SANJOY KUMAR DAS

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi Epigenetic changes through DNA methylation contribute to uterine stromal cell decidualization
    Fei Gao
    Division of Reproductive Sciences and Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Endocrinology 153:6078-90. 2012
  2. ncbi Overexpression of cyclin D3 improves decidualization defects in Hoxa-10(-/-) mice
    Julie M Sroga
    Obstetrics and Gynecology, University of Cincinnati, Ohio 45267, USA
    Endocrinology 153:5575-86. 2012
  3. ncbi Nucleolar Sik-similar protein (Sik-SP) is required for the maintenance of uterine estrogen signaling mechanism via ERα
    Daesuk Chung
    Division of Reproductive Sciences, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    Mol Endocrinol 26:385-98. 2012
  4. ncbi Regional development of uterine decidualization: molecular signaling by Hoxa-10
    Sanjoy K Das
    Reproductive Sciences, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Mol Reprod Dev 77:387-96. 2010
  5. ncbi Cell cycle regulatory control for uterine stromal cell decidualization in implantation
    Sanjoy K Das
    Reproductive Sciences, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Reproduction 137:889-99. 2009
  6. ncbi GPR30 activation opposes estrogen-dependent uterine growth via inhibition of stromal ERK1/2 and estrogen receptor alpha (ERα) phosphorylation signals
    Fei Gao
    Division of Reproductive Sciences, The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Endocrinology 152:1434-47. 2011
  7. ncbi Hoxa-10 deficiency alters region-specific gene expression and perturbs differentiation of natural killer cells during decidualization
    Mohammad A Rahman
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Dev Biol 290:105-17. 2006
  8. ncbi Cyclin G1 and cyclin G2 are expressed in the periimplantation mouse uterus in a cell-specific and progesterone-dependent manner: evidence for aberrant regulation with Hoxa-10 deficiency
    Limin Yue
    Division of Reproductive and Developmental Biology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Endocrinology 146:2424-33. 2005
  9. ncbi Mouse primary uterine cell coculture system revisited: ovarian hormones mimic the aspects of in vivo uterine cell proliferation
    Daesuk Chung
    Division of Reproductive Sciences, The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Endocrinology 152:3246-58. 2011
  10. ncbi Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success
    Haibin Wang
    Department of Pediatrics, Division of Reproductive and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Biol Chem 282:37770-82. 2007

Research Grants

  1. ENVIRONMENTAL TOXINS AND UTERINE GENE EXPRESSION
    SANJOY KUMAR DAS; Fiscal Year: 2010
  2. Molecular Signaling in Decidualization
    Sanjoy Das; Fiscal Year: 2009
  3. ENVIRONMENTAL TOXINS AND UTERINE GENE EXPRESSION
    Sanjoy Das; Fiscal Year: 2007
  4. ASPECTS OF UTERINE CELL CYCLE REGULATION IN IMPLANTATION
    Sanjoy Das; Fiscal Year: 2005
  5. Molecular Signaling in Decidualization
    SANJOY KUMAR DAS; Fiscal Year: 2010

Collaborators

  • W Wahli
  • Fei Gao
  • Daesuk Chung
  • Haibin Wang
  • Sudhansu K Dey
  • Xinghong Ma
  • Julie M Sroga
  • Alicia B Ostmann
  • Takiko Daikoku
  • Xiaonan Hou
  • Huirong Xie
  • Hao Zhang
  • Mohammad A Rahman
  • Meiling Li
  • Limin Yue
  • Xiaohong Wang
  • Alicia Ostmann
  • Allison Rusie
  • Jennifer Hemingway
  • Beatrice Desvergne
  • Dingzhi Wang
  • Xiangxu Jia
  • Raymond N DuBois
  • Susanne Tranguch
  • Xiaofei Sun
  • Ping Li
  • Hiroshi Nojima
  • Hiromichi Matsumoto
  • Sietse Mosselman
  • Xuemei Zhao
  • Haengseok Song
  • Yong Guo
  • Bibhash C Paria
  • Anne Riesewijk

