Mark M Mitsnefes

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Cardiovascular disease in children with chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Am Soc Nephrol 23:578-85. 2012
  2. ncbi request reprint Hypertension in pediatric patients on long-term dialysis: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Am J Kidney Dis 45:309-15. 2005
  3. ncbi request reprint Adiponectin in children with chronic kidney disease: role of adiposity and kidney dysfunction
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Clin J Am Soc Nephrol 2:46-50. 2007
  4. pmc Cardiovascular complications of pediatric chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Pediatr Nephrol 23:27-39. 2008
  5. ncbi request reprint Blood pressure and total peripheral resistance in children with chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Pediatr Nephrol 20:803-6. 2005
  6. ncbi request reprint Progression of left ventricular hypertrophy in children with early chronic kidney disease: 2-year follow-up study
    Mark M Mitsnefes
    Division of Nephrology and Hypertension and the Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Pediatr 149:671-5. 2006
  7. ncbi request reprint Increasing incidence of post-kidney transplant anemia in children
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, OH, USA
    Am J Transplant 5:1713-8. 2005
  8. ncbi request reprint Cardiovascular morbidity and mortality in children with chronic kidney disease in North America: lessons from the USRDS and NAPRTCS databases
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Perit Dial Int 25:S120-2. 2005
  9. ncbi request reprint Cardiac and vascular adaptation in pediatric patients with chronic kidney disease: role of calcium-phosphorus metabolism
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital, Cincinnati, OH 45229, USA
    J Am Soc Nephrol 16:2796-803. 2005
  10. ncbi request reprint Cardiovascular disease in children with chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Chronic Kidney Dis 12:397-405. 2005

Collaborators

Detail Information

Publications58

  1. pmc Cardiovascular disease in children with chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Am Soc Nephrol 23:578-85. 2012
    ..Slowing the progression of CKD, avoiding long-term dialysis and, if possible, conducting preemptive transplantation may represent the best strategies to decrease the risk of premature cardiac disease and death in children with CKD...
  2. ncbi request reprint Hypertension in pediatric patients on long-term dialysis: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Am J Kidney Dis 45:309-15. 2005
    ..Using the North American Pediatric Renal Transplantation Cooperative Study database, we determined the prevalence of hypertension and assessed risk factors for elevated BP during long-term dialysis therapy in children...
  3. ncbi request reprint Adiponectin in children with chronic kidney disease: role of adiposity and kidney dysfunction
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Clin J Am Soc Nephrol 2:46-50. 2007
    ..Despite overall elevated adiponectin, overweight patients display lower serum adiponectin levels and might be at risk for future cardiovascular complications...
  4. pmc Cardiovascular complications of pediatric chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Pediatr Nephrol 23:27-39. 2008
    ..Recent data indicate that cardiovascular complications are already present in children with CKD. This review summarizes the current literature on cardiac risk factors, mortality and morbidity in children with CKD...
  5. ncbi request reprint Blood pressure and total peripheral resistance in children with chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Pediatr Nephrol 20:803-6. 2005
    ....
  6. ncbi request reprint Progression of left ventricular hypertrophy in children with early chronic kidney disease: 2-year follow-up study
    Mark M Mitsnefes
    Division of Nephrology and Hypertension and the Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Pediatr 149:671-5. 2006
    ....
  7. ncbi request reprint Increasing incidence of post-kidney transplant anemia in children
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, OH, USA
    Am J Transplant 5:1713-8. 2005
    ....
  8. ncbi request reprint Cardiovascular morbidity and mortality in children with chronic kidney disease in North America: lessons from the USRDS and NAPRTCS databases
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Perit Dial Int 25:S120-2. 2005
    ....
  9. ncbi request reprint Cardiac and vascular adaptation in pediatric patients with chronic kidney disease: role of calcium-phosphorus metabolism
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital, Cincinnati, OH 45229, USA
    J Am Soc Nephrol 16:2796-803. 2005
    ....
  10. ncbi request reprint Cardiovascular disease in children with chronic kidney disease
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Adv Chronic Kidney Dis 12:397-405. 2005
    ..Early identification of modifiable risk factors and treatment of asymptomatic CVD might lead to decrease of cardiovascular morbidity and mortality in young adults who developed CKD during childhood...
