John B Hogenesch


Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA


  1. Wu G, Ruben M, Schmidt R, Francey L, Smith D, Anafi R, et al. Population-level rhythms in human skin with implications for circadian medicine. Proc Natl Acad Sci U S A. 2018;115:12313-12318 pubmed publisher
    ..In summary, we show rhythms in human epidermis that persist at the population scale and describe a path to develop robust single-sample circadian biomarkers. ..
  2. Ruben M, Wu G, Smith D, Schmidt R, Francey L, Lee Y, et al. A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine. Sci Transl Med. 2018;10: pubmed publisher
    ..These results provide a useful resource for studying the role of circadian rhythms in medicine and support the idea that biological time might play a role in determining drug response. ..
  3. Krishnaiah S, Wu G, Altman B, Growe J, Rhoades S, Coldren F, et al. Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metab. 2017;25:961-974.e4 pubmed publisher
    ..These results provide the first comprehensive views of circadian liver and cell-autonomous metabolism. ..
  4. Ruben M, Hogenesch J. Circadian Rhythms: Move Over Neurons - Astrocytes Mediate SCN Clock Function. Curr Biol. 2017;27:R350-R352 pubmed publisher
    ..However, a series of recent studies demonstrate the importance of another cell type, astrocytes, for biological timekeeping. ..