Research Topics
Genomes and GenesSpecies | Peter B ManningSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Publications
Slide tracheoplasty in infants and children: risk factors for prolonged postoperative ventilatory supportPeter B Manning
Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Ann Thorac Surg 85:1187-91; discussion 1191-2. 2008..A single-institution experience with slide tracheoplasty for management of tracheal stenosis in children with emphasis on identifying predictors of prolonged postoperative mechanical ventilation is reviewed...
One slide fits all: the versatility of slide tracheoplasty with cardiopulmonary bypass support for airway reconstruction in childrenPeter B Manning
Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Thorac Cardiovasc Surg 141:155-61. 2011..This study describes results of tracheal reconstruction in children with slide tracheoplasty with cardiopulmonary bypass and identifies predictors for adverse outcomes...
Aortic arch recoarctation after the Norwood stage I palliation: the comparative accuracy of blood pressure cuff and echocardiographic Doppler gradients in detecting significant obstructionPriya Sekar
Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Congenit Heart Dis 4:440-7. 2009..We sought to evaluate the ability of cuff BP and Doppler gradients, measured at routine outpatient clinic visits, to predict significant arch obstruction in single ventricle patients after the Norwood operation...
Factors affecting long-term risk of aortic arch recoarctation after the Norwood procedureTraci M Ashcraft
Division of Cardiothoracic Surgery, The Heart Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Ann Thorac Surg 85:1397-401; discussion 1401-2. 2008..The purpose of this study was to identify factors predicting risk of aortic arch recoarctation after the Norwood procedure...
Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypassJohn S Giuliano
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
Intensive Care Med 34:1851-7. 2008..The aim was to investigate the effects of cardiopulmonary bypass (CPB) on plasma levels of the vascular growth factors, angiopoietin (angpt)-1, angpt-2, and vascular endothelial growth factor (VEGF)...
Combined steroid treatment for congenital heart surgery improves oxygen delivery and reduces postbypass inflammatory mediator expressionValerie A Schroeder
Division of Cardiology, Cincinnati Children's Hospital, Cincinnati, Ohio, USA
Circulation 107:2823-8. 2003..These findings need to be confirmed in a larger multicenter trial...
Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operationDerek S Wheeler
Divisions of Critical Care Medicine, Cardiology, and Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Cardiol Young 18:41-50. 2008..In addition, based on these results, our practice has evolved to initiate enteral feedings in the preoperative period if feasible, with such enteral feedings resumed as soon as possible following surgery...
Compression of an extracardiac fontan following classic fontan revisionJefferson M Lyons
Department of Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Card Surg 19:254-7. 2004..We report this complication and suggest ringed conduits to be considered to avoid the possibility of external compression...
Risk of recoarctation should not be a deciding factor in the timing of coarctation repairJeffrey M Pearl
Division of Pediatric Cardiothoracic Surgery, Children s Hospital Medical Center, and the Department of Surgery, University of Cincinnati, Cincinnati, Ohio 45229, USA
Am J Cardiol 93:803-5. 2004..At a mean follow-up of 44.4 months, there have were no late reoperations, and 2 patients required balloon aortoplasty. The overall incidence of late reintervention was 1.7%, with only 2.4% (2 of 83) in those <1 year old...
Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplastyJenni Raake
Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Respir Care 56:1198-202. 2011..This strategy of ECMO with extubation, then high-frequency oscillatory ventilation is a useful rescue therapy in patients with postoperative tracheal dehiscence...
Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapyMai T Nguyen
Department of Pediatrics, Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Pediatr Nephrol 23:1317-26. 2008..We concluded that urinary aprotinin levels 2 h after initiation of CPB predict the development of AKI and adverse clinical outcomes...
Slide tracheoplasty for the management of complete tracheal ringsMichael J Rutter
Departments of Pediatric Otolaryngology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA
J Pediatr Surg 38:928-34. 2003..CONCLUSIONS: Our management of complete tracheal rings has evolved over the last decade, and slide tracheoplasty currently is our preferred surgical approach for tracheal stenosis regardless of the length of narrowing...
Postoperative assessment of laryngopharyngeal dysfunction in neonates after Norwood operationKonstantin Averin
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Ann Thorac Surg 94:1257-61. 2012..The purpose of this study was to evaluate the incidence of vocal cord (VC) and swallowing dysfunction in infants after the Norwood operation and to examine the relationship between laryngopharyngeal dysfunction and postoperative outcomes...
Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertensionJeffrey M Pearl
Division of Cardiothoracic Surgery, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Crit Care Med 30:89-93. 2002..The objective of this study was to determine whether iNO therapy alters plasma ET-1 levels...
Unilateral pulmonary edema and acute rheumatic feverJohn S Giuliano
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Eur J Pediatr 167:465-7. 2008..We present a case of an 8-year-old child who presented with unilateral pulmonary edema secondary to acute mitral insufficiency due to ARF. ARF should be considered in the differential diagnosis of unilateral pulmonary edema in children...
Heparin-induced thrombocytopenia complicating support by the Berlin HeartPirooz Eghtesady
Division of Pediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
ASAIO J 51:820-5. 2005..We discuss the unique challenges posed by HIT II complicating pediatric VAD support and in relation to the heparin coating of the device...
Early failure of the Shelhigh pulmonary valve conduit in infantsJeffrey M Pearl
Department of Pediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Ohio 45229, USA
Ann Thorac Surg 74:542-8; discussion 548-9. 2002..The Shelhigh porcine-valved conduit (SPVC) with its No-React anticalcification properties was developed as a potential alternative to homografts...
Biventricular repair after Norwood palliationJeffrey M Pearl
Department of Pediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, OSB 3, Cincinnati, OH 45229, USA
Ann Thorac Surg 75:132-6; discussion 136-7. 2003..Additionally, echocardiographic data were reviewed in an attempt to develop objective prognostic criteria for selection of patients suitable for BVR...
Pancreatitis in Fontan patients is related to impaired ventricular relaxationAitizaz U Syed
Department of Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229-3039, USA
Ann Thorac Surg 75:153-7; discussion 157. 2003..Evaluation of preoperative diastolic function in these patients may provide additional insights in to clinical outcome following the Fontan procedure...
First-stage palliation for hypoplastic left heart syndrome in the twenty-first centuryJeffrey M Pearl
Division of Pediatric Cardiothoracic Surgery, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Ann Thorac Surg 73:331-9; discussion 339-40. 2002..This review describes and discusses the current surgical and medical management of patients undergoing first-stage palliation for hypoplastic left heart syndrome and its variants...
Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditisMichael T Bigham
Department of Pediatrics, Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Pediatr Crit Care Med 9:e1-4. 2008..To describe a young child with complex fibropurulent pericarditis who was successfully treated with intrapericardial recombinant tissue plasminogen activator...
Left ventricular noncompaction cardiomyopathy in barth syndrome: an example of an undulating cardiac phenotype necessitating mechanical circulatory support as a bridge to transplantationSamuel P Hanke
Heart Institute, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue ML 2003, Cincinnati, OH 45213, USA
Pediatr Cardiol 33:1430-4. 2012..Here we discuss the management of a child with BTHS using mechanical circulatory support and describe the use of an in-line oxygenator, Quadrox, with the Berlin Excor device...
Extracellular matrix remodeling and organization in developing and diseased aortic valvesRobert B Hinton
Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA
Circ Res 98:1431-8. 2006....
Effect of superior cavopulmonary anastomosis on the rate of tricuspid annulus dilation in hypoplastic left heart syndromeErik C Michelfelder
Division of Cardiology, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
Am J Cardiol 89:96-8. 2002
Determinants of mortality and type of repair in neonates with pulmonary atresia and intact ventricular septumDavid A Ashburn
Division of Cardiothoracic Surgery, Hospital for Sick Children, Toronto, Onario, Canada
J Thorac Cardiovasc Surg 127:1000-7; discussion 1007-8. 2004..In the current era, 85% of neonates are likely to reach a definitive surgical end point, with 2-ventricle repair achieved in an estimated 50%...
Impaired systemic ventricular relaxation affects postoperative short-term outcome in Fontan patientsWilliam L Border
Division of Cardiology, Cincinnati Children's Hospital Medical Center, Ohio 45229-3039, USA
J Thorac Cardiovasc Surg 126:1760-4. 2003..This illustrates the importance of systemic ventricular relaxation and highlights the need for a more comprehensive assessment of diastolic function before the Fontan operation...
The use of the Shelhigh porcine valve conduit in infantsJeffrey M Pearl
Ann Thorac Surg 73:697-8. 2002
