Rohit Kohli

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities
    Rohit Kohli
    Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, USA
    Am J Physiol Gastrointest Liver Physiol 299:G652-60. 2010
  2. ncbi High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis
    Rohit Kohli
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Hepatology 52:934-44. 2010
  3. ncbi Molecular insights from bariatric surgery
    Rohit Kohli
    Division of Gastroenterology, Hepatology, and Nutrition, MLC 2010, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, OH 45229, USA
    Rev Endocr Metab Disord 12:211-7. 2011
  4. ncbi Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats
    Karen K Ryan
    The University of Cincinnati College of Medicine, Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Cincinnati, OH 45237, USA
    Endocrinology 154:9-15. 2013
  5. ncbi Insulin concentration modulates hepatic lipid accumulation in mice in part via transcriptional regulation of fatty acid transport proteins
    Samir Softic
    Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 7:e38952. 2012
  6. ncbi The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition
    Shrawan Gaitonde
    Department of Surgery, University Hospital University of Cincinnati, Cincinnati, Ohio 45267, USA
    J Surg Res 178:33-9. 2012
  7. ncbi Advances in the surgical treatment of morbid obesity
    Margaret A Stefater
    Division of Pediatric and Thoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, United States
    Mol Aspects Med 34:84-94. 2013
  8. ncbi Isolated unilateral cytomegalovirus retinitis: a rare long-term complication after pediatric liver transplantation
    James E Squires
    Pediatric Liver Care Center, Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatr Transplant 17:E16-9. 2013
  9. ncbi Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway
    Rohit Kohli
    Department of Pediatrics, Children s Memorial Hospital, Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614, USA
    J Biol Chem 282:21327-36. 2007
  10. ncbi Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium
    Atul Sahai
    Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children's Memorial Research Center, Chicago, IL 60614, USA
    Am J Physiol Gastrointest Liver Physiol 291:G55-62. 2006

Collaborators

Detail Information

Publications10

  1. ncbi Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities
    Rohit Kohli
    Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, USA
    Am J Physiol Gastrointest Liver Physiol 299:G652-60. 2010
    ..Changes in serum bile acids or bile acid enterohepatic recycling may mediate the metabolic benefits seen after bariatric surgery...
  2. ncbi High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis
    Rohit Kohli
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Hepatology 52:934-44. 2010
    ....
  3. ncbi Molecular insights from bariatric surgery
    Rohit Kohli
    Division of Gastroenterology, Hepatology, and Nutrition, MLC 2010, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, OH 45229, USA
    Rev Endocr Metab Disord 12:211-7. 2011
    ..We will also discuss existing literature regarding the weight-loss-independent metabolic benefits including improvement in insulin sensitivity and central nervous system integration of these signals...
  4. ncbi Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats
    Karen K Ryan
    The University of Cincinnati College of Medicine, Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Cincinnati, OH 45237, USA
    Endocrinology 154:9-15. 2013
    ..Together, these findings identify the central nervous system as a potentially important target for the beneficial effects of FGF19 in the treatment of obesity and diabetes...
  5. ncbi Insulin concentration modulates hepatic lipid accumulation in mice in part via transcriptional regulation of fatty acid transport proteins
    Samir Softic
    Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 7:e38952. 2012
    ..Thus, we asked whether insulin is an independent modulator of hepatic lipid accumulation...
  6. ncbi The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition
    Shrawan Gaitonde
    Department of Surgery, University Hospital University of Cincinnati, Cincinnati, Ohio 45267, USA
    J Surg Res 178:33-9. 2012
    ..Ileal transposition involves a short segment of distal ileum being transposed to the proximal jejunum in an isoperistaltic direction, thereby avoiding any gastric resection or intestinal bypass...
  7. ncbi Advances in the surgical treatment of morbid obesity
    Margaret A Stefater
    Division of Pediatric and Thoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, United States
    Mol Aspects Med 34:84-94. 2013
    ..This may position VSG as an increasingly important procedure, particularly for the treatment of pediatric obesity...
  8. ncbi Isolated unilateral cytomegalovirus retinitis: a rare long-term complication after pediatric liver transplantation
    James E Squires
    Pediatric Liver Care Center, Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatr Transplant 17:E16-9. 2013
    ..Currently, there is no standard of care regarding screening for CMV retinitis, and thus, further research is needed to define the need for potential changes in current clinical practices and post-transplant screening protocols...
  9. ncbi Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway
    Rohit Kohli
    Department of Pediatrics, Children s Memorial Hospital, Children s Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60614, USA
    J Biol Chem 282:21327-36. 2007
    ..Our findings suggest a common path for response to altered nutrition involving mitochondrial ROS-dependent PI 3-kinase pathway regulation, leading to steatosis...
  10. ncbi Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium
    Atul Sahai
    Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children's Memorial Research Center, Chicago, IL 60614, USA
    Am J Physiol Gastrointest Liver Physiol 291:G55-62. 2006
    ..PI3-kinase plays a central role in signaling the MCD medium-induced steatosis and increased OPN expression, whereas OPN appears to play a role in signaling hepatocyte ALT release but not steatosis...