Research Topics
| Bradley S MarinoSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Publications
External validity of the pediatric cardiac quality of life inventoryBradley S Marino
Department of Pediatrics, Division of Cardiology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 2003, Cincinnati, OH 45229, USA
Qual Life Res 20:205-14. 2011..The purpose of this study was to demonstrate the external validity of PCQLI scores...
The development of the pediatric cardiac quality of life inventory: a quality of life measure for children and adolescents with heart diseaseBradley S Marino
Department of Pediatrics, Divisions of Cardiology and Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Qual Life Res 17:613-26. 2008..Quality of life (QOL) assessment in survivors has become increasingly important. The purpose of this project was to create the Pediatric Cardiac Quality of Life Inventory (PCQLI)...
Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adultsBradley S Marino
Children s Hospital of Philadelphia, Pediatrics Divisions of Cardiology, Philadelphia, PA, USA
Congenit Heart Dis 3:39-46. 2008....
Quality-of-life concerns differ among patients, parents, and medical providers in children and adolescents with congenital and acquired heart diseaseBradley S Marino
Department of Anesthesiology and Critical Care Medicine, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Pediatrics 123:e708-15. 2009..The purpose of this study was to assess and compare how heart disease affects the quality of life of the pediatric cardiac patient from the perspectives of the patient, parent, and health care provider...
Validation of the pediatric cardiac quality of life inventoryBradley S Marino
Cincinnati Children s Hospital Medical Center, Department of Pediatrics, 3333 Burnet Ave, MLC 5050, Cincinnati, OH 45229, USA
Pediatrics 126:498-508. 2010..The purpose of this multicenter study was to confirm the validity and reliability of the Pediatric Cardiac Quality of Life Inventory (PCQLI)...
Poor post-operative growth in infants with two-ventricle physiologyJeffrey B Anderson
Division of Cardiology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45255, USA
Cardiol Young 21:421-9. 2011..The primary outcome was change in weight-for-age z score from surgery to discharge. Our secondary outcome variable was post-operative hospital length of stay...
Impact of sildenafil on echocardiographic indices of myocardial performance after the Fontan operationDavid J Goldberg
Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Cardiol 33:689-96. 2012..These findings suggest that sildenafil may be a useful therapy to improve or maintain ventricular performance in select patients after the Fontan operation...
Low weight-for-age z-score and infection risk after the Fontan procedureJeffrey B Anderson
Division of Cardiology, Cincinnati Children s Hospital Medical Center, The Heart Institute, Cincinnati, Ohio 45255, USA
Ann Thorac Surg 91:1460-6. 2011..We sought to assess growth status at the time of the Fontan procedure and the effect of poor growth status on surgical outcomes...
Risk factors for interstage death after stage 1 reconstruction of hypoplastic left heart syndrome and variantsDavid A Hehir
Division of Cardiology, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia 19104, USA
J Thorac Cardiovasc Surg 136:94-9, 99.e1-3. 2008..The purpose of this study is to identify risk factors for interstage death and to describe the events leading to interstage death...
Following the arterial switch operation, obese children have risk factors for early cardiovascular diseaseSara K Pasquali
Division of Cardiology, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Congenit Heart Dis 5:16-24. 2010..Obesity may also pose cardiovascular risk. The purpose of this study was to evaluate comorbidities and markers of early cardiovascular disease in obese ASO patients...
Midterm outcomes and predictors of reintervention after the Ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology in the Departments of Pediatrics, Surgery, and Anesthesia Critical Care Medicine at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Thorac Cardiovasc Surg 133:893-9. 2007..This study assessed the type, time course, and risk factors for right and left ventricular outflow tract reinterventions after the Ross procedure in a population of infants, children, and young adults...
Critical heart disease in the neonate: presentation and outcome at a tertiary care centerAaron T Dorfman
Department of Pediatrics, Division of Cardiology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 19104, USA
Pediatr Crit Care Med 9:193-202. 2008..To define the modes of presentation, incidence of major organ dysfunction, predictors of hospital mortality, and adverse outcomes in neonates with critical heart disease admitted to a tertiary care center...
