Tesfaye M Baye

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations
    Lili Ding
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA
    Hum Genomics 7:16. 2013
  2. pmc Population structure analysis using rare and common functional variants
    Tesfaye M Baye
    Division of Asthma Research, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    BMC Proc 5:S8. 2011
  3. pmc Inter-chromosomal variation in the pattern of human population genetic structure
    Tesfaye M Baye
    Cincinnati Children s Hospital Medical Center, Division of Asthma Research, Department of Pediatrics, University of Cincinnati, OH 45229, USA
    Hum Genomics 5:220-40. 2011
  4. pmc Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma
    Lisa J Martin
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America
    PLoS ONE 7:e33454. 2012
  5. pmc Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences
    Melinda Butsch Kovacic
    Division of Asthma Research, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e23714. 2011
  6. pmc Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approach
    Lili Ding
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    BMC Proc 5:S10. 2011
  7. pmc Effect of population stratification analysis on false-positive rates for common and rare variants
    Hua He
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    BMC Proc 5:S116. 2011
  8. pmc Family- and population-based designs identify different rare causal variants
    Xue Zhang
    Divisions of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    BMC Proc 5:S36. 2011
  9. pmc Comparison of measures of marker informativeness for ancestry and admixture mapping
    Lili Ding
    Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
    BMC Genomics 12:622. 2011
  10. pmc AncestrySNPminer: a bioinformatics tool to retrieve and develop ancestry informative SNP panels
    Sushil Amirisetty
    Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH 45229, USA
    Genomics 100:57-63. 2012

Detail Information

Publications12

  1. pmc Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations
    Lili Ding
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA
    Hum Genomics 7:16. 2013
    ..We performed genome-wide association studies on 859,790 SNPs genotyped in 527 affected offspring trios of European, African, and Hispanic ancestry using publically available asthma database in the Genotypes and Phenotypes database...
  2. pmc Population structure analysis using rare and common functional variants
    Tesfaye M Baye
    Division of Asthma Research, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    BMC Proc 5:S8. 2011
    ....
  3. pmc Inter-chromosomal variation in the pattern of human population genetic structure
    Tesfaye M Baye
    Cincinnati Children s Hospital Medical Center, Division of Asthma Research, Department of Pediatrics, University of Cincinnati, OH 45229, USA
    Hum Genomics 5:220-40. 2011
    ....
  4. pmc Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma
    Lisa J Martin
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America
    PLoS ONE 7:e33454. 2012
    ..Associations between two genes in the autophagy pathway, ATG5 and ATG7, with childhood asthma were investigated...
  5. pmc Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences
    Melinda Butsch Kovacic
    Division of Asthma Research, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e23714. 2011
    ..Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes...
  6. pmc Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approach
    Lili Ding
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    BMC Proc 5:S10. 2011
    ..We conclude that our method provides a novel and broadly applicable strategy for obtaining association results with a reasonably low proportion of false discovery and that it can be routinely used in resequencing studies...
  7. pmc Effect of population stratification analysis on false-positive rates for common and rare variants
    Hua He
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    BMC Proc 5:S116. 2011
    ..Taken together, these results suggest that sequence-level data should be interpreted with caution, because extremely rare SNPs may exhibit sporadic association that is not controlled using PCA...
  8. pmc Family- and population-based designs identify different rare causal variants
    Xue Zhang
    Divisions of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    BMC Proc 5:S36. 2011
    ..Family-based and population-based study designs can be complementary in the identification of rare causal variants and should be considered in future studies...
  9. pmc Comparison of measures of marker informativeness for ancestry and admixture mapping
    Lili Ding
    Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
    BMC Genomics 12:622. 2011
    ....
  10. pmc AncestrySNPminer: a bioinformatics tool to retrieve and develop ancestry informative SNP panels
    Sushil Amirisetty
    Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH 45229, USA
    Genomics 100:57-63. 2012
    ..AncestrySNPminer can be freely accessed at https://research.cchmc.org/mershalab/AncestrySNPminer/login.php...
  11. pmc Differences in candidate gene association between European ancestry and African American asthmatic children
    Tesfaye M Baye
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e16522. 2011
    ..Our aim was to compare association patterns of asthma candidate genes between children of European and African ancestry...
  12. pmc Application of genetic/genomic approaches to allergic disorders
    Tesfaye M Baye
    Division of Asthma Research, University of Cincinnati, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Allergy Clin Immunol 126:425-36; quiz 437-8. 2010
    ..We will discuss genetic and phenotypic variation, statistical approaches for gene discovery, public databases, functional genomics, clinical implications, and the challenges that remain...