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine
    Sean R Moore
    Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH 45229 3039, USA
    Dis Model Mech 7:1123-30. 2014
    ..The rhythmic and organotypic features of organoids should offer unprecedented advantages as a resource for elucidating the role of circadian rhythms in GI stem cell dynamics, epithelial homeostasis and disease. ..
  3. pmc Zinc treatment ameliorates diarrhea and intestinal inflammation in undernourished rats
    Camila A A de Queiroz
    Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Rua Cel, Nunes de Melo, 1315, Fortaleza, CE, Brazil
    BMC Gastroenterol 14:136. 2014
    ..In this study, we examined whether oral zinc supplementation could improve weight, intestinal inflammation, and diarrhea in undernourished weanling rats...
  4. pmc Prolonged episodes of acute diarrhea reduce growth and increase risk of persistent diarrhea in children
    Sean R Moore
    Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Gastroenterology 139:1156-64. 2010
    ..Prolonged episodes of acute diarrhea (ProD; duration 7-13 days) or persistent diarrhea (PD; duration ≥14 days) are important causes of undernutrition, yet the epidemiology and nutritional impact of ProD are poorly understood...
  5. doi request reprint Update on prolonged and persistent diarrhea in children
    Sean R Moore
    Division of Gastroenterology, Hepatology, and Nutrition, Center for Global Child Health, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
    Curr Opin Gastroenterol 27:19-23. 2011
    ....
  6. pmc Alanyl-glutamine promotes intestinal epithelial cell homeostasis in vitro and in a murine model of weanling undernutrition
    Priscilla M Ueno
    Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Am J Physiol Gastrointest Liver Physiol 301:G612-22. 2011
    ..In summary, Ala-Gln promotes intestinal epithelial homeostasis in a mouse model of malnutrition-associated enteropathy, mimicking key features of the human disease...
  7. doi request reprint Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid
    Eitaro Aihara
    Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio
    Sci Rep 5:17185. 2015
    ..Additionally, we demonstrate that stem/progenitor cells have motility to form taste bud organoids. Taste bud organoids provides a system for elucidating mechanisms of taste signaling, disease modeling, and taste tissue regeneration. ..
  8. pmc Early childhood growth failure and the developmental origins of adult disease: do enteric infections and malnutrition increase risk for the metabolic syndrome?
    Mark D DeBoer
    Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA
    Nutr Rev 70:642-53. 2012
    ....
  9. pmc Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice
    Elizabeth A Maier
    Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH, USA
    Vaccine 32:48-53. 2013
    ....
  10. doi request reprint Rhythm and bugs: circadian clocks, gut microbiota, and enteric infections
    Andrew E Rosselot
    aDepartment of Molecular and Cellular Physiology, University of Cincinnati College of Medicine bDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
    Curr Opin Gastroenterol 32:7-11. 2016
    ..To highlight recent developments in understanding the dynamic relationship between circadian rhythms, the gut microbiome, and gastrointestinal infections...