Devon L Graham

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Effects of developmental stress and lead (Pb) on corticosterone after chronic and acute stress, brain monoamines, and blood Pb levels in rats
    Devon L Graham
    Division of Neurology, Cincinnati Children s Research Foundation, Cincinnati, OH 45229 3039, USA
    Int J Dev Neurosci 29:45-55. 2011
  2. doi Distinct periods of developmental sensitivity to the effects of 3,4-(±)-methylenedioxymethamphetamine (MDMA) on behaviour and monoamines in rats
    Matthew R Skelton
    Division of Neurology, Cincinnati Children s Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Int J Neuropsychopharmacol 15:811-24. 2012
  3. pmc Comparison of (+)-methamphetamine, ±-methylenedioxymethamphetamine, (+)-amphetamine and ±-fenfluramine in rats on egocentric learning in the Cincinnati water maze
    Charles V Vorhees
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Synapse 65:368-78. 2011
  4. doi Neonatal +-methamphetamine exposure in rats alters adult locomotor responses to dopamine D1 and D2 agonists and to a glutamate NMDA receptor antagonist, but not to serotonin agonists
    Devon L Graham
    Division of Neurology, Cincinnati Children s Research Foundation, Cincinnati, OH 45229 3039, USA
    Int J Neuropsychopharmacol 16:377-91. 2013
  5. doi Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA
    Tori L Schaefer
    Division of Child Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Int J Neuropsychopharmacol 16:1383-94. 2013
  6. pmc Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC
    Charles V Vorhees
    Division of Neurology, Cincinnati Children s Research Foundation, Cincinnati, Ohio 45229, USA
    Synapse 66:725-37. 2012
  7. pmc Effect of a neurotoxic dose regimen of (+)-methamphetamine on behavior, plasma corticosterone, and brain monoamines in adult C57BL/6 mice
    Curtis E Grace
    Division of Neurology, Dept of Pediatrics, Cincinnati Children s Research Foundation, Cincinnati, Ohio, United States
    Neurotoxicol Teratol 32:346-55. 2010
  8. pmc Effects of inhibiting neonatal methamphetamine-induced corticosterone release in rats by adrenal autotransplantation on later learning, memory, and plasma corticosterone levels
    Curtis E Grace
    Division of Neurology, Dept of Pediatrics, Cincinnati Children s Research Foundation, Cincinnati, OH 45229 3039, United States
    Int J Dev Neurosci 28:331-42. 2010
  9. pmc Neurobehavioral phenotype of C57BL/6J mice prenatally and neonatally exposed to cigarette smoke
    Robyn M Amos-Kroohs
    Department of Pediatrics, Division of Child Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, United States
    Neurotoxicol Teratol 35:34-45. 2013
  10. pmc Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug
    Charles V Vorhees
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Behav Brain Funct 7:41. 2011