  11. ncbi request reprint Hypertension in children and adolescents
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pediatr Clin North Am 53:493-512, viii. 2006
    ..Hypertension in children also is viewed as a significant risk factor for the development of cardiovascular disease in adulthood...
  12. ncbi request reprint Serum cystatin C and left ventricular diastolic dysfunction in children with chronic kidney disease
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH, 45229 3039, USA
    Pediatr Nephrol 21:1293-8. 2006
    ..0173, P=0.01). We conclude that, in contrast to measured GFR or serum creatinine level, elevated serum cystatin C might be associated with diastolic dysfunction in children with CKD...
  13. ncbi request reprint Hypertension and end-organ damage in pediatric renal transplantation
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 9039, USA
    Pediatr Transplant 8:394-9. 2004
    ..Aggressive treatment of elevated BP is an essential part of Tx care with the goal to delay graft failure and prevent the development of symptomatic cardiovascular disease in young recipients of renal Tx...
  14. ncbi request reprint Abnormal carotid artery structure and function in children and adolescents with successful renal transplantation
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital, MLC 7022, 3333 Burnet Ave, Cincinnati, Ohio 45229 3039, USA
    Circulation 110:97-101. 2004
    ..However, little is known about the extent of these abnormalities in children after transplantation...
  15. ncbi request reprint Impaired left ventricular diastolic function in children with chronic renal failure
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Kidney Int 65:1461-6. 2004
    ..We compared diastolic function and assessed risk factors associated with diastolic dysfunction in children with CRI with those on dialysis...
  16. ncbi request reprint Left ventricular mass and systolic performance in pediatric patients with chronic renal failure
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, USA
    Circulation 107:864-8. 2003
    ..The aim of this study was to determine the association between LV mass, LV performance, and LV contractility in children with chronic renal insufficiency (CRI) and children undergoing chronic dialysis...
  17. ncbi request reprint Hypertension and progression of chronic renal insufficiency in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Am Soc Nephrol 14:2618-22. 2003
    ..03), acquired cause of renal disease (P = 0.0001), and baseline eGFR <50 ml/min.1.73 m2 (P = 0.0001). Hypertension is a highly significant and independent predictor for progression of CRI in children...
  18. ncbi request reprint Severe cardiac hypertrophy and long-term dialysis: the Midwest Pediatric Nephrology Consortium study
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, MLC 7021, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pediatr Nephrol 21:1167-70. 2006
    ..We conclude that children on maintenance dialysis are at high risk for future cardiovascular disease...
  19. pmc Masked hypertension associates with left ventricular hypertrophy in children with CKD
    Mark Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Am Soc Nephrol 21:137-44. 2010
    ..The high prevalence of masked hypertension and its association with LVH supports early echocardiography and ambulatory BP monitoring to evaluate cardiovascular risk in children with CKD...
  20. ncbi request reprint Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease
    Mark M Mitsnefes
    Divisions of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati School of Medicine, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH, 45229 3039, USA
    Pediatr Nephrol 22:101-8. 2007
    ..62), followed by cystatin C (r=0.41). We conclude that (a) both serum NGAL and cystatin C may prove useful in the quantitation of CKD, and (b) by correlation analysis, NGAL outperforms cystatin C and eGFR at lower levels of measured GFR...
  21. doi request reprint Subclinical systolic dysfunction in pediatric patients with chronic kidney disease
    Donald J Weaver
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Pediatr 153:565-9. 2008
    ..Midwall shortening (mwSF) is thought to be a more accurate measure of myocardial performance in the presence of left ventricular hypertrophy (LVH). We examined mwSF in pediatric patients with varying degrees of chronic kidney disease (CKD)...
  22. pmc Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study
    Catherine L Dent
    Department of Cardiology, Cincinnati Children s Hospital Medical Center, University of Cincinnati School of Medicine, 3333 Burnet Ave, Cincinnati, Ohio 45229, USA
    Crit Care 11:R127. 2007
    ..In this study we tested whether a point-of-care NGAL device can predict AKI after CPB in a larger cohort...
