Research Topics
Genomes and Genes | Elizabeth A MannSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Prevalence of mutations in hepatitis C virus core protein associated with alteration of NF-kappaB activationElizabeth A Mann
Department of Internal Medicine, Division of Digestive Diseases, University of Cincinnati, 231 Albert B Sabin Way, OH 55267 0595, USA
Virus Res 121:51-7. 2006..Further studies are needed to assess potential associations between specific amino acid substitutions at positions 9-11 and liver disease progression and/or response to treatment in individual patients...
Lack of guanylate cyclase C results in increased mortality in mice following liver injuryElizabeth A Mann
Division of Gastroenterology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati, Cincinnati, OH, USA
BMC Gastroenterol 10:86. 2010..In the adult rat liver, GC-C expression is increased in response to injury. We hypothesized that GC-C is required for repair/recovery from liver injury...
Gastrointestinal infection as a trigger for inflammatory bowel diseaseElizabeth A Mann
Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Curr Opin Gastroenterol 28:24-9. 2012..This review focuses on the current findings on the role of gastrointestinal pathogens in the cause of chronic inflammatory bowel disease...
Murine guanylate cyclase C regulates colonic injury and inflammationKris A Steinbrecher
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
J Immunol 186:7205-14. 2011..These findings demonstrate a novel role for GC-C signaling in facilitating mucosal wounding and inflammation, and further suggest that this may be mediated, in part, through control of RELMβ production...
Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptorStephen L Carrithers
Department of Internal Medicine, Division of Infectious Diseases, Lexington VA Medical Center and University of Kentucky, Lexington, Kentucky 40506, USA
Kidney Int 65:40-53. 2004..However, the in vivo consequences of GN, UGN, and STa on renal function and their mechanism of action have yet to be rigorously tested...
Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse modelElizabeth A Mann
Division of Digestive Diseases, VA Medical Center and University of Cincinnati, Cincinnati, OH 45267, USA
Int J Cancer 116:500-5. 2005..We propose that these alterations are a possible compensatory mechanism by which loss of GC-C signaling also affects tumorigenesis...
Clostridium difficile infection and treatment in the pediatric inflammatory bowel disease populationEthan Mezoff
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr Gastroenterol Nutr 52:437-41. 2011..In addition, the effectiveness of antimicrobial therapies has been questioned. Our aim was to estimate the incidence of CDAD in a pediatric IBD population and review treatment efficacy...
E. coli heat-stable enterotoxin and guanylyl cyclase C: new functions and unsuspected actionsRalph A Giannella
Division of Digestive Diseases, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0595, USA
Trans Am Clin Climatol Assoc 114:67-85; discussion 85-6. 2003....
