W S Weintraub

Summary

Affiliation: Christiana Care Health System
Country: USA

Publications

  1. ncbi request reprint Comparative effectiveness of revascularization strategies
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 366:1467-76. 2012
  2. pmc Prediction of long-term mortality after percutaneous coronary intervention in older adults: results from the National Cardiovascular Data Registry
    William S Weintraub
    Christiana Care Health System, 4755 Ogletown Stanton Road, Newark, DE 19718, USA
    Circulation 125:1501-10. 2012
  3. ncbi request reprint Cutting through the statistical fog: understanding and evaluating non-inferiority trials
    W S Weintraub
    John H Ammon Chair, Thomas Jefferson University, Philadelphia, PA, USA
    Int J Clin Pract 64:1359-66. 2010
  4. doi request reprint Pharmacoeconomic concepts in antiplatelet therapy: understanding cost-effectiveness analyses using clopidogrel as an example
    William S Weintraub
    Christiana Care Health System, Center for Heart and Vascular Health, Newark, Delaware 19718, USA
    J Cardiovasc Pharmacol Ther 13:107-19. 2008
  5. ncbi request reprint Effect of PCI on quality of life in patients with stable coronary disease
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 359:677-87. 2008
  6. ncbi request reprint Economics methods in the Clinical Outcomes Utilizing percutaneous coronary Revascularization and Aggressive Guideline-driven drug Evaluation (COURAGE) trial
    William S Weintraub
    Atlanta VA Medical Center, Decatur, GA, USA
    Am Heart J 151:1180-5. 2006
  7. doi request reprint Cost-effectiveness of percutaneous coronary intervention in optimally treated stable coronary patients
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    Circ Cardiovasc Qual Outcomes 1:12-20. 2008
  8. doi request reprint Is an invasive interventional strategy of value in non-ST-elevation acute coronary syndromes?
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    Nat Clin Pract Cardiovasc Med 5:754-5. 2008
  9. ncbi request reprint The pathophysiology and burden of restenosis
    William S Weintraub
    Department of Cardiology and Christiana Center for Outcomes Research, Christiana Care Health Services, Newark, Delaware 19718, USA
    Am J Cardiol 100:3K-9K. 2007
  10. ncbi request reprint Outcomes and long-term survival for patients undergoing mitral valve repair versus replacement: effect of age and concomitant coronary artery bypass grafting
    Vinod H Thourani
    Joseph B Whitehead Department of Surgery, Division of Cardiothoracic Surgery, Carlyle Fraser Heart Center, Atlanta, GA, USA
    Circulation 108:298-304. 2003

Research Grants

  1. EXERCISE AND CARDIOVASCULAR DISEASE
    William Weintraub; Fiscal Year: 2003

Collaborators

Detail Information

Publications84

  1. ncbi request reprint Comparative effectiveness of revascularization strategies
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 366:1467-76. 2012
    ..The American College of Cardiology Foundation (ACCF) and the Society of Thoracic Surgeons (STS) collaborated to compare the rates of long-term survival after PCI and CABG...
  2. pmc Prediction of long-term mortality after percutaneous coronary intervention in older adults: results from the National Cardiovascular Data Registry
    William S Weintraub
    Christiana Care Health System, 4755 Ogletown Stanton Road, Newark, DE 19718, USA
    Circulation 125:1501-10. 2012
    ..The purpose of this study was to develop a long-term model to predict mortality after percutaneous coronary intervention in both patients with ST-segment elevation myocardial infarction and those with more stable coronary disease...
  3. ncbi request reprint Cutting through the statistical fog: understanding and evaluating non-inferiority trials
    W S Weintraub
    John H Ammon Chair, Thomas Jefferson University, Philadelphia, PA, USA
    Int J Clin Pract 64:1359-66. 2010
    ..Objectives and primary end-points must be clearly stated and rigorous standards met for sample size, establishing the margin, patient characteristics and adherence to protocol...
  4. doi request reprint Pharmacoeconomic concepts in antiplatelet therapy: understanding cost-effectiveness analyses using clopidogrel as an example
    William S Weintraub
    Christiana Care Health System, Center for Heart and Vascular Health, Newark, Delaware 19718, USA
    J Cardiovasc Pharmacol Ther 13:107-19. 2008
    ..Greater clinician understanding of pharmacoeconomic principles (and pitfalls) will enhance input of the physicians into the decision-making process to maximize the benefit of limited health care resources...
