Pirooz Eghtesady

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi Maternal-fetal interactions in fetal cardiac surgery
    Pirooz Eghtesady
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3032, USA
    Ann Thorac Surg 81:249-55; discussion 255-6. 2006
  2. doi Seasonality of hypoplastic left heart syndrome in the United States: a 10-year time-series analysis
    Pirooz Eghtesady
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital, Cincinnati, Ohio 45229 3039, USA
    J Thorac Cardiovasc Surg 141:432-8. 2011
  3. ncbi Hypoplastic left heart syndrome: Rheumatic heart disease of the fetus?
    Pirooz Eghtesady
    Division of Paediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Med Hypotheses 66:554-65. 2006
  4. ncbi Heparin-induced thrombocytopenia complicating support by the Berlin Heart
    Pirooz Eghtesady
    Division of Pediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    ASAIO J 51:820-5. 2005
  5. ncbi Revisiting animal models of aortic stenosis in the early gestation fetus
    Pirooz Eghtesady
    Division of Pediatric Cardiac Surgery and Pediatric Cardiology, University of Cincinnati College of Medicine and Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Ann Thorac Surg 83:631-9. 2007
  6. ncbi A simple solution is "prime" for fetal cardiopulmonary bypass
    R Scott Baker
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Ohio 45229 3039, USA
    ASAIO J 53:710-5. 2007
  7. doi Application of near-infrared spectroscopy during fetal cardiac surgery
    Casey A Reed
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3032, USA
    J Surg Res 171:159-63. 2011
  8. doi Low weight-for-age z-score and infection risk after the Fontan procedure
    Jeffrey B Anderson
    Division of Cardiology, Cincinnati Children s Hospital Medical Center, The Heart Institute, Cincinnati, Ohio 45255, USA
    Ann Thorac Surg 91:1460-6. 2011
  9. doi Fetal stress response to fetal cardiac surgery
    Christopher T Lam
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3032, USA
    Ann Thorac Surg 85:1719-27. 2008
  10. ncbi Vacuum-assisted venous drainage during fetal cardiopulmonary bypass
    Walter C Lubbers
    Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH, USA
    ASAIO J 51:644-8. 2005