A contemporary comparison of the effect of shunt type in hypoplastic left heart syndrome on the hemodynamics and outcome at stage 2 reconstructionJean A Ballweg
Department of Pediatrics, Division of Cardiology, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19119, USA
J Thorac Cardiovasc Surg 134:297-303. 2007..We compare the hemodynamics and perioperative course of shunt type in hypoplastic left heart syndrome at the time of stage 2 reconstruction and longer-term survival...
The relationship between neo-aortic root dilation, insufficiency, and reintervention following the Ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Am Coll Cardiol 49:1806-12. 2007..The purpose of this study was to describe the relationship between neo-aortic root size, neo-aortic insufficiency (AI), and reintervention at mid-term follow-up...
Risk factors and comorbidities associated with obesity in children and adolescents after the arterial switch operation and Ross procedureSara K Pasquali
The Division of Cardiology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am Heart J 158:473-9. 2009..Unique factors such as activity restriction and early feeding practices may play a role. We evaluated a high-risk cohort predisposed to early coronary artery disease due to past surgery involving coronary artery reimplantation...
Postoperative course in the cardiac intensive care unit following the first stage of Norwood reconstructionGil Wernovsky
Department of Pediatrics Division of Pediatric Cardiology, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Cardiol Young 17:652-65. 2007....
Rhythm and conduction disturbances at midterm follow-up after the ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Ann Thorac Surg 85:2072-8. 2008..To our knowledge, late electrophysiologic outcomes after the Ross procedure have not been described. The purpose of this study was to assess rhythm and conduction disturbances at midterm follow-up after the Ross procedure...
Parachute mitral valve: morphologic descriptors, associated lesions, and outcomes after biventricular repairBradley S Marino
Division of Cardiology in the Department of Pediatrics, Anesthesiology and Critical Care, and Surgery in the Cardiac Center at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Thorac Cardiovasc Surg 137:385-393.e4. 2009....
Extracorporeal membrane oxygenation after stage I reconstruction for hypoplastic left heart syndromeChitra Ravishankar
Division of Cardiology, The Children s Hospital of Philadelphia, PA 19104 4399, USA
Pediatr Crit Care Med 7:319-23. 2006..Our objective is to describe the outcome of "nonelective" ECMO after stage I reconstruction...
Predictors of poor weight gain in infants with a single ventricleJeffrey B Anderson
Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr 157:407-13, 413.e1. 2010..To assess growth from the time of neonatal discharge to the time of performance of the bidirectional Glenn (BDG) procedure in infants with a single ventricle and determine predictors of poor growth...
Exercise performance in children and adolescents after the Ross procedureBradley S Marino
Division of Cardiology, at the Cardiac Center of The Children's Hospital of Philadelphia, and the Department of Pediatrics at the University of Pennsylvania School of Medicine 19104, USA
Cardiol Young 16:40-7. 2006..CONCLUSIONS: In the majority of patients following the Ross procedure, exercise performance is stable and within the normal range of a healthy age and sex matched population, despite sedentary lifestyles and increased adiposity...
Evaluation of myocardial ischemia after surgical repair of anomalous aortic origin of a coronary artery in a series of pediatric patientsJulie A Brothers
Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
J Am Coll Cardiol 50:2078-82. 2007..We sought to prospectively evaluate evidence of myocardial ischemia after surgical repair of anomalous aortic origin of a coronary artery with an interarterial course (AAOCA)...
Aortic morphometry and microcephaly in hypoplastic left heart syndromeAmanda J Shillingford
Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Cardiol Young 17:189-95. 2007..Microcephaly was associated with a small ascending aorta, but not a small transverse aortic arch. Impairment of somatic growth may be an additional factor in the development of microcephaly in these neonates...