  5. ncbi request reprint Effect of PCI on quality of life in patients with stable coronary disease
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 359:677-87. 2008
    ..It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease...
  6. ncbi request reprint Economics methods in the Clinical Outcomes Utilizing percutaneous coronary Revascularization and Aggressive Guideline-driven drug Evaluation (COURAGE) trial
    William S Weintraub
    Atlanta VA Medical Center, Decatur, GA, USA
    Am Heart J 151:1180-5. 2006
    ..A multilevel regression model will assess cost-effectiveness from a net benefit perspective. These approaches should provide the most detailed assessment available of the cost-effectiveness of PCI for coronary artery disease...
  7. doi request reprint Cost-effectiveness of percutaneous coronary intervention in optimally treated stable coronary patients
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    Circ Cardiovasc Qual Outcomes 1:12-20. 2008
    ..After 4.6 years, there was no difference in the primary end point of death or myocardial infarction, although PCI improved quality of life. The present study evaluated the relative cost and cost-effectiveness of PCI in the COURAGE trial...
  8. doi request reprint Is an invasive interventional strategy of value in non-ST-elevation acute coronary syndromes?
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    Nat Clin Pract Cardiovasc Med 5:754-5. 2008
    ..Although available data are not based on the latest technology, another trial in this area would be difficult to conduct and of questionable ethics...
  9. ncbi request reprint The pathophysiology and burden of restenosis
    William S Weintraub
    Department of Cardiology and Christiana Center for Outcomes Research, Christiana Care Health Services, Newark, Delaware 19718, USA
    Am J Cardiol 100:3K-9K. 2007
    ..Recent studies suggest that the pharmacologic management of restenosis is now feasible. Together, the judicious use of stents and oral pharmacotherapy promise to reduce the risk for restenosis, even among high-risk patients...
  10. ncbi request reprint Outcomes and long-term survival for patients undergoing mitral valve repair versus replacement: effect of age and concomitant coronary artery bypass grafting
    Vinod H Thourani
    Joseph B Whitehead Department of Surgery, Division of Cardiothoracic Surgery, Carlyle Fraser Heart Center, Atlanta, GA, USA
    Circulation 108:298-304. 2003
    ..A paucity of literature is available on the effects of age and coronary artery bypass grafting (CABG) on the outcomes of patients undergoing mitral valve (MV) repair versus replacement...
  11. ncbi request reprint Effect of cardiac surgery patient characteristics on patient outcomes from 1981 through 1995
    C D Warner
    Emory Healthcare, Atlanta, GA, USA
    Circulation 96:1575-9. 1997
    ....
  12. ncbi request reprint Improving cost and outcome of coronary surgery
    W S Weintraub
    Division of Cardiology, School of Medicine, Health Policy and Management, Emory University, Atlanta, GA, USA
    Circulation 98:II23-8. 1998
    ..There has been increasing interest in improving the outcome of coronary surgery while also seeking to minimize cost. It was the purpose of the present study to determine changes in the outcome and cost of CABG between 1988 and 1996...
  13. ncbi request reprint Invited commentary
    William S Weintraub
    Christiana Care Health Services, 4755 Ogletown Stanton Rd, Newark, DE19718
    Ann Thorac Surg 82:810-1. 2006
  14. pmc Cost-effectiveness of clopidogrel in acute coronary syndromes in Canada: a long-term analysis based on the CURE trial
    Paul Kolm
    Christiana Care Health System, Newark, Delaware, USA
    Can J Cardiol 23:1037-42. 2007
    ....
  15. ncbi request reprint Coronary stent restenosis in patients treated with cilostazol
    John S Douglas
    Emory University School of Medicine, Atlanta, GA, USA
    Circulation 112:2826-32. 2005
    ..We undertook a randomized, double-blind, placebo-controlled trial to determine whether cilostazol, a drug that suppresses intimal proliferation, would reduce renarrowing in patients after stent implantation in native coronary arteries...
  16. doi request reprint The risk of cardiovascular events in primary care patients following an episode of severe hypertension
    Edward Ewen
    Christiana Care Health System, Center for Outcomes Research, Newark, DE 19713, USA
    J Clin Hypertens (Greenwich) 11:175-82. 2009
    ..1 in the mild group, 15.1 in the moderate group, and 25.0 in the severe group. An episode of severe BP elevation is common in primary care practice and is associated with substantial excess cardiovascular morbidity...
