Hermine Brunner

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. doi request reprint Pediatric SLE--towards a comprehensive management plan
    Hermine I Brunner
    William S Rowe Division of Rheumatology and Lupus Center, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Nat Rev Rheumatol 7:225-33. 2011
  2. pmc Validation of the Pediatric Automated Neuropsychological Assessment Metrics in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, E 4010, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Arthritis Care Res (Hoboken) 65:372-81. 2013
  3. pmc Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritis
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Arthritis Rheum 64:2687-97. 2012
  4. pmc Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis
    Lindsey E Romick-Rosendale
    Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA
    Arthritis Res Ther 13:R199. 2011
  5. doi request reprint Developing outcome measures for paediatric rheumatic diseases
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, Cincinnati, OH 45229 3039, USA
    Best Pract Res Clin Rheumatol 23:609-24. 2009
  6. ncbi request reprint Differences in disease outcomes between medicaid and privately insured children: possible health disparities in juvenile rheumatoid arthritis
    Hermine I Brunner
    William Rowe Division of Rheumatology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Arthritis Rheum 55:378-84. 2006
  7. ncbi request reprint Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Rheum 54:2577-84. 2006
  8. ncbi request reprint Initial validation of the Pediatric Automated Neuropsychological Assessment Metrics for childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Rheum 57:1174-82. 2007
  9. ncbi request reprint Corticosteroid use in childhood-onset systemic lupus erythematosus-practice patterns at four pediatric rheumatology centers
    H I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, USA
    Clin Exp Rheumatol 27:155-62. 2009
  10. doi request reprint Health-related quality of life and its relationship to patient disease course in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Rheumatol 36:1536-45. 2009

