Research Topics
Genomes and Genes | James P FranciosiSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Quality of life in paediatric eosinophilic oesophagitis: what is important to patients?J P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Child Care Health Dev 38:477-83. 2012..The primary objective of this study was to identify key patient-reported and parent proxy outcome elements of EoE disease-specific HRQOL...
Eosinophilic esophagitisJames P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, 3333 Burnet Avenue, ML 2010, Cincinnati, OH 45229, USA
Immunol Allergy Clin North Am 29:19-27, viii. 2009..Referral to an allergist and food allergen testing is recommended. Dietary and topical corticosteroid therapies are commonly used and are effective in the majority of patients...
Development of a validated patient-reported symptom metric for pediatric eosinophilic esophagitis: qualitative methodsJames P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
BMC Gastroenterol 11:126. 2011..We sought to identify and validate key patient self-reported and parent proxy-reported outcomes (PROs) specific to EoE...
Long-term outcomes in pediatric-onset esophageal eosinophiliaCharles W Debrosse
Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
J Allergy Clin Immunol 128:132-8. 2011..Pediatric eosinophilic esophagitis (EoE) is a newly recognized antigen-induced form of chronic esophagitis (CE)...
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitisJoseph D Sherrill
Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
J Allergy Clin Immunol 126:160-5.e3. 2010..In addition, the genetic contributions of other allergy-associated genes to EE risk have not been explored...
A striking local esophageal cytokine expression profile in eosinophilic esophagitisCarine Blanchard
Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
J Allergy Clin Immunol 127:208-17, 217.e1-7. 2011..Eosinophilic esophagitis (EE) is an emerging worldwide disease that mimics gastroesophageal reflux disease...
Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitisCarol J Henderson
Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3039, USA
J Allergy Clin Immunol 129:1570-8. 2012..Eosinophilic esophagitis is a chronic, immune-mediated inflammatory disorder that responds to dietary therapy; however, data evaluating the effectiveness of dietary therapeutic strategies are limited...
Development of the Pediatric Quality of Life Inventory™ Eosinophilic Esophagitis module items: qualitative methodsJames P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, Nemours Children s Hospital, 13535 Nemours Parkway, Orlando, FL 32827, USA
BMC Gastroenterol 12:135. 2012..Therefore, the objective of this qualitative study was to further develop and finalize the items and support the content validity for the new Pediatric Quality of Life Inventory™ (PedsQL™) Eosinophilic Esophagitis Module...
Behavioral functioning and treatment adherence in pediatric eosinophilic gastrointestinal disordersKevin A Hommel
Center for the Promotion of Treatment Adherence and Self Management, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Pediatr Allergy Immunol 23:494-9. 2012..To examine behavioral predictors of treatment adherence in patients with eosinophilic gastrointestinal disorders (EGID)...
MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkersThomas X Lu
Division of Allergy and Immunology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
J Allergy Clin Immunol 129:1064-75.e9. 2012..The role of microRNAs (miRNAs), a key class of regulators of mRNA expression and translation, in patients with eosinophilic esophagitis (EoE) has not been explored...
Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999Charles W Debrosse
Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
J Allergy Clin Immunol 126:112-9. 2010..Eosinophilic esophagitis (EE) is now a commonly encountered disorder that was rarely diagnosed a decade ago...
Treatment adherence in pediatric eosinophilic gastrointestinal disordersKevin A Hommel
Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Pediatr Psychol 37:533-42. 2012..Examine treatment adherence rates in pediatric eosinophilic gastrointestinal disorders (EGID)...
Behavioral feeding problems and parenting stress in eosinophilic gastrointestinal disorders in childrenYelena P Wu
Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Pediatr Allergy Immunol 23:730-5. 2012..However, little is known about child and family functioning and adaptation and the impact of psychosocial functioning (e.g., behavioral feeding problems) on adherence to dietary restrictions in this pediatric population...
Changing indications for upper endoscopy in children during a 20-year periodJames P Franciosi
Cincinnati Children s Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati, OH 45229, USA
J Pediatr Gastroenterol Nutr 51:443-7. 2010..The aim of this study was to identify changes in subject characteristics and endoscopic procedures during a 20-year interval in children undergoing EGD at a single center...
Common variants at 5q22 associate with pediatric eosinophilic esophagitisMarc E Rothenberg
Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
Nat Genet 42:289-91. 2010..These data implicate the 5q22 locus in the pathogenesis of EoE and identify TSLP as the most likely candidate gene in the region...
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitisCarine Blanchard
Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
J Immunol 184:4033-41. 2010..These results establish that the epithelial response in EE involves a cooperative interaction between IL-13 and expression of EDC genes...
A case-control study of sociodemographic and geographic characteristics of 335 children with eosinophilic esophagitisJames P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Clin Gastroenterol Hepatol 7:415-9. 2009..The epidemiology of pediatric eosinophilic esophagitis (EE) is poorly characterized. In this study, we aimed to determine demographic, socioeconomic, and geographic characteristics of our cohort of EE children...