  17. ncbi request reprint Determining the in-hospital cost of bleeding in patients undergoing percutaneous coronary intervention
    Edward F Ewen
    Christiana Care Health System, Center for Outcomes Research, Newark, Delaware 19713, USA
    J Interv Cardiol 22:266-73. 2009
    ..This retrospective analysis examines and contrasts the in-hospital cost of bleeding associated with this procedure using six bleeding definitions employed in recent clinical trials...
  18. ncbi request reprint Comparison of recovery after mitral valve repair and replacement
    Liping Zhao
    Christiana Care Health System, Newark, Del 19713, USA
    J Thorac Cardiovasc Surg 133:1257-63. 2007
    ..We sought to examine the comparative improvement in health status after primary mitral valve repair versus replacement in patients with mitral valve regurgitation in a longitudinal setting...
  19. ncbi request reprint Reduced 6-month resource use and costs associated with cilostazol in patients after successful coronary stent implantation: results from the Cilostazol for RESTenosis (CREST) trial
    Zefeng Zhang
    Christiana Care Health System, Newark, DE 19713, USA
    Am Heart J 152:770-6. 2006
    ..4% vs 16%, P = .90) for the 2 treatment groups, but restenosis rate was lower (22.0% vs 34.5%, P = .002) in cilostazol-treated patients. We sought to evaluate resource use, cost, and cost-effectiveness of cilostazol in CREST...
  20. ncbi request reprint The impact of age on outcomes after coronary artery bypass surgery versus stent-assisted percutaneous coronary intervention: one-year results from the Stent or Surgery (SoS) trial
    Zefeng Zhang
    Christiana Care Center for Outcomes Research, Christiana Care Health System, Newark, DE 19713, USA
    Am Heart J 152:1153-60. 2006
    ..Relative outcomes of coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) may differ between younger and older patients. There are no data comparing the age-related CABG versus PCI outcomes in the stent era...
  21. ncbi request reprint Emergency department tachypnea predicts transfer to a higher level of care in the first 24 hours after ED admission
    Heather Farley
    Christiana Care Health System, Newark, DE, USA
    Acad Emerg Med 17:718-22. 2010
    ..The authors hypothesized that vital sign abnormalities detected in the emergency department (ED) can be used to forecast clinical deterioration occurring within 24 hours of hospital admission...
  22. doi request reprint Prepregnancy body mass index as an independent risk factor for pregnancy-induced hypertension
    Deborah B Ehrenthal
    Department of Obstetrics and Gynecology, Christiana Care Health Services, Newark, DE 19718, USA
    J Womens Health (Larchmt) 20:67-72. 2011
    ..With the rising prevalence of obesity, the role of prepregnancy body mass index (BMI) as an independent risk factor for PIH and a target for preconception care is important to explore...
  23. doi request reprint Cost effectiveness of enoxaparin in acute ST-segment elevation myocardial infarction: the ExTRACT-TIMI 25 (Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment-Thrombolysis In Myocardial Infarction 25) study
    Leo Marcoff
    Christiana Care Center for Outcomes Research, Christiana Care Health System, Newark, Delaware 19718, USA
    J Am Coll Cardiol 54:1271-9. 2009
    ..We used a U.S. model of health care costs to examine the cost effectiveness of enoxaparin compared with unfractionated heparin (UFH) as adjunctive therapy for fibrinolysis in patients with ST-segment elevation myocardial infarction (STEMI)...
  24. ncbi request reprint Predictors and outcomes associated with early extubation in older adults undergoing coronary artery bypass surgery
    J L Bezanson
    Scientific Research Solutions, Inc, Roswell, GA, USA
    Am J Crit Care 10:383-90. 2001
    ..The variables comorbid conditions and severity of illness provided better discrimination between extubation groups than a physiological model provided. Both predictive models allowed limited discrimination between groups...
  25. ncbi request reprint Targeting patients undergoing angioplasty for thrombus inhibition: a cost-effectiveness and decision support model
    W S Weintraub
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Circulation 102:392-8. 2000
    ..However, uncertainty exists regarding the cost-effective selection of patients to receive antiplatelet therapy...
  26. ncbi request reprint Angiographic and clinical follow-up of percutaneous revascularization for transplant coronary artery disease
    S J Dempsey
    Center for Heart Failure Therapy, Emory University Hospital, 1364 Clifton Road, N E, Suite F508, Atlanta, GA, 30322, USA
    J Invasive Cardiol 12:311-5. 2000
    ..There are limited data on the use of percutaneous revascularization techniques for transplant coronary artery disease (CAD)...
