Irene E Zohn

Summary

Affiliation: Children's National Medical Center
Country: USA

Publications

  1. pmc Does the cranial mesenchyme contribute to neural fold elevation during neurulation?
    Irene E Zohn
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Birth Defects Res A Clin Mol Teratol 94:841-8. 2012
  2. doi request reprint Mouse as a model for multifactorial inheritance of neural tube defects
    Irene E Zohn
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Birth Defects Res C Embryo Today 96:193-205. 2012
  3. pmc Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Galphai, Galphaq and Rho-dependent signaling pathways
    Anurag Singh
    Linebergher Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA
    J Mol Signal 5:11. 2010
  4. doi request reprint The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation
    Irene E Zohn
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Birth Defects Res A Clin Mol Teratol 88:593-600. 2010
  5. pmc Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme
    Anjali A Sarkar
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Cell Biol 196:789-800. 2012
  6. pmc The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure
    Jinzhe Mao
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Development 137:3079-88. 2010
  7. ncbi request reprint Hectd1 is required for development of the junctional zone of the placenta
    Anjali A Sarkar
    Center for Neuroscience Research, Children s Research Institute, and Children s National Medical Center, Washington, DC 20010, USA
    Dev Biol 392:368-80. 2014
  8. doi request reprint Modeling neural tube defects in the mouse
    Irene E Zohn
    Children s Research Institute, Children s National Medical Center, Washington, DC, USA
    Curr Top Dev Biol 84:1-35. 2008

Collaborators

  • Anjali A Sarkar
  • Anurag Singh
  • Jinzhe Mao
  • Jonathon T Hill
  • Samer J Nuwayhid
  • Anthony S LaMantia
  • Frederick Ghandchi
  • Thomas Maynard
  • Lee Niswander
  • Joshua G Corbin
  • Channing J Der
  • Sunita Warrier
  • Jose L Boyer
  • David M McKean

Detail Information

Publications9

  1. pmc Does the cranial mesenchyme contribute to neural fold elevation during neurulation?
    Irene E Zohn
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Birth Defects Res A Clin Mol Teratol 94:841-8. 2012
    ..In this article, we review the evidence implicating the cranial mesenchyme in providing a driving force for neural fold elevation to evaluate whether there are sufficient data to support this hypothesis...
  2. doi request reprint Mouse as a model for multifactorial inheritance of neural tube defects
    Irene E Zohn
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Birth Defects Res C Embryo Today 96:193-205. 2012
    ..This review provides examples of how multifactorial inheritance of NTDs can be modeled in the mouse...
  3. pmc Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Galphai, Galphaq and Rho-dependent signaling pathways
    Anurag Singh
    Linebergher Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA
    J Mol Signal 5:11. 2010
    ..Nucleotide-actived P2Y receptors play critical roles in the growth of tumor cells by regulating cellular proliferation, differentiation and survival...
  4. doi request reprint The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation
    Irene E Zohn
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Birth Defects Res A Clin Mol Teratol 88:593-600. 2010
    ....
  5. pmc Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme
    Anjali A Sarkar
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Cell Biol 196:789-800. 2012
    ....
  6. pmc The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure
    Jinzhe Mao
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Development 137:3079-88. 2010
    ..Finally, we demonstrate that this loss of forebrain maintenance is due in part to the iron deficiency that results from the absence of fully functional Fpn1...
  7. ncbi request reprint Hectd1 is required for development of the junctional zone of the placenta
    Anjali A Sarkar
    Center for Neuroscience Research, Children s Research Institute, and Children s National Medical Center, Washington, DC 20010, USA
    Dev Biol 392:368-80. 2014
    ..Together these data demonstrate that Hectd1 is required for development of multiple cell types within the junctional zone of the placenta. ..
  8. doi request reprint Modeling neural tube defects in the mouse
    Irene E Zohn
    Children s Research Institute, Children s National Medical Center, Washington, DC, USA
    Curr Top Dev Biol 84:1-35. 2008
    ..In some cases these studies have led to development of approaches to prevent NTDs and provide an understanding of the underlying molecular mechanism of these therapies prevent NTDs...

Research Grants1

  1. Novel Ubiquitin Dependent Pathways Regulating Neural Tube Closure and Placentatio
    Irene E Zohn; Fiscal Year: 2010
    ..The understanding gained from the experiments proposed here may lead to strategies to minimize these complications of pregnancy. ..