Ranjit S Chima

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi Reduction in hypoglycemic events in critically ill patients on continuous insulin following implementation of a treatment guideline
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Qual Manag Health Care 21:20-8. 2012
  2. ncbi C-peptide ameliorates kidney injury following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Shock 35:524-9. 2011
  3. ncbi C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine MLC 2005 Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Am J Physiol Lung Cell Mol Physiol 300:L730-9. 2011
  4. ncbi Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 36:2849-57. 2008
  5. ncbi Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati, OH, USA
    Int J Clin Exp Med 3:1-9. 2010
  6. ncbi Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept
    Hector R Wong
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 38:1955-61. 2010
  7. ncbi Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplasty
    Jenni Raake
    Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Respir Care 56:1198-202. 2011

Collaborators

Detail Information

Publications7

  1. ncbi Reduction in hypoglycemic events in critically ill patients on continuous insulin following implementation of a treatment guideline
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Qual Manag Health Care 21:20-8. 2012
    ..However, the incidence of hypoglycemia while attempting glycemic control using an insulin infusion may be as high as 25% and hypoglycemia may be an independent risk factor for mortality in critically ill children...
  2. ncbi C-peptide ameliorates kidney injury following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Shock 35:524-9. 2011
    ..Thus, our data suggest that C-peptide may exert renoprotective effects after hemorrhagic shock by modulating activator protein 1 signaling...
  3. ncbi C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine MLC 2005 Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Am J Physiol Lung Cell Mol Physiol 300:L730-9. 2011
    ..Our data suggest that C-peptide ameliorates the inflammatory response and lung inflammation following hemorrhagic shock. These effects may be modulated by altering the balance between pro- and anti-inflammatory signaling in the lung...
  4. ncbi Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 36:2849-57. 2008
    ..We investigated the effects of ciglitazone on lung inflammation after severe hemorrhage...
  5. ncbi Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock
    Ranjit S Chima
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati, OH, USA
    Int J Clin Exp Med 3:1-9. 2010
    ..This was associated with increased phosphorylation of the pro-survival kinase Akt. Thus, our data suggest that ciglitazone, a PPARy ligand, promotes cell survival in the lung following hemorrhagic shock...
  6. ncbi Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept
    Hector R Wong
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Crit Care Med 38:1955-61. 2010
    ..To develop a clinically feasible stratification strategy for pediatric septic shock, using gene expression mosaics and a 100-gene signature representing the first 24 hrs of admission to the pediatric intensive care unit...
  7. ncbi Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplasty
    Jenni Raake
    Heart Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Respir Care 56:1198-202. 2011
    ..This strategy of ECMO with extubation, then high-frequency oscillatory ventilation is a useful rescue therapy in patients with postoperative tracheal dehiscence...