- Digital sorting of complex tissues for cell type-specific gene expression profilesYi Zhong
Department of Pediatrics, Neurological Research Institute, Baylor College of Medicine, Houston, TX, USA
BMC Bioinformatics 14:89. 2013..Standard deconvolution algorithms require prior knowledge of the cell type frequencies within a tissue or their in vitro expression profiles. Furthermore, these algorithms tend to report biased estimations...
- Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse modelsLionel M L Chow
Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Oncotarget 3:67-77. 2012..As we learn more about the biology of high-grade astrocytoma from the study of these models, we anticipate that our improved understanding will eventually lead to greater success in clinical trials and improved outcome for patients...