  27. doi request reprint Survival and neurologic recovery in patients with ST-segment elevation myocardial infarction resuscitated from cardiac arrest
    Vinay R Hosmane
    Department of Medicine Cardiology, Christiana Care Health System, Newark, Delware 19718, USA
    J Am Coll Cardiol 53:409-15. 2009
    ..We examined outcomes of patients resuscitated from cardiac arrest owing to ST-segment elevation myocardial infarction (STEMI) and predictors of survival and neurologic recovery...
  28. doi request reprint Coronary artery disease: revascularization strategies for patients with CAD and diabetes
    G Robert Myers
    Section of Cardiology, Room 2E99, Christiana Hospital, 4755 Ogletown Stanton Road, Newark, DE 19718, USA
    Nat Rev Cardiol 7:364-6. 2010
    ..The results of a new analysis of data from the SYNTAX trial challenge this conventional wisdom and highlight additional coronary revascularization options to physicians and patients...
  29. ncbi request reprint Twenty-year survival after coronary artery surgery: an institutional perspective from Emory University
    William S Weintraub
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Circulation 107:1271-7. 2003
    ..However, uncertainty exists regarding the relationship between long-term survival after CABG and readily available clinical correlates of mortality...
  30. ncbi request reprint Prognostic implication of creatine kinase release after elective percutaneous coronary intervention in the pre-IIb/IIIa antagonist era
    Ziyad Ghazzal
    Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, GA, USA
    Am Heart J 145:1006-12. 2003
    ..We evaluated the significance of creatine phosphokinase level (CPK) elevations in a large cohort of patients who had undergone an elective PCI before the IIb/IIIa receptor antagonist era...
  31. ncbi request reprint Cost and cost-effectiveness studies in heart failure research
    William S Weintraub
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA
    Am Heart J 143:565-76. 2002
    ..In the United States alone, the prevalence is 4.6 million, with an incidence rate of 550,000 new cases a year and approximately 957,000 hospitalizations a year...
  32. ncbi request reprint Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial
    John D Puskas
    Division of Cardiothoracic Surgery, Emory University School of Medicine and Emory Center for Outcomes Research, Atlanta, GA, USA
    JAMA 291:1841-9. 2004
    ..A preliminary report showed OPCAB achieved improved inhospital outcomes, similar completeness of revascularization, and shorter lengths of stay compared with conventional coronary artery bypass grafting (CABG)...
  33. ncbi request reprint Impact of the Duett sealing device on quality of life and hospitalization costs for coronary diagnostic and interventional procedures: Results from the Study of Economic and Quality of Life substudy of the SEAL trial
    Z Zhang
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA
    Am Heart J 142:982-8. 2001
    ..02). CONCLUSIONS: The Duett sealing device was associated with significantly higher functional status at 7 days after the procedure in addition to shortened time to hemostasis and ambulation, with no associated increase in cost...
  34. ncbi request reprint Is a paradigm shift in US healthcare reimbursement inevitable?
    William S Weintraub
    Emory University, Atlanta, GA, USA
    Circulation 109:1448-55. 2004
  35. ncbi request reprint Comparison of outcomes of percutaneous coronary intervention of ostial versus nonostial narrowing of the major epicardial coronary arteries
    Kreton Mavromatis
    Division of Cardiology, Atlanta VA Medical Center, Decatur, Georgia, USA
    Am J Cardiol 94:583-7. 2004
    ..However, at 1 year, patients who underwent ostial PCI had an increased rate of repeat revascularization compared with patients who underwent nonostial, proximal PCI...
  36. doi request reprint Health status outcomes after cardioversion for atrial fibrillation: results from the Assessment of Cardioversion Using Transesophageal Echocardiography (ACUTE) II Trial
    Daniel J Elliott
    University of Pennsylvania Division of General Internal Medicine, Philadelphia, PA, USA
    Am Heart J 156:374.e1-6. 2008
    ..The aim of the study was to compare the health status outcomes of patients who undergo TEE-guided cardioversion with enoxaparin or unfractionated heparin as anticoagulation bridging therapy...
  37. ncbi request reprint Assessing data adequacy for clinical research: reliability and validity of a surgical database
    Judy L Bezanson
    Scientific Research Solutions, Inc, Roswell, GA, USA
    J Nurs Meas 10:155-64. 2002
    ..Using the same external standard to assess both reliability and validity was a significant limitation of this study, which resulted in the same measure of data adequacy by utilizing differing statistical methods...
