Research Topics
| Tibor FarkasSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Molecular detection of novel astroviruses in wild and laboratory miceTibor Farkas
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Virus Genes 45:518-25. 2012..The relevance of astrovirus infection and its effect on biomedical research conducted in mice needs to be investigated...
Molecular detection of murine noroviruses in laboratory and wild miceTibor Farkas
Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA Electronic address
Vet Microbiol 160:463-7. 2012..This study provides further evidence for the circulation of novel, genetically diverse MNVs in wild mice...
Molecular detection of novel picornaviruses in chickens and turkeysTibor Farkas
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, ML7017, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Virus Genes 44:262-72. 2012..In summary, we report the molecular detection of novel picornaviruses that appear to be endemic in both chickens and turkeys...
Genetic diversity and histo-blood group antigen interactions of rhesus enteric calicivirusesTibor Farkas
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Virol 84:8617-25. 2010....
Detection of norovirus-, sapovirus- and rhesus enteric calicivirus-specific antibodies in captive juvenile macaquesTibor Farkas
Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Gen Virol 91:734-8. 2010..The high prevalence of human and rhesus CV-specific serum antibodies suggests the frequent exposure of colony macaques to enteric CVs including the possibility of CV transmission between human and non-human primate hosts...
Characterization of a rhesus monkey calicivirus representing a new genus of CaliciviridaeTibor Farkas
Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Virol 82:5408-16. 2008..Although the pathogenicity of TV in rhesus macaques remains to be elucidated, the likelihood of TV causing intestinal infection and the availability of a tissue culture system make this virus a valuable surrogate for human CVs...
Development of an enzyme immunoassay for detection of sapovirus-specific antibodies and its application in a study of seroprevalence in childrenTibor Farkas
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Clin Microbiol 44:3674-9. 2006..SV infection is common in the first 2 years of life. The low prevalence of maternal antibodies detected in Mexican children against SVs in this study is unique and needs to be addressed in future studies...
Seroprevalence of noroviruses in swineTibor Farkas
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
J Clin Microbiol 43:657-61. 2005....
Genetic diversity among sapovirusesT Farkas
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Arch Virol 149:1309-23. 2004....
Norovirus and histo-blood group antigens: demonstration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patternsPengwei Huang
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA
J Virol 79:6714-22. 2005..The high polymorphism of the human HBGA system, the involvement of multiple epitopes, and the typical protein/carbohydrate interaction between norovirus VLPs and HBGAs provide an explanation for the virus-ligand binding diversities...
Human milk contains elements that block binding of noroviruses to human histo-blood group antigens in salivaXi Jiang
Division of Infectious Diseases, Center for Epidemiology and Biostatistics, Department of Pediatrics, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3039, USA
J Infect Dis 190:1850-9. 2004..Secretor and Lewis, but not A or B antigens, were present in human milk and were responsible for blocking NV binding to receptors and therefore are likely to be decoy receptors that protect breast-fed infants from NV infection...
Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis studyMing Tan
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Virology 379:324-34. 2008..Taken together, our study provides new insights into the carbohydrate/capsid interactions which are a valuable complement to the atomic structures in understanding the virus/host interaction and in the future design of antiviral agents...
Homologous versus heterologous immune responses to Norwalk-like viruses among crew members after acute gastroenteritis outbreaks on 2 US Navy vesselsTibor Farkas
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Ohio 45229, USA
J Infect Dis 187:187-93. 2003..These results indicate that recombinant EIAs are useful for outbreak investigation and that the homologous antibody might be protective against reinfection...
Recovery of infectious virus by transfection of in vitro-generated RNA from tulane calicivirus cDNAChao Wei
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
J Virol 82:11429-36. 2008..The availability of the complete genomic sequence and the reverse genetics system described herein make TV a valuable model for studying calicivirus pathogenesis and replication...
Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patternsPengwei Huang
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA
J Infect Dis 188:19-31. 2003..Oligosaccharides containing the Lewis and ABH antigenic epitopes were involved in binding. Our findings suggest that different strains of NORs may recognize different human HBGAs on intestinal epithelial cells as receptors for infection...
Mutations within the P2 domain of norovirus capsid affect binding to human histo-blood group antigens: evidence for a binding pocketMing Tan
Division of Infectious Diseases and Division of Pediatric Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Virol 77:12562-71. 2003..Taken together, our data indicate that the binding pocket likely exists on NOR capsids. Direct evidence of this hypothesis requires crystallography studies...
