Stuart L Goldstein

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi AKI transition of care: a potential opportunity to detect and prevent CKD
    Stuart L Goldstein
    Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Clin J Am Soc Nephrol 8:476-83. 2013
  2. ncbi Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial
    Stuart L Goldstein
    University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Am J Kidney Dis 61:588-97. 2013
  3. ncbi Acute kidney injury in children and its potential consequences in adulthood
    Stuart L Goldstein
    Center for Acute Care Nephrology, Division of Nephrology and Hypertension, The Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45206, USA
    Blood Purif 33:131-7. 2012
  4. ncbi Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray
    Rajit K Basu
    Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45223, USA
    Crit Care 15:R273. 2011
  5. ncbi Therapeutic apheresis in children: special considerations
    Stuart L Goldstein
    Department of Pediatrics, University of Cincinnati College of Medicine and the Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45206, USA
    Semin Dial 25:165-70. 2012
  6. ncbi Acute kidney injury biomarkers: renal angina and the need for a renal troponin I
    Stuart L Goldstein
    Center for Acute Care Nephrology, Division of Nephrology and Hypertension, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    BMC Med 9:135. 2011
  7. ncbi Advances in pediatric renal replacement therapy for acute kidney injury
    Stuart L Goldstein
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Semin Dial 24:187-91. 2011
  8. ncbi Continuous renal replacement therapy: mechanism of clearance, fluid removal, indications and outcomes
    Stuart L Goldstein
    University of Cincinnati College of Medicine, The Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45206, USA
    Curr Opin Pediatr 23:181-5. 2011
  9. ncbi A novel use for novel acute kidney injury biomarkers: fenoldopam's effect on neutrophil gelatinase-associated lipocalin and cystatin C
    Stuart L Goldstein
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 7022, Cincinnati, OH 45206, USA
    Crit Care 15:177. 2011
  10. ncbi Urinary kidney injury biomarkers and urine creatinine normalization: a false premise or not?
    Stuart L Goldstein
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Kidney Int 78:433-5. 2010

Detail Information

Publications45

  1. ncbi AKI transition of care: a potential opportunity to detect and prevent CKD
    Stuart L Goldstein
    Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Clin J Am Soc Nephrol 8:476-83. 2013
    ..Therefore, prospective study of transitions of care after episodes of AKI is needed to identify which patients are at risk for CKD development and to optimally target therapeutic interventions...
  2. ncbi Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial
    Stuart L Goldstein
    University of Cincinnati College of Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Am J Kidney Dis 61:588-97. 2013
    ..Iron repletion with intravenous (IV) iron formulations has been studied in children; maintenance IV iron regimens have not been reported extensively...
  3. ncbi Acute kidney injury in children and its potential consequences in adulthood
    Stuart L Goldstein
    Center for Acute Care Nephrology, Division of Nephrology and Hypertension, The Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45206, USA
    Blood Purif 33:131-7. 2012
    ..The purpose of this article is to review the changing epidemiology of pediatric AKI and its potential effect on the development of CKD in children...
  4. ncbi Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray
    Rajit K Basu
    Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45223, USA
    Crit Care 15:R273. 2011
    ..The objective of our study was to determine whether microarray data from children with septic shock could be used to derive a panel of candidate biomarkers for predicting SSAKI...
  5. ncbi Therapeutic apheresis in children: special considerations
    Stuart L Goldstein
    Department of Pediatrics, University of Cincinnati College of Medicine and the Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45206, USA
    Semin Dial 25:165-70. 2012
    ....
  6. ncbi Acute kidney injury biomarkers: renal angina and the need for a renal troponin I
    Stuart L Goldstein
    Center for Acute Care Nephrology, Division of Nephrology and Hypertension, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    BMC Med 9:135. 2011
    ..The optimal and appropriate utilization of AKI biomarkers will only be realized by understanding their characteristics and placing reasonable expectations on their performance in the clinical arena...
  7. ncbi Advances in pediatric renal replacement therapy for acute kidney injury
    Stuart L Goldstein
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Semin Dial 24:187-91. 2011
    ..We will focus on the application of different RRT modalities and related outcome of children with AKI who receive RRT...
  8. ncbi Continuous renal replacement therapy: mechanism of clearance, fluid removal, indications and outcomes
    Stuart L Goldstein
    University of Cincinnati College of Medicine, The Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45206, USA
    Curr Opin Pediatr 23:181-5. 2011
    ..However, confusion still exists with respect to CRRT terminology and the optimal use of this modality across the entire pediatric disease and age spectrum...
