Research Topics
| Thomas IngeSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Publications
Baseline BMI is a strong predictor of nadir BMI after adolescent gastric bypassThomas H Inge
Division of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Pediatr 156:103-108.e1. 2010..Surgical treatment of extreme obesity may be appropriate for some adolescents. We hypothesized that surgical weight loss outcomes may differ by preoperative level of extreme obesity (body mass index [BMI] > or=99th percentile)...
Managing bariatric patients in a children's hospital: radiologic considerations and limitationsThomas H Inge
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Pediatr Surg 40:609-17. 2005..Herein the authors discuss these topics within the context of characteristic bariatric patient profiles and the Roux-en-Y gastric bypass procedure, currently the authors' standard operative approach...- Surgical approach to adolescent obesityThomas H Inge
Department of Surgery, Division of Pediatric Surgery, University of Cincinnati, Cincinnati, OH, USA
Adolesc Med Clin 15:429-53. 2004..Indications for operation during adolescence should be conservative until appropriately designed clinical studies have demonstrated the safety and efficacy of these techniques applied to adolescents... 
Challenges of adolescent bariatric surgery: tips for managing the extremely obese teenThomas Inge
Department of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Laparoendosc Adv Surg Tech A 18:157-69. 2008..Finally, the views and opinions expressed in this paper reflect the balanced examination of various issues related to pediatric bariatric surgery by the presenters but do not necessarily represent the opinions of the IPEG organization...- WP744 is a novel anthracycline with enhanced activity against neuroblastomaThomas H Inge
Children s Hospital Research Foundation, Department of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Surg Res 121:187-96. 2004..Two analogs, WP744 and WP769, were selected and their biological properties were compared with Dox and the daunorubicin-based bisintercalator WP631. These novel Dox analogs may have antitumor activity beyond MDR evasion... - Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescentsThomas H Inge
Division of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Pediatrics 123:214-22. 2009..We hypothesized that gastric bypass would improve parameters of metabolic dysfunction and cardiovascular risk in adolescents with type 2 diabetes mellitus... - Bariatric surgery for severely overweight adolescents: concerns and recommendationsThomas H Inge
Department of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
Pediatrics 114:217-23. 2004..Surgery should be performed in institutions that are equipped to meet the tertiary care needs of severely obese patients and to collect long-term data on the clinical outcomes of these patients... - Bariatric surgery for pediatric extreme obesity: now or later?T H Inge
Division of Pediatric and Thoracic Surgery, Comprehensive Weight Management Program, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA
Int J Obes (Lond) 31:1-14. 2007.... - Bariatric surgery for morbidly obese adolescents: is there a rationale for early intervention?Thomas H Inge
Division of Pediatric General and Thoracic Surgery, Comprehensive Weight Management Center, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, OSB 3320, Cincinnati, OH 45229 3039, USA
Growth Horm IGF Res 16:S15-9. 2006..In this paper, the indications, contraindications, and early surgical outcomes of gastric bypass surgery for morbidly obese adolescents are reviewed, and important directions for future research are discussed... - Gastric bypass surgery for treatment of hypothalamic obesity after craniopharyngioma therapyThomas H Inge
Division of Pediatric General and Thoracic Surgery, ML 2023, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Nat Clin Pract Endocrinol Metab 3:606-9. 2007..Extreme obesity (BMI >60 kg/m(2)) and hyperinsulinemia followed tumor resection and cranial irradiation. Dietary interventions were unsuccessful, and pharmacologic intervention (i.e. octreotide) only slowed the rate of weight gain... - Childhood obesity--a problem of surgical proportions?Thomas H Inge
Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2023, Cincinnati, OH 45229 3039, USA
Nat Clin Pract Gastroenterol Hepatol 5:180-1. 2008 - Preferential loss of central (trunk) adiposity in adolescents and young adults after laparoscopic gastric bypassThomas Inge
Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Surg Obes Relat Dis 3:153-8. 2007.... - Obesity identified by discharge ICD-9 codes underestimates the true prevalence of obesity in hospitalized childrenJessica G Woo
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Pediatr 154:327-31. 2009..To define inpatient care of obese children with or without an obesity diagnosis... - Application of laparoscopy for bariatric surgery in adolescentsVictor F Garcia
University of Cincinnati College of Medicine, Ohio, USA
Curr Opin Pediatr 15:248-55. 2003.... - Obstructive sleep apnea in extremely overweight adolescents undergoing bariatric surgeryManinder Kalra
Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Obes Res 13:1175-9. 2005..To determine the prevalence of obstructive sleep apnea (OSA) in extremely overweight adolescents and to examine the effect of significant weight loss on OSA severity... - Effect of surgical weight loss on sleep architecture in adolescents with severe obesityM Kalra
Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Obes Surg 18:675-9. 2008..Weight loss results in resolution of obesity-associated morbidity. Our aim was to determine the effect of weight loss on sleep architecture in adolescents with severe obesity... - Histologic spectrum of nonalcoholic fatty liver disease in morbidly obese adolescentsStavra Xanthakos
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA
Clin Gastroenterol Hepatol 4:226-32. 2006..These findings might support use of a modified scoring system for pediatric NASH. Presence of the metabolic syndrome in morbidly obese adolescents did not distinguish NASH from steatosis alone... - How young for bariatric surgery in children?Allen F Browne
Division of Pediatric Surgery, Nationwide Children s Hospital, Columbus, Ohio 43206, USA
Semin Pediatr Surg 18:176-85. 2009..This will require the combined efforts of the pediatric health care providers from many specialties and partnerships with industry to facilitate discovery and implementation... - Bariatric surgery and adolescent gynecologyRachel J Miller
Division of Adolescent Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Curr Opin Obstet Gynecol 19:427-33. 2007..This review summarizes the impact of bariatric surgery on gynecologic complications in the context of the extremely obese adolescent and reviews contraceptive considerations before and after adolescent bariatric surgery... - Pregnancy after gastric bypass surgery in adolescentsHelmut R Roehrig
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
Obes Surg 17:873-7. 2007..There is no previous research or documentation of the incidence of pregnancy or pregnancy outcomes in female adolescents after undergoing bariatric surgery... - Best practice updates for pediatric/adolescent weight loss surgeryJaney S A Pratt
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
Obesity (Silver Spring) 17:901-10. 2009.... - Weight-specific health-related quality of life in adolescents with extreme obesityAvani C Modi
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Obesity (Silver Spring) 16:2266-71. 2008..Overall, these data suggest that HRQOL is not homogenous in adolescents with extreme obesity... - Reversibility of cardiac abnormalities in morbidly obese adolescentsHolly M Ippisch
Division of Cardiology, Cincinnati Children s Hospital, Medical Center and Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229, USA
J Am Coll Cardiol 51:1342-8. 2008..The purpose of this study was to evaluate changes in cardiac geometry, systolic and diastolic function before and after weight loss in morbidly obese adolescents... - One-year outcomes of Roux-en-Y gastric bypass for morbidly obese adolescents: a multicenter study from the Pediatric Bariatric Study GroupM Louise Lawson
Center for Epidemiology and Biostatistics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45255, USA
J Pediatr Surg 41:137-43; discussion 137-43. 2006..Although there are considerable risks of bariatric surgery, early experience suggests that risks are offset by health benefits... - Health-related quality of life and depressive symptoms in adolescents with extreme obesity presenting for bariatric surgeryMeg H Zeller
Division of Behavioral Medicine and Clinical Psychology, College of Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
Pediatrics 117:1155-61. 2006..We sought to document health-related quality of life (HRQoL) impairment and depressive symptomatology in adolescents with extreme obesity considering surgical weight loss... - A critical appraisal of evidence supporting a bariatric surgical approach to weight management for adolescentsThomas H Inge
Division of Pediatric General and Thoracic Surgery, Center for Epidemiology and Biostatistics, University of Cincinnati, Cincinnati, OH, USA
J Pediatr 147:10-9. 2005 - Bariatric surgery in adolescents: an updateStavra A Xanthakos
Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, ML 2010, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
Adolesc Med Clin 17:589-612; abstract x. 2006..Data on the complications and outcomes of bariatric surgery in this special population are reviewed... - Psychosocial functioning improves following adolescent bariatric surgeryMeg H Zeller
Division of Behavioral Medicine and Clinical Psychology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Obesity (Silver Spring) 17:985-90. 2009..Longer-term follow-up will be critical to determine adolescent weight and psychosocial trajectories, their interrelations, and what role psychosocial status plays in continued weight loss, maintenance, and regain... - Nutritional consequences of bariatric surgeryStavra A Xanthakos
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Ohio 45229 3039, USA
Curr Opin Clin Nutr Metab Care 9:489-96. 2006.... - Changes in depressive symptoms among adolescent bariatric candidates from preoperative psychological evaluation to immediately before surgeryMegan B Ratcliff
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children s Hospital Medical Center, Cinncinnati, Ohio 45229, USA