  38. ncbi request reprint On- versus off-label use of drug-eluting coronary stents in clinical practice (report from the American College of Cardiology National Cardiovascular Data Registry [NCDR])
    Sunil V Rao
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 97:1478-81. 2006
    ..Randomized clinical trials are needed to confirm the efficacy of DESs in these clinical and angiographic settings. These data also highlight the importance of multicenter registries in tracking new technologies...
  39. pmc The vascular effects of cilostazol
    William S Weintraub
    Emory Center for Outcomes Research, Emory University, Atlanta, Georgia 30322, USA
    Can J Cardiol 22:56B-60B. 2006
    ....
  40. ncbi request reprint Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial Veterans Affairs Cooperative Studies Program no. 424
    William E Boden
    VA Connecticut Healthcare System, West Haven, CT, USA
    Am Heart J 151:1173-9. 2006
    ....
  41. ncbi request reprint Impact of diabetes on five-year outcomes after vein graft interventions performed prior to the drug-eluting stent era
    Salman Ashfaq
    University of Kansas School of Medicine Wichita, Wichita, Kansas, USA
    J Invasive Cardiol 18:100-5. 2006
    ....
  42. ncbi request reprint Patterns and outcomes of drug-eluting coronary stent use in clinical practice
    Sunil V Rao
    The Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 152:321-6. 2006
    ..To determine patterns and outcomes of drug-eluting stents (DES) use in clinical practice...
  43. ncbi request reprint The evolving pattern of symptomatic coronary artery disease in the United States and Canada: baseline characteristics of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial
    William E Boden
    VA Connecticut Healthcare System, West Haven, Connecticut, USA
    Am J Cardiol 99:208-12. 2007
    ....
  44. ncbi request reprint Optimal medical therapy with or without PCI for stable coronary disease
    William E Boden
    Western New York Veterans Affairs Healthcare Network and Buffalo General Hospital SUNY, Buffalo, NY 14203, USA
    N Engl J Med 356:1503-16. 2007
    ....
  45. doi request reprint Impact of ethnicity and gender differences on angiographic coronary artery disease prevalence and in-hospital mortality in the American College of Cardiology-National Cardiovascular Data Registry
    Leslee J Shaw
    Emory Program in Cardiovascular Outcomes Research and Epidemiology, 1256 Briarcliff Rd NE, Suite 1 N, Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 117:1787-801. 2008
    ..Although populations referred for coronary angiography are increasingly diverse, there is limited information on coronary artery disease (CAD) prevalence and in-hospital mortality other than for predominately white male patients...
  46. ncbi request reprint The Seattle angina questionnaire: reliability and validity in women with chronic stable angina
    Laura P Kimble
    School of Nursing, Emory University, Atlanta, Georgia 30322, USA
    Heart Dis 4:206-11. 2002
    ..Future research is needed to determine whether examining different combinations of SAQ items might provide a more sensitive assessment of cardiac disease-specific quality of life in women...
  47. ncbi request reprint Long-term cost-effectiveness of early and sustained clopidogrel therapy for up to 1 year in patients undergoing percutaneous coronary intervention after presenting with acute coronary syndromes without ST-segment elevation
    Elizabeth M Mahoney
    New England Research Institutes, Watertown, MA 02472, USA
    Am Heart J 151:219-27. 2006
    ..We evaluated the long-term cost-effectiveness of clopidogrel use for up to 1 year using patient-level outcomes and resource use from PCI-CURE, and estimates of life expectancy gains based on external sources...
  48. ncbi request reprint Rationale and design of the randomized, multicenter, cilostazol for RESTenosis (CREST) trial
    John S Douglas
    Division of Cardiology, Emory Center for Outcomes Research, Emory University School of Medicine, Atlanta, Georgia, USA
    Clin Cardiol 26:451-4. 2003
    ..The CREST trial is a large, rigorously conducted trial that may corroborate the favorable effects of cilostazol on coronary stent restenosis suggested by earlier studies...
  49. ncbi request reprint Gender differences in pain characteristics of chronic stable angina and perceived physical limitation in patients with coronary artery disease
    Laura P Kimble
    Emory University School of Nursing, 1520 Clifton Rd, NE, Atlanta, GA 30322, USA
    Pain 101:45-53. 2003
    ....