  9. ncbi A novel use for novel acute kidney injury biomarkers: fenoldopam's effect on neutrophil gelatinase-associated lipocalin and cystatin C
    Stuart L Goldstein
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 7022, Cincinnati, OH 45206, USA
    Crit Care 15:177. 2011
    ..Given the high sensitivity of NGAL for AKI post cardiopulmonary bypass, this study provides a model to use novel AKI biomarkers in a novel manner...
  10. ncbi Urinary kidney injury biomarkers and urine creatinine normalization: a false premise or not?
    Stuart L Goldstein
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Kidney Int 78:433-5. 2010
    ..Waikar et al. challenge the assumption that normalization to creatinine clearance in a chronic disease state can be extrapolated to an acute state, in which creatinine clearance is, by definition, changing acutely...
  11. ncbi Acute kidney injury in children: prevention, treatment and rehabilitation
    Stuart L Goldstein
    University of Cincinnati College of Medicine, Director, Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Contrib Nephrol 174:163-72. 2011
    ..The scope of this article is to review the advancements in the study of pediatric AKI over the past decade and offer a compelling and bright view of what is on the horizon for the prevention, treatment and rehabilitation of AKI in kids...
  12. ncbi Acute kidney injury in childhood: should we be worried about progression to CKD?
    Stuart L Goldstein
    Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 7022, Cincinnati, OH 54229 3039, USA
    Pediatr Nephrol 26:509-22. 2011
    ....
  13. ncbi Continuous renal replacement therapy (CRRT) after stem cell transplantation. A report from the prospective pediatric CRRT Registry Group
    Francisco X Flores
    Department of Pediatrics, Division of Nephrology, University of South Florida College of Medicine, All Children s Hospital, St Petersburg, FL, USA
    Pediatr Nephrol 23:625-30. 2008
    ..7 +/- 2.94 vs 25.76 +/- 2.03 mmH(2)O, P < 0.05). Development of high mean airway pressure in non-survivors is likely related to non-fluid injury, as it was not prevented by early and aggressive fluid management by CRRT therapy...
  14. ncbi Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry
    Scott M Sutherland
    Department of Pediatrics, Stanford University School of Medicine and Lucile Packard Children s Hospital, Palo Alto, CA, USA
    Am J Kidney Dis 55:316-25. 2010
    ..Continuous renal replacement therapy (CRRT) has emerged as a favored modality in the management of such children. This study investigated the association between fluid overload and mortality in children receiving CRRT...
  15. ncbi Fluid overload is associated with impaired oxygenation and morbidity in critically ill children
    Ayse A Arikan
    Section of Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Pediatr Crit Care Med 13:253-8. 2012
    ..Since increasing disease severity often requires more fluid for resuscitation, it is unclear whether fluid overload is a causative factor in morbidity or is simply an indicator of disease severity...
  16. ncbi Elevated FGF 23 and phosphorus are associated with coronary calcification in hemodialysis patients
    Poyyapakkam R Srivaths
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX, 77030, USA
    Pediatr Nephrol 26:945-51. 2011
    ..This study confirms the occurrence of CC in pediatric HD patients and is the first to show a significant association between CC and elevated serum FGF 23 in children...
  17. ncbi Malnutrition-inflammation-coronary calcification in pediatric patients receiving chronic hemodialysis
    Poyyapakkam R Srivaths
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, Texas, USA
    Hemodial Int 14:263-9. 2010
    ..Coronary calcification was prevalent in older children receiving maintenance hemodialysis with a longer dialysis vintage. Worse renal osteodystrophy control and malnutrition (low cholesterol) may contribute to CC development...
  18. ncbi Nonrenal indications for continuous renal replacement therapy: A report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group
    Geoffrey M Fleming
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA
    Pediatr Crit Care Med 13:e299-304. 2012
    ..However, it also has a role in the management of patients with nonrenal indications such as clearance of drugs and intermediates of disordered cellular metabolism...
  19. ncbi Frequent hemodialysis with NxStage system in pediatric patients receiving maintenance hemodialysis
    Stuart L Goldstein
    Department of Pediatrics, Renal, Baylor College of Medicine, Houston, TX, USA
    Pediatr Nephrol 23:129-35. 2008
    ..Variable changes in proinflammatory cytokine levels were observed. We suggest that frequent HD with the NxStage system be considered for children who would benefit from home-based maintenance dialysis...
  20. ncbi Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass
    Catherine D Krawczeski
    The Heart Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    J Am Coll Cardiol 58:2301-9. 2011
    ....
  21. ncbi Demographic characteristics of pediatric continuous renal replacement therapy: a report of the prospective pediatric continuous renal replacement therapy registry
    Jordan M Symons
    Department of Pediatrics, University of Washington School of Medicine and Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
    Clin J Am Soc Nephrol 2:732-8. 2007
    ..This article reports demographic characteristics and intensive care unit survival for 344 patients from the Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) Registry, a voluntary multicenter observational network...
