D L Gilbert

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi request reprint Factors affecting the yield of pediatric EEGs in clinical practice
    Donald L Gilbert
    Department of Neurology, Children s Hospital Medical Center, University of Cincinnati, Ohio 45229 3039, USA
    Clin Pediatr (Phila) 41:25-32. 2002
  2. ncbi request reprint Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndrome
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Mov Disord 19:416-25. 2004
  3. ncbi request reprint Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortex
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH 45229, USA
    Neuropsychopharmacology 31:442-9. 2006
  4. ncbi request reprint Assessment of scientific and ethical issues in two randomized clinical trial designs for patients with Tourette's syndrome: a model for studies of multiple neuropsychiatric diagnoses
    Donald L Gilbert
    Cincinnati Children s Hospital Medical Center, ML 2015, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    J Neuropsychiatry Clin Neurosci 17:324-32. 2005
  5. ncbi request reprint Does sleep or sleep deprivation increase epileptiform discharges in pediatric electroencephalograms?
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, ML 2015, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Pediatrics 114:658-62. 2004
  6. ncbi request reprint Should transcranial magnetic stimulation research in children be considered minimal risk?
    Donald L Gilbert
    Division of Pediatric Neurology, Movement Disorders Clinics, Cincinnati Children s Hospital Medical Center, ML 2015, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Clin Neurophysiol 115:1730-9. 2004
  7. ncbi request reprint Altered mesolimbocortical and thalamic dopamine in Tourette syndrome
    D L Gilbert
    Movement Disorder Clinic, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Neurology 67:1695-7. 2006
  8. pmc Atomoxetine treatment of ADHD in Tourette syndrome: reduction in motor cortex inhibition correlates with clinical improvement
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, and The University of Cincinnati, Department of Neurology, School of Medicine, OH 45229 3039, USA
    Clin Neurophysiol 118:1835-41. 2007
  9. ncbi request reprint Tic reduction with risperidone versus pimozide in a randomized, double-blind, crossover trial
    Donald L Gilbert
    Department of Neurology, Cincinnati Children s Hospital Medical Center, Division of Developmental and Behavioral Sciences Children s Mercy Hospital, Kansas City, KS, USA
    J Am Acad Child Adolesc Psychiatry 43:206-14. 2004
  10. ncbi request reprint Dopamine transporter genotype influences the physiological response to medication in ADHD
    Donald L Gilbert
    Division of Neurology Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Brain 129:2038-46. 2006

Detail Information

Publications44

  1. ncbi request reprint Factors affecting the yield of pediatric EEGs in clinical practice
    Donald L Gilbert
    Department of Neurology, Children s Hospital Medical Center, University of Cincinnati, Ohio 45229 3039, USA
    Clin Pediatr (Phila) 41:25-32. 2002
    ..001). In practice most electroencephalograms ordered for seizure are actually for non-seizure. In routine pediatric practice, electroencephalography has a low yield and appears to be over-used...
  2. ncbi request reprint Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndrome
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Mov Disord 19:416-25. 2004
    ..53; P = 0.003) than with tic severity (r = 0.42; P = 0.02), suggesting that in TS, the association between SICI and ADHD symptoms may be more consistent or direct than the association between SICI and tics...
  3. ncbi request reprint Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortex
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH 45229, USA
    Neuropsychopharmacology 31:442-9. 2006
    ..Cortical inhibition, shown previously to be abnormal in ADHD, may play a key role producing behavioral pathology...
  4. ncbi request reprint Assessment of scientific and ethical issues in two randomized clinical trial designs for patients with Tourette's syndrome: a model for studies of multiple neuropsychiatric diagnoses
    Donald L Gilbert
    Cincinnati Children s Hospital Medical Center, ML 2015, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    J Neuropsychiatry Clin Neurosci 17:324-32. 2005
    ....
  5. ncbi request reprint Does sleep or sleep deprivation increase epileptiform discharges in pediatric electroencephalograms?
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, ML 2015, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Pediatrics 114:658-62. 2004
    ..The objective of this study was to compare the effects of sleep, standard sleep deprivation, partial sleep deprivation, and no sleep deprivation on the odds of an epileptiform abnormality in outpatient pediatric EEGs...
  6. ncbi request reprint Should transcranial magnetic stimulation research in children be considered minimal risk?