Research Grants

  1. TRIPTORELIN FOR OVARY PROTECTION IN CHILDHOOD LIPUS
    Hermine Brunner; Fiscal Year: 2007

Collaborators

Detail Information

Publications44

  1. doi request reprint Pediatric SLE--towards a comprehensive management plan
    Hermine I Brunner
    William S Rowe Division of Rheumatology and Lupus Center, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Nat Rev Rheumatol 7:225-33. 2011
    ....
  2. pmc Validation of the Pediatric Automated Neuropsychological Assessment Metrics in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, E 4010, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Arthritis Care Res (Hoboken) 65:372-81. 2013
    ..To evaluate the reproducibility and validity of the Pediatric Automated Neuropsychological Assessment Metrics (Ped-ANAM) when used in childhood-onset systemic lupus erythematosus (cSLE)...
  3. pmc Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritis
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Arthritis Rheum 64:2687-97. 2012
    ....
  4. pmc Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis
    Lindsey E Romick-Rosendale
    Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA
    Arthritis Res Ther 13:R199. 2011
    ....
  5. doi request reprint Developing outcome measures for paediatric rheumatic diseases
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, Cincinnati, OH 45229 3039, USA
    Best Pract Res Clin Rheumatol 23:609-24. 2009
    ....
  6. ncbi request reprint Differences in disease outcomes between medicaid and privately insured children: possible health disparities in juvenile rheumatoid arthritis
    Hermine I Brunner
    William Rowe Division of Rheumatology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Arthritis Rheum 55:378-84. 2006
    ..To determine the relationship between health insurance status and disease outcome in children with juvenile rheumatoid arthritis (JRA)...
  7. ncbi request reprint Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Rheum 54:2577-84. 2006
    ..We undertook this study to determine the relationship between urinary NGAL excretion and SLE disease activity or damage, with a focus on nephritis...
  8. ncbi request reprint Initial validation of the Pediatric Automated Neuropsychological Assessment Metrics for childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Rheum 57:1174-82. 2007
    ..To evaluate the concurrent validity and diagnostic accuracy of the pediatric Automated Neuropsychological Assessment Metrics (Ped-ANAM) when used in childhood-onset systemic lupus erythematosus (SLE)...
  9. ncbi request reprint Corticosteroid use in childhood-onset systemic lupus erythematosus-practice patterns at four pediatric rheumatology centers
    H I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, USA
    Clin Exp Rheumatol 27:155-62. 2009
    ..To evaluate corticosteroid prescribing patterns in childhood-onset systemic lupus erythematosus (SLE), comparing four academic pediatric rheumatology practices...
  10. doi request reprint Health-related quality of life and its relationship to patient disease course in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Rheumatol 36:1536-45. 2009
    ....
  11. pmc Prospective validation of the provisional criteria for the evaluation of response to therapy in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, E 4010, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Arthritis Care Res (Hoboken) 62:335-44. 2010
    ..To prospectively validate the provisional criteria for the evaluation of response to therapy in children with systemic lupus erythematosus (SLE)...
  12. pmc Toward the development of criteria for global flares in juvenile systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Care Res (Hoboken) 62:811-20. 2010
    ..To develop a definition of global flare in juvenile systemic lupus erythematosus (SLE) and derive candidate criteria for measuring juvenile SLE flares...
  13. pmc Minimal clinically important differences of disease activity indices in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Care Res (Hoboken) 62:950-9. 2010
    ..To determine the minimal clinically important differences (MCIDs) of validated measures of systemic lupus erythematosus (SLE) disease activity in childhood-onset SLE...
  14. pmc Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, Ohio, USA
    Arthritis Care Res (Hoboken) 63:1213-23. 2011
    ..To develop widely acceptable preliminary criteria of global flare for childhood-onset systemic lupus erythematosus (cSLE)...
  15. ncbi request reprint Disease outcomes and ovarian function of childhood-onset systemic lupus erythematosus
    H I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, OH 45229, USA
    Lupus 15:198-206. 2006
    ..8; 95% CI: 1.7-4.8; P = 0.026). Patient mortality and disease damage with cSLE continue to be high. Although overt POF with cyclophosphamide exposure is rare, it is a risk factor for significantly decreased ovarian reserve cSLE...
  16. ncbi request reprint Cost of treatment of childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, William Rowe Division of Rheumatology E 4010, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Arthritis Rheum 55:184-8. 2006
    ..To determine the direct cost of care of children with childhood-onset systemic lupus erythematosus (cSLE), and to determine the direct cost per quality-adjusted life year (QALY) with cSLE...
