Y M Chook

Summary

Country: USA

Publications

  1. ncbi request reprint Karyopherins and nuclear import
    Y M Chook
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Curr Opin Struct Biol 11:703-15. 2001
  2. ncbi request reprint Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp
    Y M Chook
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    Nature 399:230-7. 1999
  3. ncbi request reprint The monofunctional chorismate mutase from Bacillus subtilis. Structure determination of chorismate mutase and its complexes with a transition state analog and prephenate, and implications for the mechanism of the enzymatic reaction
    Y M Chook
    Department of Chemistry, Harvard University, Cambridge, MA 02138
    J Mol Biol 240:476-500. 1994
  4. pmc Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog
    Y M Chook
    Gibbs Chemical Laboratory, Harvard University, Cambridge, MA 02138
    Proc Natl Acad Sci U S A 90:8600-3. 1993
  5. ncbi request reprint The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2
    Y M Chook
    Department of Biochemistry, University of Toronto, Ontario, Canada
    J Biol Chem 271:30472-8. 1996

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Karyopherins and nuclear import
    Y M Chook
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Curr Opin Struct Biol 11:703-15. 2001
    ..These karyopherin structures provide valuable insights into understanding the molecular mechanism of nuclear import, especially substrate recognition, substrate release by GTPase and interactions with the nuclear pore complex...
  2. ncbi request reprint Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp
    Y M Chook
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    Nature 399:230-7. 1999
    ....
  3. ncbi request reprint The monofunctional chorismate mutase from Bacillus subtilis. Structure determination of chorismate mutase and its complexes with a transition state analog and prephenate, and implications for the mechanism of the enzymatic reaction
    Y M Chook
    Department of Chemistry, Harvard University, Cambridge, MA 02138
    J Mol Biol 240:476-500. 1994
    ....
  4. pmc Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog
    Y M Chook
    Gibbs Chemical Laboratory, Harvard University, Cambridge, MA 02138
    Proc Natl Acad Sci U S A 90:8600-3. 1993
    ..182 for a model that includes 1388 residues, 12 inhibitor molecules, and 530 water molecules in the asymmetric unit. In each trimer, three equivalent active sites are located at the interfaces of two adjacent subunits...
  5. ncbi request reprint The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2
    Y M Chook
    Department of Biochemistry, University of Toronto, Ontario, Canada
    J Biol Chem 271:30472-8. 1996
    ....