  23. pmc Decreased maximal aerobic capacity in pediatric chronic kidney disease
    Donald J Weaver
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    J Am Soc Nephrol 19:624-30. 2008
    ..These results suggest that aerobic capacity is decreased in the early stages of CKD in children and that lower VO(2) max can be predicted by the presence of diastolic dysfunction, even if systolic function is normal...
  24. ncbi request reprint Abnormal cardiac function in children after renal transplantation
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Am J Kidney Dis 43:721-6. 2004
    ..In adults with a transplant, left ventricular (LV) mass (LVM) is associated with cardiac dysfunction. However, in children with a transplant, the relationship between LVM and LV function has not been evaluated...
  25. ncbi request reprint Early posttransplantation hypertension and poor long-term renal allograft survival in pediatric patients
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Department of Pediatrics, University of Cincinnati College of Medicine and The Children s Hospital Research Foundation, Cincinnati, Ohio 45299 3039, USA
    J Pediatr 143:98-103. 2003
    ..To evaluate the effect of early hypertension on long-term allograft survival in children with kidney transplantation...
  26. doi request reprint Cardiac output and associated left ventricular hypertrophy in pediatric chronic kidney disease
    Donald J Weaver
    Division of Nephrology and Hypertension, Cincinnati Children s Medical Center, Cincinnati, OH 45229, USA
    Pediatr Nephrol 24:565-70. 2009
    ..25). The results of this study suggest that increased CO might predispose to increased LVMI in pediatric patients with CKD. Adaptations may be required to meet increased metabolic demand in these patients...
  27. ncbi request reprint Blood pressure control in pediatric hemodialysis: the Midwest Pediatric Nephrology Consortium Study
    Rene G Vandevoorde
    Division of Pediatric Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Pediatr Nephrol 22:547-53. 2007
    ..Especially poor BP control was found in younger children; those patients who do not reach their posttreatment weight goals, perhaps reflecting their hypervolemic state; and those who have higher serum phosphorus levels...
  28. pmc Prevalence and correlates of multiple cardiovascular risk factors in children with chronic kidney disease
    Amy C Wilson
    Division of Nephrology and Hypertension, J W Riley Hospital for Children, Indianapolis, IN 46202, USA
    Clin J Am Soc Nephrol 6:2759-65. 2011
    ..This study determined the prevalence and characteristics of multiple CVRF in children in the Chronic Kidney Disease in Children study...
  29. ncbi request reprint Body mass index and allograft function in pediatric renal transplantation
    Mark M Mitsnefes
    Division of Nephrology, Department of Pediatrics, University of Cincinnati College of Medicine and The Children s Hospital Research Foundation TCHRF 5, Ohio 45229 3039, USA
    Pediatr Nephrol 17:535-9. 2002
    ..01) than children from other groups. We conclude that pre-Tx obesity is associated with decreased GFR in children at 1 year after Tx. The reason may be persistence or development of post-Tx hypertension in severely obese patients...
  30. ncbi request reprint Induction of renal tubular cell apoptosis in focal segmental glomerulosclerosis: roles of proteinuria and Fas-dependent pathways
    Elif Erkan
    Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    J Am Soc Nephrol 16:398-407. 2005
    ..The results indicate that an elevated tubule cell apoptosis rate at the time of initial biopsy represents an independent predictor of progression to ESRD in patients with early FSGS...
  31. doi request reprint Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy
    Mai T Nguyen
    Department of Pediatrics, Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Nephrol 23:1317-26. 2008
    ..We concluded that urinary aprotinin levels 2 h after initiation of CPB predict the development of AKI and adverse clinical outcomes...
  32. doi request reprint Management of blood pressure in children
    Rossana Malatesta-Muncher
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Curr Opin Nephrol Hypertens 21:318-22. 2012
    ....
  33. ncbi request reprint Office and ambulatory blood pressure elevation in children with chronic renal failure
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, USA
    Pediatr Nephrol 18:145-9. 2003
    ..These results confirm a high prevalence of blood pressure abnormalities using ABPM criteria in children with CRI and suggest that ABP may better predict end-organ damage in these patients than casual BP...
  34. ncbi request reprint Left ventricular hypertrophy in pediatric kidney transplant recipients: long-term follow-up study
    Nathan Bullington
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Pediatr Transplant 10:811-5. 2006
    ..The results of the study suggest that despite regression of LVM index overtime-pediatric patients post-kidney transplant are at continuous risk for developing cardiovascular disease...