  17. ncbi request reprint European Consensus Lupus Activity Measurement is sensitive to change in disease activity in childhood-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio, USA
    Arthritis Rheum 49:335-41. 2003
    ..To confirm the construct validity and to characterize the measurement properties of the ECLAM by assessing its ability to predict damage and steroid requirements...
  18. ncbi request reprint Lupus headaches in childhood-onset systemic lupus erythematosus: relationship to disease activity as measured by the systemic lupus erythematosus disease activity index (SLEDAI) and disease damage
    H I Brunner
    William Rowe Division of Rheumatology, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati 45229 3039, USA
    Lupus 12:600-6. 2003
    ..When used in children, the insensitivity of the SLEDAI to capture LHA did not seem to decrease the responsiveness of the SLEDAI to detect clinically important worsening of disease, or negatively impact on its ability to predict damage...
  19. ncbi request reprint Health-related quality of life in children with rheumatic diseases
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, OH 45229 3039, USA
    Curr Opin Rheumatol 15:602-12. 2003
    ..For the interpretation of the values of the physical function and health-related quality of life measures, their measurement properties have to be studied...
  20. ncbi request reprint Health of children with chronic arthritis: relationship of different measures and the quality of parent proxy reporting
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Arthritis Rheum 51:763-73. 2004
    ..To evaluate whether HRQOL scores vary as a function of disability status beyond chance. To assess the quality of the parent proxy report for HRQOL as compared with disability, pain, and well-being...
  21. ncbi request reprint Minimal clinically important differences of the childhood health assessment questionnaire
    Hermine I Brunner
    Division of Rheumatology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Rheumatol 32:150-61. 2005
    ..125. We estimated minimal clinically important differences (MCID) of the CHAQ for worsening and improvement that were actually experienced by children with JRA using patient, parent, and clinical perspectives...
  22. ncbi request reprint Gastrointestinal symptoms and their association with health-related quality of life of children with juvenile rheumatoid arthritis: validation of a gastrointestinal symptom questionnaire
    Hermine I Brunner
    Division of Rheumatology E 4010, Cincinnati Children s Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    J Clin Rheumatol 11:194-204. 2005
    ....
  23. pmc Neutrophil gelatinase-associated lipocalin is a predictor of the course of global and renal childhood-onset systemic lupus erythematosus disease activity
    Claas H Hinze
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Arthritis Rheum 60:2772-81. 2009
    ..To determine whether neutrophil gelatinase-associated lipocalin (NGAL) can predict worsening of global and renal disease activity in childhood-onset systemic lupus erythematosus (SLE)...
  24. pmc Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis
    Michiko Suzuki
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Pediatr Res 65:530-6. 2009
    ..0001), and L-PGDS (p < 0.01) occurred, indicating that these PS proteins are biomarkers of LN activity and may help anticipate the future course of LN...
  25. doi request reprint Disease control and health-related quality of life in juvenile idiopathic arthritis
    Michael Seid
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Arthritis Rheum 61:393-9. 2009
    ....
  26. ncbi request reprint Specialized neuromuscular training to improve neuromuscular function and biomechanics in a patient with quiescent juvenile rheumatoid arthritis
    Gregory D Myer
    Sports Medicine Biodynamics Center and Human Performance Laboratory, Cincinnati Children s Hospital Medical Center, MLC 10001, Cincinnati, OH 45229, USA
    Phys Ther 85:791-802. 2005
    ..The purpose of this case report is to describe a novel multidisciplinary approach for evaluating and preparing a patient with quiescent juvenile rheumatoid arthritis (JRA) for safe sports participation...
  27. doi request reprint Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
    Arthritis Rheum 58:556-62. 2008
    ..To investigate potential differences between childhood-onset and adult-onset systemic lupus erythematosus (SLE)...
  28. ncbi request reprint Risk factors for damage in childhood-onset systemic lupus erythematosus: cumulative disease activity and medication use predict disease damage
    Hermine I Brunner
    Division of Rheumatology, Children s Hospital Medical Center, University of Cincinnati, PAV2 129, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Arthritis Rheum 46:436-44. 2002
    ....
  29. ncbi request reprint Identification of a urinary proteomic signature for lupus nephritis in children
    Michiko Suzuki
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA
    Pediatr Nephrol 22:2047-57. 2007
    ..90 for 22, 23, 44, 79, and 100 kDa biomarkers. Thus, SELDI-TOF-MS has identified a urine proteomic signature strongly associated with SLE renal involvement and active SLE nephritis...
  30. doi request reprint Neutrophil gelatinase-associated lipocalin as a biomarker of disease activity in pediatric lupus nephritis