Surg Obes Relat Dis 7:50-4. 2011..The present study examined whether adolescent depressive symptoms among bariatric candidates change during preoperative preparation compared with adolescents with extreme obesity who were not seeking surgery... - Intraoperative manometry during laparoscopic Heller myotomy improves outcome in pediatric achalasiaMubeen Jafri
Department of Pediatric and Thoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr Surg 43:66-70; discussion 70. 2008..Intraoperative esophageal manometry has been used to ensure adequacy of myotomies in adults. The purpose of the present study was to review our experience in the management of children with achalasia... - Nuclear factor-kappa B and apoptosis inducing factor activation by doxorubicin analog WP744 in SH-SY5Y neuroblastoma cellsJianqiang Wu
Department of Pediatric Surgery and Children's Hospital Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Surg Res 122:231-9. 2004..Enhanced cytotoxicity of this novel drug compared with Dox may be related to more effective activation of NF-kappaB and apoptosis-inducing factor in tumor cells... - A multidisciplinary approach to the adolescent bariatric surgical patientThomas H Inge
Department of Pediatric Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr Surg 39:442-7; discussion 446-7. 2004..Results have been satisfactory and justify a clinical trial to confirm the safety and efficacy of bariatric surgery in the adolescent population... - Adolescent paraplegia, morbid obesity, and pickwickian syndrome: outcome of gastric bypass surgeryGo Miyano
Department of Pediatric General and Thoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Pediatr Surg 44:e41-4. 2009..This case illustrates that paraplegia does not necessarily impair either weight loss efficacy or comorbidity resolution after Roux-en-Y gastric bypass surgery... - Treatment considerations for severe adolescent obesityThomas H Inge
Department of Pediatric Surgery, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
Surg Obes Relat Dis 1:133-9. 2005 - Cost analysis of ligature versus stapling techniques of laparoscopic appendectomy in childrenWilliam E Wehrman
Department of Pediatric General and Thoracic Surgery, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
J Laparoendosc Adv Surg Tech A 17:371-4. 2007..In light of the pressures for cost containment, we evaluated data from both laparoscopic methods to determine which was more effective based on cost and patient outcomes... - The combined effects of balloon valvuloplasty and surgical weight loss in treatment of aortic stenosisChristopher M Tangren
Department of Pediatric General and Thoracic Surgery, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
J Pediatr Surg 42:1443-5. 2007..She dramatically improved after the combined use of balloon valvuloplasty and Roux en Y gastric bypass. Gastric bypass surgery has promise for patients with congenital cardiac disease whose treatment is complicated by extreme obesity... - Importance of Sp1 consensus motifs in the MYCN promoterThomas H Inge
Children s Hospital Research Foundation and Department of Pediatric Surgery, Cincinnati Children s Hospital Medical Center, Ohio 45229, USA
Surgery 132:232-8. 2002..This region contains two GC-rich motifs and a CT box, regions for potential transcription factor interaction... - Attitudes of bariatric surgeons concerning adolescent bariatric surgery (ABS)Steven R Allen
Department of Pediatric Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA
Obes Surg 15:1192-5. 2005..Rigorous evaluation of the outcomes of this intervention with detailed prospective data collection is needed to support decision-making regarding use of bariatric surgery for adolescents with morbid obesity... - The effect of a right-sided aortic arch on outcome in children with esophageal atresia and tracheoesophageal fistulaSteven R Allen
Division of Pediatric and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr Surg 41:479-83. 2006..Therefore, careful diagnostic evaluation of a patient with an aortic arch that cannot be easily defined by ECHO should be considered before definitive repair... - A view from down under: laparoscopic look at a subrectus pacemakerMichael R Epstein
Divisions of Cardiology and Pediatric Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Pacing Clin Electrophysiol 25:1662-3. 2002..A photograph taken within the peritoneal cavity provides a unique view of the patient's subrectus pulse generator... - Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgeryThomas H Inge
J Pediatr Surg 42:1969-71. 2007 - Beriberi after gastric bypass surgery in adolescenceAlexander Towbin
Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
J Pediatr 145:263-7. 2004..We report three cases of dry beriberi in adolescents who underwent gastric bypass surgery for clinically severe obesity. The key to successful treatment of this problem lies in prompt recognition and thiamine supplementation... - Adolescent obesity and bariatric surgeryMichael A Helmrath
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Texas Children's Hospital Clinical Care Center, Suite 650, 6621 Fannin, Houston, TX 77030, USA
Surg Clin North Am 86:441-54, x. 2006 - Extreme pediatric obesity: weighing the health dangersStavra A Xanthakos
J Pediatr 150:3-5. 2007
Research Grants
- Adolescent Gastric By-Pass and Diabetic PrecursorsThomas Inge; Fiscal Year: 2006....
- Adolescent Bariatrics: Assessing Health Benefits & RisksThomas Inge; Fiscal Year: 2007....