  35. doi request reprint High prevalence of the metabolic syndrome and associated left ventricular hypertrophy in pediatric renal transplant recipients
    Amy C Wilson
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Pediatr Transplant 14:52-60. 2010
    ..2-5.9). In conclusion: metabolic syndrome is common at time of pediatric kidney transplant, and prevalence rises sharply at one-yr post-transplant. The presence of metabolic syndrome is strongly associated with LVH in these patients...
  36. ncbi request reprint Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery
    Jaya Mishra
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Lancet 365:1231-8. 2005
    ..We tested the hypothesis that neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for ischaemic renal injury after cardiopulmonary bypass...
  37. pmc Mortality risk among children initially treated with dialysis for end-stage kidney disease, 1990-2010
    Mark M Mitsnefes
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    JAMA 309:1921-9. 2013
    ..Most children with end-stage kidney disease (ESKD) are treated with dialysis prior to transplant. It is not known whether their outcomes have changed in recent years...
  38. pmc Cardiovascular disease in CKD in children: update on risk factors, risk assessment, and management
    Amy C Wilson
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA
    Am J Kidney Dis 54:345-60. 2009
    ..The purpose of this review is to provide an update of recent advances in the understanding and management of cardiovascular disease risks in this population...
  39. doi request reprint Hypertension and CKD
    Rene G Vandevoorde
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Adv Chronic Kidney Dis 18:355-61. 2011
    ....
  40. ncbi request reprint Ambulatory blood pressure monitoring in pediatric renal transplantation
    Mark M Mitsnefes
    Department of Pediatrics, Division of Nephrology and Hypertension, University of Cincinnati College of Medicine and The Children s Hospital Research Foundation, Cincinnati, OH, USA
    Pediatr Transplant 7:86-92. 2003
    ..We will review the importance of hypertension in this patient subset, discuss the advantage of ABPM over CBP and focus on specific abnormalities and clinical significance of ABPM in renal transplant recipients...
  41. ncbi request reprint Hyperinsulinemia in pediatric patients with chronic kidney disease: the role of tumor necrosis factor-alpha
    Hsiao L Lai
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pediatr Nephrol 22:1751-6. 2007
    ..11, P = 0.01). We conclude that hyperinsulinemia and insulin resistance are frequent in pediatric CKD. In lean patients inflammation appears to be an important determinant of serum insulin level...
  42. doi request reprint Flow-mediated vasodilatation of the brachial artery in children with chronic kidney disease
    Amy C Wilson
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Pediatr Nephrol 23:1297-302. 2008
    ..In conclusion, children with CKD stage 2-4 appear to have increased prevalence of decreased FMD of the brachial artery. However, our study identified few significant factors associated with low FMD in children with CKD...
  43. pmc Serum adiponectin complexes and cardiovascular risk in children with chronic kidney disease
    Megan M Lo
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, MLC 7022, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pediatr Nephrol 26:2009-17. 2011
    ..This imbalance may be an important biomarker for increased cardiovascular risk despite higher levels of total adiponectin in children with CKD...
  44. ncbi request reprint Racial differences in graft survival: a report from the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)
    Abiodun Omoloja
    Department of Pediatric Nephrology, Wright State University Boonshoft School of Medicine, Dayton, Ohio, USA
    Clin J Am Soc Nephrol 2:524-8. 2007
    ..65; 95% confidence interval 1.46 to 1.86). Significant racial differences in kidney transplant outcomes exist among pediatric patients even after controlling for confounding factors...
  45. ncbi request reprint Advances in the pathogenesis and management of hypertensive crisis
    Hiren P Patel
    Department of Pediatrics, Children s Hospital, The Ohio State University School of Medicine and Public Health, Columbus, Ohio, USA
    Curr Opin Pediatr 17:210-4. 2005
    ....
  46. ncbi request reprint Evaluation of hypertension by the general pediatrician
    Mai Nguyen
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Curr Opin Pediatr 19:165-9. 2007
    ..To summarize the recommended work-up in a child who presents with elevated blood pressure as well as innovative evaluation techniques under development...
