Research Topics
Genomes and Genes
Species | Sudhansu K DeySummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Uterine deletion of Trp53 compromises antioxidant responses in the mouse deciduaKristin E Burnum
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352 9104, USA
Endocrinology 153:4568-79. 2012..In particular, down-regulation of a cluster of antioxidant enzymes in p53-deficient deciduae suggests that increased oxidative stress could be one cause of preterm birth in mice harboring uterine deletion of Trp53...
Galectin-1 markedly reduces the incidence of resorptions in mice missing immunophilin FKBP52Yasushi Hirota
Department of Obstetrics and Gynecology, University of Tokyo, Tokyo 113 8655, Japan
Endocrinology 153:2486-93. 2012..These findings suggest that uterine Gal1 is an important downstream target of P(4)-FKBP52-PR signaling in the uterus to support P(4) responsiveness during pregnancy...
How we are bornSudhansu K Dey
Cincinnati Children s Research Foundation, Division of Reproductive Sciences, MLC 7045, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
J Clin Invest 120:952-5. 2010....
Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivityTakiko Daikoku
Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Dev Cell 21:1014-25. 2011....
Heightened uterine mammalian target of rapamycin complex 1 (mTORC1) signaling provokes preterm birth in miceYasushi Hirota
Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children s Research Foundation, Cincinnati, OH 45229, USA
Proc Natl Acad Sci U S A 108:18073-8. 2011..This role of mTORC1 signaling in determining the timing of birth in mice may help us better understand the mechanism of the timing of birth in humans and develop new and improved strategies to combat the global problem of preterm birth...
Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantationXiaofei Sun
Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Proc Natl Acad Sci U S A 109:1145-50. 2012..This is associated with the retention of the epithelium around the implantation chamber with arrested embryonic growth. These results suggest that Klf5 is indispensable for normal implantation...
Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stressYasushi Hirota
Division of Reproductive Sciences, The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Proc Natl Acad Sci U S A 107:15577-82. 2010..This study shows that FKBP52-PRDX6 signaling protects pregnancy from overt OS...
Endocannabinoid signaling directs differentiation of trophoblast cell lineages and placentationXiaofei Sun
Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Proc Natl Acad Sci U S A 107:16887-92. 2010....
Cell-specific conditional deletion of Pten in the uterus results in differential phenotypesTakiko Daikoku
Division of Reproductive Sciences, The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
Gynecol Oncol 122:424-9. 2011..Our objective was to determine whether deletion of Pten specifically in the uterine stroma and myometrium induces cancer or manifests different phenotypes...
Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in miceYasushi Hirota
The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Ohio, USA
J Clin Invest 120:803-15. 2010..Taken together, our observations underscore what we believe to be a new critical role of uterine p53 in parturition...
Endocannabinoid signaling in female reproductionXiaofei Sun
Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, United States
ACS Chem Neurosci 3:349-55. 2012..This review focuses on various aspects of endocannabinoid signaling in female fertility...
Cannabinoid/Endocannabinoid signaling impact on early pregnancy eventsXiaofei Sun
Reproductive Sciences, Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, 45229, USA
Curr Top Behav Neurosci 1:255-73. 2009..This review summarizes some aspects of these signaling molecules in preimplantation and implantation biology utilizing genetically engineered mouse models...
