Genomes and Genes
DEBROSKI R HERBERT
Affiliation: Cincinnati Children's Hospital Medical Center
- Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infectionMarsha Wills-Karp
Division of Immunobiology and 2 Division of Asthma Research, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Exp Med 209:607-22. 2012..These experiments extend the biological functions of TFF2 from tissue repair to the initiation and maintenance of mucosal T(H)2 responses...
- Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasisDe Broski R Herbert
Research Service, Cincinnati Veterans Administration Medical Center, Cincinnati, OH 45220, USA
J Immunol 184:6438-46. 2010..Thus, macrophage-derived Arg I protects hosts against excessive tissue injury caused by worm eggs during acute schistosomiasis by suppressing IL-12/IL-23p40 production and maintaining the Treg/Th17 balance within the intestinal mucosa...