Detail Information

Publications13

  1. ncbi Epigenetic changes through DNA methylation contribute to uterine stromal cell decidualization
    Fei Gao
    Division of Reproductive Sciences and Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Endocrinology 153:6078-90. 2012
    ..Overall, these results suggest that uterine DNM plays a major role for successful decidualization and embryo development during early pregnancy...
  2. ncbi Overexpression of cyclin D3 improves decidualization defects in Hoxa-10(-/-) mice
    Julie M Sroga
    Obstetrics and Gynecology, University of Cincinnati, Ohio 45267, USA
    Endocrinology 153:5575-86. 2012
    ..Collectively, these results demonstrate that cyclin D3 expression influences a host of genes involved in decidualization and can improve decidualization in Hoxa-10(-/-) mice...
  3. ncbi Nucleolar Sik-similar protein (Sik-SP) is required for the maintenance of uterine estrogen signaling mechanism via ERα
    Daesuk Chung
    Division of Reproductive Sciences, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    Mol Endocrinol 26:385-98. 2012
    ..In conclusion, Sik-SP, an early E2-responsive nucleolar protein, is necessary to induce E2-dependent ERα-mediated appropriate physiologic responses in the uterus...
  4. ncbi Regional development of uterine decidualization: molecular signaling by Hoxa-10
    Sanjoy K Das
    Reproductive Sciences, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Mol Reprod Dev 77:387-96. 2010
    ..In this regard, this article provides an overview of potential signaling mechanisms mediated by Hoxa-10 that can influence a host of genes and cell functions necessary for propagating regional decidual development...
  5. ncbi Cell cycle regulatory control for uterine stromal cell decidualization in implantation
    Sanjoy K Das
    Reproductive Sciences, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Reproduction 137:889-99. 2009
    ..This review will aim to address the currently available knowledge on interaction between growth factor/homeobox and cell cycle regulatory signaling in the progression of various aspects of decidualization...
  6. ncbi GPR30 activation opposes estrogen-dependent uterine growth via inhibition of stromal ERK1/2 and estrogen receptor alpha (ERα) phosphorylation signals
    Fei Gao
    Division of Reproductive Sciences, The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Endocrinology 152:1434-47. 2011
    ..Our work has uncovered a novel GPR30-regulated inhibitory event, which may be physiologically relevant in both normal and pathological situations to negatively balance ERα-dependent uterine growth regulatory functions induced by E2...
  7. ncbi Hoxa-10 deficiency alters region-specific gene expression and perturbs differentiation of natural killer cells during decidualization
    Mohammad A Rahman
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Dev Biol 290:105-17. 2006
    ..Collectively, the results provide evidence that Hoxa-10 influences a host of genes and cell functions necessary for propagating normal decidual development during the post-implantation period...
  8. ncbi Cyclin G1 and cyclin G2 are expressed in the periimplantation mouse uterus in a cell-specific and progesterone-dependent manner: evidence for aberrant regulation with Hoxa-10 deficiency
    Limin Yue
    Division of Reproductive and Developmental Biology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Endocrinology 146:2424-33. 2005
    ....
  9. ncbi Mouse primary uterine cell coculture system revisited: ovarian hormones mimic the aspects of in vivo uterine cell proliferation
    Daesuk Chung
    Division of Reproductive Sciences, The Perinatal Institute, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Endocrinology 152:3246-58. 2011
    ....
  10. ncbi Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success
    Haibin Wang
    Department of Pediatrics, Division of Reproductive and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Biol Chem 282:37770-82. 2007
    ..This study is clinically relevant because deferral of on time implantation leads to spontaneous pregnancy loss, and defective trophoblast invasion is one cause of preeclampsia in humans...
  11. ncbi Conditional gene recombination by adenovirus-driven Cre in the mouse uterus
    Haibin Wang
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2678, USA
    Genesis 44:51-6. 2006
    ..These findings demonstrate the feasibility of achieving conditional expression or deletion of specific genes in uterine cells at desired times and physiological states...
  12. ncbi Uterine Msx-1 and Wnt4 signaling becomes aberrant in mice with the loss of leukemia inhibitory factor or Hoxa-10: evidence for a novel cytokine-homeobox-Wnt signaling in implantation
    Takiko Daikoku
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2678, USA
    Mol Endocrinol 18:1238-50. 2004
    ..Collectively, the present results provide evidence for a novel cytokine-homeotic-Wnt signaling network in implantation...
  13. ncbi Embryonic signals direct the formation of tight junctional permeability barrier in the decidualizing stroma during embryo implantation
    Xiaohong Wang
    Department of Pediatrics, Division of Reproductive and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232-2678, USA
    J Cell Sci 117:53-62. 2004
    ..These findings suggest that trophoblast-induced expression of tight junctions forms a temporary barrier in cells of the primary decidual zone that restricts the passage of injurious stimuli such as maternal immunoglobulins to the embryo...

Research Grants15

  1. ENVIRONMENTAL TOXINS AND UTERINE GENE EXPRESSION
    SANJOY KUMAR DAS; Fiscal Year: 2010
    ..Overall, the results will help us to define the relationship and a molecular cross-talk between the two-phase estrogenic responses in the uterus. ..
  2. Molecular Signaling in Decidualization
    Sanjoy Das; Fiscal Year: 2009
    ..abstract_text> ..
  3. ENVIRONMENTAL TOXINS AND UTERINE GENE EXPRESSION
    Sanjoy Das; Fiscal Year: 2007
    ..The results will help us define the relationship and a molecular cross-talk between the two-phase estrogenic responses in the uterus. ..
  4. ASPECTS OF UTERINE CELL CYCLE REGULATION IN IMPLANTATION
    Sanjoy Das; Fiscal Year: 2005
    ..Since these processes are analogous to pseudomalignancy, the results should also provide basic information relevant to cancer biology. ..
  5. Molecular Signaling in Decidualization
    SANJOY KUMAR DAS; Fiscal Year: 2010
    ..abstract_text> ..