Research Topics
Species | Tesfaye M BayeSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Population structure analysis using rare and common functional variantsTesfaye M Baye
Division of Asthma Research, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
BMC Proc 5:S8. 2011....- Inter-chromosomal variation in the pattern of human population genetic structureTesfaye M Baye
Cincinnati Children s Hospital Medical Center, Division of Asthma Research, Department of Pediatrics, University of Cincinnati, OH 45229, USA
Hum Genomics 5:220-40. 2011.... - Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthmaLisa J Martin
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America
PLoS ONE 7:e33454. 2012..Associations between two genes in the autophagy pathway, ATG5 and ATG7, with childhood asthma were investigated... - Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differencesMelinda Butsch Kovacic
Division of Asthma Research, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
PLoS ONE 6:e23714. 2011..Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes... - Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approachLili Ding
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
BMC Proc 5:S10. 2011..We conclude that our method provides a novel and broadly applicable strategy for obtaining association results with a reasonably low proportion of false discovery and that it can be routinely used in resequencing studies... - Effect of population stratification analysis on false-positive rates for common and rare variantsHua He
Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
BMC Proc 5:S116. 2011..Taken together, these results suggest that sequence-level data should be interpreted with caution, because extremely rare SNPs may exhibit sporadic association that is not controlled using PCA... - Family- and population-based designs identify different rare causal variantsXue Zhang
Divisions of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
BMC Proc 5:S36. 2011..Family-based and population-based study designs can be complementary in the identification of rare causal variants and should be considered in future studies... - Comparison of measures of marker informativeness for ancestry and admixture mappingLili Ding
Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
BMC Genomics 12:622. 2011.... - Differences in candidate gene association between European ancestry and African American asthmatic childrenTesfaye M Baye
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America
PLoS ONE 6:e16522. 2011..Our aim was to compare association patterns of asthma candidate genes between children of European and African ancestry... - Application of genetic/genomic approaches to allergic disordersTesfaye M Baye
Division of Asthma Research, University of Cincinnati, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Allergy Clin Immunol 126:425-36; quiz 437-8. 2010..We will discuss genetic and phenotypic variation, statistical approaches for gene discovery, public databases, functional genomics, clinical implications, and the challenges that remain...