  22. ncbi Renal angina
    Stuart L Goldstein
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, Texas, USA
    Clin J Am Soc Nephrol 5:943-9. 2010
    ..The purpose of this article is to review both adult and pediatric AKI literature to devise a definition for a renal anginal syndrome equivalent...
  23. ncbi Acute kidney injury in non-critically ill children treated with aminoglycoside antibiotics in a tertiary healthcare centre: a retrospective cohort study
    Michael Zappitelli
    Division of Nephrology, McGill University Health Centre, Montreal, Canada
    Nephrol Dial Transplant 26:144-50. 2011
    ..We determined the incidence, severity and risk factors of AG-associated AKI and assessed for associations with longer hospitalization and higher costs...
  24. ncbi Renal angina: an emerging paradigm to identify children at risk for acute kidney injury
    Rajit K Basu
    Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Pediatr Nephrol 27:1067-78. 2012
    ..Fulfillment of renal angina criteria will improve the efficiency of AKI prediction by biomarkers, in turn expediting early therapy and assisting in creation of AKI-predictive scoring systems...
  25. ncbi Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants
    David J Askenazi
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Pediatr Res 70:302-6. 2011
    ..We conclude that urine values of candidate AKI biomarkers are higher in the most premature infants. These findings should be considered when designing and analyzing biomarker studies in newborn with AKI...
  26. ncbi Continuous renal replacement therapy amino acid, trace metal and folate clearance in critically ill children
    Michael Zappitelli
    Renal Section, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Intensive Care Med 35:698-706. 2009
    ..We hypothesized continuous veno-venous hemodialysis (CVVHD) amino acid, trace metals and folate clearance impacts nutrient balance...
  27. ncbi Biomarkers of acute kidney injury in pediatric cardiac patients
    David M Kwiatkowski
    Cincinnati Children s Hospital Medical Center, OH, USA
    Biomark Med 6:273-82. 2012
    ..Further clinical validation and broader commercial availability of these novel biomarkers will probably revolutionize the care of pediatric cardiac patients with renal injury...
  28. ncbi Pro- and anti-inflammatory cytokines in chronic pediatric dialysis patients: effect of aspirin
    Stuart L Goldstein
    Department of Pediatrics, Renal Section, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA
    Clin J Am Soc Nephrol 1:979-86. 2006
    ..It is concluded that proinflammatory cytokines are elevated in pediatric HD and PD patients without counterbalance from anti-inflammatory cytokines, and aspirin therapy attenuates inflammation...
  29. ncbi Vascular access complications in long-term pediatric hemodialysis patients
    Joshua J Zaritsky
    Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Pediatr Nephrol 23:2061-5. 2008
    ..These findings further emphasize the need to use AVG/AVFs as primary HD access for pediatric patients expected to receive a long course of maintenance HD...
  30. ncbi Nutrition aspects in children receiving maintenance hemodialysis: impact on outcome
    Poyyapakkam R Srivaths
    Department of Pediatrics, Baylor College of Medicine and Renal Services, Texas Children s Hospital, Houston, TX 77030, USA
    Pediatr Nephrol 24:951-7. 2009
    ..This article is a state-of-the-art review of malnutrition in children receiving maintenance hemodialysis, with special focus on outcome, nPCR and IDPN...
  31. ncbi Progression from acute kidney injury to chronic kidney disease: a pediatric perspective
    Stuart L Goldstein
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX, USA
    Adv Chronic Kidney Dis 15:278-83. 2008
    ....
  32. ncbi Pediatric patients with multi-organ dysfunction syndrome receiving continuous renal replacement therapy
    Stuart L Goldstein
    Department of Pediatrics, Renal Section, Baylor College of Medicine and Texas Children s Hospital, Houston, Texas 77030, USA
    Kidney Int 67:653-8. 2005
    ....
  33. ncbi Urinary nitrate might be an early biomarker for pediatric acute kidney injury in the emergency department
    Asad I Mian
    Department of Pediatrics, Texas Children s Hospital, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 70:203-7. 2011
    ..Thus, low urinary nitrate is associated with AKI in the pediatric ED even when SCr is normal. Predictive potential of this putative urinary biomarker for AKI needs further evaluation in sicker patients...
  34. ncbi Quality of life for children with chronic kidney disease
    Stuart L Goldstein
    Department of Pediatrics, Baylor of Medicine and Renal Dialysis Unit, Texas Children s Hospital, Houston, TX 77030, USA
    Semin Nephrol 26:114-7. 2006
    ..We review the range of issues that impact pediatric CKD patients' health-related quality of life (HRQOL), the history of pediatric CKD patients' HRQOL investigation, and the instruments currently available to assess HRQOL...
