JONATHAN DAVID contact KATZ

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system
    John J Hutton
    Department of Pediatrics and Biomedical Informatics, University of Cincinnati and Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio 45229, USA
    BMC Genomics 5:82. 2004
  2. pmc Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes
    Jonathan D Katz
    Division of Endocrinology, Diabetes Research Center, Cincinnati Children s Research Foundation, Cincinnati, OH 45229, USA
    J Immunol 185:1999-2003. 2010
  3. doi request reprint Breaking T cell tolerance to beta cell antigens by merocytic dendritic cells
    Jonathan D Katz
    Division of Endocrinology, Department of Pediatrics, Cincinnati Children s Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Cell Mol Life Sci 68:2873-83. 2011

Research Grants

  1. Dissecting Dendritic Cell Function in Autoimmune Diabetes
    Jonathan Katz; Fiscal Year: 2009
  2. The Insulitis Reporter Mouse
    Jonathan Katz; Fiscal Year: 2007
  3. Dissecting Dendritic Cell Function in Autoimmune Diabetes
    JONATHAN DAVID KATZ; Fiscal Year: 2010
  4. Dendritic Cells in the Breaking of Peripheral Tolerance in Type 1 Diabetes
    JONATHAN DAVID contact KATZ; Fiscal Year: 2010
  5. Using Genomics to Understand Autoimmune Diabetes
    Jonathan Katz; Fiscal Year: 2006

Collaborators

Detail Information

Publications3

  1. pmc Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system
    John J Hutton
    Department of Pediatrics and Biomedical Informatics, University of Cincinnati and Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio 45229, USA
    BMC Genomics 5:82. 2004
    ..Using expression pattern criteria, we identified 360 genes with preferential expression in thymus, spleen, peripheral blood mononuclear cells, lymph nodes (unstimulated or stimulated), or in vitro activated T-cells...
  2. pmc Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes
    Jonathan D Katz
    Division of Endocrinology, Diabetes Research Center, Cincinnati Children s Research Foundation, Cincinnati, OH 45229, USA
    J Immunol 185:1999-2003. 2010
    ..Thus, the mcDC subset appears to represent the long-sought APC responsible for breaking peripheral tolerance to beta cell Ags in vivo...
  3. doi request reprint Breaking T cell tolerance to beta cell antigens by merocytic dendritic cells
    Jonathan D Katz
    Division of Endocrinology, Department of Pediatrics, Cincinnati Children s Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Cell Mol Life Sci 68:2873-83. 2011
    ..Thus, the mcDC subset appears to represent the long-sought critical antigen-presenting cell responsible for breaking peripheral tolerance to beta cell antigen in vivo...

Research Grants9

  1. Dissecting Dendritic Cell Function in Autoimmune Diabetes
    Jonathan Katz; Fiscal Year: 2009
    ..Aim 2: To determine if NKT cell-produced INF-9 and pDC-produced IDO establish a regulatory circuit that controls diabetogenic T cells in vivo. ..
  2. The Insulitis Reporter Mouse
    Jonathan Katz; Fiscal Year: 2007
    ..Specific Aim 2: To validate the specificity and sensitivity of the insulitis reporter NOD mice by qualitative analysis of sHPAP expression and documented insulitis in NOD mice. ..
  3. Dissecting Dendritic Cell Function in Autoimmune Diabetes
    JONATHAN DAVID KATZ; Fiscal Year: 2010
    ..Aim 2: To determine if NKT cell-produced INF-9 and pDC-produced IDO establish a regulatory circuit that controls diabetogenic T cells in vivo. ..
  4. Dendritic Cells in the Breaking of Peripheral Tolerance in Type 1 Diabetes
    JONATHAN DAVID contact KATZ; Fiscal Year: 2010
    ....
  5. Using Genomics to Understand Autoimmune Diabetes
    Jonathan Katz; Fiscal Year: 2006
    ..Aim 3: To establish the differential gene expression pattern associated with disease progression and resistance in NOD recipients of islet-reactive Th1 and Th2 T cells. ..