Collaborators

Detail Information

Publications14

  1. pmc Effects of developmental stress and lead (Pb) on corticosterone after chronic and acute stress, brain monoamines, and blood Pb levels in rats
    Devon L Graham
    Division of Neurology, Cincinnati Children s Research Foundation, Cincinnati, OH 45229 3039, USA
    Int J Dev Neurosci 29:45-55. 2011
    ..The model introduced here may be useful for investigating the interaction of Pb and chronic developmental stress...
  2. doi Distinct periods of developmental sensitivity to the effects of 3,4-(±)-methylenedioxymethamphetamine (MDMA) on behaviour and monoamines in rats
    Matthew R Skelton
    Division of Neurology, Cincinnati Children s Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Int J Neuropsychopharmacol 15:811-24. 2012
    ..Other effects, such as those upon MK-801-stimulated locomotion showed greatest effects after PD 1-10 MDMA exposure. Hence, each effect has a different window of developmental susceptibility...
  3. pmc Comparison of (+)-methamphetamine, ±-methylenedioxymethamphetamine, (+)-amphetamine and ±-fenfluramine in rats on egocentric learning in the Cincinnati water maze
    Charles V Vorhees
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Synapse 65:368-78. 2011
    ..Given that FEN selectively and MDMA preferentially affect serotonin whereas AMPH selectively and MA preferentially affect DA, the data suggest that egocentric learning may be predominantly dopaminergically mediated...
  4. doi Neonatal +-methamphetamine exposure in rats alters adult locomotor responses to dopamine D1 and D2 agonists and to a glutamate NMDA receptor antagonist, but not to serotonin agonists
    Devon L Graham
    Division of Neurology, Cincinnati Children s Research Foundation, Cincinnati, OH 45229 3039, USA
    Int J Neuropsychopharmacol 16:377-91. 2013
    ....
  5. doi Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA
    Tori L Schaefer
    Division of Child Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Int J Neuropsychopharmacol 16:1383-94. 2013
    ..These data indicate the need for further research on the long-term safety of antidepressants during pregnancy...
  6. pmc Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC
    Charles V Vorhees
    Division of Neurology, Cincinnati Children s Research Foundation, Cincinnati, Ohio 45229, USA
    Synapse 66:725-37. 2012
    ....
  7. pmc Effect of a neurotoxic dose regimen of (+)-methamphetamine on behavior, plasma corticosterone, and brain monoamines in adult C57BL/6 mice
    Curtis E Grace
    Division of Neurology, Dept of Pediatrics, Cincinnati Children s Research Foundation, Cincinnati, Ohio, United States
    Neurotoxicol Teratol 32:346-55. 2010
    ..In rats, neurotoxic doses of methamphetamine (MA) induce astrogliosis, long lasting monoamine reductions, reuptake transporter down-regulation, and learning impairments...
  8. pmc Effects of inhibiting neonatal methamphetamine-induced corticosterone release in rats by adrenal autotransplantation on later learning, memory, and plasma corticosterone levels
    Curtis E Grace
    Division of Neurology, Dept of Pediatrics, Cincinnati Children s Research Foundation, Cincinnati, OH 45229 3039, United States
    Int J Dev Neurosci 28:331-42. 2010
    ..We previously developed a method to attenuate MA-induced corticosterone release using adrenal autotransplantation (ADXA) in neonatal rats. This exposure period corresponds to the second-half of human pregnancy...
  9. pmc Neurobehavioral phenotype of C57BL/6J mice prenatally and neonatally exposed to cigarette smoke
    Robyn M Amos-Kroohs
    Department of Pediatrics, Division of Child Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, United States
    Neurotoxicol Teratol 35:34-45. 2013
    ..The findings add support to mounting evidence that developmental cigarette smoke exposure has long-term adverse effects on brain function...
  10. pmc Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug
    Charles V Vorhees
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Behav Brain Funct 7:41. 2011
    ..Whether selective serotonin reuptake inhibitors (SSRIs) exposure during adolescent brain development causes lasting effects remains unresolved...
  11. doi Dorsal striatal dopamine depletion impairs both allocentric and egocentric navigation in rats
    Amanda A Braun
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation, Cincinnati, OH 45229, USA
    Neurobiol Learn Mem 97:402-8. 2012
    ..In addition, 6-OHDA increased DA turnover and decreased norepinephrine (NE) levels. 6-OHDA injections did not alter monoamine levels in the prefrontal cortex. The data support that neostriatal DA modulates both types of navigation...
  12. pmc Creatine transporter (CrT; Slc6a8) knockout mice as a model of human CrT deficiency
    Matthew R Skelton
    Division of Neurology, Cincinnati Children s Research Foundation, and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e16187. 2011
    ..Ubiquitous CrT knockout mice have learning and memory deficits resembling human CrT deficiency and this model should be useful in understanding this disorder...
  13. pmc Effects of (+)-methamphetamine on path integration and spatial learning, but not locomotor activity or acoustic startle, align with the stress hyporesponsive period in rats
    Charles V Vorhees
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Research Foundation and University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Int J Dev Neurosci 27:289-98. 2009
    ..Cognitive deficits from neonatal MA treatment are associated with the SHRP and may be the product of hypothalamic-pituitary-adrenal (HPA) axis dysregulation during critical periods of brain development...
  14. pmc Glucose and corticosterone changes in developing and adult rats following exposure to (+/-)-3,4-methylendioxymethamphetamine or 5-methoxydiisopropyltryptamine
    Devon L Graham
    Division of Neurology, Cincinnati Children s Research Foundation, and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
    Neurotoxicol Teratol 32:152-7. 2010
    ..The data indicate that an acute exposure to these drugs alters CORT and glucose levels, raising the possibility that these changes may have effects on behavioral and cognitive function, as we and others have previously demonstrated...