Research Topics
| Wayne TworetzkySummaryAffiliation: Children's Hospital Country: USA Publications
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Detail Information
Publications
Association between cardiac tumors and tuberous sclerosis in the fetus and neonateWayne Tworetzky
Department of Cardiology, Children s Hospital, Boston, Massachusetts 02115, USA
Am J Cardiol 92:487-9. 2003..Tuberous sclerosis was present in 68 patients diagnosed with a cardiac tumor in utero or during the neonatal period, including 61 of 64 with multiple tumors...- Fetal interventions for cardiac defectsWayne Tworetzky
Department of Pediatrics, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Pediatr Clin North Am 51:1503-13, vii. 2004..Finally, the technical aspects and procedural considerations are reviewed... 
In utero valvuloplasty for pulmonary atresia with hypoplastic right ventricle: techniques and outcomesWayne Tworetzky
Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
Pediatrics 124:e510-8. 2009....- Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful interventionWayne Tworetzky
Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston MA 02115, USA
Circulation 110:2125-31. 2004..Fetuses meeting the first criterion are undefined, and previous reports of fetal AS dilation have not evaluated the impact of intervention on in utero growth of left heart structures... - Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndromeDoff B McElhinney
Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
Circulation 120:1482-90. 2009..Prenatal balloon aortic valvuloplasty may improve left heart growth and function, possibly preventing evolution to hypoplastic left heart syndrome... - Assessment of left ventricular endocardial fibroelastosis in fetuses with aortic stenosis and evolving hypoplastic left heart syndromeDoff B McElhinney
Department of Cardiology, Children s Hospital Boston, Massachusetts, USA
Am J Cardiol 106:1792-7. 2010..Additional experience and external validation of the EFE grading scoring system are necessary... - Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal interventionKaarin Mäkikallio
Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, MA, USA
Circulation 113:1401-5. 2006..The aim of this study was to define echocardiographic features associated with progression of midgestation fetal AS to HLHS... - Fetal tricuspid valve size and growth as predictors of outcome in pulmonary atresia with intact ventricular septumJoshua W Salvin
Department of Cardiology, Cardiac ICU Office, Farley 6, Children s Hospital Boston, 300 Longwood Ave, Boston, Massachusetts 02115, USA
Pediatrics 118:e415-20. 2006..The objective of this study was to determine whether the size and rate of growth of the fetal tricuspid valve predict neonatal anatomy and biventricular repair... 
Primary left ventricular rehabilitation is effective in maintaining two-ventricle physiology in the borderline left heartSitaram M Emani
Children s Hospital Boston, Boston, MA 02115, USA
J Thorac Cardiovasc Surg 138:1276-82. 2009..We studied the effects of left ventricular rehabilitation--endocardial fibroelastosis resection with mitral or aortic valvuloplasty--on left ventricular function and clinical outcomes...- Aortic valvuloplasty in the fetus: technical characteristics of successful balloon dilationAudrey C Marshall
Department of Cardiology and Department of Surgery, Children's Hospital Boston, Boston, Massachusetts 02115, USA
J Pediatr 147:535-9. 2005..The observation of spontaneous improvement in postdilation aortic regurgitation further suggests that fetal valve tissue behaves uniquely... - Results of in utero atrial septoplasty in fetuses with hypoplastic left heart syndromeAudrey C Marshall
Department of Cardiology, Children s Hospital Boston, Boston 02115, USA
Prenat Diagn 28:1023-8. 2008..We sought to assess the effect of prenatal intervention intended to create atrial septal defects in fetuses with this diagnosis... - Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septumMelanie Vogel
Department of Cardiology, Children s Hospital Boston, and Pediatrics, Harvard Medical School, Boston, MA 02115, USA
Fetal Diagn Ther 27:40-5. 2010..Indomethacin promotes closure of the DA in newborns and in fetal life, a potentially life threatening complication in fetuses with ductus-dependent congenital heart disease... - Outcome of fetuses and infants with double inlet single left ventricleEdythe B C Tham
Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 101:1652-6. 2008..During this same period, postnatal survival has improved substantially. Neonatal surgery of any type was the only independent risk factor for worse survival... - Aortic stenosis and severe mitral regurgitation in the fetus resulting in giant left atrium and hydrops: pathophysiology, outcomes, and preliminary experience with pre-natal cardiac interventionMelanie Vogel
Department of Cardiology, The Advanced Fetal Care Center, Children s Hospital Boston, Harvard Medical School, Massachusetts, USA
J Am Coll Cardiol 57:348-55. 2011.... - Ebstein's malformation of the tricuspid valve: short-term outcomes of the "cone procedure" versus conventional surgeryMelanie Vogel
Departments of Cardiology and Cardiac Surgery, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Congenit Heart Dis 7:50-8. 2012..The newer cone procedure aims to construct a funnel-like valve out of native leaflets, obviating problems with artificial valves... - Pathophysiology, management, and outcomes of fetal hemodynamic instability during prenatal cardiac interventionArielle Mizrahi Arnaud
Department of Anesthesiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatr Res 62:325-30. 2007..Hemopericardium may be causative in a subset of fetuses... - Creation of an atrial septal defect in utero for fetuses with hypoplastic left heart syndrome and intact or highly restrictive atrial septumAudrey C Marshall
Department of Cardiology, Children s Hospital and Pediatrics, Harvard Medical School, 300 Longwood Ave, Boston, Mass 02115, USA
Circulation 110:253-8. 2004..Prenatal left atrial decompression has been suggested as a means of improving these outcomes. This study reports the feasibility of fetal catheterization to create an interatrial communication and describes technical considerations... - Cerebral blood flow characteristics and biometry in fetuses undergoing prenatal intervention for aortic stenosis with evolving hypoplastic left heart syndromeDoff B McElhinney
Department of Cardiology, Children s Hospital Boston, and Pediatrics, Harvard Medical School, Boston, MA, USA
Ultrasound Med Biol 36:29-37. 2010..The mechanisms and significance of these abnormalities are unknown. Prenatal aortic valvuloplasty did not have a major impact on these indices. (E-mail: doff.mcelhinney@cardio.chboston.org)... - Postnatal angiographic appearance of left ventricular myocardium in fetal patients with aortic stenosis having in-utero aortic valvuloplastyBabar Sultan Hasan
Department of Cardiology, Children s Hospital Boston, Massachusetts, USA
Am J Cardiol 104:1271-5. 2009..In all cases, the septal segments were smooth. In conclusion, patients after FAV have angiographically abnormal left ventricles, commonly involving extensive trabeculations of the free wall, but without septal involvement... - Staged left ventricular recruitment after single-ventricle palliation in patients with borderline left heart hypoplasiaSitaram M Emani
Departments of Cardiac Surgery and Cardiology, Children s Hospital Boston, Boston, Massachusetts Electronic address
J Am Coll Cardiol 60:1966-74. 2012..The goal of this study was to review results of a novel management strategy intended to rehabilitate the left heart (LH) in patients with LH hypoplasia who have undergone single-ventricle palliation (SVP)... - Fetal diagnosis of interrupted aortic archMelanie Vogel
Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 105:727-34. 2010..Despite the diagnostic challenges, the frequency of prenatal diagnosis of the IAA is increasing... - Early reintervention on the pulmonary arteries and right ventricular outflow tract after neonatal or early infant repair of truncus arteriosus using homograft conduitsAmalia M Lund
Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 108:106-13. 2011..A smaller conduit size was associated with early RVOT/PA reintervention. The branch PA size was normal before surgery, suggesting that the PA stenosis in these patients resulted from factors other than intrinsic stenosis or hypoplasia... - Postnatal left ventricular diastolic function after fetal aortic valvuloplastyKevin G Friedman
Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 108:556-60. 2011..LV diastolic dysfunction in this unique population may have important implications on long-term risk of left atrial and subsequent pulmonary hypertension... - Usefulness of magnetic resonance imaging of left ventricular endocardial fibroelastosis in infants after fetal intervention for aortic valve stenosisWayne Tworetzky