Human milk oligosaccharides are associated with protection against diarrhea in breast-fed infantsArdythe L Morrow
Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
J Pediatr 145:297-303. 2004..To determine the association between maternal milk levels of 2-linked fucosylated oligosaccharide and prevention of diarrhea as a result of Campylobacter, caliciviruses, and diarrhea of all causes in breast-fed infants...
Human caliciviruses and pediatric gastroenteritisSarbelio Moreno-Espinosa
Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA
Semin Pediatr Infect Dis 15:237-45. 2004..Major developments in this field are expected to occur in the near future...
Human milk oligosaccharide blood group epitopes and innate immune protection against campylobacter and calicivirus diarrhea in breastfed infantsA L Morrow
Center for Epidemiology and Biostatistics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA
Adv Exp Med Biol 554:443-6. 2004
High incidence of rhesus enteric calicivirus infections and diarrhea in captive juvenile macaques: a likely associationTibor Farkas
Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Med Primatol 41:325-8. 2012..The rhesus enteric caliciviruses (ReCVs) were recently described...
Norovirus capsid protein expressed in yeast forms virus-like particles and stimulates systemic and mucosal immunity in mice following an oral administration of raw yeast extractsMing Xia
Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Med Virol 79:74-83. 2007..The mice immunization study also indicated that the oral administration of raw yeast extracts without an adjuvant is a safe and simple way which is worth to be studied for vaccine delivery in humans...
Molecular epidemiology of human calicivirus gastroenteritis outbreaks in Hungary, 1998 to 2000Gabor Reuter
Regional Laboratory of Virology, Baranya County Institute of State Public Health Service, Pecs, Hungary
J Med Virol 68:390-8. 2002..This is the first country-wide molecular epidemiological investigation of human calicivirus-associated, gastroenteritis outbreaks in Hungary and Central-Eastern Europe...
Detection of Norwalk-like virus infection aboard two U.S. Navy shipsScott Thornton
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, CA 92136, USA
Mil Med 167:826-30. 2002..No point source was found for either ship. The on-site laboratory investigation can provide important information for outbreak control and prevention while new cases are still presenting...
[Sapporo-like viruses in sporadic gastroenteritis of unknown origin]Gabor Reuter
Allami Népegészségügyi és Tisztiorvosi Szolgálat Baranya Megyei Intézete, Pecs, Regionális Virológiai Laboratórium
Orv Hetil 143:351-4. 2002..The etiologic role of these viruses is evident but little is known about the incidence of acute gastroenteritis caused by them. Sapporo-like viruses have not been detected in Hungary before...
Gastroenteritis in US Marines during Operation Iraqi FreedomScott A Thornton
Navy Environmental and Preventive Medicine Unit No 6, Pearl Harbor, Hawaii 96860, USA
Clin Infect Dis 40:519-25. 2005..A Navy Preventive Medicine laboratory was set up in Ad Diwaniyah, Iraq, to provide clinical diagnostic support for Marine medical units during a period of repositioning in south-central Iraq...
Seroprevalence of antibodies against noroviruses among students in a Chinese military medical universityYing-chun Dai
Department of Epidemiology, First Military Medical University, Guangzhou, China
J Clin Microbiol 42:4615-9. 2004..The distribution of ABO blood types did not differ among the three groups. These data suggest that NVs are prevalent in China and that both genetic and environmental factors play a role in NV infection...
Detection and analysis of transpositionally active head-to-tail dimers in three additional Escherichia coli IS elementsIldiko Szeverenyi
Environmental Biosafety Research Institute, Agricultural Biotechnology Centre, Szent Györgyi Albert str 4, H 2101 Gödöllõ, Hungary
Microbiology 149:1297-310. 2003..The results presented for IS3, IS150 and IS186 are in accordance with the IS dimer model, which is in turn consistent with models based on covalently closed minicircles...
Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipidsGwendolyn Barcelo-Coblijn
Institute of Biochemistry and Laboratory of Functional Genomics, Biological Research Center, Hungarian Academy of Sciences, H 6726 Szeged, Hungary
Proc Natl Acad Sci U S A 100:11321-6. 2003..The results are interpreted in terms of the roles of different phospholipid molecular species in cognitive functions coupled with differential responsiveness of the genetic machinery of neurons to n-3 polyunsaturated fatty acids...
Real-time reverse transcription-polymerase chain reaction detection of Newcastle disease virus using light upon extension fluorogenic primersMárta Antal
Central Veterinary Institute, Institute of Debrecen, Bornemissza u 3 7, H 4031 Debrecen, Hungary
J Vet Diagn Invest 19:400-4. 2007..Due to its high specificity, sensitivity, and relative simplicity, the LUX RT-PCR assay provides a novel, rapid, and practical tool for the detection of NDV...