  47. pmc Racial differences in pediatric renal transplantation-24-year single center experience
    Abiodun Omoloja
    Department of Pediatrics, Wright State University School of Medicine, Dayton, OH, USA
    J Natl Med Assoc 98:154-7. 2006
    ..Significant racial differences were noted in number of pre-emptive transplants, type of graft received, height at transplant and causes of ESRD...
  48. ncbi request reprint Kidney NGAL is a novel early marker of acute injury following transplantation
    Jaya Mishra
    Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Nephrol 21:856-63. 2006
    ..We conclude that NGAL staining intensity in early protocol biopsies represents a novel predictive biomarker of acute kidney injury following transplantation...
  49. ncbi request reprint NGAL is an early predictive biomarker of contrast-induced nephropathy in children
    Russel Hirsch
    Division of Cardiology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Nephrol 22:2089-95. 2007
    ..52, p < 0.0001) and plasma (R (2) = 0.72, p < 0.0001) were found to be powerful independent predictors of CIN. Patient demographics and contrast volume were not predictive of CIN...
  50. ncbi request reprint Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury
    Jaya Mishra
    Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Am Soc Nephrol 14:2534-43. 2003
    ..The results indicate that NGAL may represent an early, sensitive, noninvasive urinary biomarker for ischemic and nephrotoxic renal injury...
  51. ncbi request reprint Neonatal renovascular hypertension due to prenatal traumatic retroperitoneal hematoma
    Bradley P Dixon
    Department of Pediatrics, Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatr Nephrol 20:670-2. 2005
    ..Likewise, attention must be drawn to the classic presentation of congestive heart failure in a child with severe hypertension...
  52. ncbi request reprint Activation of mitochondrial apoptotic pathways in human renal allografts after ischemiareperfusion injury
    M Patricia Castaneda
    Division of Nephrology, Children s Hospital at Montefiore, Bronx, New York, USA
    Transplantation 76:50-4. 2003
    ..We tested the hypothesis that activation of specific apoptotic pathways represents a mechanism for tubular cell death after CAD kidney transplantation...
  53. ncbi request reprint Ambulatory blood pressure monitoring: a quest for truth
    Rene G VanDe Voorde
    Pediatr Transplant 11:10-3. 2007
  54. ncbi request reprint Obesity and renal transplant outcome: a report of the North American Pediatric Renal Transplant Cooperative Study
    Coral D Hanevold
    Medical College of Georgia, Augusta, Georgia, USA
    Pediatrics 115:352-6. 2005
    ..Studies that have evaluated the effect of obesity on transplant outcomes in adults have yielded varying results. This issue has received little attention in the pediatric population...
  55. ncbi request reprint Pediatric end-stage renal disease: heart as a target
    Mark M Mitsnefes
    J Pediatr 141:162-4. 2002
  56. doi request reprint Understanding carotid artery intima-media thickness in childhood: lessons from studies in children with renal transplants
    Mark M Mitsnefes
    Pediatr Transplant 12:377-80. 2008
  57. ncbi request reprint Hyperphosphatemia in children receiving peritoneal dialysis--an educational program
    Richard T Blaszak
    Division of Nephrology, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202 3591, USA
    Pediatr Nephrol 20:967-71. 2005
    ....
  58. ncbi request reprint Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: a science advisory from the American Heart Association Kidney And Cardiovascular Disease Council; the Councils on High Blood Pressure Research, Cardiovasc
    Frank C Brosius
    Circulation 114:1083-7. 2006
    ..All patients with cardiovascular disease should be screened for evidence of kidney disease with these two determinations...

Research Grants5

  1. Cardiac disease in children with chronic renal failure
    Mark Mitsnefes; Fiscal Year: 2006
    ..Thus, the long-term goal will be to decrease the incidence and prevalence of cardiovascular disease in young adults who developed chronic renal disease during childhood. ..
  2. Adiponectin and Cardiovascular Disease in the CKiD Children
    Mark Mitsnefes; Fiscal Year: 2007
    ....
  3. Adiponectin and Cardiovascular Disease in the CKiD Children
    Mark Mitsnefes; Fiscal Year: 2009
    ....
  4. Adiponectin and Cardiovascular Disease in the CKiD Children
    Mark Mitsnefes; Fiscal Year: 2009
    ....