Research Grants

Collaborators

Detail Information

Publications29

  1. ncbi Maternal-fetal interactions in fetal cardiac surgery
    Pirooz Eghtesady
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3032, USA
    Ann Thorac Surg 81:249-55; discussion 255-6. 2006
    ..We examined potential maternal-fetal interactions during fetal cardiopulmonary bypass. these interactions, not previously described, may significantly influence attempts at fetal cardiac surgery...
  2. doi Seasonality of hypoplastic left heart syndrome in the United States: a 10-year time-series analysis
    Pirooz Eghtesady
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital, Cincinnati, Ohio 45229 3039, USA
    J Thorac Cardiovasc Surg 141:432-8. 2011
    ..The objective of this study was to examine seasonal and temporal patterns of hypoplastic left heart syndrome births compared with other left-sided heart defects in the United States...
  3. ncbi Hypoplastic left heart syndrome: Rheumatic heart disease of the fetus?
    Pirooz Eghtesady
    Division of Paediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Med Hypotheses 66:554-65. 2006
    ..Implications for other congenital heart diseases and the broader picture of global public health are discussed...
  4. ncbi Heparin-induced thrombocytopenia complicating support by the Berlin Heart
    Pirooz Eghtesady
    Division of Pediatric Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    ASAIO J 51:820-5. 2005
    ..We discuss the unique challenges posed by HIT II complicating pediatric VAD support and in relation to the heparin coating of the device...
  5. ncbi Revisiting animal models of aortic stenosis in the early gestation fetus
    Pirooz Eghtesady
    Division of Pediatric Cardiac Surgery and Pediatric Cardiology, University of Cincinnati College of Medicine and Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Ann Thorac Surg 83:631-9. 2007
    ..Fetal interventions are now being performed, based on the presumption that they would prevent such pathogenic mechanisms...
  6. ncbi A simple solution is "prime" for fetal cardiopulmonary bypass
    R Scott Baker
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Ohio 45229 3039, USA
    ASAIO J 53:710-5. 2007
    ..Calcium addition to the prime adversely affects fetal gas exchange worsening acidosis during fetal bypass. Bicarbonate addition to the prime is also detrimental to the fetus resulting in greater CO2 production and impaired hemodynamics...
  7. doi Application of near-infrared spectroscopy during fetal cardiac surgery
    Casey A Reed
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3032, USA
    J Surg Res 171:159-63. 2011
    ..We set out to test its feasibility as a monitor of fetal and placental oxygenation during fetal cardiac surgery...
  8. doi Low weight-for-age z-score and infection risk after the Fontan procedure
    Jeffrey B Anderson
    Division of Cardiology, Cincinnati Children s Hospital Medical Center, The Heart Institute, Cincinnati, Ohio 45255, USA
    Ann Thorac Surg 91:1460-6. 2011
    ..We sought to assess growth status at the time of the Fontan procedure and the effect of poor growth status on surgical outcomes...
  9. doi Fetal stress response to fetal cardiac surgery
    Christopher T Lam
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3032, USA
    Ann Thorac Surg 85:1719-27. 2008
    ..We set out to characterize this fetal stress response and its potential role in placental dysfunction...
  10. ncbi Vacuum-assisted venous drainage during fetal cardiopulmonary bypass
    Walter C Lubbers
    Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH, USA
    ASAIO J 51:644-8. 2005
    ..VAVD can be safely applied during fetal bypass provided pressures are kept < or = -20 mm Hg. However, the achieved higher flow rates do not prevent postbypass placental dysfunction and may indeed be detrimental to the fetus...
  11. ncbi Role of nitric oxide pathway in placental dysfunction following fetal bypass
    Christopher Lam
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Ann Thorac Surg 84:917-24; discussion 924-5. 2007
    ..The placental nitric oxide (NO) pathway has been implicated in this pathophysiology. We set out to examine possible perturbations in this pathway in an ovine model of fetal bypass...
  12. pmc Myocardial function after fetal cardiac bypass in an ovine model
    Jodie Y Duffy
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Thorac Cardiovasc Surg 141:961-8, 968.e1. 2011
    ..The hypothesis was that fetal cardiac bypass results in myocardial dysfunction, possibly because of perturbation of calcium cycling and contractile proteins...
  13. ncbi Cardiopulmonary bypass in the immature fetus through novel use of a mini-centrifugal pump
    John Lombardi
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Perfusion 21:185-91. 2006
    ..Finally, while previous fetal experiments have used late-gestation mature fetuses, we studied more immature fetuses of mid-gestation, relevant to current clinical attempts in fetal therapy...
  14. doi Changes in fetal ovine metabolism and oxygen delivery with fetal bypass
    Christopher T Lam
    Division of Cardiothoracic Surgery, Cincinnati Children s Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229 3032, USA