    Michiko Suzuki
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Pediatr Nephrol 23:403-12. 2008
    ..3 +/- 6.2 or 21%; renal disease activity: 20.2 +/- 6.0 or 51%; both p = not significant]. In conclusion, NGAL in urine but not in plasma represents a novel biomarker for renal disease activity in pSLE...
  31. ncbi request reprint Effectively measuring adherence to medications for systemic lupus erythematosus in a clinical setting
    Sri Koneru
    University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Arthritis Rheum 57:1000-6. 2007
    ....
  32. ncbi request reprint Preliminary definition of disease flare in juvenile rheumatoid arthritis
    Hermine I Brunner
    William S Rowe Division of Rheumatology, Cincinnati Children s Hospital Medical Center, OH 45229, USA
    J Rheumatol 29:1058-64. 2002
    ..To develop preliminary criteria for defining disease flare in patients with polyarticular-course juvenile rheumatoid arthritis (JRA)...
  33. ncbi request reprint Item weightings for the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Disease Damage Index using Rasch analysis do not lead to an important improvement
    Hermine I Brunner
    William Rowe Division of Rheumatology, Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Rheumatol 30:292-7. 2003
    ....
  34. doi request reprint Adherence to medications in systemic lupus erythematosus
    Sri Koneru
    Division of Immunology, University of Cincinnati Medical Center, Cincinnati, OH, USA
    J Clin Rheumatol 14:195-201. 2008
    ..Lack of adherence is a ubiquitous problem which can be a hindrance in the treatment of chronic conditions like systemic lupus erythematosus (SLE)...
  35. doi request reprint Monitoring methotrexate toxicity in juvenile idiopathic arthritis
    Lakshmi Kocharla
    Division of Rheumatology, University of Cincinnati Medical Center, Cincinnati, OH 45229 3039, USA
    J Rheumatol 36:2813-8. 2009
    ....
  36. pmc Pediatric lupus--are there differences in presentation, genetics, response to therapy, and damage accrual compared with adult lupus?
    Rina Mina
    Division of Rheumatology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MC 4010, Cincinnati, OH 45229, USA
    Rheum Dis Clin North Am 36:53-80, vii-viii. 2010
    ..Mortality rates remain higher with pediatric SLE. Children and adolescents accrue more damage, especially in the renal, ocular and musculoskeletal organ systems. Conversely, cardiovascular mortality is more prevalent in adults with SLE...
  37. ncbi request reprint Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study
    Mark W DiFrancesco
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Arthritis Rheum 56:4151-63. 2007
    ....
  38. ncbi request reprint Feasibility and construct validity of the parent willingness-to-pay technique for children with juvenile idiopathic arthritis
    Andrea C Barron
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229 3039, USA
    Arthritis Rheum 51:899-908. 2004
    ..To assess the feasibility and construct validity of the willingness-to-pay (WTP) technique for measuring health care preferences in families of children with juvenile idiopathic arthritis (JIA)...
  39. ncbi request reprint Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: possible link to vasculopathy
    Ndate Fall
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 52:3175-80. 2005
    ..To investigate the relationship between the vasculopathy of juvenile dermatomyositis (juvenile DM) and the balance between the angiostatic ELR- and angiogenic ELR+ CXC chemokines in the muscle of patients with the disease...
  40. pmc An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis
    Deijanira Alves De Albuquerque
    Department of Internal Medicine, University of Cincinnati College of Medicine, Veterans Administration Medical Center and Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45267 0563, USA
    Kidney Int 65:846-59. 2004
    ..Here, we examine the effects of treatment with captopril on lupus nephritis and discuss the potential mechanism(s) by which this agent exerts its renoprotective effects...
  41. ncbi request reprint The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis
    Jack Bleesing
    Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 56:965-71. 2007
    ..This study was undertaken to assess the value of serum sIL-2Ralpha and sCD163 in diagnosing acute macrophage activation syndrome complicating systemic juvenile idiopathic arthritis (JIA)...
  42. ncbi request reprint Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue
    Michael P Scola
    Department of Pediatrics, Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Rheumatol 29:369-78. 2002
    ..To compare synovial tissue cytokine mRNA expression between patients with juvenile rheumatoid arthritis (JRA) and a heterogeneous group of non-autoimmune arthropathies (controls) with respect to type 1/type 2 balance...
  43. doi request reprint Pediatric rheumatology--its own specialty
    Claas Hinze
    Nat Clin Pract Rheumatol 4:279. 2008
  44. ncbi request reprint Targeting B cells in the treatment of childhood-onset systemic lupus erythematosus
    Jennifer L Huggins
    J Pediatr 148:571-3. 2006

Research Grants3

  1. TRIPTORELIN FOR OVARY PROTECTION IN CHILDHOOD LIPUS
    Hermine Brunner; Fiscal Year: 2007
    ..Abstract Not Provided ..