Risk factors for adverse outcomes after surgery on the systemic atrioventricular valve in 109 childrenMatthew J Gillespie
Division of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA
Cardiol Young 16:35-42. 2006
Cardiac rhythm devices in the pediatric population: utilization and complicationsRichard J Czosek
The Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Heart Rhythm 9:199-208. 2012..Cardiac rhythm devices are important in the management of pediatric patients with rhythm abnormalities, although factors driving utilization are poorly understood...
Weight change in infants with a functionally univentricular heart: from surgical intervention to hospital dischargeBarbara Medoff-Cooper
Department of Pediatrics, The Children s Hospital of Philadelphia and School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States of America
Cardiol Young 21:136-44. 2011..The purpose of this study was to assess the pattern of weight change from surgical intervention to home discharge and to determine predictors of poor growth in this population of infants with congenital cardiac disease...
Impact of oral sildenafil on exercise performance in children and young adults after the fontan operation: a randomized, double-blind, placebo-controlled, crossover trialDavid J Goldberg
Division of Cardiology, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
Circulation 123:1185-93. 2011..A medication capable of decreasing pulmonary vascular resistance should allow improved cardiac filling and improved exercise capacity...
Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricleJeffrey B Anderson
Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45259, USA
J Thorac Cardiovasc Surg 138:397-404.e1. 2009..We sought to assess the effect of nutritional status at the time of the bidirectional Glenn procedure on short-term outcomes...
Noninvasive risk stratification techniques in pediatric patients with ventricular preexcitationRichard J Czosek
Division of Pediatric Cardiology, Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Pacing Clin Electrophysiol 34:555-62. 2011..Individuals with ventricular preexcitation (VP) are known to have an increased risk of sudden death. This risk has been associated with conduction properties of the accessory pathway...
Utility of ambulatory monitoring in patients with congenital heart diseaseRichard J Czosek
Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
Am J Cardiol 111:723-30. 2013....
Impact of cardiac devices on the quality of life in pediatric patientsRichard J Czosek
Heart Institute, Division of Cardiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45208, USA
Circ Arrhythm Electrophysiol 5:1064-72. 2012..The purpose of this study was to compare (QOL) scores among pediatric device patients, healthy controls, and congenital heart disease (CHD) patients and determine the key drivers of QOL in pediatric device patients...
Obesity is a common comorbidity in children with congenital and acquired heart diseaseNelangi M Pinto
Division of Cardiology, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatrics 120:e1157-64. 2007..Many children with heart disease are sedentary as a result of physician-, parent-, and/or self-imposed restrictions. The aim of this study was to evaluate the impact of the epidemic of obesity on children with heart disease...
Usefulness of left ventricular inflow index to predict successful biventricular repair in right-dominant unbalanced atrioventricular canalAnita L Szwast
Division of Cardiology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Am J Cardiol 107:103-9. 2011..We propose incorporation of the LVII into the echocardiographic assessment of these patients...
Coronary artery pattern and age impact exercise performance late after the arterial switch operationSara K Pasquali
The Cardiac Center at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Thorac Cardiovasc Surg 134:1207-12. 2007..The purpose of this study was to evaluate the relationship between coronary artery pattern and exercise performance late after the arterial switch operation...
Corticosteroids and outcome in children undergoing congenital heart surgery: analysis of the Pediatric Health Information Systems databaseSara K Pasquali
Department of Pediatrics, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27715, USA
Circulation 122:2123-30. 2010..Children undergoing congenital heart surgery often receive corticosteroids with the aim of reducing the inflammatory response after cardiopulmonary bypass; however, the value of this approach is unclear...
Adherence to treatment among children with cardiac diseaseRichard F Ittenbach
Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Cardiol Young 19:545-51. 2009..Our purpose was to review the literature with respect to issues of adherence to treatment among children with congenital and acquired cardiac disease...
The effect of paediatric syncope on health-related quality of lifeJeffrey B Anderson
Department of Pediatrics, The Heart Institute, Cincinnati Children s Hospital Medical Center, Ohio, United States of America
Cardiol Young 22:583-8. 2012..Syncope is common in children and adolescents and most commonly represents neurocardiogenic syncope. No information has been reported regarding the effect of syncope on health-related quality of life in children...