  50. ncbi request reprint Economics of sirolimus-eluting stents: drug-eluting stents have really arrived
    William S Weintraub
    Circulation 110:472-4. 2004
  51. ncbi request reprint Methods for the economic and quality of life supplement to the cilostazol for RESTenosis (CREST) trial
    William S Weintraub
    Division of Cardiology, Emory University, Atlanta, Georgia, USA
    J Invasive Cardiol 16:257-9. 2004
    ..To determine economic and quality of life outcomes for the Cilostazol for RESTenosis (CREST) trial, which is investigating the efficacy of cilostazol vs. placebo in preventing post-stent restenosis...
  52. ncbi request reprint Evaluation of the American College of Cardiology/American Heart Association and the Society for Coronary Angiography and Interventions lesion classification system in the current "stent era" of coronary interventions (from the ACC-National Cardiovascular
    Ronald J Krone
    Department of Medicine, Washington University, St Louis, Missouri, USA
    Am J Cardiol 92:389-94. 2003
    ....
  53. ncbi request reprint Relative benefit of coronary artery bypass grafting versus stent-assisted percutaneous coronary intervention for angina pectoris and multivessel coronary disease in women versus men (one-year results from the Stent or Surgery trial)
    Zefeng Zhang
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    Am J Cardiol 93:404-9. 2004
    ..049 for the interaction among treatment, gender, and follow-up for the quality of life domain). Although CABG may be superior to PCI in men, in women, at 1 year after intervention, both procedures appear equally effective...
  54. ncbi request reprint Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial
    Zefeng Zhang
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 108:1694-700. 2003
    ..Few data are available regarding the comparative improvement in disease-specific health status after CABG versus percutaneous coronary intervention (PCI) in the era of coronary stenting...
  55. ncbi request reprint Restenosis: are the implications changing?
    Jason H Cole
    Am Heart J 147:197-9. 2004
  56. ncbi request reprint Implications of upstream glycoprotein IIb/IIIa inhibition and coronary artery stenting in the invasive management of unstable angina/non-ST-elevation myocardial infarction: a comparison of the Thrombolysis In Myocardial Infarction (TIMI) IIIB trial and th
    Marc S Sabatine
    TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Circulation 109:874-80. 2004
    ..We sought to examine the effect of these advances on clinical outcomes and the benefits of an early invasive strategy in UA/NSTEMI...
  57. ncbi request reprint Are stenting and glycoprotein IIb/IIIa blockade of good value in primary percutaneous coronary intervention?
    Jason H Cole
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 108:2831-3. 2003
  58. ncbi request reprint Cost and cost-effectiveness of an early invasive vs conservative strategy for the treatment of unstable angina and non-ST-segment elevation myocardial infarction
    Elizabeth M Mahoney
    Emory Center for Outcomes Research, Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Rd, Suite 1N, Atlanta, GA 30306, USA
    JAMA 288:1851-8. 2002
    ....
  59. ncbi request reprint Cost-effectiveness of targeting patients undergoing cardiac surgery for therapy with intravenous amiodarone to prevent atrial fibrillation
    Elizabeth M Mahoney
    Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia, USA
    J Am Coll Cardiol 40:737-45. 2002
    ..This study evaluated the cost-effectiveness of administering prophylactic intravenous (IV) amiodarone therapy to patients undergoing cardiac surgery according to their predicted risk of postoperative atrial fibrillation...
  60. ncbi request reprint Long-term cost effectiveness of early and sustained dual oral antiplatelet therapy with clopidogrel given for up to one year after percutaneous coronary intervention results: from the Clopidogrel for the Reduction of Events During Observation (CREDO) tria
    Sean C Beinart
    Emory University, Atlanta, Georgia, USA
    J Am Coll Cardiol 46:761-9. 2005
    ..This study sought to evaluate the long-term cost effectiveness of a clopidogrel loading strategy before percutaneous coronary intervention (PCI) followed by continued treatment for one year...
  61. ncbi request reprint The impact of acute coronary syndrome on clinical, economic, and cardiac-specific health status after coronary artery bypass surgery versus stent-assisted percutaneous coronary intervention: 1-year results from the stent or surgery (SoS) trial
    Zefeng Zhang
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Am Heart J 150:175-81. 2005
    ..Data are limited regarding the impact of acute coronary syndromes (ACSs) on the relative benefits of coronary artery bypass grafting (CABG) versus stent-assisted percutaneous coronary intervention (PCI)...