Department of Cardiology, Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 96:1568-70. 2005..The preoperative mapping of EFE followed by extensive resection led to biventricular physiology in 2 patients... - Association of socioeconomic position and medical insurance with fetal diagnosis of critical congenital heart diseaseVasum Peiris
Department of Cardiology, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
Circ Cardiovasc Qual Outcomes 2:354-60. 2009..We sought to evaluate whether PD of critical congenital heart disease is related to socioeconomic (SE) position, medical insurance, and race... - Improving outcomes in fetuses and neonates with congenital displacement (Ebstein's malformation) or dysplasia of the tricuspid valveDoff B McElhinney
Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 96:582-6. 2005..To improve outcomes in this group of high-risk patients, novel approaches to management may be indicated... - Cardiac anomalies in the fetusChristopher G B Turner
Department of Surgery, Children s Hospital Boston, Boston, MA 02115, USA
Clin Perinatol 36:439-49, xi. 2009.... - Circumferential and longitudinal ventricular strain in the normal human fetusTetsuko Ishii
Department of Cardiology, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Soc Echocardiogr 25:105-11. 2012..Normal data on longitudinal strain have been reported for human fetuses. The aim of this study was to define circumferential left ventricular (LV) strain in a normal fetal population... - Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: surgical experience from a single centerVladimiro L Vida
Department of Cardiac Surgery, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Ann Thorac Surg 84:581-5; discussion 586. 2007..The purpose of this review is to summarize recent surgical outcomes for these patients at our center and to identify predictors... - Matrix-array 3-dimensional echocardiographic assessment of volumes, mass, and ejection fraction in young pediatric patients with a functional single ventricle: a comparison study with cardiac magnetic resonanceBrian D Soriano
Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Circulation 117:1842-8. 2008.... - Hypoplastic left heart syndrome: current considerations and expectationsJeffrey A Feinstein
Department of Pediatrics, Stanford University School of Medicine, Lucile Salter Packard Children s Hospital, Palo Alto, California 94304, USA
J Am Coll Cardiol 59:S1-42. 2012..Issues surrounding the genetics of HLHS, developmental outcomes, and quality of life are addressed in addition to the many other considerations for caring for this group of complex patients... - Balloon valvuloplasty for congenital heart disease in the fetusWayne Tworetzky
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Clin Perinatol 30:541-50. 2003..Each discipline has specific skills for providing safe access to the fetus, performing the procedure, and providing perioperative care... - Truncus arteriosus: diagnostic accuracy, outcomes, and impact of prenatal diagnosisTara M Swanson
Department of Cardiology, Children s Hospital Boston, Boston, MA 02115, USA
Pediatr Cardiol 30:256-61. 2009..Prenatal diagnosis of TA remains challenging and is associated with a high rate of elective termination. Fetal diagnosis was associated with younger age at repair but was not associated with improved neonatal survival... - Pulmonary venous pathway obstruction from recurrent restriction at atrial septum late after Fontan procedureMassimo A Padalino
Department of Cardiac Surgery, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
J Thorac Cardiovasc Surg 127:281-3. 2004 - Outcome after prenatal diagnosis of tricuspid atresia: a multicenter experienceRachel M Wald
The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Am Heart J 153:772-8. 2007..The outcome of prenatally diagnosed tricuspid atresia (TA) is undefined. We sought to characterize clinical and echocardiographic features of fetal TA and to determine factors associated with mortality... - Fast block flow tracking of atrial septal defects in 4D echocardiographyMarius George Linguraru
Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA
Med Image Anal 12:397-412. 2008..We report consistent results on clinical intra-operative images and retrieve the cardiac cycle (in ungated images) from error analysis. Quantitative results are evaluated on synthetic data with maximum tracking errors of 1 voxel...