Affiliation: Children's National Medical Center
- Improving hand hygiene compliance in health care workers: Strategies and impact on patient outcomesXiaoyan Song
Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC Division of Infectious Disease, Children s National Medical Center, Washington, DC Electronic address
Am J Infect Control 41:e101-5. 2013..We described a systematic process for improving hand hygiene (HH) compliance in health care providers and assessed the impact of HH on patient outcomes...
- Comparison of pandemic and seasonal influenza A infections in pediatric patients: were they different?Xiaoyan Song
Children s National Medical Center, Washington, DC 20010, USA
Influenza Other Respir Viruses 6:25-7. 2012..6% versus 9.0%, P = 0.07) than those hospitalized for seasonal influenza A infections (n = 44), this study found no significant difference between the two comparison groups with regards of other clinical and epidemiological features...
- A stepwise approach to control an outbreak and ongoing transmission of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unitXiaoyan Song
Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA
Am J Infect Control 38:607-11. 2010..Preventing methicillin-resistant Staphylococcus aureus (MRSA) transmission in health care facilities where MRSA is endemic is challenging yet critical...
- Rising economic impact of clostridium difficile-associated disease in adult hospitalized patient populationXiaoyan Song
Johns Hopkins Medical Institutes, Baltimore, Maryland, USA
Infect Control Hosp Epidemiol 29:823-8. 2008..Clostridium difficile-associated disease (CDAD) is responsible for increased morbidity and a substantial economic burden. Incidences of CDAD, including those with a severe course of illness, have been increasing rapidly...
- Clinical and economic impact of methicillin-resistant Staphylococcus aureus colonization or infection on neonates in intensive care unitsXiaoyan Song
Children s National Medical Center and George Washington University Medical Center, Washington, DC 20010, USA
Infect Control Hosp Epidemiol 31:177-82. 2010..This study aimed to determine the clinical and economic impact of MRSA colonization or infection on infants and to measure excess mortality, length of stay, and hospital charges attributable to MRSA...
- Daily chlorhexidine bathing to reduce bacteraemia in critically ill children: a multicentre, cluster-randomised, crossover trialAaron M Milstone
Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Lancet 381:1099-106. 2013..Our objective was to assess whether daily bathing in chlorhexidine gluconate (CHG) compared with standard bathing practices would reduce bacteraemia in critically ill children...
- Increased catheter-related bloodstream infection rates after the introduction of a new mechanical valve intravenous access portLisa L Maragakis
Department of Hospital Epidemiology and Infection Control, The John Hopkins Hospital, Baltimore, Maryland, USA
Infect Control Hosp Epidemiol 27:67-70. 2006..We report a significant increase in catheter-related bloodstream infections after the introduction of a new needle-free positive-pressure mechanical valve intravenous access port at our institution...
- Impact of different methods of feedback to clinicians after postprescription antimicrobial review based on the Centers For Disease Control and Prevention's 12 Steps to Prevent Antimicrobial Resistance Among Hospitalized AdultsSara E Cosgrove
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Infect Control Hosp Epidemiol 28:641-6. 2007....
- Unrecognized burden of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus carriage in the pediatric intensive care unitAaron M Milstone
Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Infect Control Hosp Epidemiol 29:1174-6. 2008..This weekly surveillance enabled more accurate estimates of the incidence rates of MRSA and VRE carriage and led to an increased number of isolation-days for patients...
- Risk of mortality with a bloodstream infection is higher in the less severely ill at admissionPeter W Kim
VA Maryland Health Care System, 100 N Greene St lower level, Baltimore, MD 21201, USA
Am J Respir Crit Care Med 171:616-20. 2005..Health care-associated bloodstream infections are common in critically ill patients; however, investigators have had difficulty in quantifying the clinical impact of these infections given the high expected mortality among these patients...
- Effect of nosocomial vancomycin-resistant enterococcal bacteremia on mortality, length of stay, and costsXiaoyan Song
Department of Hospital Epidemiology and Infection Control, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Infect Control Hosp Epidemiol 24:251-6. 2003..To determine the impact of vancomycin-resistant enterococcal bacteremia on patient outcomes and costs by assessing mortality, excess length of stay, and charges attributable to it...