  62. ncbi request reprint Influence of race on death and ischemic complications in patients with non-ST-elevation acute coronary syndromes despite modern, protocol-guided treatment
    Marc S Sabatine
    TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115
    Circulation 111:1217-24. 2005
    ..Whether the disparate outcomes exist independently of potential biases in treatment patterns remains unclear...
  63. ncbi request reprint Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevation
    William S Weintraub
    Emory University, Atlanta, Georgia, USA
    J Am Coll Cardiol 45:838-45. 2005
    ..We sought to evaluate the long-term cost-effectiveness of clopidogrel for up to one year after an acute coronary syndrome (ACS) without ST-segment elevation...
  64. ncbi request reprint Cost-effectiveness of eplerenone compared with placebo in patients with myocardial infarction complicated by left ventricular dysfunction and heart failure
    William S Weintraub
    Emory University, 1256 Briarcliff Rd, Suite 1N, Atlanta, GA 30306, USA
    Circulation 111:1106-13. 2005
    ..The present study was performed to evaluate the cost-effectiveness of eplerenone compared with placebo in these patients...
  65. ncbi request reprint The cost-effectiveness of the use of clopidogrel in acute coronary syndromes in five countries based upon the CURE study
    Andre Lamy
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Eur J Cardiovasc Prev Rehabil 11:460-5. 2004
    ..The CURE study demonstrated that clopidogrel prevents a range of ischaemic cardiovascular events in patients with Acute Coronary Syndromes (unstable angina or non-ST-segment elevation MI)...
  66. ncbi request reprint Neuropsychological outcome after percutaneous coronary intervention or coronary artery bypass grafting: results from the Stent or Surgery (SoS) Trial
    Peter Wahrborg
    Department of Cardiology, Sahlgrenska University Hospital, S 413 45 Gothenburg Sweden
    Circulation 110:3411-7. 2004
    ..However, little is known about the impact of percutaneous coronary intervention (PCI) on neuropsychological outcome...
  67. ncbi request reprint Summary of special topics presentations of the American College of Cardiology 52nd annual meeting, 2003
    William S Weintraub
    Department of Medicine, Emory University, Atlanta, Georgia 30306, USA
    J Am Coll Cardiol 42:383-5. 2003
  68. ncbi request reprint Association between gender and in-hospital mortality after percutaneous coronary intervention according to age
    Jerome L Abramson
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, 1256 Briarcliff Road, Suite 1 North, Atlanta, GA 30306, USA
    Am J Cardiol 91:968-71, A4. 2003
  69. ncbi request reprint Development of a risk adjustment mortality model using the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR) experience: 1998-2000
    Richard E Shaw
    San Francisco Heart Institute at Seton Medical Center, Daly City, California 94015, USA
    J Am Coll Cardiol 39:1104-12. 2002
    ..We sought to develop and evaluate a risk adjustment model for in-hospital mortality following percutaneous coronary intervention (PCI) procedures using data from a large, multi-center registry...
  70. ncbi request reprint Long-term follow-up of coronary artery disease presenting in young adults
    Jason H Cole
    Emory Center for Outcomes Research and Section of Preventive Cardiology, Division of Cardiology, Emory University School of Medicine, Emory University, 1525 Clifton Road, Atlanta, GA 30322, USA
    J Am Coll Cardiol 41:521-8. 2003
    ..This study evaluated long-term survival and predictors of elevated risk for young adults diagnosed with coronary artery disease (CAD)...
  71. ncbi request reprint Expanding the outcomes in clinical trials of heart failure: the quality of life and economic components of EPHESUS (EPlerenone's neuroHormonal Efficacy and SUrvival Study)
    John A Spertus
    Mid America Heart Institute and the University of Missouri, Kansas City, MO, USA
    Am Heart J 143:636-42. 2002
    ....
  72. ncbi request reprint A comparison of self-selectivity corrections in economic evaluations and outcomes research
    Jinook Jeong
    Department of Economics, Yonsei University, Seoul, Korea, and Ralph H Johnson VA Medical Center, Charleston, SC, USA
    Value Health 8:656-66. 2005
    ..This article reviews and empirically tests the two alternative selectivity correction methods to give a reality-based evaluation...
  73. ncbi request reprint Association of high serum creatinine and anemia increases the risk of coronary events: results from the prospective community-based atherosclerosis risk in communities (ARIC) study
    Claudine T Jurkovitz
    Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    J Am Soc Nephrol 14:2919-25. 2003
    ..86 to 1.67). In conclusion, this study indicates that high Scr is associated with almost a threefold risk of CHD among middle-aged people with anemia, whereas no increased risk is found in people with high Scr in the absence of anemia...