    Donald L Gilbert
    Division of Pediatric Neurology, Movement Disorders Clinics, Cincinnati Children s Hospital Medical Center, ML 2015, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Clin Neurophysiol 115:1730-9. 2004
    ..The purpose of this study is to provide concise information for investigators and IRBs about the safety of single and paired pulse TMS research in children...
  7. ncbi request reprint Altered mesolimbocortical and thalamic dopamine in Tourette syndrome
    D L Gilbert
    Movement Disorder Clinic, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Neurology 67:1695-7. 2006
    ..Altered dopaminergic function in mesolimbocortical systems and thalamus may contribute to increased motivational salience of tics...
  8. pmc Atomoxetine treatment of ADHD in Tourette syndrome: reduction in motor cortex inhibition correlates with clinical improvement
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, and The University of Cincinnati, Department of Neurology, School of Medicine, OH 45229 3039, USA
    Clin Neurophysiol 118:1835-41. 2007
    ..We sought to determine in children with Tourette Syndrome (TS) whether clinical responses correlate with changes in short interval cortical inhibition (SICI)...
  9. ncbi request reprint Tic reduction with risperidone versus pimozide in a randomized, double-blind, crossover trial
    Donald L Gilbert
    Department of Neurology, Cincinnati Children s Hospital Medical Center, Division of Developmental and Behavioral Sciences Children s Mercy Hospital, Kansas City, KS, USA
    J Am Acad Child Adolesc Psychiatry 43:206-14. 2004
    ..To compare the tic suppression, electrocardiogram (ECG) changes, weight gain, and side effect profiles of pimozide versus risperidone in children and adolescents with tic disorders...
  10. ncbi request reprint Dopamine transporter genotype influences the physiological response to medication in ADHD
    Donald L Gilbert
    Division of Neurology Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Brain 129:2038-46. 2006
    ..In conclusion, MPH and ATX have similar effects on SICI in children with ADHD. A genetic variation in DAT1, previously linked to ADHD risk and MPH behavioural responses, influences the neurophysiological effects of both MPH and ATX...
  11. doi request reprint A novel hereditary spastic paraplegia with dystonia linked to chromosome 2q24-2q31
    Donald L Gilbert
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, Ohio 45229 3039, USA
    Mov Disord 24:364-70. 2009
    ..0. On the basis of clinical presentation and linkage results, we conclude that this disease is a novel neurological disorder. Identifying the causative gene may elucidate an important pathway for pyramidal and extrapyramidal disorders...
  12. ncbi request reprint Transcranial magnetic stimulation-evoked cortical inhibition: a consistent marker of attention-deficit/hyperactivity disorder scores in tourette syndrome
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center and University of Cincinnati, OH 45229 3039, USA
    Biol Psychiatry 57:1597-600. 2005
    ..We sought to validate this observation...
  13. ncbi request reprint Tourette's syndrome improvement with pergolide in a randomized, double-blind, crossover trial
    D L Gilbert
    Children s Hospital Medical Center, Department of Neurology, University of Cincinnati, OH 45229 3039, USA
    Neurology 54:1310-5. 2000
    ..To determine whether pergolide, a mixed D1-D2-D3 dopamine agonist, is efficacious and safe in the treatment of children with Tourette's syndrome...
  14. doi request reprint Body mass index changes and chronic neuroleptic drug treatment for Tourette syndrome
    Roosje S Degrauw
    Tourette Syndrome and Movement Disorders Clinics, Division of Neurology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati School of Medicine, Cincinnati, Ohio, USA
    Pediatr Neurol 41:183-6. 2009
    ..6) = 6.34, P = 0.0007), related to first-year changes only. In children and adolescents with Tourette syndrome treated for longer than 1 year with neuroleptics, weight gain is not necessarily excessive...
  15. pmc Motor cortex inhibition: a marker of ADHD behavior and motor development in children
    D L Gilbert
    Transcranial Magnetic Stimulation Laboratory, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Neurology 76:615-21. 2011
    ....
  16. ncbi request reprint Tic reduction with pergolide in a randomized controlled trial in children
    D L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Neurology 60:606-11. 2003
    ..To determine whether pergolide, a mixed D1/D2/D3 dopamine agonist, is efficacious and safe in the treatment of children with chronic tic disorders and Tourette syndrome...
  17. doi request reprint Assessing quality and normalization of microarrays: case studies using neurological genomic data
    A D Hershey
    Department of Pediatrics, Divisions of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Acta Neurol Scand 118:29-41. 2008
    ..The analysis of these data is complex due to the large amount of data generated. Many tools have been developed to assist with this, but standard methods of analysis of these tools have not been established...
