Eric W Brunskill

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc RNA-Seq defines novel genes, RNA processing patterns and enhancer maps for the early stages of nephrogenesis: Hox supergenes
    Eric W Brunskill
    Children s Hospital Medical Center, Division of Developmental Biology, 3333 Burnet Ave Cincinnati, OH 452239, USA
    Dev Biol 368:4-17. 2012
  2. pmc Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production
    Eric W Brunskill
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center and the University of Cincinnati School of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    BMC Dev Biol 11:15. 2011
  3. pmc Microdissection of the gene expression codes driving nephrogenesis
    S Steven Potter
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, OH, USA
    Organogenesis 6:263-9. 2010
  4. pmc Defining the molecular character of the developing and adult kidney podocyte
    Eric W Brunskill
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati School of Medicine, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e24640. 2011
  5. doi request reprint Defining the genetic blueprint of kidney development
    S Steven Potter
    Division of Developmental Biology, Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Pediatr Nephrol 26:1469-78. 2011
  6. pmc Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy
    Eric W Brunskill
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    BMC Nephrol 13:70. 2012
  7. doi request reprint Laser capture
    S Steven Potter
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, OH, USA
    Methods Mol Biol 886:211-21. 2012
  8. pmc Gene expression programs of mouse endothelial cells in kidney development and disease
    Eric W Brunskill
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 5:e12034. 2010
  9. ncbi request reprint A gene expression atlas of early craniofacial development
    Eric W Brunskill
    Cincinnati Children s Medical Center, Division of Developmental Biology, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Biol 391:133-46. 2014
  10. pmc SP8 regulates signaling centers during craniofacial development
    Abigail D Kasberg
    Division of Developmental Biology, Cincinnati Children s Medical Center, Cincinnati, OH 45229, USA
    Dev Biol 381:312-23. 2013

Collaborators

Detail Information

Publications12

  1. pmc RNA-Seq defines novel genes, RNA processing patterns and enhancer maps for the early stages of nephrogenesis: Hox supergenes
    Eric W Brunskill
    Children s Hospital Medical Center, Division of Developmental Biology, 3333 Burnet Ave Cincinnati, OH 452239, USA
    Dev Biol 368:4-17. 2012
    ..Further, the RNA-Seq data defined hundreds of novel splice patterns and large numbers of new genes. Particularly striking was the extensive sense/antisense transcription and changing RNA processing complexities of the Hox clusters...
  2. pmc Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production
    Eric W Brunskill
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center and the University of Cincinnati School of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    BMC Dev Biol 11:15. 2011
    ..This strategy allowed us to define the changing gene expression states following induction and the onset of differentiation after birth...
  3. pmc Microdissection of the gene expression codes driving nephrogenesis
    S Steven Potter
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, OH, USA
    Organogenesis 6:263-9. 2010
    ....
  4. pmc Defining the molecular character of the developing and adult kidney podocyte
    Eric W Brunskill
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati School of Medicine, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e24640. 2011
    ..The podocytes are a subject of keen interest because of their key roles in kidney development and disease...
  5. doi request reprint Defining the genetic blueprint of kidney development
    S Steven Potter
    Division of Developmental Biology, Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Pediatr Nephrol 26:1469-78. 2011
    ..Advancing technologies are even allowing robust gene expression profiling of single cells. The final goal is the production of an exquisitely detailed atlas of the gene expression program that drives kidney development...
  6. pmc Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy
    Eric W Brunskill
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    BMC Nephrol 13:70. 2012
    ..The purpose of the study is to better define the unique character of normal mesangial cells, and to characterize their pathogenic and protective responses during diabetic nephropathy...
  7. doi request reprint Laser capture
    S Steven Potter
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, OH, USA
    Methods Mol Biol 886:211-21. 2012
    ..Notes describe the fine points of each operation, which can often mean the difference between success and failure...
  8. pmc Gene expression programs of mouse endothelial cells in kidney development and disease
    Eric W Brunskill
    Division of Developmental Biology, Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 5:e12034. 2010
    ..These studies provide a rich resource to facilitate further investigations of endothelial cell functions in kidney development, adult compartments, and disease...
  9. ncbi request reprint A gene expression atlas of early craniofacial development
    Eric W Brunskill
    Cincinnati Children s Medical Center, Division of Developmental Biology, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Biol 391:133-46. 2014
    ....
  10. pmc SP8 regulates signaling centers during craniofacial development
    Abigail D Kasberg
    Division of Developmental Biology, Cincinnati Children s Medical Center, Cincinnati, OH 45229, USA
    Dev Biol 381:312-23. 2013
    ..These results show that Sp8 primarily functions to promote Fgf expression in the ANR and OP signaling centers that drive the survival, proliferation, and differentiation of the NC and paraxial mesoderm that make the face. ..
  11. pmc Atlas of gene expression in the developing kidney at microanatomic resolution
    Eric W Brunskill
    Division of Developmental Biology, Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Cell 15:781-91. 2008
    ..In addition, the results provide deeper insight into the genetic regulatory mechanisms of kidney development...
  12. doi request reprint Building an atlas of gene expression driving kidney development: pushing the limits of resolution
    S Steven Potter
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA
    Pediatr Nephrol 29:581-8. 2014
    ..Results can identify novel types of cells and define interesting heterogeneities present within cell populations. ..