Delong Liu

Summary

Affiliation: CIIT Centers for Health Research
Country: USA

Publications

  1. ncbi Phase analysis of circadian-related genes in two tissues
    Delong Liu
    Biostatistics Branch, National Institute of Environmental Health Sciences, MD A3 03, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
    BMC Bioinformatics 7:87. 2006
  2. ncbi Analysis of variation of amplitudes in cell cycle gene expression
    Delong Liu
    CIIT Ceters for Health Research, 6 Davis Drive, Research Triangle Park, NC 27709, USA
    Theor Biol Med Model 2:46. 2005
  3. ncbi Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone
    Kevin W Gaido
    The Hamner Institutes for Health Sciences Centers for Health Research, Research Triangle Park, NC 27709, USA
    Toxicol Sci 97:491-503. 2007
  4. ncbi A geometric approach to determine association and coherence of the activation times of cell-cycling genes under differing experimental conditions
    Delong Liu
    Biostatistics Branch, MD:A3-03, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, NC 27709, USA
    Bioinformatics 20:2521-8. 2004
  5. ncbi A random-periods model for expression of cell-cycle genes
    Delong Liu
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, P.O. Box 12233, Research Triangle Park, NC 27709, USA
    Proc Natl Acad Sci U S A 101:7240-5. 2004
  6. ncbi Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages
    Stephanie A Lahousse
    Division of Biological Sciences, CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 93:369-81. 2006
  7. ncbi p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis
    Yan Xiong
    Endocrine Biology Program, Center for Integrated Genomics, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Biol Chem 282:4975-82. 2007
  8. ncbi Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest
    Jen Wei Chiao
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Carcinogenesis 25:1403-8. 2004
  9. ncbi Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells
    Xudong Ma
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Int J Oncol 28:1287-93. 2006
  10. ncbi The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo
    Lulu Lu
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Oncol Rep 16:1363-7. 2006

Collaborators

Detail Information

Publications11

  1. ncbi Phase analysis of circadian-related genes in two tissues
    Delong Liu
    Biostatistics Branch, National Institute of Environmental Health Sciences, MD A3 03, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
    BMC Bioinformatics 7:87. 2006
    ..These interesting biological observations prompt a statistical question regarding how to distinguish the synchronized genes from genes that are systematically lagged in phase/peak expression time across two tissues...
  2. ncbi Analysis of variation of amplitudes in cell cycle gene expression
    Delong Liu
    CIIT Ceters for Health Research, 6 Davis Drive, Research Triangle Park, NC 27709, USA
    Theor Biol Med Model 2:46. 2005
    ..We investigated whether different cell-arresting methods have impacts on the maximum expression levels (amplitudes) of a cell cycle related gene...
  3. ncbi Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone
    Kevin W Gaido
    The Hamner Institutes for Health Sciences Centers for Health Research, Research Triangle Park, NC 27709, USA
    Toxicol Sci 97:491-503. 2007
    ..This response in the mouse occurs without a measurable decrease in testicular testosterone, suggesting that altered seminiferous cord formation and gonocyte multinucleation may not be mechanistically linked to lowered testosterone...
  4. ncbi A geometric approach to determine association and coherence of the activation times of cell-cycling genes under differing experimental conditions
    Delong Liu
    Biostatistics Branch, MD:A3-03, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, NC 27709, USA
    Bioinformatics 20:2521-8. 2004
    ..Our proposed methodology is illustrated by applying it to a HeLa cell-cycle gene-expression data...
  5. ncbi A random-periods model for expression of cell-cycle genes
    Delong Liu
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, P.O. Box 12233, Research Triangle Park, NC 27709, USA
    Proc Natl Acad Sci U S A 101:7240-5. 2004
    ..The model permits estimation of and hypothesis testing about biologically meaningful parameters that characterize cycling genes...
  6. ncbi Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages
    Stephanie A Lahousse
    Division of Biological Sciences, CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 93:369-81. 2006
    ..These data demonstrate that similar genetic targets are altered following fetal and prepubertal phthalate exposure, suggesting that the initial mechanism of fetal and prepubertal phthalate-induced testicular injury is shared...
  7. ncbi p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis
    Yan Xiong
    Endocrine Biology Program, Center for Integrated Genomics, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Biol Chem 282:4975-82. 2007
    ..Together, we have identified an inhibitory role for p38 in the transcription of central lipogenic genes, SREBPs, and PGC-1beta and hepatic lipogenesis...
  8. ncbi Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest
    Jen Wei Chiao
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Carcinogenesis 25:1403-8. 2004
    ..PEITC-NAC may prevent initiation of carcinogenesis and modulate the post-initiation phase by targeting cell cycle regulators and apoptosis induction...
  9. ncbi Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells
    Xudong Ma
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Int J Oncol 28:1287-93. 2006
    ..The results revealed a potential selective effect of isothiocyanates to inhibit the growth of malignant cells...
  10. ncbi The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo
    Lulu Lu
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Oncol Rep 16:1363-7. 2006
    ..In conclusion, PHI induced apoptosis and inhibited the growth of xenografts by targeting the cell cycle regulators. PHI induced selective apoptosis effects in the rapidly growing tumor cells but not in the normal tissues...
  11. ncbi Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention
    Longgui Wang
    Division of Medical Oncology, Mount Sinai Medical Center, New York, NY 10029, USA
    Int J Oncol 24:187-92. 2004
    ..The potential of SFN, as an active dietary factor to inhibit initiation and post-initiation of prostate cancer carcinogenesis is discussed...