  18. doi request reprint Tic suppression: the medical model
    Steve W Wu
    Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Child Adolesc Psychopharmacol 20:263-76. 2010
    ..It concludes with some context for understanding this literature, relevant to treatment decisions and future treatment research in TD...
  19. doi request reprint The prevalence of neuropsychiatric disorders in Sydenham's chorea
    Keith R Ridel
    Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Pediatr Neurol 42:243-8. 2010
    ..During and after the diagnosis of Sydenham's chorea, clinicians should be vigilant for signs and symptoms of anxiety, depression, and attention deficit hyperactivity disorder...
  20. doi request reprint Acute and chronic chorea in childhood
    Donald L Gilbert
    Movement Disorders Clinics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Semin Pediatr Neurol 16:71-6. 2009
    ..We review the management of acute/subacute and chronic choreas, with special emphasis on Sydenham chorea and benign hereditary chorea...
  21. ncbi request reprint Clinical and positron emission tomography findings of chorea associated with primary antiphospholipid antibody syndrome
    Steve W Wu
    Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Mov Disord 22:1813-5. 2007
    ..His symptoms resolved on prednisone; however, his antiphospholipid antibody profile remained markedly abnormal despite being symptom-free for 26 months...
  22. doi request reprint Drug-induced movement disorders in children
    Donald L Gilbert
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Ann N Y Acad Sci 1142:72-84. 2008
    ..Many publications are small case series. This report attempts to provide useful information, with appropriate caution and discussion of the limitations of what we know...
  23. ncbi request reprint Efficacy and mortality in treatment of refractory generalized convulsive status epilepticus in children: a meta-analysis
    D L Gilbert
    Department of Neurology, Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Child Neurol 14:602-9. 1999
    ....
  24. ncbi request reprint Motor cortex inhibitory function in Tourette syndrome, attention deficit disorder, and obsessive compulsive disorder: studies using transcranial magnetic stimulation
    Donald L Gilbert
    Department of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Adv Neurol 99:107-14. 2006
  25. ncbi request reprint Dyskinesias associated with atomoxetine in combination with other psychoactive drugs
    G Randall Bond
    Drug and Poison Information Center, and Division of Emergency Medicine, Department of Pediatrics, Cincinnati Children s Hospital Medical Center and the University of Cincinnati, Cincinnati, Ohio USA
    Clin Toxicol (Phila) 45:182-5. 2007
    ..Serotonin syndrome is a possibility in the second case, but not the first. Clinicians should be aware of emergent dyskinesias when combining atomoxetine with dopaminergic, noradrenergic, or serotonergic medications...
  26. ncbi request reprint Glycine decarboxylase mutations: a distinctive phenotype of nonketotic hyperglycinemia in adults
    A Dinopoulos
    Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Neurology 64:1255-7. 2005
    ..Both mutations had a 6 to 8% of normal GLDC activities when expressed in COS7 cells...
  27. ncbi request reprint Complications and costs of treatment of refractory generalized convulsive status epilepticus in children
    D L Gilbert
    Department of Neurology, Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Child Neurol 14:597-601. 1999
    ..Benzodiazepines appear to have higher drug costs but lower complications and overall costs than barbiturates...
  28. ncbi request reprint A subgroup of Tourette's patients overexpress specific natural killer cell genes in blood: a preliminary report
    Lisa Lit
    Genetics Graduate Group, Department of Neurology, M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
    Am J Med Genet B Neuropsychiatr Genet 144:958-63. 2007
    ....
  29. ncbi request reprint Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study
    Y Tang
    Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
    Acta Neurol Scand 109:159-68. 2004
    ..The purpose of this pilot study is to examine the blood genomic expression pattern associated with VPA therapy in general and secondly VPA efficacy in children with epilepsy...
  30. ncbi request reprint Blood gene expression profiling of neurologic diseases: a pilot microarray study
    Yang Tang
    Department of Neurology and Neuroscience Program, University of Cincinnati, OH, USA
    Arch Neurol 62:210-5. 2005
    ..Tissue gene expression profiling with arrays measures the transcription of thousands of genes. However, this approach cannot be readily used to guide clinical neurologic practice...
  31. ncbi request reprint Meta-analysis of EEG test performance shows wide variation among studies
    Donald L Gilbert
    Division of Neurology, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Neurology 60:564-70. 2003
    ..EEG results are used for counseling patients with seizures about prognosis and deciding on medications. Published sensitivities of interictal EEG vary widely...