Neo-aortic root dilation and valve regurgitation up to 21 years after staged reconstruction for hypoplastic left heart syndromeMeryl S Cohen
Department of Pediatrics, University of Pennsylvania School of Medicine, Cardiac Center at Children s Hospital of Philadelphia, 19104, USA
J Am Coll Cardiol 42:533-40. 2003..We sought to assess the prevalence and progression of neo-aortic root dilation and valvar regurgitation after staged reconstruction for hypoplastic left heart syndrome (HLHS)...
One slide fits all: the versatility of slide tracheoplasty with cardiopulmonary bypass support for airway reconstruction in childrenPeter B Manning
Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Thorac Cardiovasc Surg 141:155-61. 2011..This study describes results of tracheal reconstruction in children with slide tracheoplasty with cardiopulmonary bypass and identifies predictors for adverse outcomes...
Outcomes after the stage I reconstruction comparing the right ventricular to pulmonary artery conduit with the modified Blalock Taussig shuntSarah Tabbutt
Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Ann Thorac Surg 80:1582-90; discussion 1590-1. 2005..Recent reports advocate that a right ventricular to pulmonary artery (RV-PA) conduit improves outcome after the stage I reconstruction...
Off-label use of cardiovascular medications in children hospitalized with congenital and acquired heart diseaseSara K Pasquali
Division of Cardiology, Department of Pediatrics, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC 27715, USA
Circ Cardiovasc Qual Outcomes 1:74-83. 2008..Recent legislation has aimed to stimulate pediatric research and improve drug labeling. This study describes off-label use of CV medications in children hospitalized with congenital and acquired CV disease...
Tetrasomy 15q25.2→qter identified with SNP microarray in a patient with multiple anomalies including complex cardiovascular malformationJaya K George-Abraham
Division of Human Genetics, Department of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Am J Med Genet A 158:1971-6. 2012..Finally, we believe cardiac defects with this genetic syndrome are a poor prognostic finding associated with high mortality...
A fetus with hypertrophic cardiomyopathy, restrictive, and single-ventricle physiology, and a beta-myosin heavy chain mutationRobert B Hinton
Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr 157:164-6. 2010..We describe a patient with a pathogenic familial beta-myosin heavy chain mutation who was prenatally diagnosed with left ventricular hypoplasia and restrictive diastolic physiology...
Linear lesion cryoablation for the treatment of atrioventricular nodal re-entry tachycardia in pediatrics and young adultsRichard J Czosek
Heart Center, Department of Pediatrics, Division of Pediatric Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Pacing Clin Electrophysiol 33:1304-11. 2010..Cryothermal ablation reduces the risk of AV block, but has had decreased procedural success and increased recurrence of tachycardia. We sought to evaluate the technique of linear lesion cryoablation (LLC) for treatment of AVNRT...
Novel use of dexmedetomidine in a patient with pulmonary hypertensionAruna T Nathan
Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104 4399, USA
Paediatr Anaesth 18:782-4. 2008..This resulted in avoidance of endotracheal intubation and positive pressure ventilation, with subsequent recovery to discharge home...
Outcomes after the Fontan procedureBradley S Marino
Department of Pediatrics, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Curr Opin Pediatr 14:620-6. 2002....
Neo-aortic valvar function after the arterial switchBradley S Marino
Cardiac Center, Children s Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania School of Medicine, United States of America
Cardiol Young 16:481-9. 2006....
Is the Ross procedure as good as we thought it would be?Bradley S Marino
Divisione of Cardiology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
Cardiol Young 16:125-30. 2006
Health-related quality-of-life assessment after intensive care therapy: preexisting disease mattersBradley S Marino
Crit Care Med 33:1658-9. 2005
Research Grants
- Testing the Pediatric Cardiac Quality of Life InventoryBradley Marino; Fiscal Year: 2007..S. and the U.K. The proposed didactic and research experiences described will ensure that Dr. Marino becomes an independent physician scientist in the field of pediatric cardiovascular outcomes research. ..
