Noah H Hillman

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi Moderate tidal volumes and oxygen exposure during initiation of ventilation in preterm fetal sheep
    Noah H Hillman
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Ohio, USA
    Pediatr Res 72:593-9. 2012
  2. ncbi Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, Cincinnati, OH 45236, USA
    Respir Res 11:151. 2010
  3. ncbi Inflammation and lung maturation from stretch injury in preterm fetal sheep
    Noah H Hillman
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Ohio 45229 3039, USA
    Am J Physiol Lung Cell Mol Physiol 300:L232-41. 2011
  4. ncbi Antenatal and postnatal corticosteroid and resuscitation induced lung injury in preterm sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, Cincinnati, OH 45236, USA
    Respir Res 10:124. 2009
  5. ncbi Airway injury from initiating ventilation in preterm sheep
    Noah H Hillman
    Division of Pulmonary Biology, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Pediatr Res 67:60-5. 2010
  6. ncbi Positive end-expiratory pressure and surfactant decrease lung injury during initiation of ventilation in fetal sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Am J Physiol Lung Cell Mol Physiol 301:L712-20. 2011
  7. ncbi Interleukin-1 in lipopolysaccharide induced chorioamnionitis in the fetal sheep
    Clare A Berry
    Division of Pulmonary Biology Neonatology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Reprod Sci 18:1092-102. 2011
  8. ncbi Pulmonary and systemic expression of monocyte chemotactic proteins in preterm sheep fetuses exposed to lipopolysaccharide-induced chorioamnionitis
    Tushar A Shah
    Divisions of Neonatology and Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Pediatr Res 68:210-5. 2010
  9. ncbi High and low body temperature during the initiation of ventilation for near-term lambs
    Molly K Ball
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Resuscitation 80:133-7. 2009
  10. ncbi Toll-like receptors and agonist responses in the developing fetal sheep lung
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Pediatr Res 63:388-93. 2008

Detail Information

Publications15

  1. ncbi Moderate tidal volumes and oxygen exposure during initiation of ventilation in preterm fetal sheep
    Noah H Hillman
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Ohio, USA
    Pediatr Res 72:593-9. 2012
    ..Exposure to large tidal volumes (V(T)s) at birth causes lung inflammation, and oxygen may amplify the injury. We hypothesized that normal V(T) ventilation at birth causes lung injury that is exacerbated by 95% oxygen...
  2. ncbi Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, Cincinnati, OH 45236, USA
    Respir Res 11:151. 2010
    ..Increased pro-inflammatory cytokines in tracheal aspirates correlate with the development of BPD in preterm infants. Ventilation of preterm lambs increases pro-inflammatory cytokines and causes lung inflammation...
  3. ncbi Inflammation and lung maturation from stretch injury in preterm fetal sheep
    Noah H Hillman
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Ohio 45229 3039, USA
    Am J Physiol Lung Cell Mol Physiol 300:L232-41. 2011
    ..We conclude that a brief period of high V(T) ventilation causes a proinflammatory cascade, a maturation of lung monocytic cells, and an induction of surfactant protein mRNA...
  4. ncbi Antenatal and postnatal corticosteroid and resuscitation induced lung injury in preterm sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, Cincinnati, OH 45236, USA
    Respir Res 10:124. 2009
    ..Antenatal corticosteroids mature the lungs of preterm infants and postnatal corticosteroids are used to treat bronchopulmonary dysplasia...
  5. ncbi Airway injury from initiating ventilation in preterm sheep
    Noah H Hillman
    Division of Pulmonary Biology, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Pediatr Res 67:60-5. 2010
    ..HSP70 protein decreased in the lung tissue and increased in BALF with ventilation. Initiation of ventilation induced a stress response and inflammatory cytokines in small and medium-sized airways...
  6. ncbi Positive end-expiratory pressure and surfactant decrease lung injury during initiation of ventilation in fetal sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Am J Physiol Lung Cell Mol Physiol 301:L712-20. 2011
    ..The use of PEEP during initiation of ventilation at birth decreased early mediators of lung injury. Surfactant administration changed the distribution of injury and had a moderate additive protective effect...
  7. ncbi Interleukin-1 in lipopolysaccharide induced chorioamnionitis in the fetal sheep
    Clare A Berry
    Division of Pulmonary Biology Neonatology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Reprod Sci 18:1092-102. 2011
    ..We conclude that IL-1 and LPS both can cause chorioamnionitis, but IL-1 is not an important mediator of LPS-induced chorioamnionitis in fetal sheep...
  8. ncbi Pulmonary and systemic expression of monocyte chemotactic proteins in preterm sheep fetuses exposed to lipopolysaccharide-induced chorioamnionitis
    Tushar A Shah
    Divisions of Neonatology and Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Pediatr Res 68:210-5. 2010
    ..LPS or IL-1 can induce robust expression of MCP-1 or MCP-2 in the fetal lung. LPS induction of MCP-1 is not IL-1 dependent in fetal sheep. MCP-1 and MCP-2 may be significant contributors to fetal inflammation...
  9. ncbi High and low body temperature during the initiation of ventilation for near-term lambs
    Molly K Ball
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Resuscitation 80:133-7. 2009
    ..Recent literature suggests hypothermia may protect against lung injury. We evaluated body temperature as a variable in lung inflammation due to oxygenation and mechanical ventilation following delivery of near-term lambs...
  10. ncbi Toll-like receptors and agonist responses in the developing fetal sheep lung
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Pediatr Res 63:388-93. 2008
    ..We conclude that TLR2 and TLR4 mRNAs increase through gestation and expression of TLR2 and TLR4 are induced by LPS in the fetal sheep lung...
  11. ncbi Pulmonary and systemic endotoxin tolerance in preterm fetal sheep exposed to chorioamnionitis
    Suhas G Kallapur
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    J Immunol 179:8491-9. 2007
    ..The findings have implications for preterm infants exposed to chorioamnionitis for both responses to lung injury and postnatal nosocomial infections...
  12. ncbi Chronic fetal exposure to Ureaplasma parvum suppresses innate immune responses in sheep
    Suhas G Kallapur
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA
    J Immunol 187:2688-95. 2011
    ..parvum. The findings increase our understanding of how chorioamnionitis-exposed preterm infants may respond to lung injury and postnatal nosocomial infections...
  13. ncbi Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Am J Respir Crit Care Med 176:575-81. 2007
    ..Premature infants are exposed to potentially injurious ventilation in the delivery room. Assessments of lung injury are confounded by effects of subsequent ventilatory support...
  14. ncbi An MRI system for imaging neonates in the NICU: initial feasibility study
    Jean A Tkach
    Imaging Research Center, Department of Radiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, MLC 5033, Cincinnati, OH 45229, USA
    Pediatr Radiol 42:1347-56. 2012
    ..Transporting premature infants from a neonatal intensive care unit (NICU) to a radiology department for MRI has medical risks and logistical challenges...
  15. ncbi Physiology of transition from intrauterine to extrauterine life
    Noah H Hillman
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, ML 7029, Cincinnati, OH 45229 3039, USA
    Clin Perinatol 39:769-83. 2012
    ..Abnormalities in adaptation are frequently found following preterm birth or cesarean delivery at term, and many of these infants need delivery room resuscitation to assist in this transition...