  35. ncbi Anemia and growth status in pediatric patients receiving maintenance dialysis after a failed renal transplant course: an NAPRTCS report
    Stuart L Goldstein
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Pediatr Transplant 11:201-4. 2007
    ....
  36. ncbi Overview of pediatric renal replacement therapy in acute kidney injury
    Stuart L Goldstein
    Department of Pediatrics, Baylor College of Medicine, Renal Dialysis Unit and Pheresis Service, Texas Children s Hospital, 6621 Fannin Street, Houston, TX 77030, USA
    Semin Dial 22:180-4. 2009
    ....
  37. ncbi Physical fitness in children with end-stage renal disease
    Stuart L Goldstein
    Department of Pediatrics, Baylor College of Medicine, Renal Dialysis Unit and Pheresis Service, Texas Children s Hospital, Houston, TX 77030, USA
    Adv Chronic Kidney Dis 16:430-6. 2009
    ..This article reviews studies that detail the physical components of HRQOL as well as other studies that have started to document the exercise capacity of children with ESRD...
  38. ncbi Topical mupirocin/sodium hypochlorite reduces peritonitis and exit-site infection rates in children
    Annabelle N Chua
    Department of Pediatrics, Renal Division, Houston, TX 77030, USA
    Clin J Am Soc Nephrol 4:1939-43. 2009
    ..The effect of topical mupirocin (Mup) and sodium hypochlorite (NaOCl) solution was evaluated as part of routine daily exit site care on peritonitis and ESI/TI rates, causative microorganisms, and catheter survival rates...
  39. ncbi Cardorenal syndrome: an emerging problem in pediatric critical care
    John Lynn Jefferies
    The Heart Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 2003, Cincinnati, OH, 45243, USA
    Pediatr Nephrol 28:855-62. 2013
    ..Herein, we briefly report on the adult literature and summarize the current pediatric experience...
  40. ncbi Two-point normalized protein catabolic rate overestimates nPCR in pediatric hemodialysis patients
    Poyyapakkam R Srivaths
    Renal Section, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, TX 77030, USA
    Pediatr Nephrol 28:797-801. 2013
    ..This study aimed to compare nPCR calculated with a two-point vs. a three-point nPCR model in pediatric HD patients...
  41. ncbi Health-related quality of life functioning over a 2-year period in children with end-stage renal disease
    Shari K Neul
    Renal Section, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, One Baylor Plaza Houston, Houston, TX 77030, USA
    Pediatr Nephrol 28:285-93. 2013
    ..Optimal care of the pediatric chronic kidney disease/end stage renal disease (CKD/ESRD) patient must now incorporate health-related quality of life (HRQOL) assessment and management...
  42. ncbi Erythrocytapheresis in children with sickle cell disease and acute chest syndrome
    M Paulina Velasquez
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    Pediatr Blood Cancer 53:1060-3. 2009
    ..Red cell exchange (RCE) is part of the management of acute chest syndrome (ACS) in patients with sickle cell disease. The study describes the indications and outcome of the procedure...
  43. ncbi Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome?
    Jack F Price
    Department of Pediatrics, Baylor College of Medicine, The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children s Hospital, Houston, TX, USA
    Pediatr Crit Care Med 9:279-84. 2008
    ..The purpose of this study was to determine the incidence of renal insufficiency in children hospitalized with acute decompensated heart failure and whether worsening renal function is associated with adverse cardiovascular outcome...
  44. ncbi A standard, noninvasive monitoring of hematocrit algorithm improves blood pressure control in pediatric hemodialysis patients
    Hiren P Patel
    Department of Pediatrics, Section of Nephrology, Columbus Children s Hospital, Ohio State University College of Medicine, Columbus, Ohio 43205, USA
    Clin J Am Soc Nephrol 2:252-7. 2007
    ..Wider use of NIVM-guided ultrafiltration may decrease cardiovascular morbidity in pediatric hemodialysis patients...
  45. ncbi Comparison of 1-84 and intact parathyroid hormone assay in pediatric dialysis patients
    Rita D Sheth
    Department of Pediatrics, Baylor College of Medicine, and Texas Children s Hospital, 6621 Fannin Street MC 3 2482, Houston, TX 77030, USA
    Pediatr Nephrol 20:977-81. 2005
    ..Thus, our findings suggest that ROD management based on prior associations between iPTH levels and bone biopsy findings should not be extrapolated using the newer 1-84 PTH assay...