Ranjit S Chima

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. doi request reprint Improved outcomes for stem cell transplant recipients requiring pediatric intensive care
    Ranjit S Chima
    Divisions of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Crit Care Med 13:e336-42. 2012
  2. doi request reprint Advances in critical care of the pediatric hematopoietic stem cell transplant patient
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatr Clin North Am 60:689-707. 2013
  3. doi request reprint Reduction in hypoglycemic events in critically ill patients on continuous insulin following implementation of a treatment guideline
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Qual Manag Health Care 21:20-8. 2012
  4. pmc C-peptide ameliorates kidney injury following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Shock 35:524-9. 2011
  5. pmc C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine MLC 2005 Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Am J Physiol Lung Cell Mol Physiol 300:L730-9. 2011
  6. pmc Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 36:2849-57. 2008
  7. pmc Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati, OH, USA
    Int J Clin Exp Med 3:1-9. 2010
  8. doi request reprint Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplasty
    Jenni Raake
    Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Respir Care 56:1198-202. 2011
  9. pmc Validation of a gene expression-based subclassification strategy for pediatric septic shock
    Hector R Wong
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 39:2511-7. 2011
  10. pmc Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept
    Hector R Wong
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 38:1955-61. 2010

Detail Information

Publications10

  1. doi request reprint Improved outcomes for stem cell transplant recipients requiring pediatric intensive care
    Ranjit S Chima
    Divisions of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Crit Care Med 13:e336-42. 2012
    ..This study was conducted to review outcomes for patients undergoing hematopoietic stem cell transplantation requiring admission to our pediatric intensive care unit and to identify variables impacting survival...
  2. doi request reprint Advances in critical care of the pediatric hematopoietic stem cell transplant patient
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatr Clin North Am 60:689-707. 2013
    ..Hence, familiarity with recent advances in the transplant process and complications is crucial for the intensivist. This article will highlight common complications encountered in the critically ill SCT recipient...
  3. doi request reprint Reduction in hypoglycemic events in critically ill patients on continuous insulin following implementation of a treatment guideline
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Qual Manag Health Care 21:20-8. 2012
    ..However, the incidence of hypoglycemia while attempting glycemic control using an insulin infusion may be as high as 25% and hypoglycemia may be an independent risk factor for mortality in critically ill children...
  4. pmc C-peptide ameliorates kidney injury following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Shock 35:524-9. 2011
    ..Thus, our data suggest that C-peptide may exert renoprotective effects after hemorrhagic shock by modulating activator protein 1 signaling...
  5. pmc C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine MLC 2005 Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Am J Physiol Lung Cell Mol Physiol 300:L730-9. 2011
    ..Our data suggest that C-peptide ameliorates the inflammatory response and lung inflammation following hemorrhagic shock. These effects may be modulated by altering the balance between pro- and anti-inflammatory signaling in the lung...
  6. pmc Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 36:2849-57. 2008
    ..We investigated the effects of ciglitazone on lung inflammation after severe hemorrhage...
  7. pmc Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati, OH, USA
    Int J Clin Exp Med 3:1-9. 2010
    ..This was associated with increased phosphorylation of the pro-survival kinase Akt. Thus, our data suggest that ciglitazone, a PPARy ligand, promotes cell survival in the lung following hemorrhagic shock...
  8. doi request reprint Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplasty
    Jenni Raake
    Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Respir Care 56:1198-202. 2011
    ..This strategy of ECMO with extubation, then high-frequency oscillatory ventilation is a useful rescue therapy in patients with postoperative tracheal dehiscence...
  9. pmc Validation of a gene expression-based subclassification strategy for pediatric septic shock
    Hector R Wong
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 39:2511-7. 2011
    ..Here we attempted to prospectively validate the existence of these gene expression-based subclasses in a validation cohort...
  10. pmc Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept
    Hector R Wong
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 38:1955-61. 2010
    ..To develop a clinically feasible stratification strategy for pediatric septic shock, using gene expression mosaics and a 100-gene signature representing the first 24 hrs of admission to the pediatric intensive care unit...