Tony DeFalco

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. DeFalco T, Bhattacharya I, Williams A, Sams D, Capel B. Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis. Proc Natl Acad Sci U S A. 2014;111:E2384-93 pubmed publisher
    ..These findings reveal a previously unappreciated role for macrophages in testis morphogenesis and suggest that macrophages are an intermediary between neovascularization and organ architecture during fetal organogenesis. ..
  2. Kumar D, DeFalco T. A perivascular niche for multipotent progenitors in the fetal testis. Nat Commun. 2018;9:4519 pubmed publisher
  3. DeFalco T, Potter S, Williams A, Waller B, Kan M, Capel B. Macrophages Contribute to the Spermatogonial Niche in the Adult Testis. Cell Rep. 2015;12:1107-19 pubmed publisher
    ..These findings reveal an unexpected role for macrophages in the spermatogonial niche in the testis and raise the possibility that macrophages play previously unappreciated roles in stem/progenitor cell regulation in other tissues. ..
  4. Potter S, DeFalco T. Using Ex Vivo Upright Droplet Cultures of Whole Fetal Organs to Study Developmental Processes during Mouse Organogenesis. J Vis Exp. 2015;:e53262 pubmed publisher
    ..This organ culture system provides flexibility in experimentation with fetal organs, and results obtained using this technique will help researchers gain insights into fetal development. ..
  5. Potter S, Kumar D, DeFalco T. Origin and Differentiation of Androgen-Producing Cells in the Gonads. Results Probl Cell Differ. 2016;58:101-34 pubmed publisher
  6. Potter S, DeFalco T. Role of the testis interstitial compartment in spermatogonial stem cell function. Reproduction. 2017;153:R151-R162 pubmed publisher
    ..Overall, SSC interactions with interstitial and peritubular cells are critical for SSC function and are an important underlying factor promoting male fertility. ..

Collaborators