  74. ncbi request reprint Culprit-only or multivessel revascularization in patients with acute coronary syndromes: an American College of Cardiology National Cardiovascular Database Registry report
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Am Heart J 155:140-6. 2008
    ..Although an early invasive strategy improves outcome in these patients, there are limited data on culprit-only, single-vessel (SV) percutaneous coronary intervention (PCI) or MV PCI in the NSTE ACS setting...
  75. ncbi request reprint Cost-effectiveness of eplerenone in patients with left ventricular dysfunction after myocardial infarction--an analysis of the EPHESUS study from a Swiss perspective
    Thomas D Szucs
    Institute of Social and Preventive Medicine, University of Zurich, Gloriastrasse 18a, CH 8006 Zurich, Switzerland
    Cardiovasc Drugs Ther 20:193-204. 2006
    ..The EPHESUS pharmacoeconomic analysis was performed to evaluate the cost-effectiveness of eplerenone in the Swiss setting...
  76. ncbi request reprint The synergistic effect of heart disease and diabetes on self-management, symptoms, and health status
    Christi Deaton
    The University of Manchester, Manchester, United Kingdom
    Heart Lung 35:315-23. 2006
    ..Coronary heart disease (CHD) and diabetes may have synergistic effects on symptoms, self-management, and general and cardiac-specific health status...
  77. ncbi request reprint Variability in the clinical status of patients with advanced heart failure
    Paul J Hauptman
    Department of Medicine, Saint Louis University School of Medicine, Missouri, USA
    J Card Fail 10:397-402. 2004
    ..The frequency of such follow-up is not established and is likely to depend on the natural history and variability of patients' health status and the availability and use of appropriate treatments...
  78. ncbi request reprint Time course of depression and outcome of myocardial infarction
    Susmita Parashar
    Divisions of General Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Intern Med 166:2035-43. 2006
    ..Our objective was to evaluate the prognostic importance of transient, new, or persistent depression on outcomes at 6 months after MI...
  79. ncbi request reprint Multicenter experience in revascularization of very elderly patients
    Eric D Peterson
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 148:486-92. 2004
    ..We pooled the largest PCI and CABG clinical registries in the United States to better understand revascularization procedure use, risks and outcomes in patients aged > or =75 years...
  80. ncbi request reprint Risk-adjusted mortality analysis of percutaneous coronary interventions by American College of Cardiology/American Heart Association guidelines recommendations
    H Vernon Anderson
    University of Texas Health Science Center, Houston, Texas, USA
    Am J Cardiol 99:189-96. 2007
    ..With further refinement, these methods should be able to be used as powerful analytic tools for quality assurance and appropriateness purposes...
  81. ncbi request reprint The effect of routine, early invasive management on outcome for elderly patients with non-ST-segment elevation acute coronary syndromes
    Richard G Bach
    Cardiovascular Division, Washington University Medical Center, St Louis, Missouri 63110, USA
    Ann Intern Med 141:186-95. 2004
    ..Although increasing age is an important risk factor for adverse outcome among patients with acute coronary syndromes, elderly patients are more often managed conservatively...
  82. ncbi request reprint Economic analysis of a transesophageal echocardiography-guided approach to cardioversion of patients with atrial fibrillation: the ACUTE economic data at eight weeks
    Allan L Klein
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 43:1217-24. 2004
    ....
  83. ncbi request reprint Predictors of weight change in overweight patients with myocardial infarction
    Yazid Y Fadl
    Washington University in St Louis, St Louis, MO, USA
    Am Heart J 154:711-7. 2007
    ..Weight loss is recommended among overweight survivors of myocardial infarction (MI). This study describes patterns of weight change among overweight patients with MI and identifies factors associated with weight change...
  84. ncbi request reprint A contemporary overview of percutaneous coronary interventions. The American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR)
    H Vernon Anderson
    Texas Heart Institute and the University of Texas, Houston 77030, USA
    J Am Coll Cardiol 39:1096-103. 2002
    ..These data reconfirm overall acceptable results that are consistent with other reported data, but also confirm large variations between individual institutions...

Research Grants1

  1. EXERCISE AND CARDIOVASCULAR DISEASE
    William Weintraub; Fiscal Year: 2003
    ..Not only existing markers of oxidative stress, but also novel surrogate markers, such as, plasma soluble VCAM-l, myeloperoxidase, and autoantbodies to oxidatively modified proteins will be measured. ..