  32. doi request reprint Cerebellar ataxia in youths at risk for bipolar disorder
    Lisa L Giles
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 10:733-7. 2008
    ..The present study examined cerebellar function in youths who were at familial risk for BD by comparing ataxia battery scores of youths with a bipolar parent to those of healthy youths...
  33. ncbi request reprint Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1
    Yang Tang
    Department of Neurology, University of Cincinnati, Vontz Center, Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267 0536, USA
    Brain Res Mol Brain Res 132:155-67. 2004
    ....
  34. doi request reprint Rare autosomal dominant POLG1 mutation in a family with metabolic strokes, posterior column spinal degeneration, and multi-endocrine disease
    Sarah E Hopkins
    Divisions of Neurology, Cincinnati Children s Hospital Medical Center, and Pathology University of Cincinnati, Ohio, USA
    J Child Neurol 25:752-6. 2010
    ..We discuss novel aspects of their presentation and implications for practice...
  35. ncbi request reprint Genomic abnormalities in patients with migraine and chronic migraine: preliminary blood gene expression suggests platelet abnormalities
    Andrew D Hershey
    Children s Hospital Medical Center, Department of Neurology, Cincinnati, OH, USA
    Headache 44:994-1004. 2004
    ..It is hypothesized that gene expression changes in peripheral blood cells can be used to detect the interaction of these influences...
  36. ncbi request reprint Atomoxetine treatment of ADHD in children with comorbid Tourette syndrome
    Thomas J Spencer
    Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114 2696, USA
    J Atten Disord 11:470-81. 2008
    ..This study examines changes in severity of tics and ADHD during atomoxetine treatment in ADHD patients with Tourette syndrome (TS)...
  37. ncbi request reprint Pharmacodynamics of ziprasidone in children and adolescents: impact on dopamine transmission
    Floyd R Sallee
    Pharmacology Research Center, Children s Hospital Medical Center, USA
    J Am Acad Child Adolesc Psychiatry 42:902-7. 2003
    ..It is also an agonist at 5-HT(1A), which has been shown in rats to increase dopamine in prefrontal cortex. The objective of this study was to probe the dopamine agonist and antagonist pharmacodynamic properties of ziprasidone in youth...
  38. ncbi request reprint Epileptiform discharges and the behavior of children with epilepsy
    Donald L Gilbert
    J Pediatr 149:283; author reply 284. 2006
  39. ncbi request reprint Sequence variants in SLITRK1 are associated with Tourette's syndrome
    Jesse F Abelson
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Science 310:317-20. 2005
    ..Wild-type SLITRK1, but not the frameshift mutant, enhanced dendritic growth in primary neuronal cultures. Collectively, these findings support the association of rare SLITRK1 sequence variants with TS...
  40. ncbi request reprint Genomics of brain and blood: progress and pitfalls
    Frank R Sharp
    Department of Neurology and the M I N D Institute, University of California at Davis, Sacramento, California 95817, USA
    Epilepsia 47:1603-7. 2006
    ..Gene expression profiles in brain and blood of animals and humans can be useful for diagnosis, prognosis, and treatment of epilepsy. This article reviews recent progress and prospects for the future...
  41. ncbi request reprint Transcranial magnetic stimulation in children
    Marjorie A Garvey
    Pediatric Movement Disorders Unit, Human Motor Control Section, MNB, NINDS, 10 Center Drive, Room 5N226, MSC 1428, Bethesda, MD 20892 1428, USA
    Eur J Paediatr Neurol 8:7-19. 2004
    ..It will also briefly touch on the potential of TMS as a diagnostic tool in neurological disorders. It will not address the use of repetitive TMS in children...
  42. ncbi request reprint Low and high-frequency repetitive transcranial magnetic stimulation for the treatment of spasticity
    Donald L Gilbert
    Dev Med Child Neurol 49:486. 2007
  43. ncbi request reprint Interobserver reliability of visual interpretation of electroencephalograms in children with newly diagnosed seizures
    Donald L Gilbert
    Dev Med Child Neurol 48:1009-10; author reply 1010-1. 2006
  44. ncbi request reprint Regarding "omega-3 fatty acids supplementation in children with autism: a double-blind randomized, placebo-controlled pilot study"
    Donald L Gilbert
    Biol Psychiatry 63:e13; author reply e15. 2008