    Am J Physiol Regul Integr Comp Physiol 301:R105-15. 2011
    ..These initial findings warrant further investigation of interventions to restore metabolic and hemodynamic homeostasis after fetal bypass...
  15. doi Factors affecting long-term risk of aortic arch recoarctation after the Norwood procedure
    Traci M Ashcraft
    Division of Cardiothoracic Surgery, The Heart Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Ann Thorac Surg 85:1397-401; discussion 1401-2. 2008
    ..The purpose of this study was to identify factors predicting risk of aortic arch recoarctation after the Norwood procedure...
  16. ncbi Dynamic fluid shifts induced by fetal bypass
    R Scott Baker
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Thorac Cardiovasc Surg 137:714-22. 2009
    ..The degree or mechanisms behind these volume changes (or location) have not been defined. We characterized the preceding and correlated the findings to plasma vasopressin concentrations, the critical peptide of osmoregulation...
  17. doi Predictors of poor weight gain in infants with a single ventricle
    Jeffrey B Anderson
    Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Pediatr 157:407-13, 413.e1. 2010
    ..To assess growth from the time of neonatal discharge to the time of performance of the bidirectional Glenn (BDG) procedure in infants with a single ventricle and determine predictors of poor growth...
  18. doi Fetal right ventricular myocardial function is better preserved by fibrillatory arrest during fetal cardiac bypass
    Orlando Petrucci
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Ann Thorac Surg 90:1324-31. 2010
    ..Protection and preservation of fetal myocardial function are important for successful fetal intracardiac repair. Our objective was to determine fetal biventricular cardiac performance after two cardiac-arrest techniques...
  19. doi Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle
    Jeffrey B Anderson
    Division of Cardiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45259, USA
    J Thorac Cardiovasc Surg 138:397-404.e1. 2009
    ..We sought to assess the effect of nutritional status at the time of the bidirectional Glenn procedure on short-term outcomes...
  20. doi Role of natriuretic peptides in cGMP production in fetal cardiac bypass
    Emily A Heeb
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Ann Thorac Surg 87:841-7. 2009
    ..We hypothesized that these natriuretic peptides may account for the paradoxic rise in cGMP seen with fetal bypass...
  21. ncbi Anesthetic techniques for fetal surgery: effects of maternal anesthesia on intraoperative fetal outcomes in a sheep model
    Pornswan Ngamprasertwong
    Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Anesthesiology 118:796-808. 2013
    ..In this animal study, the authors compare maternal-fetal effects of high-dose desflurane anesthesia (HD-DES) and SIVA...
  22. ncbi Fetal aortic stenosis and changes in amniotic fluid natriuretic peptides
    Walter C Lubbers
    Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH, USA
    Am J Obstet Gynecol 196:253.e1-6. 2007
    ..We studied their usefulness, based on amniotic fluid concentrations, in an ovine model of fetal aortic stenosis and in response to fetal cardiac intervention...
  23. ncbi Prioritizing quality improvement in pediatric cardiac surgery
    Pirooz Eghtesady
    Division of Pediatric Cardiothoracic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Thorac Cardiovasc Surg 145:631-9; discussion 639-40. 2013
    ....
  24. ncbi Congenital heart disease linked to maternal autoimmunity against cardiac myosin
    Charles R Cole
    Division of Molecular Cardiovascular Biology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229
    J Immunol 192:4074-82. 2014
    ..To our knowledge, this report shows the first evidence in support of a novel immune-mediated mechanism for pathogenesis of structural CHD that may have implications in its future diagnosis and treatment. ..
  25. ncbi Infant arch reconstruction during total system perfusion
    Aimee B Gardner
    Cincinnati Children s Hospital Medical Center, Cardiothoracic Surgery, Cincinnati, Ohio 45229, USA
    J Thorac Cardiovasc Surg 133:1096-8. 2007
  26. doi Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplasty
    Jenni Raake
    Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Respir Care 56:1198-202. 2011
    ..This strategy of ECMO with extubation, then high-frequency oscillatory ventilation is a useful rescue therapy in patients with postoperative tracheal dehiscence...
  27. pmc Use of a ventricular assist device in a single-ventricle patient
    Pirooz Eghtesady
    Tex Heart Inst J 32:618; author reply 618-9. 2005
  28. ncbi Harmful effects of fentanyl on the fetus and placenta?
    Joseph A Sedgwick
    Am J Obstet Gynecol 193:303-4; author reply 304. 2005
  29. ncbi Studies of fetal cardiac bypass
    Joseph A Sedgwick
    J Thorac Cardiovasc Surg 129:235-6; author reply 236. 2005

Research Grants1

  1. Hypoplastic Left Heart Syndrome: Expression of RHD in the Fetus?
    Pirooz Eghtesady; Fiscal Year: 2010
    ..If proven true, the findings will have a profound impact on this disease and the lives of many mothers and their affected babies. ..