Research Topics
Species | Rajit K BasuSummaryAffiliation: Cincinnati Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Renal angina: an emerging paradigm to identify children at risk for acute kidney injuryRajit K Basu
Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Pediatr Nephrol 27:1067-78. 2012..Fulfillment of renal angina criteria will improve the efficiency of AKI prediction by biomarkers, in turn expediting early therapy and assisting in creation of AKI-predictive scoring systems...
An update and review of acute kidney injury in pediatricsRajit K Basu
Division of Critical Care, Department of Pediatrics, Cincinnati Children s Hospital and Medical Center, University of Cincinnati, Cincinnati, OH, USA
Pediatr Crit Care Med 12:339-47. 2011..To inform the pediatric intensivist of recent advancements in acute kidney injury diagnosis and management...
Antecedent acute kidney injury worsens subsequent endotoxin-induced lung inflammation in a two-hit mouse modelRajit K Basu
Divisions of Critical Care, Cincinnati Children s Hospital and Medical Center, Ohio, USA
Am J Physiol Renal Physiol 301:F597-604. 2011..The model holds clinical relevance for patients at risk of lung injury after ischemic injury to the kidney...
Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarrayRajit K Basu
Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45223, USA
Crit Care 15:R273. 2011..The objective of our study was to determine whether microarray data from children with septic shock could be used to derive a panel of candidate biomarkers for predicting SSAKI...
Validation of a gene expression-based subclassification strategy for pediatric septic shockHector R Wong
Department of Pediatrics, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Crit Care Med 39:2511-7. 2011..Here we attempted to prospectively validate the existence of these gene expression-based subclasses in a validation cohort...
Pediatric sepsis: preparing for the future against a global scourgeCarley Riley
Division of Critical Care Medicine, Cincinnati Children s Hospital and Medical Center, 3333 Burnet Avenue, Division of Critical Care, ML 2005, Cincinnati, OH, 45229, USA
Curr Infect Dis Rep 14:503-11. 2012..Finally, we discuss the future of pediatric sepsis. We focus on approaches that carry the most substantive impact on the global burden of disease...
Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of conceptHector R Wong
Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Crit Care Med 38:1955-61. 2010..To develop a clinically feasible stratification strategy for pediatric septic shock, using gene expression mosaics and a 100-gene signature representing the first 24 hrs of admission to the pediatric intensive care unit...
Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expressionRajit K Basu
Divisions of Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Am J Physiol Renal Physiol 300:F898-905. 2011..Taken together, our data demonstrate cooperation in signaling between Smad3 and HIF-1α and suggest a new paradigm in which HIF-1α is necessary for normoxic, TGF-β1-stimulated renal cell fibrogenesis...
Acute renal replacement therapy in pediatricsRajit K Basu
Division of Critical Care and Center for Acute Care Nephrology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Int J Nephrol 2011:785392. 2011..As no standard of care is in widespread use for RRT in AKI or in multiorgan disease, we conclude in this paper that prospective studies of RRT are needed to identify best practice guidelines...
