Sarah E Soden

Summary

Affiliation: Children's Mercy Hospital
Country: USA

Publications

  1. ncbi request reprint Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders
    Sarah E Soden
    Center for Pediatric Genomic Medicine, Children s Mercy Kansas City, Kansas City, MO 64108, USA Department of Pediatrics, Children s Mercy Kansas City, Kansas City, MO 64108, USA School of Medicine, University of Missouri Kansas City, Kansas City, MO 64108, USA
    Sci Transl Med 6:265ra168. 2014
  2. ncbi request reprint Nutrition, physical activity, and bone mineral density in youth with autistic spectrum disorders
    Sarah E Soden
    Section of Developmental and Behavioral Sciences, Department of Pediatrics, Children s Mercy Hospitals and Clinics, Kansas City, MO 64108, USA
    J Dev Behav Pediatr 33:618-24. 2012
  3. ncbi request reprint 24-hour provoked urine excretion test for heavy metals in children with autism and typically developing controls, a pilot study
    Sarah E Soden
    Section of Behavioral and Developmental Sciences, Children s Mercy Hospital and Assistant Professor of Pediatrics, University of Missouri Kansas City School of Medicine Kansas City, Missouri USA
    Clin Toxicol (Phila) 45:476-81. 2007
  4. ncbi request reprint Diagnosis of mitochondrial disorders by concomitant next-generation sequencing of the exome and mitochondrial genome
    Darrell L Dinwiddie
    Center for Pediatric Genomic Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Genomics 102:148-56. 2013
  5. pmc De novo frameshift mutation in ASXL3 in a patient with global developmental delay, microcephaly, and craniofacial anomalies
    Darrell L Dinwiddie
    Center for Pediatric Genomic Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA
    BMC Med Genomics 6:32. 2013
  6. ncbi request reprint Molecular diagnosis of infantile onset inflammatory bowel disease by exome sequencing
    Darrell L Dinwiddie
    Center for Pediatric Genomic Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA Department of Pediatrics, Children s Mercy Hospital, Kansas City, MO 64108, USA Department of Pathology, Children s Mercy Hospital, Kansas City, MO 64108, USA School of Medicine, University of Missouri Kansas City, Kansas City, MO 64110, USA Department of Pediatrics, University of New Mexico Health Science Center, Albuquerque, NM 87131, USA Clinical Translational Science Center, University of New Mexico, Albuquerque, NM 87131, USA Electronic address
    Genomics 102:442-7. 2013
  7. pmc Adopting orphans: comprehensive genetic testing of Mendelian diseases of childhood by next-generation sequencing
    Stephen F Kingsmore
    Children s Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Expert Rev Mol Diagn 11:855-68. 2011
  8. ncbi request reprint 15q11.2 proximal imbalances associated with a diverse array of neuropsychiatric disorders and mild dysmorphic features
    Ahmed T Abdelmoity
    Section of Neurology, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Dev Behav Pediatr 33:570-6. 2012

Collaborators

  • Stephen F Kingsmore
  • Shihui Yu
  • Darrell L Dinwiddie
  • Carol J Saunders
  • Neil A Miller
  • Emily G Farrow
  • Laurie D Smith
  • Ahmed T Abdelmoity
  • Jignesh Dalal
  • Julie A Bass
  • Andrea M Atherton
  • Julia M Bracken
  • Meghan E Strenk
  • David L Zwick
  • Kathy Christenson
  • Charles C Roberts
  • Vivekanand Singh
  • Carol A Daniel
  • Sarah S Nyp
  • Jean Baptiste Lepichon

Detail Information

Publications8

  1. ncbi request reprint Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders
    Sarah E Soden
    Center for Pediatric Genomic Medicine, Children s Mercy Kansas City, Kansas City, MO 64108, USA Department of Pediatrics, Children s Mercy Kansas City, Kansas City, MO 64108, USA School of Medicine, University of Missouri Kansas City, Kansas City, MO 64108, USA
    Sci Transl Med 6:265ra168. 2014
    ..It is suggested that initial diagnostic evaluation of children with NDD should include trio WGS or WES, with extension of accelerated sequencing modalities to high-acuity patients. ..
  2. ncbi request reprint Nutrition, physical activity, and bone mineral density in youth with autistic spectrum disorders
    Sarah E Soden
    Section of Developmental and Behavioral Sciences, Department of Pediatrics, Children s Mercy Hospitals and Clinics, Kansas City, MO 64108, USA
    J Dev Behav Pediatr 33:618-24. 2012
    ..The purpose of this study was to assess the BMD of a clinical sample of 10- to 18-year olds with ASD, and the nutrition and physical activity correlates of skeletal health in this population...
  3. ncbi request reprint 24-hour provoked urine excretion test for heavy metals in children with autism and typically developing controls, a pilot study
    Sarah E Soden
    Section of Behavioral and Developmental Sciences, Children s Mercy Hospital and Assistant Professor of Pediatrics, University of Missouri Kansas City School of Medicine Kansas City, Missouri USA
    Clin Toxicol (Phila) 45:476-81. 2007
    ..The oral chelator meso-2,3-dimercaptosuccinic acid (DMSA) can be used diagnostically to mobilize heavy metals from extravascular pools, enhancing the identification of individuals who have a chelatable body burden...
  4. ncbi request reprint Diagnosis of mitochondrial disorders by concomitant next-generation sequencing of the exome and mitochondrial genome
    Darrell L Dinwiddie
    Center for Pediatric Genomic Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Genomics 102:148-56. 2013
    ..We suggest that additional studies should be conducted to evaluate exome sequencing as a primary diagnostic test for mitochondrial diseases, including those due to mtDNA mutations. ..
  5. pmc De novo frameshift mutation in ASXL3 in a patient with global developmental delay, microcephaly, and craniofacial anomalies
    Darrell L Dinwiddie
    Center for Pediatric Genomic Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA
    BMC Med Genomics 6:32. 2013
    ..In particular, whole exome and genome sequencing of families has been particularly useful in discovering de novo germline mutations as the cause of both rare diseases and complex disorders...
  6. ncbi request reprint Molecular diagnosis of infantile onset inflammatory bowel disease by exome sequencing
    Darrell L Dinwiddie
    Center for Pediatric Genomic Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA Department of Pediatrics, Children s Mercy Hospital, Kansas City, MO 64108, USA Department of Pathology, Children s Mercy Hospital, Kansas City, MO 64108, USA School of Medicine, University of Missouri Kansas City, Kansas City, MO 64110, USA Department of Pediatrics, University of New Mexico Health Science Center, Albuquerque, NM 87131, USA Clinical Translational Science Center, University of New Mexico, Albuquerque, NM 87131, USA Electronic address
    Genomics 102:442-7. 2013
    ..Exome sequencing can be an effective tool to aid in the molecular diagnosis of pediatric-onset IBD. We provide additional evidence of the safety and benefit of HSCT for patients with IBD due to mutations in the IL10RA gene...
  7. pmc Adopting orphans: comprehensive genetic testing of Mendelian diseases of childhood by next-generation sequencing
    Stephen F Kingsmore
    Children s Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Expert Rev Mol Diagn 11:855-68. 2011
    ..These advances will be reviewed in the setting of a recently developed test for 592 autosomal recessive and X-linked diseases...
  8. ncbi request reprint 15q11.2 proximal imbalances associated with a diverse array of neuropsychiatric disorders and mild dysmorphic features
    Ahmed T Abdelmoity
    Section of Neurology, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Dev Behav Pediatr 33:570-6. 2012
    ..In addition, possible etiological effects of 15q11.2 BP1-BP2 duplication in neuropsychiatric disorders are proposed...