- An outbreak of multidrug-resistant Acinetobacter baumannii associated with pulsatile lavage wound treatmentLisa L Maragakis
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
JAMA 292:3006-11. 2004..Infection control precautions are not routinely used during the procedure and are not included in pulsatile lavage equipment package labeling...
- Bronchoscope reprocessing and infection prevention and control: bronchoscopy-specific guidelines are neededArjun Srinivasan
Divisions of Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, MD 21287 6284, USA
Chest 125:307-14. 2004..It has been recommended that bronchoscopists familiarize themselves with national recommendations for bronchoscope reprocessing practices, but the extent of guideline awareness is unclear...
- A multicenter outcomes analysis of children with severe viral respiratory infection due to human metapneumovirusMichael C Spaeder
Division of Critical Care Medicine, Children s National Medical Center, Washington, DC, USA
Pediatr Crit Care Med 14:268-72. 2013..To investigate the impact of human metapneumovirus on morbidity and mortality outcomes in children with severe viral respiratory infection...
- Evolving epidemiology of pediatric Staphylococcus aureus cutaneous infections in a Baltimore hospitalAaron E Chen
Department of Pediatrics, The Johns Hopkins University, Baltimore, MD, USA
Pediatr Emerg Care 22:717-23. 2006....
- Timing of preoperative antibiotic prophylaxis: a modifiable risk factor for deep surgical site infections after pediatric spinal fusionAaron M Milstone
Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Pediatr Infect Dis J 27:704-8. 2008..Risk factors for these infections among children are poorly characterized...
- Identification and eradication of methicillin-resistant Staphylococcus aureus colonization in the neonatal intensive care unit: results of a national surveyAaron M Milstone
Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Infect Control Hosp Epidemiol 31:766-8. 2010..Evidence-based prevention strategies for MRSA transmission and infection are needed...
- A multicenter outcomes analysis of children with severe rhino/enteroviral respiratory infection*Michael C Spaeder
1Division of Critical Care Medicine, Children s National Health System, Washington, DC 2Division of Pediatric Critical Care Medicine, University of Maryland Medical Center, Baltimore, MD 3Division of Pediatric Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD 4Biostatistics Center, George Washington University, Rockville, MD 5Department of Pediatrics, University of Maryland Medical Center, Baltimore, MD 6Division of Infectious Disease, Children s National Health System, Washington, DC
Pediatr Crit Care Med 16:119-23. 2015..To investigate the impact of human rhino/enteroviruses on morbidity and mortality outcomes in children with severe viral respiratory infection...
- Risk factors for molecular detection of adenovirus in pediatric hematopoietic stem cell transplantation recipientsTheresa Watson
Division of Cancer and Blood Disorders, Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010, USA
Biol Blood Marrow Transplant 18:1227-34. 2012....
- Low caloric intake is associated with nosocomial bloodstream infections in patients in the medical intensive care unitLewis Rubinson
Johns Hopkins University, Department of Medicine, Baltimore, MD, USA
Crit Care Med 32:350-7. 2004..To determine whether caloric intake is associated with risk of nosocomial bloodstream infection in critically ill medical patients...
- Epidemiology of childhood tuberculosis: use and evaluation of the pediatric health information system to assess local and national incidenceDavid Siegel
Department of Epidemiology and Biostatistics, School of Public Health, The George Washington University, Washington, DC, USA
Pediatr Infect Dis J 30:428-30. 2011..9; 95% confidence interval 1.4-2.5). Of the 51 cases listed by PHIS as tuberculosis at CNMC between 2003 and 2007, 41 represented active tuberculosis validated by internal chart review, with a positive predictive value of 80%...
- An outbreak of Pseudomonas aeruginosa infections associated with flexible bronchoscopesArjun Srinivasan
Department of Hospital Epidemiology and Infection Control, Johns Hopkins Medical Institutions, Baltimore, MD, USA
N Engl J Med 348:221-7. 2003..Endoscopes, including bronchoscopes, are the medical devices most frequently associated with outbreaks of nosocomial infections. We investigated an outbreak of Pseudomonas aeruginosa infections after bronchoscopic procedures...
- A prospective trial of a novel, silicone-based, silver-coated foley catheter for the prevention of nosocomial urinary tract infectionsArjun Srinivasan
Department of Hospital Epidemiology and Infection Control, John Hopkins Hospital, Baltimore, Maryland, USA
Infect Control Hosp Epidemiol 27:38-43. 2006..To evaluate the efficacy of silicone-based, silver ion-impregnated urinary catheters in the prevention of nosocomial urinary tract infections (NUTIs)...
- Risk factors for development of vancomycin-resistant enterococcal bloodstream infection in patients with cancer who are colonized with vancomycin-resistant enterococciAimee K Zaas
Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21205, USA
Clin Infect Dis 35:1139-46. 2002..05-19.7), and acute renal failure (RR, 3.10; 95% CI, 1.07-8.93). Strategies for preventing VRE bloodstream infection in VRE-colonized patients with cancer should include limiting vancomycin use and, perhaps, gastrointestinal procedures...
- Implementation and impact of a consensus diagnostic and management algorithm for complicated pneumonia in childrenDinesh Pillai
Division of Pediatric Pulmonary Medicine, Children s National Medical Center, Washington, DC 20010, USA
J Investig Med 59:1221-7. 2011..We proposed that algorithm implementation would reduce use of computed tomography (CT) for diagnosis of pleural infection, thereby decreasing radiation exposure, without increased adverse outcomes...
- A prospective study to determine whether cover gowns in addition to gloves decrease nosocomial transmission of vancomycin-resistant enterococci in an intensive care unitArjun Srinivasan
Division of Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 5425, USA
Infect Control Hosp Epidemiol 23:424-8. 2002....
- Ability of physicians to diagnose and manage illness due to category A bioterrorism agentsSara E Cosgrove
Division of Infectious Disease, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Intern Med 165:2002-6. 2005..Physicians' ability to diagnose and care for patients presenting after a bioterror event is unknown. The role of online case-based didactics to measure and improve knowledge in the diagnosis and treatment of these patients is unknown...
- Application of a modified microbiologic criterion for identifying pediatric ventilator-associated pneumoniaPaulina Mariki
Division of Pediatric Infectious Diseases, Children s National Medical Center, Washington, DC
Am J Infect Control 42:1079-83. 2014..Prevention of ventilator-associated pneumonia (VAP) is a major patient safety goal, but accurate identification of VAP in pediatric patients remains challenging...
- Analysis of clinical parameters and cardiac magnetic resonance imaging as predictors of outcome in pediatric myocarditisShagun Sachdeva
Graduate Medical Education, Department of Pediatrics, Children s National Health System, Washington, District of Columbia
Am J Cardiol 115:499-504. 2015..In conclusion, this study provides data from a large cohort of pediatric myocarditis patients. A presenting EF <30%, peak BNP >10,000 ng/L, and cardiac MRI late enhancement were identified as predictors of poor outcomes. ..
- Comparison of the missing-indicator method and conditional logistic regression in 1:m matched case-control studies with missing exposure valuesXianbin Li
Department of Population and Family Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Am J Epidemiol 159:603-10. 2004..Overall, compared with the missing-indicator method, conditional logistic regression provided a slight advantage in terms of bias and coverage probability, at the cost of slightly reduced statistical power and efficiency...
- Varying rates of Clostridium difficile-associated diarrhea at prevention epicenter hospitalsSeJean Sohn
Infection Control, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Infect Control Hosp Epidemiol 26:676-9. 2005..Clostridium difficile-associated diarrhea (CDAD) causes substantial healthcare-associated morbidity. Unlike other common healthcare-associated pathogens, little comparative information is available about CDAD rates in hospitalized patients...
- Changing epidemiology of Clostridium difficile-associated disease in childrenLacey Benson
Case Western School of Medicine, Cleveland, OH, USA
Infect Control Hosp Epidemiol 28:1233-5. 2007..To determine temporal trends in the incidence rate for Clostridium difficile-associated disease (CDAD) in a pediatric patient population...
- Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalizationRebecca H Sunenshine
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 13:97-103. 2007..5, 95% CI 1.2-5.4 and OR 4.2, 95% CI 1.5-11.6] respectively). Increased hospitalization associated with MDR Acinetobacter infection emphasizes the need for infection control strategies to prevent cross-transmission in healthcare settings...
- Recommendations for surveillance of Clostridium difficile-associated diseaseL Clifford McDonald
Centers for Disease Control and Prevention, Atlanta, GA, USA
Infect Control Hosp Epidemiol 28:140-5. 2007..However, the understanding of the magnitude of and reasons for this change is currently hampered by the lack of standardized surveillance methods...